Eczema craquele, or asteatotic eczema, has been associated with malignant lymphoma although this is rare. Since 1986,we have observed seven patients, six men and one woman,mean age 71.5 years (range 43-86 years), with...Eczema craquele, or asteatotic eczema, has been associated with malignant lymphoma although this is rare. Since 1986,we have observed seven patients, six men and one woman,mean age 71.5 years (range 43-86 years), with systemic lymphoma and concurrent eczema craquele. Five patients had T-cell lymphoma, one had a B-cell lymphoma and one had Hodgkin’s disease. All patients shared several characteristics: (1) a synchronous onset of eczema craquele and lymphoma,(2) generalized eczema, (3)absence of alternative disease or conditions that could favour the onset of eczema craquele, and (4) eczema refractory to topical corticosteroids and emollients, but which resolved upon lymphoma remission and invariably recurred with the lymphoma relapse. All the patients except one died within 1 year, most with active lymphoma. The finding of recalcitrant generalized eczema craquele should prompt a search for lymphoma, particularly in older men. Lymphoma-associated eczema craquele has most characteristics of paraneoplastic syndromes and may be a hallmark of aggressive lymphoma.展开更多
We describe the unusual case of a 78- year- old woman consulting for extensive and painful wound leg ulcerations and calcifications secondary to CREST syndrome that was treated by extracorporeal shock wave lithotripsy...We describe the unusual case of a 78- year- old woman consulting for extensive and painful wound leg ulcerations and calcifications secondary to CREST syndrome that was treated by extracorporeal shock wave lithotripsy. This treatment was considered because of the severity of our patient’ s symptoms and her failure to respond to various medical and surgical treatment.展开更多
文摘Eczema craquele, or asteatotic eczema, has been associated with malignant lymphoma although this is rare. Since 1986,we have observed seven patients, six men and one woman,mean age 71.5 years (range 43-86 years), with systemic lymphoma and concurrent eczema craquele. Five patients had T-cell lymphoma, one had a B-cell lymphoma and one had Hodgkin’s disease. All patients shared several characteristics: (1) a synchronous onset of eczema craquele and lymphoma,(2) generalized eczema, (3)absence of alternative disease or conditions that could favour the onset of eczema craquele, and (4) eczema refractory to topical corticosteroids and emollients, but which resolved upon lymphoma remission and invariably recurred with the lymphoma relapse. All the patients except one died within 1 year, most with active lymphoma. The finding of recalcitrant generalized eczema craquele should prompt a search for lymphoma, particularly in older men. Lymphoma-associated eczema craquele has most characteristics of paraneoplastic syndromes and may be a hallmark of aggressive lymphoma.
文摘We describe the unusual case of a 78- year- old woman consulting for extensive and painful wound leg ulcerations and calcifications secondary to CREST syndrome that was treated by extracorporeal shock wave lithotripsy. This treatment was considered because of the severity of our patient’ s symptoms and her failure to respond to various medical and surgical treatment.
