Objective： To observe the difference in clinical efficacy between governor vessel-unblocking and mind- regulating acupuncture therapy combined with conventional rehabilitation therapy and simply conventional rehabili...Objective： To observe the difference in clinical efficacy between governor vessel-unblocking and mind- regulating acupuncture therapy combined with conventional rehabilitation therapy and simply conventional rehabilitation therapy for sensory and motor dysfunction of patients with spinal cord injury. Methods： Forty patients with spinal cord injury （SCI） were randomly assigned into rehabilitation combined with acupuncture group （group A） and rehabilitation group （group B）, with 20 patients in each group. In group A, governor vessel-unblocking and mind-regulating acupuncture therapy combined with conventional rehabilitation therapy was adopted, and Baihui（百会 GV 20）, Fengffu （风府GV 16）, Dazhui （大椎GV 14）, Zhiyang （至阳GV 9）, Mingmen （命门 GV 4） and Yfioyangguan （腰阳关 GV 3） were adopted as the main acupoints. Conventional rehabilitation therapy was also applied, including the rehabilitation training of joint, motion, respiration, urinary bladder and intestinal tract. In group B, conventional rehabilitation therapy was adopted as same as the group A. Treatment in the two groups was conducted for once a day, 6 times a week, and 12 weeks in total. ASIA motor score （MS）, ASIA sensory score （SS） and activity of daily living （ADL） score of patients in the two groups were observed before and after the treatment. Results： Before treatment, the differences in MS, SS and ADL score of patients in the two groups were not statistically significant （all P 〉 0.05）, and the results were comparable. After treatment, MS, SS and ADL score of patients in the two groups were all higher than that before the treatment （all P 〈 0.05）, and MS, SS and ADL score of the patients in group A were all higher than that in group B （all P 〈 0.05）. Conclusion： The curative effect of governor vessel-unblocking and mind-regulating acupuncture therapy combined with conventional rehabilitation therapy was superior to that of simply conventional rehabilitation therapy in the treatment of sensory and motor dysfunction of the patients with SCI.展开更多
Background Hypertension is widely acknowledged as a significant contributory factor to the heightened risk of intracranial aneurysm rupture.Nevertheless,the impact of hypertension management on the outcomes subsequent...Background Hypertension is widely acknowledged as a significant contributory factor to the heightened risk of intracranial aneurysm rupture.Nevertheless,the impact of hypertension management on the outcomes subsequent to aneurysmal subarachnoid haemorrhage(aSAH),particularly concerning the severity of aSAH,remains an underexplored area.Methods We conducted a retrospective analysis using data from a prospectively multicentre cohort of 4545 patients with aSAH in China.Premorbid hypertension status and the utilisation of antihypertensive medications prior to admission were set as key exposure factors.The primary outcomes encompassed unfavourable clinical grading scales observed on admission.Employing multivariable logistic regression,we explored the association between premorbid hypertension status,preadmission use of renin-angiotensin aldosterone system(RAAS)inhibitors and unfavourable clinical grading scales.Results In comparison to patients with normal blood pressure,only uncontrolled hypertension demonstrated a significant and independent association with an elevated risk of poor outcomes on the Hunt-Hess scale(OR=1.799,95%CI 1.413 to 2.291,p<0.001)and the World Federation of Neurological Surgeons(WFNS)scale(OR=1.721,95%CI 1.425 to 2.079,p<0.001).Furthermore,the antecedent use of RAAS inhibitors before admission was markedly and independently linked to a diminished risk of adverse outcomes on the Hunt-Hess scale(OR=0.653,95%CI 0.430 to 0.992,p=0.046)and the WFNS scale(OR=0.656,95%CI 0.469 to 0.918,p=0.014).Conclusions Uncontrolled hypertension markedly elevates the risk of adverse clinical outcomes following an aSAH.Conversely,the preadmission utilisation of RAAS inhibitors demonstrates a noteworthy association with a favourable clinical outcome after aSAH.展开更多
Objectives This study aimed to design and evaluate a detection system for the accidental dislodgement of head-and-neck medical supplies through hand position recognition and tracking in Intensive Care Unit(ICU)patient...Objectives This study aimed to design and evaluate a detection system for the accidental dislodgement of head-and-neck medical supplies through hand position recognition and tracking in Intensive Care Unit(ICU)patients.Methods We conducted a single-center,prospective,parallel-group feasibility randomized controlled trial.We recruited 80 participants using convenience sampling from the ICU of a hospital in Ningbo City,Zhejiang Province,between March 2025 and June 2025,and they were randomly assigned to either the control group(routine care)or the intervention group(routine care plus image recognition-based detection system).The system continuously tracked patients’hand positions via bedside cameras and generated real-time alarms when hands entered predefined risk zones,notifying on-duty nurses to enable early intervention.System stability was assessed by continuous system uptime;system performance and clinical feasibility were evaluated by the frequencies of risk actions and accidental dislodgement of medical supplies(ADMS).Results All 80 participants completed the intervention,with 40 patients in each group.The baseline characteristics and median observation time of the two groups were balanced(intervention group:48 h/patient vs.control group:49 h/patient).Compared with the control group,the intervention group showed fewer ADMS(2/40 vs.9/40)and detected more risk actions per 100 h(36 vs.25);all system-detected events had corroborating images with complete concordance on manual review,and all nurse-recorded hand-contact events were accurately captured.Conclusions The study demonstrated that the image recognition-based detection system can function stably in clinical settings,providing accurate and continuous surveillance while supporting the early detection of risk actions.By reducing the observation burden and offering real-time cognitive support,the system complements routine nursing care and serves as an additional safety measure in ICU practice.With further optimization and larger multicenter validation,this approach could have the potential to make a significant contribution to the development of smart ICUs and the broader digital transformation of nursing care.展开更多
基金Supported by clinical TCM scientific research project of Health and Family Plan-ning Commission of Anhui Province:2016ZY82~~
文摘Objective： To observe the difference in clinical efficacy between governor vessel-unblocking and mind- regulating acupuncture therapy combined with conventional rehabilitation therapy and simply conventional rehabilitation therapy for sensory and motor dysfunction of patients with spinal cord injury. Methods： Forty patients with spinal cord injury （SCI） were randomly assigned into rehabilitation combined with acupuncture group （group A） and rehabilitation group （group B）, with 20 patients in each group. In group A, governor vessel-unblocking and mind-regulating acupuncture therapy combined with conventional rehabilitation therapy was adopted, and Baihui（百会 GV 20）, Fengffu （风府GV 16）, Dazhui （大椎GV 14）, Zhiyang （至阳GV 9）, Mingmen （命门 GV 4） and Yfioyangguan （腰阳关 GV 3） were adopted as the main acupoints. Conventional rehabilitation therapy was also applied, including the rehabilitation training of joint, motion, respiration, urinary bladder and intestinal tract. In group B, conventional rehabilitation therapy was adopted as same as the group A. Treatment in the two groups was conducted for once a day, 6 times a week, and 12 weeks in total. ASIA motor score （MS）, ASIA sensory score （SS） and activity of daily living （ADL） score of patients in the two groups were observed before and after the treatment. Results： Before treatment, the differences in MS, SS and ADL score of patients in the two groups were not statistically significant （all P 〉 0.05）, and the results were comparable. After treatment, MS, SS and ADL score of patients in the two groups were all higher than that before the treatment （all P 〈 0.05）, and MS, SS and ADL score of the patients in group A were all higher than that in group B （all P 〈 0.05）. Conclusion： The curative effect of governor vessel-unblocking and mind-regulating acupuncture therapy combined with conventional rehabilitation therapy was superior to that of simply conventional rehabilitation therapy in the treatment of sensory and motor dysfunction of the patients with SCI.
基金funded by the National Research and Development Project of Key Chronic Diseases(Grant No.2016YFC1300703)the Fujian Provincial Natural Science Foundation of China(Grant No.2021J011367 and No.2021J011353)+3 种基金the Medical Project of Xiamen Municipal Bureau of Science and Technology(Grant No.3502Z20214ZD1013)Xiamen Municipal Health Commission,Xiamen Municipal Bureau of Science and Technology(Grant No.3502Z20209005)Fujian Provincial Clinical Research Center for Brain Diseases(Grant No.2021FJSLCYX01)Xiamen Clinical Research Center for Neurological Diseases(Grant No.2021XMSLCYX01).
文摘Background Hypertension is widely acknowledged as a significant contributory factor to the heightened risk of intracranial aneurysm rupture.Nevertheless,the impact of hypertension management on the outcomes subsequent to aneurysmal subarachnoid haemorrhage(aSAH),particularly concerning the severity of aSAH,remains an underexplored area.Methods We conducted a retrospective analysis using data from a prospectively multicentre cohort of 4545 patients with aSAH in China.Premorbid hypertension status and the utilisation of antihypertensive medications prior to admission were set as key exposure factors.The primary outcomes encompassed unfavourable clinical grading scales observed on admission.Employing multivariable logistic regression,we explored the association between premorbid hypertension status,preadmission use of renin-angiotensin aldosterone system(RAAS)inhibitors and unfavourable clinical grading scales.Results In comparison to patients with normal blood pressure,only uncontrolled hypertension demonstrated a significant and independent association with an elevated risk of poor outcomes on the Hunt-Hess scale(OR=1.799,95%CI 1.413 to 2.291,p<0.001)and the World Federation of Neurological Surgeons(WFNS)scale(OR=1.721,95%CI 1.425 to 2.079,p<0.001).Furthermore,the antecedent use of RAAS inhibitors before admission was markedly and independently linked to a diminished risk of adverse outcomes on the Hunt-Hess scale(OR=0.653,95%CI 0.430 to 0.992,p=0.046)and the WFNS scale(OR=0.656,95%CI 0.469 to 0.918,p=0.014).Conclusions Uncontrolled hypertension markedly elevates the risk of adverse clinical outcomes following an aSAH.Conversely,the preadmission utilisation of RAAS inhibitors demonstrates a noteworthy association with a favourable clinical outcome after aSAH.
文摘Objectives This study aimed to design and evaluate a detection system for the accidental dislodgement of head-and-neck medical supplies through hand position recognition and tracking in Intensive Care Unit(ICU)patients.Methods We conducted a single-center,prospective,parallel-group feasibility randomized controlled trial.We recruited 80 participants using convenience sampling from the ICU of a hospital in Ningbo City,Zhejiang Province,between March 2025 and June 2025,and they were randomly assigned to either the control group(routine care)or the intervention group(routine care plus image recognition-based detection system).The system continuously tracked patients’hand positions via bedside cameras and generated real-time alarms when hands entered predefined risk zones,notifying on-duty nurses to enable early intervention.System stability was assessed by continuous system uptime;system performance and clinical feasibility were evaluated by the frequencies of risk actions and accidental dislodgement of medical supplies(ADMS).Results All 80 participants completed the intervention,with 40 patients in each group.The baseline characteristics and median observation time of the two groups were balanced(intervention group:48 h/patient vs.control group:49 h/patient).Compared with the control group,the intervention group showed fewer ADMS(2/40 vs.9/40)and detected more risk actions per 100 h(36 vs.25);all system-detected events had corroborating images with complete concordance on manual review,and all nurse-recorded hand-contact events were accurately captured.Conclusions The study demonstrated that the image recognition-based detection system can function stably in clinical settings,providing accurate and continuous surveillance while supporting the early detection of risk actions.By reducing the observation burden and offering real-time cognitive support,the system complements routine nursing care and serves as an additional safety measure in ICU practice.With further optimization and larger multicenter validation,this approach could have the potential to make a significant contribution to the development of smart ICUs and the broader digital transformation of nursing care.
