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Generation of radioisotopes for medical applications using high-repetition,high-intensity lasers
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作者 Katarzyna Liliana Batani Marcia R.D.Rodrigues +23 位作者 Aldo Bonasera Mattia Cipriani Fabrizio Consoli Francesco Filippi Massimiliano M.Scisciò Lorenzo Giuffrida Vasiliki Kantarelou stanislav stancek Roberto Lera Jose Antonio Pérez-Hernández Luca Volpe I.C.Edmond Turcu Matteo Passoni Davide Vavassori David Dellasega Alessandro Maffini Marine Huault Howel Larreur Louis Sayo Thomas Carriere Philippe Nicolai Didier Raffestin Diluka Singappuli Dimitri Batani 《High Power Laser Science and Engineering》 2025年第1期109-124,共16页
We used the PW high-repetition laser facility VEGA-3 at Centro de Láseres Pulsados in Salamanca,with the goal of studying the generation of radioisotopes using laser-driven proton beams.Various types of targets h... We used the PW high-repetition laser facility VEGA-3 at Centro de Láseres Pulsados in Salamanca,with the goal of studying the generation of radioisotopes using laser-driven proton beams.Various types of targets have been irradiated including in particular several targets containing boron to generateα-particles through the hydrogen–boron fusion reaction.We have successfully identifiedγ-ray lines from several radioisotopes created by irradiation using lasergeneratedα-particles or protons including^(43)Sc,^(44)Sc,^(48)Sc,^(7)Be,^(11)C and^(18)F.We show that radioisotope generation can be used as a diagnostic tool to evaluateα-particle generation in laser-driven proton–boron fusion experiments.We also show the production of^(11)C radioisotopes,≈6×10~6,and of^(44)Sc radioisotopes,≈5×10~4per laser shot.This result can open the way to develop laser-driven radiation sources of radioisotopes for medical applications. 展开更多
关键词 RADIOISOTOPES laser driven protons proton boron fusion gamma ray spectroscopy medical applications
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Real-time bremsstrahlung detector as a monitoring tool for laser–plasma proton acceleration
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作者 Valeria Istokskaia Benoit Lefebvre +10 位作者 Roberto Versaci Dragana B.Dreghici Domenico Doria Filip Grepl Veronika Olšovcová Francesco Schillaci stanislav stancek Maksym Tryus Andriy Velyhan Daniele Margarone Lorenzo Giuffrida 《High Power Laser Science and Engineering》 CSCD 2024年第5期28-38,共11页
Real-time evaluation of laser-driven byproducts is crucial for state-of-the-art facilities operating at high repetition rates.This work presents real-time measurements of hard X-rays(bremsstrahlung radiation) generate... Real-time evaluation of laser-driven byproducts is crucial for state-of-the-art facilities operating at high repetition rates.This work presents real-time measurements of hard X-rays(bremsstrahlung radiation) generated from the interaction of high-intensity laser pulses with solid targets in the target normal sheath acceleration regime using a scintillator stack detector. The detector offers insights into the effectiveness of laser–plasma interaction through measured fiuctuations in bremsstrahlung radiation temperature and scintillation light yield on a shot-to-shot basis. Moreover, a strong correlation of the bremsstrahlung measurements(i.e., temperature and yield) with the cutoff energy of laser-driven protons was observed. The scintillator stack detector serves not only as a diagnostic for online monitoring of the laser–plasma interaction but also as a promising tool for estimating proton energy fiuctuations in a non-disruptive manner, which is particularly important when direct proton source characterization is impractical, for example, during experiments aimed at irradiating user samples with the accelerated proton beam. 展开更多
关键词 bremsstrahlung radiation laser-driven proton acceleration real-time diagnostics scintillator stack detector
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