Reaching across multiple fields of focus,spanning from periodontistry to gastroenterology to neurobiology to behavior,interest in the influence of the microbiome in human physiology and pathology has risen over the pa...Reaching across multiple fields of focus,spanning from periodontistry to gastroenterology to neurobiology to behavior,interest in the influence of the microbiome in human physiology and pathology has risen over the past few decades.Microbiota co-exist in and on humans forming an evolutionarily symbiotic biological unit,a halobiont,in which disruptions in the relationship can occur through genomic alterations and mutations[1],The human microbiome consists of bacteria,viruses,fungi,and protozoans that contribute 450 times more genes to this relationship and slightly outnumber human host cells[2,3].The bacteria in the gastrointestinal(GI)tract are of the most interest and exist within five phyla:Bacteroidetes,Firmicutes,Pro-teobacteria,Actinobacteria,and Verrucomicrobi&.Within the Verrucomicrobia an interesting bacterium has emerged.展开更多
基金This insight was supported by Michigan Technological University Portage Health Foundation,America Heart Association(16PRE27780121)National Natural Science Foundation of China(31871150).
文摘Reaching across multiple fields of focus,spanning from periodontistry to gastroenterology to neurobiology to behavior,interest in the influence of the microbiome in human physiology and pathology has risen over the past few decades.Microbiota co-exist in and on humans forming an evolutionarily symbiotic biological unit,a halobiont,in which disruptions in the relationship can occur through genomic alterations and mutations[1],The human microbiome consists of bacteria,viruses,fungi,and protozoans that contribute 450 times more genes to this relationship and slightly outnumber human host cells[2,3].The bacteria in the gastrointestinal(GI)tract are of the most interest and exist within five phyla:Bacteroidetes,Firmicutes,Pro-teobacteria,Actinobacteria,and Verrucomicrobi&.Within the Verrucomicrobia an interesting bacterium has emerged.
