Hollow-fiber liquid-phase microextraction(HF-LPME)and electromembrane extraction(EME)are miniaturized extraction techniques,and have been coupled with various analytical instruments for trace analysis of heavy metals,...Hollow-fiber liquid-phase microextraction(HF-LPME)and electromembrane extraction(EME)are miniaturized extraction techniques,and have been coupled with various analytical instruments for trace analysis of heavy metals,drugs and other organic compounds,in recent years.HF-LPME and EME provide high selectivity,efficient sample cleanup and enrichment,and reduce the consumption of organic sol-vents to a few micro-liters per sample.HF-LPME and EME are compatible with different analytical in-struments for chromatography,electrophoresis,atomic spectroscopy,mass spectrometry,and electrochemical detection.HF-LPME and EME have gained significant popularity during the recent years.This review focuses on hollow fiber based techniques(especially HF-LPME and EME)of heavy metals and pharmaceuticals(published 2017 to May 2019),and their combinations with atomic spectroscopy,UV-VIS spectrophotometry,high performance liquid chromatography,gas chromatography,capillary elec-trophoresis,and voltammetry.展开更多
Electromembrane extraction(EME) is an analytical microextraction technique, where charged analytes(such as drug substances) are extracted from an aqueous sample(such as a biological fluid), through a supported liquid ...Electromembrane extraction(EME) is an analytical microextraction technique, where charged analytes(such as drug substances) are extracted from an aqueous sample(such as a biological fluid), through a supported liquid membrane(SLM) comprising a water immiscible organic solvent, and into an aqueous acceptor solution. The driving force for the extraction is an electrical potential(dc) applied across the SLM. In this paper, EME is reviewed. First, the principle for EME is explained with focus on extraction of cationic and anionic analytes, and typical performance data are presented. Second, papers published in 2016 are reviewed and discussed with focus on(a) new SLMs,(b) new support materials for the SLM,(c) new sample additives improving extraction,(d) new technical configurations,(e) improved theoretical understanding, and(f) pharmaceutical new applications. Finally, important future research objectives and directions are defined for further development of EME, with the aim of establishing EME in the toolbox of future analytical laboratories.展开更多
基金supported by the Higher education commission of Pakistan(NRPU No.20-3925/R&D/NRPU/HEC/2014)PAK-US science and technology cooperation(Pak-US No6-4/PAK-US/HEC/2015/04)Pakistan science foundation joint research projects with MSRT,Iran(No.PSF-MSRT/Env/KP-AWKUM)。
文摘Hollow-fiber liquid-phase microextraction(HF-LPME)and electromembrane extraction(EME)are miniaturized extraction techniques,and have been coupled with various analytical instruments for trace analysis of heavy metals,drugs and other organic compounds,in recent years.HF-LPME and EME provide high selectivity,efficient sample cleanup and enrichment,and reduce the consumption of organic sol-vents to a few micro-liters per sample.HF-LPME and EME are compatible with different analytical in-struments for chromatography,electrophoresis,atomic spectroscopy,mass spectrometry,and electrochemical detection.HF-LPME and EME have gained significant popularity during the recent years.This review focuses on hollow fiber based techniques(especially HF-LPME and EME)of heavy metals and pharmaceuticals(published 2017 to May 2019),and their combinations with atomic spectroscopy,UV-VIS spectrophotometry,high performance liquid chromatography,gas chromatography,capillary elec-trophoresis,and voltammetry.
基金The Research Council of Norway is acknowledged for financial support through Grant 231917
文摘Electromembrane extraction(EME) is an analytical microextraction technique, where charged analytes(such as drug substances) are extracted from an aqueous sample(such as a biological fluid), through a supported liquid membrane(SLM) comprising a water immiscible organic solvent, and into an aqueous acceptor solution. The driving force for the extraction is an electrical potential(dc) applied across the SLM. In this paper, EME is reviewed. First, the principle for EME is explained with focus on extraction of cationic and anionic analytes, and typical performance data are presented. Second, papers published in 2016 are reviewed and discussed with focus on(a) new SLMs,(b) new support materials for the SLM,(c) new sample additives improving extraction,(d) new technical configurations,(e) improved theoretical understanding, and(f) pharmaceutical new applications. Finally, important future research objectives and directions are defined for further development of EME, with the aim of establishing EME in the toolbox of future analytical laboratories.
