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BNCT中子源的研发现况与展望 被引量:8
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作者 傅世年 梁天骄 陈和生 《科学通报》 EI CAS CSCD 北大核心 2022年第14期1471-1478,共8页
硼中子俘获疗法(boron neutron capture therapy,BNCT)治疗癌症是一种典型的二元疗法,它既需要高品质的中子束,又需要高靶向性的含硼药物,两者缺一不可、密切配合,方可对肿瘤实现细胞级精准的靶向杀伤.BNCT治疗方法显著的优越性的背后,... 硼中子俘获疗法(boron neutron capture therapy,BNCT)治疗癌症是一种典型的二元疗法,它既需要高品质的中子束,又需要高靶向性的含硼药物,两者缺一不可、密切配合,方可对肿瘤实现细胞级精准的靶向杀伤.BNCT治疗方法显著的优越性的背后,是对中子源和载硼药物特性的很高要求.含硼药物研究涉及多学科,包括放射学、化学、医学、药学、生物学和物理学等.本文主要讨论BNCT中子源的问题.首先,介绍BNCT对中子束特性要求的国际标准,回顾几十年来BNCT中子源发展的困难所在;然后,展现近年来加速器中子源异军突起、开创BNCT新未来的前景,明确研发中的核心技术;最后,报告我国在此领域前沿研究的最新成果及其发展展望. 展开更多
关键词 硼中子俘获疗法(BNCT) 强流质子加速器 中子源 载硼靶向药物
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Study on the fringe field effect of quadrupoles for CSNS MEBT
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作者 Xibao Luo Jun Peng +1 位作者 shinian fu Sheng Wang 《Radiation Detection Technology and Methods》 CSCD 2023年第1期134-138,共5页
Background Medium energy beam transport(MEBT)of the China Spallation Neutron Source matches the beam from RFQ to DTL.It is found in the beam commissioning that the fringe field effect of quadrupoles in MEBT has a grea... Background Medium energy beam transport(MEBT)of the China Spallation Neutron Source matches the beam from RFQ to DTL.It is found in the beam commissioning that the fringe field effect of quadrupoles in MEBT has a great influence on matching.Purpose The aspect ratio of the quadrupoles is 1.67,which induces a strong fringing field effect,and the hard-edge model used in the design needs to be improved.Methods The slicing model was performed,and the accuracy of the quadrupole model was improved.Furthermore,to use the improved model online,based on the premise that the integral field of the quadrupole magnet remains unchanged,an equivalent transfer matrix was worked out to make the beam parameters consistent with the slicing model in the simulation.Results and conclusions In the machine study,with the new model,the beam parameters at the RFQ exit were measured,which is much closer to the RFQ design value.The MEBT lattice was redesigned based on the equivalent transfer matrix.With the new matched MEBT,the transmission rate of DTL reached 99.5%in the beam commissioning,which is increased by a factor of 3%. 展开更多
关键词 CSNS MEBT Fringe field effect Beam matching
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