The damping-controlled deployment technology of flexible Z-folded inflatable tube is one of the key technologies of space inflatable structures.Constraint failure between couple nodes is proposed to simulate the dampi...The damping-controlled deployment technology of flexible Z-folded inflatable tube is one of the key technologies of space inflatable structures.Constraint failure between couple nodes is proposed to simulate the damping-controlled deployment.And the equation of constraint failure is established.Inflation process of Z-folded tube is simulated with control volume method.Compared with uncontrolled method,it is indicated that the new method can effectively solve the disordered deployment problem of the slender Z-folded inflatable tube.By analyzing the displacement of the apical of the folded tube with different constraint forces during deployment process,the concept of effective constraint force is proposed.In the effective region of constraint force,the folded tube deploys with little retraction and fluctuation.Otherwise,The flexible folded tube would deploy disorderly or even cannot deploy.The simulation method and numerical results have a theoretical and instructive significance to the research on the space inflatable structures.展开更多
Objective To investigate the role and mechanism of(histone deacetylase 6,HDAC6)in the epithelial-mesenchymal transition(EMT)of renal tubular epithelial cells and the activation of renal interstitial fibroblasts.Method...Objective To investigate the role and mechanism of(histone deacetylase 6,HDAC6)in the epithelial-mesenchymal transition(EMT)of renal tubular epithelial cells and the activation of renal interstitial fibroblasts.Methods Human renal tubular epithelial cells(HK-2)and rat renal interstitial fibroblast(NRK-49F)were cultured in vitro,and divided into 4 groups:control group,Tubastatin A(TA)group(treated with 10μmol/L HDAC6 inhibitor TA for 36 h),transforming growth factor-β1(TGF-β1)group(10 ng/ml TGF-β1 for 36 h),and TGF-β1+TA group(treated with 10 ng/ml TGF-β1 and 10μmol/L TA for 36 h).展开更多
基金supported by the National Natural Science Foundation of China(No.11172137)the Fund of Aeronautics Science(No.20122910001)
文摘The damping-controlled deployment technology of flexible Z-folded inflatable tube is one of the key technologies of space inflatable structures.Constraint failure between couple nodes is proposed to simulate the damping-controlled deployment.And the equation of constraint failure is established.Inflation process of Z-folded tube is simulated with control volume method.Compared with uncontrolled method,it is indicated that the new method can effectively solve the disordered deployment problem of the slender Z-folded inflatable tube.By analyzing the displacement of the apical of the folded tube with different constraint forces during deployment process,the concept of effective constraint force is proposed.In the effective region of constraint force,the folded tube deploys with little retraction and fluctuation.Otherwise,The flexible folded tube would deploy disorderly or even cannot deploy.The simulation method and numerical results have a theoretical and instructive significance to the research on the space inflatable structures.
文摘Objective To investigate the role and mechanism of(histone deacetylase 6,HDAC6)in the epithelial-mesenchymal transition(EMT)of renal tubular epithelial cells and the activation of renal interstitial fibroblasts.Methods Human renal tubular epithelial cells(HK-2)and rat renal interstitial fibroblast(NRK-49F)were cultured in vitro,and divided into 4 groups:control group,Tubastatin A(TA)group(treated with 10μmol/L HDAC6 inhibitor TA for 36 h),transforming growth factor-β1(TGF-β1)group(10 ng/ml TGF-β1 for 36 h),and TGF-β1+TA group(treated with 10 ng/ml TGF-β1 and 10μmol/L TA for 36 h).
