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Maize tasseling date forecast from canopy height time series estimated by UAV LiDAR data
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作者 Yadong liu Chenwei Nie +11 位作者 Liang Li Lei Shi shuaibing liu Fei Nan Minghan Cheng Xun Yu Yi Bai Xiao Jia Liming Li Yali Bai Dameng Yin Xiuliang Jin 《The Crop Journal》 2025年第3期975-990,共16页
Timely identification and forecast of maize tasseling date(TD)are very important for agronomic management,yield prediction,and crop phenotype estimation.Remote sensing-based phenology monitoring has mostly relied on t... Timely identification and forecast of maize tasseling date(TD)are very important for agronomic management,yield prediction,and crop phenotype estimation.Remote sensing-based phenology monitoring has mostly relied on time series spectral index data of the complete growth season.A recent development in maize phenology detection research is to use canopy height(CH)data instead of spectral indices,but its robustness in multiple treatments and stages has not been confirmed.Meanwhile,because data of a complete growth season are needed,the need for timely in-season TD identification remains unmet.This study proposed an approach to timely identify and forecast the maize TD.We obtained RGB and light detection and ranging(Li DAR)data using the unmanned aerial vehicle platform over plots of different maize varieties under multiple treatments.After CH estimation,the feature points(inflection point)from the Logistic curve of the CH time series were extracted as TD.We examined the impact of various independent variables(day of year vs.accumulated growing degree days(AGDD)),sensors(RGB and Li DAR),time series denoise methods,different feature points,and temporal resolution on TD identification.Lastly,we used early CH time series data to predict height growth and further forecast TD.The results showed that using the 99th percentile of plot scale digital surface model and the minimum digital terrain model from Li DAR to estimate maize CH was the most stable across treatments and stages(R~2:0.928 to0.943).For TD identification,the best performance was achieved by using Li DAR data with AGDD as the independent variable,combined with the knee point method,resulting in RMSE of 2.95 d.The high accuracy was maintained at temporal resolutions as coarse as 14 d.TD forecast got more accurate as the CH time series extended.The optimal timing for forecasting TD was when the CH exceeded half of its maximum.Using only Li DAR CH data below 1.6 m and empirical growth rate estimates,the forecasted TD showed an RMSE of 3.90 d.In conclusion,this study exploited the growth characteristics of maize height to provide a practical approach for the timely identification and forecast of maize TD. 展开更多
关键词 MAIZE Phenology forecast Canopy height time series UAV LiDAR Logistic curve
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Evaluation of exposure-response-safety relationship of model-informed low-dose 500 mg abiraterone acetate inprostate cancer patients
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作者 Edmund Chiong Ziteng Wang +13 位作者 Eleanor Jing Yi Cheong Yi Chen Yao Sin Mun Tham Revathi Periaswami Poh Choo Toh Ziting Wang Qing Hui Wu Woon Chau Tsang Arshvin Kesavan Alvin Seng Cheong Wong Patrick Thomas Wong Felicia Lim shuaibing liu Eric Chun Yong Chan 《Cancer Communications》 2025年第8期971-975,共5页
Prostate cancer is a common cancer among men world-wide.Large-scale clinicalstudies of the 1,000 mg daily dos-ing of abiraterone acetate(AA)have confirmed its antitu-mor efficacy in patients with metastatic hormone-se... Prostate cancer is a common cancer among men world-wide.Large-scale clinicalstudies of the 1,000 mg daily dos-ing of abiraterone acetate(AA)have confirmed its antitu-mor efficacy in patients with metastatic hormone-sensitiveprostate cancer(mHSPC)or metastatic castration-resistantprostate cancer(mCRPC),regardless of their cancer’sresponse to androgen deprivation therapy(ADT)or treat-ment duration.However,this dosage was indirectly jus-tified based on the absence of dose-limiting toxicities(DLTs)in prior phase I dose-escalation trials,where aplateau in the increase of upstream steroids relating tosecondary mineralocorticoid excess was observed at dosesgreater than 750 mg and up to 2,000 mg daily[1,2].Notably,prostate specific antigen(PSA)levels declined atall investigated doses(250 to 1,000 mg)[1,2]. 展开更多
关键词 androgen deprivation therapy adt prostate cancer abiraterone acetate aa SAFETY model informed low dose exposure response abiraterone acetate
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