Dear Editor, Patients of bilateral pediatric testicular tumors and bilateral testicular teratoma or yolk sac tumor (YST) were rarely reported, and there was still no standard therapy. However, synchronous bilateral te...Dear Editor, Patients of bilateral pediatric testicular tumors and bilateral testicular teratoma or yolk sac tumor (YST) were rarely reported, and there was still no standard therapy. However, synchronous bilateral testicular tumors with different histology were a quite rare situation. We reported the first case of successful radical orchiectomy in the left scrotum and testicular sparing surgery in the right testis sequentially. No atrophy or residual tumor in the right testis and no recurrence in the left scrotum were found after 7 years of follow-up. Ethical approval was obtained from the Institutional Review Board of Childrens Hospital of Shanghai, which was affiliated to the Shanghai Jiao Tong University, School of Medicine, Shanghai, China. Informed consent was obtained from his parents.展开更多
The aim of this study was to investigate the trend in testicular volume changes after orchiopexy in children with cryptorchidism.The clinical data of 854 children with cryptorchidism who underwent orchiopexy between J...The aim of this study was to investigate the trend in testicular volume changes after orchiopexy in children with cryptorchidism.The clinical data of 854 children with cryptorchidism who underwent orchiopexy between January 2013 and December 2016 in Shenzhen Children’s Hospital(Shenzhen,China)were retrospectively analyzed.The mean(standard deviation)age of the patients was 2.8(2.5)years,and the duration of follow-up ranged from 1 year to 5 years.Ultrasonography was conducted preoperatively and postoperatively.The variables analyzed included age at the time of surgery,type of surgical procedure,laterality,preoperative testicular position,preoperative and postoperative testicular volumes,and the testicular volume ratio of them.The average testicular volumes preoperatively and at 1 year,2 years,3 years,and 5 years postoperatively were 0.27 ml,0.38 ml,0.53 ml,0.87 ml,and 1.00 ml,respectively(P<0.001).The corresponding testicular volume ratios were 0.67,0.76,0.80,0.83,and 0.84(P<0.001).The mean volume of the undescended testes was significantly smaller than the mean normative value(P<0.001,lower than the 10th percentile).The postoperative testicular volumes in children with cryptorchidism were generally lower than those in healthy boys but were still greater than the 10th percentile and exhibited an increasing trend.The older the child is at the time of surgery,the larger the gap in volume between the affected and normal testes.Although testicular volume tends to gradually increase after orchiopexy for cryptorchidism,it could not normalizes.Earlier surgery results in affected testicular volumes closer to those of healthy boys.展开更多
文摘Dear Editor, Patients of bilateral pediatric testicular tumors and bilateral testicular teratoma or yolk sac tumor (YST) were rarely reported, and there was still no standard therapy. However, synchronous bilateral testicular tumors with different histology were a quite rare situation. We reported the first case of successful radical orchiectomy in the left scrotum and testicular sparing surgery in the right testis sequentially. No atrophy or residual tumor in the right testis and no recurrence in the left scrotum were found after 7 years of follow-up. Ethical approval was obtained from the Institutional Review Board of Childrens Hospital of Shanghai, which was affiliated to the Shanghai Jiao Tong University, School of Medicine, Shanghai, China. Informed consent was obtained from his parents.
基金This study was funded by the Guangdong High-level Hospital Construction Fund and Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties(SZXK035).
文摘The aim of this study was to investigate the trend in testicular volume changes after orchiopexy in children with cryptorchidism.The clinical data of 854 children with cryptorchidism who underwent orchiopexy between January 2013 and December 2016 in Shenzhen Children’s Hospital(Shenzhen,China)were retrospectively analyzed.The mean(standard deviation)age of the patients was 2.8(2.5)years,and the duration of follow-up ranged from 1 year to 5 years.Ultrasonography was conducted preoperatively and postoperatively.The variables analyzed included age at the time of surgery,type of surgical procedure,laterality,preoperative testicular position,preoperative and postoperative testicular volumes,and the testicular volume ratio of them.The average testicular volumes preoperatively and at 1 year,2 years,3 years,and 5 years postoperatively were 0.27 ml,0.38 ml,0.53 ml,0.87 ml,and 1.00 ml,respectively(P<0.001).The corresponding testicular volume ratios were 0.67,0.76,0.80,0.83,and 0.84(P<0.001).The mean volume of the undescended testes was significantly smaller than the mean normative value(P<0.001,lower than the 10th percentile).The postoperative testicular volumes in children with cryptorchidism were generally lower than those in healthy boys but were still greater than the 10th percentile and exhibited an increasing trend.The older the child is at the time of surgery,the larger the gap in volume between the affected and normal testes.Although testicular volume tends to gradually increase after orchiopexy for cryptorchidism,it could not normalizes.Earlier surgery results in affected testicular volumes closer to those of healthy boys.