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表浅性膀胱癌的免疫治疗
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作者 B.J.Schmitz-Drger S.O.Schattka +1 位作者 t.ebert 杨为民 《德国医学》 CAS 1994年第3期145-146,共2页
分期、恶性程度和多病灶出现,在表浅性膀胱癌是复发与进展的重要预后指标。进展是不可避免的,因此需相应的治疗措施。近百年来对各种疫苗对肿瘤的经过进行研究观察,通过对免疫系统的有目的刺激,可诱导出免疫反应发挥抗肿瘤作用。某些肿... 分期、恶性程度和多病灶出现,在表浅性膀胱癌是复发与进展的重要预后指标。进展是不可避免的,因此需相应的治疗措施。近百年来对各种疫苗对肿瘤的经过进行研究观察,通过对免疫系统的有目的刺激,可诱导出免疫反应发挥抗肿瘤作用。某些肿瘤内虽可见到一些免疫系统的细胞浸润,然而这种浸润与抗肿瘤作用的关系仍不明瞭;对效应细胞与抗肿瘤反应的机制所知也少。需要解决的是:最佳免疫治疗制剂、适宜剂量、使用间隔时间。 展开更多
关键词 膀胱肿瘤 免疫疗法
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Reflection of intense laser light from microstructured targets as a potential diagnostic of laser focus and plasma temperature
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作者 J.Jarrett M.King +11 位作者 R.J.Gray N.Neumann L.Dhl C.D.Baird t.ebert M.Hesse A.Tebartz D.R.Rusby N.C.Woolsey D.Neely M.Roth P.McKenna 《High Power Laser Science and Engineering》 SCIE CAS CSCD 2019年第1期10-16,共7页
The spatial-intensity profile of light reflected during the interaction of an intense laser pulse with a microstructured target is investigated experimentally and the potential to apply this as a diagnostic of the int... The spatial-intensity profile of light reflected during the interaction of an intense laser pulse with a microstructured target is investigated experimentally and the potential to apply this as a diagnostic of the interaction physics is explored numerically. Diffraction and speckle patterns are measured in the specularly reflected light in the cases of targets with regular groove and needle-like structures, respectively, highlighting the potential to use this as a diagnostic of the evolving plasma surface. It is shown, via ray-tracing and numerical modelling, that for a laser focal spot diameter smaller than the periodicity of the target structure, the reflected light patterns can potentially be used to diagnose the degree of plasma expansion, and by extension the local plasma temperature, at the focus of the intense laser light. The reflected patterns could also be used to diagnose the size of the laser focal spot during a high-intensity interaction when using a regular structure with known spacing. 展开更多
关键词 high power LASER laser-solid INTERACTIONS plasma temperature diagnosis
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