The effect of strontium doped Zn-Ca-P(ZCP)coating by chemical conversion technique on the biodegradation of AZ31 alloy was evaluated.The coating formed with 1.5 wt.%Sr and 20 min phosphating time at 50℃ with pH 2.5 c...The effect of strontium doped Zn-Ca-P(ZCP)coating by chemical conversion technique on the biodegradation of AZ31 alloy was evaluated.The coating formed with 1.5 wt.%Sr and 20 min phosphating time at 50℃ with pH 2.5 completely covers the alloy surface.The Sr doped coated sample also showed very low evolved hydrogen gas and pH change than the ZCP coatings suggested that the degradation of the alloy was extremely controlled.The in vitro bioactivity studies in simulated body fluid exhibits deposition of calcium phosphate phases with Ca/P ratio of 1.55 which is close to that of hydroxyapatite,mineral component of bone.Cytotoxicity evaluation with L929 cells showed higher cell viability of the Sr doped coatings compared to ZCP coatings.展开更多
The binary Mg-Ca alloys are drawing increasing attention as temporary implant materials because of their excellent biocompatibility,biodegradability,and good mechanical properties.However,their applications are limite...The binary Mg-Ca alloys are drawing increasing attention as temporary implant materials because of their excellent biocompatibility,biodegradability,and good mechanical properties.However,their applications are limited due to their high degradation rates in the human physiological environment,the consequent release of hydrogen gas,and rapid loss in mechanical properties.Furthermore,biocompatibility depends upon the degradability of the material.Various researchers have demonstrated that these issues can be addressed by control of Ca content,thermo-mechanical processing to obtain suitable microstructures,deposition of surface coatings,etc.In this manuscript,a detailed review of published literature on Mg-Ca alloys is presented.The challenges and future directions of research in this area are also described.展开更多
文摘The effect of strontium doped Zn-Ca-P(ZCP)coating by chemical conversion technique on the biodegradation of AZ31 alloy was evaluated.The coating formed with 1.5 wt.%Sr and 20 min phosphating time at 50℃ with pH 2.5 completely covers the alloy surface.The Sr doped coated sample also showed very low evolved hydrogen gas and pH change than the ZCP coatings suggested that the degradation of the alloy was extremely controlled.The in vitro bioactivity studies in simulated body fluid exhibits deposition of calcium phosphate phases with Ca/P ratio of 1.55 which is close to that of hydroxyapatite,mineral component of bone.Cytotoxicity evaluation with L929 cells showed higher cell viability of the Sr doped coatings compared to ZCP coatings.
文摘The binary Mg-Ca alloys are drawing increasing attention as temporary implant materials because of their excellent biocompatibility,biodegradability,and good mechanical properties.However,their applications are limited due to their high degradation rates in the human physiological environment,the consequent release of hydrogen gas,and rapid loss in mechanical properties.Furthermore,biocompatibility depends upon the degradability of the material.Various researchers have demonstrated that these issues can be addressed by control of Ca content,thermo-mechanical processing to obtain suitable microstructures,deposition of surface coatings,etc.In this manuscript,a detailed review of published literature on Mg-Ca alloys is presented.The challenges and future directions of research in this area are also described.
