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630nm激光联合血卟啉衍生物治疗晚期支气管肺癌的近期临床疗效分析
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作者 李林宇 崔世超 +2 位作者 杨晓晖 曹艺巍 林存智 《中华临床医师杂志(电子版)》 CAS 2024年第2期133-138,共6页
目的探讨630 nm激光联合血卟啉衍生物治疗晚期支气管肺癌的近期临床疗效及安全性。方法选择青岛大学附属医院2019年3月至2023年9月经病理确诊的43例晚期支气管肺癌患者,行支气管肺癌介入治疗后,联合630 nm激光和血卟啉衍生物及化疗、免... 目的探讨630 nm激光联合血卟啉衍生物治疗晚期支气管肺癌的近期临床疗效及安全性。方法选择青岛大学附属医院2019年3月至2023年9月经病理确诊的43例晚期支气管肺癌患者,行支气管肺癌介入治疗后,联合630 nm激光和血卟啉衍生物及化疗、免疫治疗。随访患者基本临床特征及治疗后的不良反应,治疗后1个月复查胸部CT及支气管镜检查。结果胸部CT显示治疗后气管或支气管内肿瘤体积较术前明显缩小,改善通气。支气管镜检查显示,治疗后肿瘤体积减小,甚至消失。治疗1个月后按时复查胸部CT及支气管镜检查的患者为31例(72.09%),31例患者的总有效率70.97%。43例患者均未出现严重并发症,但3例患者出现常见并发症。结论630 nm激光联合血卟啉衍生物治疗晚期支气管肺癌近期临床疗效明显,能改善气道狭窄,缓解呼吸困难、咳嗽等症状,安全性好,值得在临床推广应用。 展开更多
关键词 630nm激光 血叶啉衍生物 肺癌 光动力疗法 近期疗效
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Estimation of copper concentration of rocks using hyperspectral technology 被引量:2
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作者 shichao cui Kefa ZHOU Rufu DING 《Frontiers of Earth Science》 SCIE CAS CSCD 2019年第3期563-574,共12页
Rock geochemical information is important for mineral exploration and provides a theoretical basis for the rapid delineation of hidden minerals. Remote sensing technology provides the possibility of rapid and large-sc... Rock geochemical information is important for mineral exploration and provides a theoretical basis for the rapid delineation of hidden minerals. Remote sensing technology provides the possibility of rapid and large-scale extraction of geochemical information from the earth’s surface. This study analyzed the relationship between copper concentration and rock spectra by first collecting 222 rock samples, and then measuring the copper concentration of rock samples in the laboratory and reflectance spectra using an ASD FieldSpec3 portable spectrometer. It finally established quantitative relationships between the original spectra, first-order derivative spectra and second-order derivative spectra and copper concentration, respectively, using the partial least squares support vector machine method (PLS-SVM). The results show that 1) The estimation accuracy of using second-order derivatives spectra as input parameters to establish a model for estimating copper concentration is the highest, and the determined coefficient (R2) between the predicted value and real value reaches 0.54. 2) When the copper concentration is less than 80 mg/kg, the inversion model of copper concentration established using PLS-SVM obtains a good result. The R2 between the predicted copper concentration and the real copper concentration reached 0.70248. When the copper concentration is greater than 80 mg/kg, the inversion model of copper concentration established using partial least squares (PLS) obtains a good result. The R2 between the predicted copper concentration and the real copper concentration reached 0.49. The R2 between real copper concentration and copper predicted by the method of piecewise separate modeling reaches 0.816.Therefore, the method of segmental modeling has great potential to improve the accuracy of copper concentration inversion. 展开更多
关键词 COPPER CONCENTRATION ROCK GEOCHEMICAL information PLS-SVM remote sensing
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