Heavy metal contamination of soil is one of the major challenges to sustainable agriculture.This contamination can be transmitted through the soil food chain and poses a serious threat to human health.In this study,we...Heavy metal contamination of soil is one of the major challenges to sustainable agriculture.This contamination can be transmitted through the soil food chain and poses a serious threat to human health.In this study,we found that freeze-thaw leaching(FTL)effectively complements the low removal rate of chemical leaching,and investigated the effects of different numbers of FTL on Cd contamination,soil chemical properties and microbial communities.The results showed that repeated FTL significantly reduced(P<0.05)the total Cd content in the top soil(19.02%-49.35%)and subsoil(0.41%-21.13%)and promoted the transformation of Cd to a more stable form,mainly through various removal mechanisms such as complexation,ion-exchange,and chemical precipitation.This finding was supported by reductions in several soil properties,including pH,available potassium(AK),and available phosphorus(AP).FTL treatment initially increased the bioavailability of Cd compared to chemical leaching,but bioavailability of Cd progressively decreased as the number of freeze-thaw cycles increased.Additionally,FTL reduced the richness and diversity of bacteria communities,destabilized ecological symbiotic networks,while increasing the richness and diversity of fungi in the soil.Various model analyses indicated that FTL treatment,available Cd,soil pH,AP and AK were the key drivers influencing the changes in microbial community structure.This study provides new insights and scientific bases for the effective management of heavy metal pollution in agricultural soils,the restoration of ecosystem health,and the improvement of soil sustainability.展开更多
Objective To assess the feasibility of internal suspension technique in retroperitoneal robot-assisted laparoscopic partial nephrectomy(rRAPN)with a new robotic platform called KangDuo Surgical Robot-01(KD-SR-01)syste...Objective To assess the feasibility of internal suspension technique in retroperitoneal robot-assisted laparoscopic partial nephrectomy(rRAPN)with a new robotic platform called KangDuo Surgical Robot-01(KD-SR-01)system(Suzhou KangDuo Robot Co.,Ltd.,Suzhou,China)and discuss its surgical technique.Methods A 44-year-old male patient was admitted with a 2.5 cm tumor on dorsolateral upper pole of the left kidney.The R.E.N.A.L.nephrometry score of this patient was 4x.This patient underwent rRAPN with KD-SR-01.The perinephric fat between the tumor and Gerota's fascia was preserved,which was used for internal suspension traction during tumor resection.Postoperative follow-up data were collected.Results The surgery was successfully carried out with a duration of 127 min,in which the docking time was 6 min 25 s and console time was 60 min.The warm ischemia time was 19 min 53 s,and the estimated blood loss was 0 mL.The pathological histology showed a pathological tumor stage 1a clear cell renal cell carcinoma,with a negative surgical margin.The World Health Organization/International Society of Urological Pathology(WHO/ISUP)grade of this patient was Grade 2.No recurrence was observed during the 6-month follow-up.Conclusion Internal suspension in rRAPN is feasible and effective with use of the new robotic system KD-SR-01.展开更多
Background:The KangDuo-Surgical Robot-01(KD-SR-01)system is a new surgical robot recently developed in China.The aim of this study was to present our single-center experience and mid-term outcomes of urological proced...Background:The KangDuo-Surgical Robot-01(KD-SR-01)system is a new surgical robot recently developed in China.The aim of this study was to present our single-center experience and mid-term outcomes of urological procedures using the KD-SR-01 system.Methods:From August 2020 to April 2023,consecutive urologic procedures were performed at Peking University First Hospital using the KD-SR-01 system.The clinical features,perioperative data,and follow-up outcomes were prospectively collected and analyzed.Results:A total of 110 consecutive patients were recruited.Among these patients,28 underwent partial nephrectomy(PN),41 underwent urinary tract reconstruction(26 underwent pyeloplasty,3 underwent ureteral reconstruction and 12 underwent ureterovesical reimplantation[UR]),and 41 underwent radical prostatectomy(RP).The median operative time for PN was 112.5 min,157.0 min for pyeloplasty,151.0 min for ureteral reconstruction,142.5 min for UR,and 138.0 min for RP.The median intraoperative blood loss was 10 mL for PN,10 mL for pyeloplasty,30 mL for ureteral reconstruction,20 mL for UR,and 50 mL for RP.All procedures were successfully completed without conversion,and there were no major complications in any patient.The median warm ischemia time of PN was 17.3 min,and positive surgical margin was not noted in any patient.The overall positive surgical margin rate of RP was 39%(16/41),and no biochemical recurrence was observed in any RP patient during the median follow-up of 11.0 months.The surgical success rates of pyeloplasty and UR were 96%(25/26)and 92%(11/12)during the median follow-up of 29.5 months and 11.5 months,respectively.Conclusion:The KD-SR-01 system appears feasible,safe,and effective for most urological procedures,based on our single-center experience.展开更多
To the Editor:Renal cell carcinoma is the most common cancer of the genitourinary tract and leads to over 170,000 deaths annually worldwide.For localized tumors,robot-assisted partial nephrectomy(RAPN)has emerged as a...To the Editor:Renal cell carcinoma is the most common cancer of the genitourinary tract and leads to over 170,000 deaths annually worldwide.For localized tumors,robot-assisted partial nephrectomy(RAPN)has emerged as a popular option due to its numerous benefits,including better ergonomics,better functional outcomes,similar oncological outcomes,and minimal invasiveness.The KangDuo surgical robot(KD-SR),a novel robotic surgical platform,was developed by SuZhou KangDuo Robot Co.,Ltd.(Suzhou,China).Recently,we reported that the KD-SR achieved noninferior outcomes compared to the da Vinci Si Surgical System(DV-SS-Si)in terms of surgical success for T1a tumors.[1]However,the oncological outcomes of the KD-SR and the DV-SS-Si are yet to be compared.In this prospective randomized cohort trial,we aimed to compare the patient-reported health-related quality of life(HRQoL)and medium-term oncological outcomes of the KD-SR vs.the DV-SS-Si for RAPN.展开更多
基金supported by the National Natural Science Foundation of China(No.42077135).
文摘Heavy metal contamination of soil is one of the major challenges to sustainable agriculture.This contamination can be transmitted through the soil food chain and poses a serious threat to human health.In this study,we found that freeze-thaw leaching(FTL)effectively complements the low removal rate of chemical leaching,and investigated the effects of different numbers of FTL on Cd contamination,soil chemical properties and microbial communities.The results showed that repeated FTL significantly reduced(P<0.05)the total Cd content in the top soil(19.02%-49.35%)and subsoil(0.41%-21.13%)and promoted the transformation of Cd to a more stable form,mainly through various removal mechanisms such as complexation,ion-exchange,and chemical precipitation.This finding was supported by reductions in several soil properties,including pH,available potassium(AK),and available phosphorus(AP).FTL treatment initially increased the bioavailability of Cd compared to chemical leaching,but bioavailability of Cd progressively decreased as the number of freeze-thaw cycles increased.Additionally,FTL reduced the richness and diversity of bacteria communities,destabilized ecological symbiotic networks,while increasing the richness and diversity of fungi in the soil.Various model analyses indicated that FTL treatment,available Cd,soil pH,AP and AK were the key drivers influencing the changes in microbial community structure.This study provides new insights and scientific bases for the effective management of heavy metal pollution in agricultural soils,the restoration of ecosystem health,and the improvement of soil sustainability.
文摘Objective To assess the feasibility of internal suspension technique in retroperitoneal robot-assisted laparoscopic partial nephrectomy(rRAPN)with a new robotic platform called KangDuo Surgical Robot-01(KD-SR-01)system(Suzhou KangDuo Robot Co.,Ltd.,Suzhou,China)and discuss its surgical technique.Methods A 44-year-old male patient was admitted with a 2.5 cm tumor on dorsolateral upper pole of the left kidney.The R.E.N.A.L.nephrometry score of this patient was 4x.This patient underwent rRAPN with KD-SR-01.The perinephric fat between the tumor and Gerota's fascia was preserved,which was used for internal suspension traction during tumor resection.Postoperative follow-up data were collected.Results The surgery was successfully carried out with a duration of 127 min,in which the docking time was 6 min 25 s and console time was 60 min.The warm ischemia time was 19 min 53 s,and the estimated blood loss was 0 mL.The pathological histology showed a pathological tumor stage 1a clear cell renal cell carcinoma,with a negative surgical margin.The World Health Organization/International Society of Urological Pathology(WHO/ISUP)grade of this patient was Grade 2.No recurrence was observed during the 6-month follow-up.Conclusion Internal suspension in rRAPN is feasible and effective with use of the new robotic system KD-SR-01.
文摘Background:The KangDuo-Surgical Robot-01(KD-SR-01)system is a new surgical robot recently developed in China.The aim of this study was to present our single-center experience and mid-term outcomes of urological procedures using the KD-SR-01 system.Methods:From August 2020 to April 2023,consecutive urologic procedures were performed at Peking University First Hospital using the KD-SR-01 system.The clinical features,perioperative data,and follow-up outcomes were prospectively collected and analyzed.Results:A total of 110 consecutive patients were recruited.Among these patients,28 underwent partial nephrectomy(PN),41 underwent urinary tract reconstruction(26 underwent pyeloplasty,3 underwent ureteral reconstruction and 12 underwent ureterovesical reimplantation[UR]),and 41 underwent radical prostatectomy(RP).The median operative time for PN was 112.5 min,157.0 min for pyeloplasty,151.0 min for ureteral reconstruction,142.5 min for UR,and 138.0 min for RP.The median intraoperative blood loss was 10 mL for PN,10 mL for pyeloplasty,30 mL for ureteral reconstruction,20 mL for UR,and 50 mL for RP.All procedures were successfully completed without conversion,and there were no major complications in any patient.The median warm ischemia time of PN was 17.3 min,and positive surgical margin was not noted in any patient.The overall positive surgical margin rate of RP was 39%(16/41),and no biochemical recurrence was observed in any RP patient during the median follow-up of 11.0 months.The surgical success rates of pyeloplasty and UR were 96%(25/26)and 92%(11/12)during the median follow-up of 29.5 months and 11.5 months,respectively.Conclusion:The KD-SR-01 system appears feasible,safe,and effective for most urological procedures,based on our single-center experience.
文摘To the Editor:Renal cell carcinoma is the most common cancer of the genitourinary tract and leads to over 170,000 deaths annually worldwide.For localized tumors,robot-assisted partial nephrectomy(RAPN)has emerged as a popular option due to its numerous benefits,including better ergonomics,better functional outcomes,similar oncological outcomes,and minimal invasiveness.The KangDuo surgical robot(KD-SR),a novel robotic surgical platform,was developed by SuZhou KangDuo Robot Co.,Ltd.(Suzhou,China).Recently,we reported that the KD-SR achieved noninferior outcomes compared to the da Vinci Si Surgical System(DV-SS-Si)in terms of surgical success for T1a tumors.[1]However,the oncological outcomes of the KD-SR and the DV-SS-Si are yet to be compared.In this prospective randomized cohort trial,we aimed to compare the patient-reported health-related quality of life(HRQoL)and medium-term oncological outcomes of the KD-SR vs.the DV-SS-Si for RAPN.
