To the Editor:Congenital heart diseases (CHDs)are the most common congenital structural anomalies in China.Most of them are curable after birth.However,some defects progress during fetal period,thus resulting in high ...To the Editor:Congenital heart diseases (CHDs)are the most common congenital structural anomalies in China.Most of them are curable after birth.However,some defects progress during fetal period,thus resulting in high neonatal mortality and morbidity. Pulmonary atresia with intact ventricular septum (PA/IVS)during fetal period is partly associated with right ventricle (RV)hypoplasia and its consequent hemodynamic deterioration,which limits the possibility of biventricular (BV)repair after birth.The 1-year survival of PA/IVS live births is around 70%,but the rate of BV outcome is around 30%.[1]展开更多
To the Editor:The incidence of pulmonary atresia with intact ventricular septum(PA/IVS)is 1.9%in congential heart disease.The most serious manifestation is hypoplastic right heart syndrome(HRHS).HRHS and low birth wei...To the Editor:The incidence of pulmonary atresia with intact ventricular septum(PA/IVS)is 1.9%in congential heart disease.The most serious manifestation is hypoplastic right heart syndrome(HRHS).HRHS and low birth weight have been determined as the major risk factors of fetal death after birth.Fetal pulmonary valvuloplasty(FPV)could relieve obstruction of the right ventricular outflow tract,restore growth potential of right ventricle,and increase the chances of biventricular circulation.However,so far fewer than 70 HRHS cases have been reported at the International Fetal Cardiac Intervention Registry(http://www.ifcir.org/)and there is a lack of postnatal treatment experience.展开更多
基金grants from the National Natural Science Foundation of China (No.81770316) Qingdao Outstanding Health Professional Development Fund (2017).
文摘To the Editor:Congenital heart diseases (CHDs)are the most common congenital structural anomalies in China.Most of them are curable after birth.However,some defects progress during fetal period,thus resulting in high neonatal mortality and morbidity. Pulmonary atresia with intact ventricular septum (PA/IVS)during fetal period is partly associated with right ventricle (RV)hypoplasia and its consequent hemodynamic deterioration,which limits the possibility of biventricular (BV)repair after birth.The 1-year survival of PA/IVS live births is around 70%,but the rate of BV outcome is around 30%.[1]
基金grants from the National Natural Science Foundation of China(No.81770316)the Research Fund for the Taishan Scholars Project(2018).
文摘To the Editor:The incidence of pulmonary atresia with intact ventricular septum(PA/IVS)is 1.9%in congential heart disease.The most serious manifestation is hypoplastic right heart syndrome(HRHS).HRHS and low birth weight have been determined as the major risk factors of fetal death after birth.Fetal pulmonary valvuloplasty(FPV)could relieve obstruction of the right ventricular outflow tract,restore growth potential of right ventricle,and increase the chances of biventricular circulation.However,so far fewer than 70 HRHS cases have been reported at the International Fetal Cardiac Intervention Registry(http://www.ifcir.org/)and there is a lack of postnatal treatment experience.
