Background:Acupuncture therapy provides a complementary and alternative approach to treating major depressive disorder(MDD),but its efficacy and safety have still not been comprehensively assessed.Recently published s...Background:Acupuncture therapy provides a complementary and alternative approach to treating major depressive disorder(MDD),but its efficacy and safety have still not been comprehensively assessed.Recently published systematic reviews remain confusing and inconclusive.Objective:This systematic review evaluated the efficacy and safety of acupuncture therapy alone or combined with antidepressants for adult patients with mild and moderate MDD.Search strategy:Chinese Biomedical Literature Database,China National Knowledge Infrastructure Database,Wanfang Database,Chinese Science and Technology Journal Database,Pub Med,Embase,and Cochrane Library were searched from their inceptions to March 2025.Inclusion criteria:Randomized controlled trials that compared acupuncture therapy with antidepressants,or acupuncture therapy plus antidepressants with acupuncture therapy or antidepressants for adult patients with mild and moderate MDD were included.Data extraction and analysis:Five reviewers independently extracted data from original literature using a standardized form,and the data were verified by two reviewers to ensure accuracy.Statistical meta-analyses,publication bias analyses,and subgroup analyses were performed by using Review Manager 5.3 software.The Grading of Recommendations Assessment,Development,and Evaluation approach was used to assess the certainty of the evidence.Results:A total of 60 eligible studies including 4675 participants were included.Low-certainty evidence showed that compared with antidepressants,acupuncture therapy(standardized mean difference[SMD]=-0.57;95%confidence interval[CI]=[-0.87,-0.27];I^(2)=86%;P=0.006)or acupuncture therapy plus antidepressants(SMD=-1.00;95%CI=[-1.18,-0.81];I^(2)=77%;P<0.00001)may reduce the severity of depression at the end of treatment.Low-certainty evidence indicated that compared with acupuncture therapy alone,acupuncture therapy plus antidepressants slightly reduced the severity of depression at the end of treatment(SMD=-0.38;95%CI=[-0.61,-0.14];I^(2)=18%;P=0.002).Similar results were also found for acupuncture's relief of insomnia.The reported adverse effects of acupuncture therapy were mild and transient.For most of the subgroup analyses,acupuncture type,scale type,and the course of treatment did not show a significant relative effect.Conclusion:Acupuncture therapy may provide antidepressant effects and relieve insomnia with mild adverse effects for adult patients with mild and moderate MDD.But the certainty of evidence was very low.More high-quality,well designed,large-scale studies with long-term follow-up are needed in the future.展开更多
Clinical Practice Guideline on Acupuncture and Moxibustion:Migraine(WFAS 007.9-2023)is a clinical practice guideline officially released by the World Federation of Acupuncture-Moxibustion Societies(WFAS)on October 9,2...Clinical Practice Guideline on Acupuncture and Moxibustion:Migraine(WFAS 007.9-2023)is a clinical practice guideline officially released by the World Federation of Acupuncture-Moxibustion Societies(WFAS)on October 9,2023,and is the first international guideline on the treatment of migraine with acupuncture.This international standard was developed under the guidance of rigorous evidence-based methodology,and it contains guideline purpose,scope,applicable population,applicable settings,overview of acupuncture for migraine,guideline development process and recommendations.For promoting the understanding and application of this guideline,this article summarizes a total of 18 recommendations in order to assist clinical decisions for migraine with acupuncture.展开更多
This demo shows a time-based microblog research system which developed based on the time profile to estimate the query model,the document model and rank function for microblog search.The system exploits the time profi...This demo shows a time-based microblog research system which developed based on the time profile to estimate the query model,the document model and rank function for microblog search.The system exploits the time profile to boost the performance of microblog search.A brief description of the time-based query model,time-based document model and time-based similarity score is introduced.The index strategy for temporal microblog search is described.Using TREC 2011 and TREC 2012 microblog retrieval collection,the examples of microblog search results are demonstrated.展开更多
Lyrics retrieval is one of the frequently-used retrieval functions of search engines. However, diversified information requirements are neglected in the existing lyrics retrieval systems. A lyrics retrieval system nam...Lyrics retrieval is one of the frequently-used retrieval functions of search engines. However, diversified information requirements are neglected in the existing lyrics retrieval systems. A lyrics retrieval system named LRC Sousou, in which erroneous characters are corrected automatically, the mixed queries of Chinese words and Pinyin are supported, and English phonemes queries are also achieved effectively, is introduced in this paper. The technologies of natural language processing, information retrieval and machine learning algorithm are applied to our lyrics retrieval system which enhance the practicability and efficiency of lyrics search, and improve user experience.展开更多
The international standard“General Requirements for the Risk Control in the Safe Use of Acupuncture”drafted by the Institute of Acupuncture and Moxibustion of the China Academy of Chinese Medical Sciences has been o...The international standard“General Requirements for the Risk Control in the Safe Use of Acupuncture”drafted by the Institute of Acupuncture and Moxibustion of the China Academy of Chinese Medical Sciences has been officially released by the World Federation of Acupuncture-Moxibustion Societies(WFAS).As the first general international standard in the field of acupuncture safety standards,to avoid the repetition of common problems,this standard specifies the basic requirements for the safe use of acupuncture,defines terms with common characteristics that are easily confused in the field of acupuncture safety,clarifies the scope and level of acupuncture risks,sorts out the sources of acupuncture risks,and formulates control processes and control measures for acupuncture risks,and lays the foundation for the establishment of subsequent related standards for specific needles.To help the developers of standards related to the safe use of acupuncture needles to better understand and apply this standard,this paper provides an in-depth interpretation of the development process and content of this standard.At the same time,it analyses the terminology definition process of this standard,the current research status of acupuncture risk,the sources of different types of acupuncture risk,and corresponding control measures.This can provide a professional reference for the developers of subsequent related standards for specific needles and help promote the safe use of acupuncture techniques worldwide.展开更多
The international standard titled“Technical Benchmark of Acupuncture and Moxibustion—General Rules for Drafting”(WFAS006.1—2023)has been officially launched on the World Federation of Acupuncture-Moxibustion Socie...The international standard titled“Technical Benchmark of Acupuncture and Moxibustion—General Rules for Drafting”(WFAS006.1—2023)has been officially launched on the World Federation of Acupuncture-Moxibustion Societies(WFAS)official website,which was drafted by the Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences,and approved and released by WFAS.This standard filled the gap in the existing international standards concerning the general rules for acupuncture technical operations,resolved several common technical issues in this field,provided a model for the international transformation of technical benchmark of acupuncture and moxibustion,and provided a reference for researchers of subsequent standards in this series.This paper provides an in-depth analysis of the standard from 3 aspects,including the development process,the structural framework and content,the research characteristics,and application value,with the aim of assisting professionals worldwide in undertaking the drafting of the series of WFAS“Technical Benchmark of Acupuncture and Moxibustion”in better understanding and applying the standard,thereby enhancing the quality,practicability,operability,and international applicability of the series standards.展开更多
Large-scale and long-time-span nonequilibrium molecular dynamics simulations have been performed to determine the thermal conductivity of single-walled and double-walled carbon nanotubes(CNTs)using a machine learning ...Large-scale and long-time-span nonequilibrium molecular dynamics simulations have been performed to determine the thermal conductivity of single-walled and double-walled carbon nanotubes(CNTs)using a machine learning potential trained on atomic energies and forces from density functional theory calculations for sp^(2)-hybridized carbon.The size dependence of graphene and CNTs up to 1μm has been studied with 200000 atoms and simulation times up to 5 ns.The simulations reveal that thermal transport,whether ballistic,quasi-ballistic,or diffusive,is determined by the relationship between the sample length and the effective mean-free path(MFP).The system size has less effect on thermal conductivity when the sample length significantly exceeds the MFP.Radial tensile strain in CNTs causes the C-C bond length to increase in smaller-diameter CNTs,resulting in a phonon softening effect that subsequently reduces thermal conductivity.An analytical function is proposed to describe the relationship between phonon relaxation time and nanotube diameter.The thermal conductivity of the double-walled CNT is lower than that of an equivalent-size single-walled CNT.Phonon-phonon scattering,interlayer van der Waals interactions,and degenerate coupling of transverse acoustic modes are considered to contribute to the reduction in thermal transport.展开更多
基金supported by the National Natural Science Foundation of China(No.82474644)the National Key R&D Foundation of China(No.2017YFC1703600)+1 种基金the Shenzhen“Sanming Project”(No.202101007)the Shenzhen Science and Technology Program(No.JCYJ2022081810080300)。
文摘Background:Acupuncture therapy provides a complementary and alternative approach to treating major depressive disorder(MDD),but its efficacy and safety have still not been comprehensively assessed.Recently published systematic reviews remain confusing and inconclusive.Objective:This systematic review evaluated the efficacy and safety of acupuncture therapy alone or combined with antidepressants for adult patients with mild and moderate MDD.Search strategy:Chinese Biomedical Literature Database,China National Knowledge Infrastructure Database,Wanfang Database,Chinese Science and Technology Journal Database,Pub Med,Embase,and Cochrane Library were searched from their inceptions to March 2025.Inclusion criteria:Randomized controlled trials that compared acupuncture therapy with antidepressants,or acupuncture therapy plus antidepressants with acupuncture therapy or antidepressants for adult patients with mild and moderate MDD were included.Data extraction and analysis:Five reviewers independently extracted data from original literature using a standardized form,and the data were verified by two reviewers to ensure accuracy.Statistical meta-analyses,publication bias analyses,and subgroup analyses were performed by using Review Manager 5.3 software.The Grading of Recommendations Assessment,Development,and Evaluation approach was used to assess the certainty of the evidence.Results:A total of 60 eligible studies including 4675 participants were included.Low-certainty evidence showed that compared with antidepressants,acupuncture therapy(standardized mean difference[SMD]=-0.57;95%confidence interval[CI]=[-0.87,-0.27];I^(2)=86%;P=0.006)or acupuncture therapy plus antidepressants(SMD=-1.00;95%CI=[-1.18,-0.81];I^(2)=77%;P<0.00001)may reduce the severity of depression at the end of treatment.Low-certainty evidence indicated that compared with acupuncture therapy alone,acupuncture therapy plus antidepressants slightly reduced the severity of depression at the end of treatment(SMD=-0.38;95%CI=[-0.61,-0.14];I^(2)=18%;P=0.002).Similar results were also found for acupuncture's relief of insomnia.The reported adverse effects of acupuncture therapy were mild and transient.For most of the subgroup analyses,acupuncture type,scale type,and the course of treatment did not show a significant relative effect.Conclusion:Acupuncture therapy may provide antidepressant effects and relieve insomnia with mild adverse effects for adult patients with mild and moderate MDD.But the certainty of evidence was very low.More high-quality,well designed,large-scale studies with long-term follow-up are needed in the future.
基金Supported by National Key Research and Development Program of China:2019YFC1712200,2019YFC1712203Independent Project of the Institute of Acupuncture and moxibustion,China Academy of Chinese Medical Sciences:ZZ202219004Science and technology innovation project of China Academy of Chinese Medical Sciences:CI2020A03510。
文摘Clinical Practice Guideline on Acupuncture and Moxibustion:Migraine(WFAS 007.9-2023)is a clinical practice guideline officially released by the World Federation of Acupuncture-Moxibustion Societies(WFAS)on October 9,2023,and is the first international guideline on the treatment of migraine with acupuncture.This international standard was developed under the guidance of rigorous evidence-based methodology,and it contains guideline purpose,scope,applicable population,applicable settings,overview of acupuncture for migraine,guideline development process and recommendations.For promoting the understanding and application of this guideline,this article summarizes a total of 18 recommendations in order to assist clinical decisions for migraine with acupuncture.
文摘This demo shows a time-based microblog research system which developed based on the time profile to estimate the query model,the document model and rank function for microblog search.The system exploits the time profile to boost the performance of microblog search.A brief description of the time-based query model,time-based document model and time-based similarity score is introduced.The index strategy for temporal microblog search is described.Using TREC 2011 and TREC 2012 microblog retrieval collection,the examples of microblog search results are demonstrated.
文摘Lyrics retrieval is one of the frequently-used retrieval functions of search engines. However, diversified information requirements are neglected in the existing lyrics retrieval systems. A lyrics retrieval system named LRC Sousou, in which erroneous characters are corrected automatically, the mixed queries of Chinese words and Pinyin are supported, and English phonemes queries are also achieved effectively, is introduced in this paper. The technologies of natural language processing, information retrieval and machine learning algorithm are applied to our lyrics retrieval system which enhance the practicability and efficiency of lyrics search, and improve user experience.
基金Independent project of the Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences,titled“Research on the International Standard Transformation of Acupuncture”(Project No.zz20242220)The National Key Research and Development Program of China(Project No.2019YFC1712202).
文摘The international standard“General Requirements for the Risk Control in the Safe Use of Acupuncture”drafted by the Institute of Acupuncture and Moxibustion of the China Academy of Chinese Medical Sciences has been officially released by the World Federation of Acupuncture-Moxibustion Societies(WFAS).As the first general international standard in the field of acupuncture safety standards,to avoid the repetition of common problems,this standard specifies the basic requirements for the safe use of acupuncture,defines terms with common characteristics that are easily confused in the field of acupuncture safety,clarifies the scope and level of acupuncture risks,sorts out the sources of acupuncture risks,and formulates control processes and control measures for acupuncture risks,and lays the foundation for the establishment of subsequent related standards for specific needles.To help the developers of standards related to the safe use of acupuncture needles to better understand and apply this standard,this paper provides an in-depth interpretation of the development process and content of this standard.At the same time,it analyses the terminology definition process of this standard,the current research status of acupuncture risk,the sources of different types of acupuncture risk,and corresponding control measures.This can provide a professional reference for the developers of subsequent related standards for specific needles and help promote the safe use of acupuncture techniques worldwide.
基金Independent project of the Institute of Acupuncture and MoxibustionChina Academy of Chinese Medical Sciences+2 种基金titled "Research on the International Standard Transformation of Acupuncture"(Project No. zz20242220)The National Key Research and Development Program of China (Project No. 2019YFC1712202)supported by the National Key Research and Development Program of the Ministry of Science and Technology of the People’s Republic of China.
文摘The international standard titled“Technical Benchmark of Acupuncture and Moxibustion—General Rules for Drafting”(WFAS006.1—2023)has been officially launched on the World Federation of Acupuncture-Moxibustion Societies(WFAS)official website,which was drafted by the Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences,and approved and released by WFAS.This standard filled the gap in the existing international standards concerning the general rules for acupuncture technical operations,resolved several common technical issues in this field,provided a model for the international transformation of technical benchmark of acupuncture and moxibustion,and provided a reference for researchers of subsequent standards in this series.This paper provides an in-depth analysis of the standard from 3 aspects,including the development process,the structural framework and content,the research characteristics,and application value,with the aim of assisting professionals worldwide in undertaking the drafting of the series of WFAS“Technical Benchmark of Acupuncture and Moxibustion”in better understanding and applying the standard,thereby enhancing the quality,practicability,operability,and international applicability of the series standards.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11504153 and 12002325)。
文摘Large-scale and long-time-span nonequilibrium molecular dynamics simulations have been performed to determine the thermal conductivity of single-walled and double-walled carbon nanotubes(CNTs)using a machine learning potential trained on atomic energies and forces from density functional theory calculations for sp^(2)-hybridized carbon.The size dependence of graphene and CNTs up to 1μm has been studied with 200000 atoms and simulation times up to 5 ns.The simulations reveal that thermal transport,whether ballistic,quasi-ballistic,or diffusive,is determined by the relationship between the sample length and the effective mean-free path(MFP).The system size has less effect on thermal conductivity when the sample length significantly exceeds the MFP.Radial tensile strain in CNTs causes the C-C bond length to increase in smaller-diameter CNTs,resulting in a phonon softening effect that subsequently reduces thermal conductivity.An analytical function is proposed to describe the relationship between phonon relaxation time and nanotube diameter.The thermal conductivity of the double-walled CNT is lower than that of an equivalent-size single-walled CNT.Phonon-phonon scattering,interlayer van der Waals interactions,and degenerate coupling of transverse acoustic modes are considered to contribute to the reduction in thermal transport.
