Stroke,a major cerebrovascular disease,has high morbidity and mortality.Effective methods to reduce the risk and improve the prognosis are lacking.Currently,uric acid(UA)is associated with the pathological mechanism,p...Stroke,a major cerebrovascular disease,has high morbidity and mortality.Effective methods to reduce the risk and improve the prognosis are lacking.Currently,uric acid(UA)is associated with the pathological mechanism,prognosis,and therapy of stroke.UA plays pro/anti-oxidative and pro-inflammatory roles in vivo.The specific role of UA in stroke,which may have both neuroprotective and damaging effects,remains unclear.There is a U-shaped association between serum uric acid(SUA)levels and ischemic stroke(IS).UA therapy provides neuroprotection during reperfusion therapy for acute ischemic stroke(AIS).Urate-lowering therapy(ULT)plays a protective role in IS with hyperuricemia or gout.SUA levels are associated with the cerebrovascular injury mechanism,risk,and outcomes of hemorrhagic stroke.In this review,we summarize the current research on the role of UA in stroke,providing potential targets for its prediction and treatment.展开更多
Carbon materials are considered as prospective anode candidates for potassium ion batteries(PIBs).However,the low-rate capability is hampered by slow K+diffusion kinetics and obstructed electron transport of carbon-ba...Carbon materials are considered as prospective anode candidates for potassium ion batteries(PIBs).However,the low-rate capability is hampered by slow K+diffusion kinetics and obstructed electron transport of carbon-based anodes.In this work,calcium D-gluconate derived mesoporous carbon nanosheets(CGC)were interpenetrated into the architecture of reduced graphene oxides(RGO)to form the composites of two-dimensional(2D)/2D graphene/mesoporous carbon nanosheets(RGO@CGC).CGC as a rigid skeleton can prevent the graphene layers from restacking and maintain the structural stability of the 2D/2D carbon composites of RGO@CGC.The mesopores in CGC can shorten the path of ion diffusion and facilitate the penetration of electrolytes.RGO possesses the high surface-to-volume ratio and superior electron transport capability in the honeycomb-like 2D network consisting of sp^(2)-hybridized carbon atoms.Especially,theπ-πstacking interaction between CGC and RGO enhances stable composite structure formation,expedites interlayer-electron transfer,and establishes three-dimensional(3D)ion transportation pathways.Owing to these unique structure,RGO@CGC exhibits fast and stable potassium storage capability.Furthermore,the effects of binders and electrolytes on the electrochemical performance of RGO@CGC were investigated.Finally,Prussian blue was synthesized as a positive electrode to explore the possibility of RGO@CGC as a full battery application.展开更多
Direct air capture(DAC)is a negative carbon emission technology that faces challenges in scalability and practical deployment due to its exorbitant costs.Hou et al.(2017)integrated DAC technology with fertilization.A ...Direct air capture(DAC)is a negative carbon emission technology that faces challenges in scalability and practical deployment due to its exorbitant costs.Hou et al.(2017)integrated DAC technology with fertilization.A multi-bed desorption system driven by water provides a competitive and sustainable carbon source for indoor agriculture.展开更多
Bone has long been acknowledged as a fundamental structural entity that provides support and protection to the body’s organs.However,emerging research indicates that bone plays a crucial role in the regulation of sys...Bone has long been acknowledged as a fundamental structural entity that provides support and protection to the body’s organs.However,emerging research indicates that bone plays a crucial role in the regulation of systemic metabolism.This is achieved through the secretion of a variety of hormones,cytokines,metal ions,extracellular vesicles,and other proteins/peptides,collectively referred to as bone-derived factors(BDFs).BDFs act as a medium through which bones can exert targeted regulatory functions upon various organs,thereby underscoring the profound and concrete implications of bone in human physiology.Nevertheless,there remains a pressing need for further investigations to elucidate the underlying mechanisms that inform the effects of bone on other body systems.This review aims to summarize the current findings related to the roles of these significant modulators across different organs and metabolic contexts by regulating critical genes and signaling pathways in vivo.It also addresses their involvement in the pathogenesis of various diseases affecting the musculoskeletal system,circulatory system,glucose and lipid metabolism,central nervous system,urinary system,and reproductive system.The insights gained from this review may contribute to the development of innovative therapeutic strategies through a focused approach to bone secretomes.Continued research into BDFs is expected to enhance our understanding of bone as a multifunctional organ with diverse regulatory roles in human health.展开更多
Allopolyploids often exhibit advantages in vigor and adaptability compared to diploids.A long-term goal in the economically important Brassica genus has been to develop a new allohexaploid crop type(AABBCC)by combinin...Allopolyploids often exhibit advantages in vigor and adaptability compared to diploids.A long-term goal in the economically important Brassica genus has been to develop a new allohexaploid crop type(AABBCC)by combining different diploid and allotetraploid crop species.However,early-generation allohexaploids often face challenges like unstable meiosis and low fertility,and the phenotypic performance of these synthetic lines has rarely been assessed.This study analyzes agronomic traits,fertility,and genome stability in ArArBcBcCcCc lines derived from four crosses between B.carinata and B.rapa after 9–11 selfing generations.Our results demonstrate polyploid advantage in vigor and seed traits,considerable phenotypic variation,and high fertility and genome stability.Meanwhile,parental genotypes significantly influence outcomes in advanced allohexaploids.Structural variants,largely resulting from A–C homoeologous exchanges,contribute to genomic variation and influence hexaploid genome stability,with the A sub-genome showing the highest variability.Both positive and negative impacts of SVs on fertility and seed weight are observed.Pseudo-euploids,frequently appearing,do not significantly affect fertility or other agronomic traits compared to euploids,indicating a potential pathway toward a stable allohexaploid species.These findings provide insights into the challenge and potential for developing an adaptable and stable Brassica hexaploid through selection.展开更多
The Australian monsoon system plays a pivotal role in the tropical climate system by modulating the El Niño-Southern Oscillation(ENSO)development through multi-scale ocean-atmosphere interactions.This study ident...The Australian monsoon system plays a pivotal role in the tropical climate system by modulating the El Niño-Southern Oscillation(ENSO)development through multi-scale ocean-atmosphere interactions.This study identifies a significant decadal weakening of the Australian cross-equatorial flow intensity over the past two decades,attributed to the concurrent westward shift of the Australian High(AH)during austral winter.These decadal changes in the Australian monsoon reduce tropical Pacific atmospheric convection and the associated westerly wind anomalies over the centralto-western Pacific,which are crucial precursors for ENSO development.This process diminishes air-sea coupling feedback,including the thermocline feedback and the Ekman feedback,ultimately decreasing the strength of warm ENSO(El Niño)events.Using the Community Earth System Model,we confirm the close linkage between the Australian monsoon and ENSO on the decadal timescale.These findings provide new insights into the coupled relationship between ENSO and monsoon variability,offering a valuable framework for understanding ENSO’s longterm modulation and improving future climate predictions.展开更多
Background:Exercise elicits cardiometabolic benefits,reducing the risks of cardiovascular diseases and type 2 diabetes.This study aimed to investigate the vascular and metabolic effects of gut microbiota from exercise...Background:Exercise elicits cardiometabolic benefits,reducing the risks of cardiovascular diseases and type 2 diabetes.This study aimed to investigate the vascular and metabolic effects of gut microbiota from exercise-trained donors on sedentary mice with type 2 diabetes and the potential mechanism.Methods:Leptin receptor-deficient diabetic(db/db)and nondiabetic(db/m+)mice underwent running treadmill exercise for 8 weeks,during which fecal microbiota transplantation(FMT)was parallelly performed from exercise-trained to sedentary diabetic(db/db)mice.Endothelial function,glucose homeostasis,physical performance,and vascular signaling of recipient mice were assessed.Vascular and intestinal stresses,including inflammation,oxidative stress,and endoplasmic reticulum(ER)stress,were investigated.RNA sequencing analysis on mouse aortic and intestinal tissues was performed.Gut microbiota profiles of recipient mice were evaluated by metagenomic sequencing.Results:Chronic exercise improved vascular and metabolic abnormalities in donor mice.Likewise,FMT from exercised donors retarded body weight gain and slightly improved grip strength and rotarod performance in recipient mice.Exercise-associated FMT enhanced endothelial function in different arteries,suppressed vascular and intestinal stresses,and improved glucose homeostasis in recipient mice,with noted microRNA181b upregulation in aortas and intestines.Altered gut microbiota profiles and gut-derived factors(e.g.,short-chain fatty acids and glucagon-like peptide-1)as well as improved intestinal integrity shall contribute to the cardiometabolic benefits,implying a gut‒vascular connection.Conclusion:This proof-of-concept study indicates that exercised microbiota confers cardiometabolic benefits on sedentary db/db mice,extending the beneficial mechanism of exercise through gut‒vascular communication.The findings open up new therapeutic opportunities for cardiometabolic diseases and shed light on the development of exercise mimetics by targeting the gut microbiota.展开更多
Infectious bronchitis(IB),a highly contagious acute respiratory disease affecting avian species,poses significant challenges to poultry production.The causative agent,infectious bronchitis virus(IBV),exhibits a high m...Infectious bronchitis(IB),a highly contagious acute respiratory disease affecting avian species,poses significant challenges to poultry production.The causative agent,infectious bronchitis virus(IBV),exhibits a high mutation rate,leading to limited cross-protection by existing vaccines.This necessitates the development of novel vaccines.This study,based on preliminary investigations conducted by our research team,identified six potential strains(PYG QX1,ZQF QX2,FQH QX3,LYZ QX4,XXX QX5,and CSL strains)for vaccine development.Previous pathogenicity test and serum cross-neutralization experiments conducted in this study have demonstrated that the FQH QX3 strain exhibited the weakest pathogenicity and the broadest spectrum of serum neutralization,while the CSL strain showed the highest pathogenicity and was the most challenging to neutralize,posing the greatest difficulty in prevention and control.Subsequently,we constructed and rescued recombinant vaccine candidates,H120-FQH QX3,and H120-CSL,expressing the S1 and N proteins of the FQH QX3 and CSL strains,respectively.Immunization protection experiments indicated that the H120-CSL recombinant vaccine candidate exhibited the most effective immune protection,making it a promising candidate for further study and evaluation as a recombinant vaccine.The S1 and N genes of the CSL strain demonstrated strong immunogenicity,making them potential candidate antigen genes for future vaccine development.展开更多
Separators in supercapacitors(SCs)frequently suffer from high resistance and the risk of short circuits due to inadequate electrolyte wettability,depressed mechanical properties,and insufficient thermal stability.Here...Separators in supercapacitors(SCs)frequently suffer from high resistance and the risk of short circuits due to inadequate electrolyte wettability,depressed mechanical properties,and insufficient thermal stability.Here,we develop a high-performance regenerated cellulose separator with nano-cracked structures for SCs via a binary solvent of superbase-derived ionic liquid and dimethylsulfoxide(DMSO).The unique nano-cracks with an average width of 7.45 nm arise from the acceleration of cellulose molecular reassembly by DMSO-regulated hydrogen bonding,which endows the separator with high porosity(70.2%)and excellent electrolyte retention(329%).The outstanding thermal stability(273℃)and mechanical strength(70 MPa)enable the separator to maintain its structural integrity under high temperatures and external forces.With these benefits,the SC utilizing the cellulose separator enables a high specific capacitance of 93.6 F g^(−1) at 1.0 A g^(−1) and a remarkable capacitance retention of 99.5%after 10,000 cycles compared with the commercial NKK-MPF30AC and NKK-TF4030.The robust and high-wettability cellulose separator holds promise as a superior alternative to commercial separators for advanced SCs with enhanced performance and improved safety.展开更多
A 30-year-old female patient with Bartholin’s abscess was treated by acupuncture.Before visit,she had taken wuwei xiaodu yin for 4 consecutive days,but the symptoms were not alleviated markedly and pain was worsening...A 30-year-old female patient with Bartholin’s abscess was treated by acupuncture.Before visit,she had taken wuwei xiaodu yin for 4 consecutive days,but the symptoms were not alleviated markedly and pain was worsening.According to the conditions of tongue and pulse,and physical signs,the case was differ-entiated as pathogenic heat invading blood phase;and the injury of qi and yin by the herbal decoction the patient took before.In treatment with acupuncture,the treatment principle focused on benefiting qi,nourishing yin,expelling pus from the interior and draining toxin,and promoting the circulations of meridians to stop pain.He-sea points were selected to clear heat and resolve damp,and replenish the liver and kidney;and the acupoints of bladder meridian were combined under the guidance of“taiyang dominating the openings,”aiming at elevating qi and expelling toxin from the interior.Acupuncture was given once daily.After treated for 4 days,abscess was ruptured,pain disappeared,and no recurrence was presented and no sequelae happened during over 2 years of follow-up.This case shows that acupuncture is effective on Bartholin’s abscess.By reviewing this case,it is put forward that there may by the signs before the onset of Bartholin’s abscess,and the treatment should focus on opening a way for eliminating pathogens.Moreover,the clinical trial is required to verify acupuncture effect on this disease.展开更多
基金supported by the National Natural Science Foundation of China(82371300)Zhejiang Provincial Natural Science Foundation of China(LY23H090014)Zhejiang Province Traditional Chinese Medicine Science and Technology Project(2024ZL1215).
文摘Stroke,a major cerebrovascular disease,has high morbidity and mortality.Effective methods to reduce the risk and improve the prognosis are lacking.Currently,uric acid(UA)is associated with the pathological mechanism,prognosis,and therapy of stroke.UA plays pro/anti-oxidative and pro-inflammatory roles in vivo.The specific role of UA in stroke,which may have both neuroprotective and damaging effects,remains unclear.There is a U-shaped association between serum uric acid(SUA)levels and ischemic stroke(IS).UA therapy provides neuroprotection during reperfusion therapy for acute ischemic stroke(AIS).Urate-lowering therapy(ULT)plays a protective role in IS with hyperuricemia or gout.SUA levels are associated with the cerebrovascular injury mechanism,risk,and outcomes of hemorrhagic stroke.In this review,we summarize the current research on the role of UA in stroke,providing potential targets for its prediction and treatment.
基金the financial support from the National Natural Science Foundation of China(No.92163124)Foundation for the Sichuan University and Zigong City Joint research project(No.2021CDZG-2)+1 种基金Foundation for the Sichuan University and Yibin City Strategic Cooperation Project(No.2020CDYB-32)Guangxi Key Laboratory of Low Carbon Energy Material(No.2020GKLLCEM02)。
文摘Carbon materials are considered as prospective anode candidates for potassium ion batteries(PIBs).However,the low-rate capability is hampered by slow K+diffusion kinetics and obstructed electron transport of carbon-based anodes.In this work,calcium D-gluconate derived mesoporous carbon nanosheets(CGC)were interpenetrated into the architecture of reduced graphene oxides(RGO)to form the composites of two-dimensional(2D)/2D graphene/mesoporous carbon nanosheets(RGO@CGC).CGC as a rigid skeleton can prevent the graphene layers from restacking and maintain the structural stability of the 2D/2D carbon composites of RGO@CGC.The mesopores in CGC can shorten the path of ion diffusion and facilitate the penetration of electrolytes.RGO possesses the high surface-to-volume ratio and superior electron transport capability in the honeycomb-like 2D network consisting of sp^(2)-hybridized carbon atoms.Especially,theπ-πstacking interaction between CGC and RGO enhances stable composite structure formation,expedites interlayer-electron transfer,and establishes three-dimensional(3D)ion transportation pathways.Owing to these unique structure,RGO@CGC exhibits fast and stable potassium storage capability.Furthermore,the effects of binders and electrolytes on the electrochemical performance of RGO@CGC were investigated.Finally,Prussian blue was synthesized as a positive electrode to explore the possibility of RGO@CGC as a full battery application.
基金supported by the National Natural Science Foundation of China(No.52276022).
文摘Direct air capture(DAC)is a negative carbon emission technology that faces challenges in scalability and practical deployment due to its exorbitant costs.Hou et al.(2017)integrated DAC technology with fertilization.A multi-bed desorption system driven by water provides a competitive and sustainable carbon source for indoor agriculture.
基金supported, in part, by the National Natural Science Foundation of China Grants (82430078, 82261160395, 82230081, 82004395, 82302767)the Shenzhen Medical Research Funds (B2402033, C2401029)+5 种基金the Shenzhen Fundamental Research Program (JCYJ20220818100617036)the National Key Research and Development Program of China Grants (2019YFA0906004)the Guangdong Provincial Science and Technology Innovation Council Grant (2017B030301018)the Shenzhen Key Laboratory of Cell Microenvironment Grant (ZDSYS20140509142721429)the Hubei Provincial Natural Science Foundation of China (2024AFB610)the Science Foundation of Wuhan Union Hospital (2022xhyn032)
文摘Bone has long been acknowledged as a fundamental structural entity that provides support and protection to the body’s organs.However,emerging research indicates that bone plays a crucial role in the regulation of systemic metabolism.This is achieved through the secretion of a variety of hormones,cytokines,metal ions,extracellular vesicles,and other proteins/peptides,collectively referred to as bone-derived factors(BDFs).BDFs act as a medium through which bones can exert targeted regulatory functions upon various organs,thereby underscoring the profound and concrete implications of bone in human physiology.Nevertheless,there remains a pressing need for further investigations to elucidate the underlying mechanisms that inform the effects of bone on other body systems.This review aims to summarize the current findings related to the roles of these significant modulators across different organs and metabolic contexts by regulating critical genes and signaling pathways in vivo.It also addresses their involvement in the pathogenesis of various diseases affecting the musculoskeletal system,circulatory system,glucose and lipid metabolism,central nervous system,urinary system,and reproductive system.The insights gained from this review may contribute to the development of innovative therapeutic strategies through a focused approach to bone secretomes.Continued research into BDFs is expected to enhance our understanding of bone as a multifunctional organ with diverse regulatory roles in human health.
基金supported by the Sino-German Research Project(GZ 1362)Grains Research and Development Corporation International Visiting Fellowship(UWA2406-010BGX)+1 种基金the National Natural Science Foundation of China(32171982)the Fundamental Research Funds for the Central Universities of the Chinese Government(2662023PY004).
文摘Allopolyploids often exhibit advantages in vigor and adaptability compared to diploids.A long-term goal in the economically important Brassica genus has been to develop a new allohexaploid crop type(AABBCC)by combining different diploid and allotetraploid crop species.However,early-generation allohexaploids often face challenges like unstable meiosis and low fertility,and the phenotypic performance of these synthetic lines has rarely been assessed.This study analyzes agronomic traits,fertility,and genome stability in ArArBcBcCcCc lines derived from four crosses between B.carinata and B.rapa after 9–11 selfing generations.Our results demonstrate polyploid advantage in vigor and seed traits,considerable phenotypic variation,and high fertility and genome stability.Meanwhile,parental genotypes significantly influence outcomes in advanced allohexaploids.Structural variants,largely resulting from A–C homoeologous exchanges,contribute to genomic variation and influence hexaploid genome stability,with the A sub-genome showing the highest variability.Both positive and negative impacts of SVs on fertility and seed weight are observed.Pseudo-euploids,frequently appearing,do not significantly affect fertility or other agronomic traits compared to euploids,indicating a potential pathway toward a stable allohexaploid species.These findings provide insights into the challenge and potential for developing an adaptable and stable Brassica hexaploid through selection.
基金The National Natural Science Foundation of China under contract Nos 42105052 and 42376016the Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)under contract No.SML2024SP012.
文摘The Australian monsoon system plays a pivotal role in the tropical climate system by modulating the El Niño-Southern Oscillation(ENSO)development through multi-scale ocean-atmosphere interactions.This study identifies a significant decadal weakening of the Australian cross-equatorial flow intensity over the past two decades,attributed to the concurrent westward shift of the Australian High(AH)during austral winter.These decadal changes in the Australian monsoon reduce tropical Pacific atmospheric convection and the associated westerly wind anomalies over the centralto-western Pacific,which are crucial precursors for ENSO development.This process diminishes air-sea coupling feedback,including the thermocline feedback and the Ekman feedback,ultimately decreasing the strength of warm ENSO(El Niño)events.Using the Community Earth System Model,we confirm the close linkage between the Australian monsoon and ENSO on the decadal timescale.These findings provide new insights into the coupled relationship between ENSO and monsoon variability,offering a valuable framework for understanding ENSO’s longterm modulation and improving future climate predictions.
基金funded by the Health and Medical Research Fund(Grant No.08190776)Hong Kong Research Grants Council(T12-101/23-N,SRFS2021-4S04 to Yu Huang,and T11-104/22-R to Sheng Chen)supported by a fellowship award from the Research Grants Council of the Hong Kong Special Administrative Region,China(Project No.CityU PDFS22231S01).
文摘Background:Exercise elicits cardiometabolic benefits,reducing the risks of cardiovascular diseases and type 2 diabetes.This study aimed to investigate the vascular and metabolic effects of gut microbiota from exercise-trained donors on sedentary mice with type 2 diabetes and the potential mechanism.Methods:Leptin receptor-deficient diabetic(db/db)and nondiabetic(db/m+)mice underwent running treadmill exercise for 8 weeks,during which fecal microbiota transplantation(FMT)was parallelly performed from exercise-trained to sedentary diabetic(db/db)mice.Endothelial function,glucose homeostasis,physical performance,and vascular signaling of recipient mice were assessed.Vascular and intestinal stresses,including inflammation,oxidative stress,and endoplasmic reticulum(ER)stress,were investigated.RNA sequencing analysis on mouse aortic and intestinal tissues was performed.Gut microbiota profiles of recipient mice were evaluated by metagenomic sequencing.Results:Chronic exercise improved vascular and metabolic abnormalities in donor mice.Likewise,FMT from exercised donors retarded body weight gain and slightly improved grip strength and rotarod performance in recipient mice.Exercise-associated FMT enhanced endothelial function in different arteries,suppressed vascular and intestinal stresses,and improved glucose homeostasis in recipient mice,with noted microRNA181b upregulation in aortas and intestines.Altered gut microbiota profiles and gut-derived factors(e.g.,short-chain fatty acids and glucagon-like peptide-1)as well as improved intestinal integrity shall contribute to the cardiometabolic benefits,implying a gut‒vascular connection.Conclusion:This proof-of-concept study indicates that exercised microbiota confers cardiometabolic benefits on sedentary db/db mice,extending the beneficial mechanism of exercise through gut‒vascular communication.The findings open up new therapeutic opportunities for cardiometabolic diseases and shed light on the development of exercise mimetics by targeting the gut microbiota.
基金supported by National Key R&D Program of China(2022YFD1801000)the Heyuan Branch,Guangdong Laboratory for Lingnan Modern Agriculture Project(DT20220003)+1 种基金the construction project of modern agricultural science and technology innovation alliance in Guangdong province(2023KJ128)Provincial Science and Technology Special Fund Project for Zhongshan City(major special project+ Task list management mode)(2021sdr003).
文摘Infectious bronchitis(IB),a highly contagious acute respiratory disease affecting avian species,poses significant challenges to poultry production.The causative agent,infectious bronchitis virus(IBV),exhibits a high mutation rate,leading to limited cross-protection by existing vaccines.This necessitates the development of novel vaccines.This study,based on preliminary investigations conducted by our research team,identified six potential strains(PYG QX1,ZQF QX2,FQH QX3,LYZ QX4,XXX QX5,and CSL strains)for vaccine development.Previous pathogenicity test and serum cross-neutralization experiments conducted in this study have demonstrated that the FQH QX3 strain exhibited the weakest pathogenicity and the broadest spectrum of serum neutralization,while the CSL strain showed the highest pathogenicity and was the most challenging to neutralize,posing the greatest difficulty in prevention and control.Subsequently,we constructed and rescued recombinant vaccine candidates,H120-FQH QX3,and H120-CSL,expressing the S1 and N proteins of the FQH QX3 and CSL strains,respectively.Immunization protection experiments indicated that the H120-CSL recombinant vaccine candidate exhibited the most effective immune protection,making it a promising candidate for further study and evaluation as a recombinant vaccine.The S1 and N genes of the CSL strain demonstrated strong immunogenicity,making them potential candidate antigen genes for future vaccine development.
基金supported by the National Natural Science Foundation of China(No.U22A20422,22178028)the Program of Introducing Talents of Discipline to Universities(Project 111,B21022)the 5·5 Engineering Research&Innovation Team Project of Beijing Forestry University(No.BLRC2023B01)。
文摘Separators in supercapacitors(SCs)frequently suffer from high resistance and the risk of short circuits due to inadequate electrolyte wettability,depressed mechanical properties,and insufficient thermal stability.Here,we develop a high-performance regenerated cellulose separator with nano-cracked structures for SCs via a binary solvent of superbase-derived ionic liquid and dimethylsulfoxide(DMSO).The unique nano-cracks with an average width of 7.45 nm arise from the acceleration of cellulose molecular reassembly by DMSO-regulated hydrogen bonding,which endows the separator with high porosity(70.2%)and excellent electrolyte retention(329%).The outstanding thermal stability(273℃)and mechanical strength(70 MPa)enable the separator to maintain its structural integrity under high temperatures and external forces.With these benefits,the SC utilizing the cellulose separator enables a high specific capacitance of 93.6 F g^(−1) at 1.0 A g^(−1) and a remarkable capacitance retention of 99.5%after 10,000 cycles compared with the commercial NKK-MPF30AC and NKK-TF4030.The robust and high-wettability cellulose separator holds promise as a superior alternative to commercial separators for advanced SCs with enhanced performance and improved safety.
文摘A 30-year-old female patient with Bartholin’s abscess was treated by acupuncture.Before visit,she had taken wuwei xiaodu yin for 4 consecutive days,but the symptoms were not alleviated markedly and pain was worsening.According to the conditions of tongue and pulse,and physical signs,the case was differ-entiated as pathogenic heat invading blood phase;and the injury of qi and yin by the herbal decoction the patient took before.In treatment with acupuncture,the treatment principle focused on benefiting qi,nourishing yin,expelling pus from the interior and draining toxin,and promoting the circulations of meridians to stop pain.He-sea points were selected to clear heat and resolve damp,and replenish the liver and kidney;and the acupoints of bladder meridian were combined under the guidance of“taiyang dominating the openings,”aiming at elevating qi and expelling toxin from the interior.Acupuncture was given once daily.After treated for 4 days,abscess was ruptured,pain disappeared,and no recurrence was presented and no sequelae happened during over 2 years of follow-up.This case shows that acupuncture is effective on Bartholin’s abscess.By reviewing this case,it is put forward that there may by the signs before the onset of Bartholin’s abscess,and the treatment should focus on opening a way for eliminating pathogens.Moreover,the clinical trial is required to verify acupuncture effect on this disease.
