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Epidemiological Aspects of Metastatic Relapse of Breast Cancer in an African Context
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作者 Jean Marc Dia Corneille Saki +5 位作者 Oyeladé Mouhideen Eric Bohoussou Moctar Touré Gerard Okon Privat Guié simplice anongba 《Open Journal of Obstetrics and Gynecology》 2017年第5期552-561,共10页
Objectives: This study aimed to describe the epidemiological characteristics of metastatic relapse in breast cancer at the University and Hospital Center of Treichville. Methodology: This is a cohort and retrospective... Objectives: This study aimed to describe the epidemiological characteristics of metastatic relapse in breast cancer at the University and Hospital Center of Treichville. Methodology: This is a cohort and retrospective study conducted from January 2000 to December 2015 on 178 patients with metastaticrelapse in breast cancer. Results: The prevalence of metastatic relapses was 49% and the patients had an average age of 53.4 years and among them, 91.6% received school education and 88.2% did not have a high socioeconomic level. The majority of initial tumors were in Stage III (47.8%), SBR III (47.2%), High Ki 67 (46.5%), Negative RH (79.3%), and HER2 negative (58%). Metastases were generally unique (62.9%), dominated by bone sites (36.6%), with an average occurrencedelay of 2.4 years. After the occurrence of metastases, the cumulative survival rate was 5% at 3 years, and nil at 5 years. Conclusion: Metastatic relapses were common with poor prognosis. 展开更多
关键词 BREAST Cancer Risk Factors METASTATIC RELAPSES
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Management of Women Infertility in Tropical Africa: The Experience of the Gynecology Department of University and Hospital Center of Treichville (Abidjan-Cote d’Ivoire)
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作者 Jean Marc Lamine Dia Eric Bohoussou +3 位作者 Edouard Nguessan Mouhideen Oyelade Privat Guié simplice anongba 《Open Journal of Obstetrics and Gynecology》 2017年第2期235-244,共10页
Objectives: This study aimed to clarify the etiology of women infertility and describe their management in our service with limited technical equipment. Methodology: We conducted a retrospective and descriptive study ... Objectives: This study aimed to clarify the etiology of women infertility and describe their management in our service with limited technical equipment. Methodology: We conducted a retrospective and descriptive study on 175 women treated for infertility and followed in the gynecology services of the university Hospital center of Treichville from 1st January 2012 to 31st December 2014. Results: During the study, we recorded 12072 consultations in gynecology including 1582 (13.1%) cases of infertility, but only 175 cases were selected for this study. The patients had an average age of 31.3 years and an average socio-economic level in general (78.9%). The etiologies were found in 79.4% of patients, dominated by classical abnormalities: uterine (fibroids: 41.8%), hormonal, tubo peritoneal (5%). We also found some unusual pathologies related to cultural practices (female genital mutilation, caustic stenosis of the vagina). The surgery was performed in several patients, including myomectomy by laparotomy (46.6%), laparoscopy, hysteroscopy and vaginal surgeries. As to drug treatment, they were various combinations, and the ovarian stimulation practices (62.3%) and induction of ovulation (47.2%) were common. The result of this support has been marked by the occurrence of 74 pregnancies (42.3%), with the birth of healthy children in the majority of cases (95.9%). Conclusion: The management of infertile women was frequent and yielded encouraging results despite our limited technical equipment. 展开更多
关键词 WOMEN INFERTILITY ETIOLOGIES Treatment
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Management of Inflammatory Breast Cancers in Subsaharian Africa Context
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作者 Jean Marc Dia Lydie Estelle Djanhan +6 位作者 C. Saki Mouhideen Oyéladé Gérard Okon Abdoulaye Camara Abdoulaye Diallo Privat Guié simplice anongba 《Open Journal of Obstetrics and Gynecology》 2018年第1期20-30,共11页
Objective: To report the experience of Gynecology Department of the University Hospital of Treichville in the management of the inflammatory breast cancers. Methodology: We conducted a retrospective and descriptive st... Objective: To report the experience of Gynecology Department of the University Hospital of Treichville in the management of the inflammatory breast cancers. Methodology: We conducted a retrospective and descriptive study on cases of the inflammatory breast cancers managed in the Gynecology Department of the University Hospital of Treichville, from January 2011 to December 2015. Results: We collected 44 cases of inflammatory breast cancer representing 17.9% of all breast cancers. The average age of patients was 46.5 years (32 - 70 years) and among them, the majority had inadequate socioeconomic level (90.9%). The risk factor for cancer found in the majority of patients was the age of first menstrual periods before the age of 12 years (52.3%). The average consultation time was long (10 months) and several patients had extensive inflammatory signs (38.6%), with lymph node involvement (84.1%) and metastases (36.4%). At the histological analysis, the most common type was invasive ductal carcinoma (81.8%), SBR grade III (54.5%). Regarding treatment, mastectomy according to Patey associated with a chemotherapy was performed in 22.7% cases. The evolution has been marked by an overall 5-year survival of 20%. Conclusion: The management of inflammatory breast cancers was late and incomplete in our service making poor prognosis. 展开更多
关键词 INFLAMMATORY Brest CANCERS EPIDEMIOLOGY DIAGNOSIS Treatment
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Occurrence Delays of Metastatic Relapses of Breast Cancers Treated at University Hospital of Treichville (Abidjan-Cote d’Ivoire)
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作者 Lydie Estelle Djanhan Jean Marc Dia +4 位作者 Boston Mian Mouhideen Oyelade Aboulaye Diallo Privat Guié simplice anongba 《Journal of Cancer Therapy》 2017年第11期924-932,共9页
Objective: Describe the occurrence delays of metastatic relapses of breast cancer based on the characteristics of the original tumor. Methodology: This is a retrospective and cohort study conducted from January 2000 t... Objective: Describe the occurrence delays of metastatic relapses of breast cancer based on the characteristics of the original tumor. Methodology: This is a retrospective and cohort study conducted from January 2000 to December 2015 on patients with metastatic relapse of breast cancer. Results: Out of 178 patients collected, the metastatic relapses were estimated at 49%, occurring in patients with an average age of 53.4 years. The majority of the patients was educated (91.6%) and did not have a high socioeconomic level (88.2%). The initial tumors were mainly at a clinical stage III (47.8%), SBR grade III (47.2%), high index Ki 67 (46.5%), negative RH (79.3%) and HER2 negative (58%). Metastases were unique in general (62.9%), dominated by bone locations (36.6%), with an average age of occurrence of 2.4 years. After the occurrence of these metastases, the cumulative survival rate was 5% at 3 years, and zero to 5 years. Conclusion: Metastatic relapses were common with poor prognosis. 展开更多
关键词 BREAST Cancer Risk Factors METASTATIC RELAPSES
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Breast Cancers in Young Woman under 40 Years in Sub-Saharan Africa: Experience of the Gynecology Department of the University and Hospital Center of Treichville (Abidjan—Cote d’Ivoire)
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作者 Jean Marc Dia Moctar Touré +5 位作者 Ignace Yao Eric Bohoussou Corneil Saki Mouhideen Oyelade Gérard Okon simplice anongba 《Journal of Cancer Therapy》 2017年第8期714-725,共12页
Objective: To describe the epidemiological, clinical and therapeutic characteristics of women under 40 years followed for breast cancer. Method: This is a retrospective and cohort study with descriptive purpose conduc... Objective: To describe the epidemiological, clinical and therapeutic characteristics of women under 40 years followed for breast cancer. Method: This is a retrospective and cohort study with descriptive purpose conducted over 10 years on the management of breast cancer in 105 patients under 40 years in the Gynecology Service of the University and Hospital Center of Treichville. Results: The incidence of breast cancer in women under 40 years was 8.4%, and the majority of patients were over 35 years old (64.8%) and had a low socioeconomic level (61.7%). Some patients had classic risk factors for breast cancer: menarche before 12 years (48.6%), nulliparity (20%), family history of breast cancer (1.9%). The discovery of a breast abnormality was made by patients in 97.1% of the cases. Cancers were either isolated (92.4%) or associated with pregnancy (5.7%) or bilateral (1.9%). The majority of cancers were infiltrating ductal carcinomas (86.7%), of SBR II grade (69%). Patients generally benefited from a mastectomy with axillary dissection, framed by chemotherapy. The global survival at 10 years was 5%. Conclusion: This study allowed us to confirm that breast cancers in younger women were a reality in our country and posed us enormous difficulties in their management. 展开更多
关键词 BREAST Cancer YOUNG Women Diagnosis Treatment
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Mother-to-Child HIV Transmission Factors in Exposed Children at University Hospital Center of Treichville (Abidjan, Cote d’Ivoire)
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作者 Edouard N’Guessan Jean Marc Lamine Dia +3 位作者 Mouhideen Oyelade Ignace Yao Privat Guié simplice anongba 《Open Journal of Obstetrics and Gynecology》 2017年第12期1198-1208,共11页
Background: The elimination of HIV transmission from mother to child is currently possible. Cote d’Ivoire, which has a 4.6% HIV prevalence among women, is one of 22 pilot countries for the elimination of mother-to-ch... Background: The elimination of HIV transmission from mother to child is currently possible. Cote d’Ivoire, which has a 4.6% HIV prevalence among women, is one of 22 pilot countries for the elimination of mother-to-child transmission of HIV. Since 2015, Cote d’Ivoire has adopted new strategies according to the WHO B+ guidelines. Objective: To identify factors associated with mother-to-child HIV transmission in children born of seropositive mothers managed at Treichville university hospital. Material and methods: A case-control study was conducted in the obstetrics department at Treichville university hospital, between January 2013 and December 2015. It involved children born to mothers infected with HIV, whose first PCR (Polymerase Chain Reaction) result was available during this period. A standardized questionnaire on data related to exposed children and their mother was used. Factors associated with mother-to-child HIV transmission were investigated using logistic regression. Results: A total of 214 HIV-exposed children were included in the study with a sex ratio of 0.9. The majority of the children were born by vaginal route (52.8%) and received post-exposure prophylaxis (88.3%) and replacement feed (51.9%). Their mothers received antiretroviral therapy during pregnancy in 45.3% of the cases. The first PCR was performed at the sixth week of life in 52.3% of cases. The prevalence of HIV infection in exposed children was 7.5% (95% CI = 4.5% - 11.8%). In multivariate analysis, the absence of antiretroviral prophylaxis in children [aOR = 4.3, 95% (1.2 to 15.6), p = 0.03], the mixed feed [aOR = 3.8, 95% (1.1 - 13.1), p < 0.03], the failure to take antiretroviral regimen during pregnancy [aOR = 8.0, 95% CI (1.9 - 32.4), p < 0.003], were associated with mother-child HIV transmission. Conclusion: The mother-to-child HIV transmission rate remains high in our practice. Strategies to reduce situations that do not comply with current recommendations should be considered to prevent mother-to-child HIV transmission. 展开更多
关键词 HIV-Exposed CHILDREN Mother-to-Child Transmission DBS/PCR
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Endometriosis Revealed by Recurrent Hemorrhagic Ascites
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作者 Edouard N’Guessan N’Goran Kouamé +3 位作者 Jean Marc Lamine Dia Franc Gbeli Privat Guie simplice anongba 《Open Journal of Obstetrics and Gynecology》 2017年第12期1160-1165,共6页
Ascites is a rare manifestation of endometriosis. The case reported is that of a 26-year-old woman with recurrent massive hemorrhagic ascites. The analysis of biopsy specimens made at laparoscopy confirmed the diagnos... Ascites is a rare manifestation of endometriosis. The case reported is that of a 26-year-old woman with recurrent massive hemorrhagic ascites. The analysis of biopsy specimens made at laparoscopy confirmed the diagnosis. The report noted pelvic endometriosis associated but there was no umbilical or pleural involvement. The evolution was favorable under a long-term hormone treatment (by GnRH analogues) with relay through continuous estrogen-progestogen. The diagnostic and therapeutic difficulties of this rare form of endometriosis are presented through a review of the literature. 展开更多
关键词 ENDOMETRIOSIS HEMORRHAGIC ASCITES MANAGEMENT
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Management of an Unusual Complication of Uterine Fibroids in the Gynecological Department of the University and Hospital Center of Treichville (Cote D’ivoire): About 2 Cases of Non-Puerperal Uterine Inversion
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作者 Eric Bohoussou Lamine Dia +3 位作者 Ignace Yao Kacou Anzoua Privat Guie simplice anongba 《Open Journal of Obstetrics and Gynecology》 2017年第2期220-225,共6页
Uterine inversion is rare. It is classically described as a complication of the delivery period. Non-puerperal uterine inversion is exceptional and usually results from a tumor implanted on fundus of the uterus. We re... Uterine inversion is rare. It is classically described as a complication of the delivery period. Non-puerperal uterine inversion is exceptional and usually results from a tumor implanted on fundus of the uterus. We report two cases of non-puerperal uterine inversion caused by fundal submucosal myoma. Its diagnosis can be difficult and a high index of clinical suspicion is required to make a prompt diagnosis. The delayed diagnosis observed in our cases, caused uterine necrosis, which was managed by hysterectomy. The patients’ post-operative course was uneventful. 展开更多
关键词 Non-Puerperal UTERINE Inversion MYOMA HYSTERECTOMY
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