Personalized health services are of paramount importance for the treatment and prevention of cardiorespiratory diseases,such as hypertension.The assessment of cardiorespiratory function and biometric identification(ID...Personalized health services are of paramount importance for the treatment and prevention of cardiorespiratory diseases,such as hypertension.The assessment of cardiorespiratory function and biometric identification(ID)is crucial for the effectiveness of such personalized health services.To effectively and accurately monitor pulse wave signals,thus achieving the assessment of cardiorespiratory function,a wearable photonic smart wristband based on an all-polymer sensing unit(All-PSU)is proposed.The smart wristband enables the assessment of cardiorespiratory function by continuously monitoring respiratory rate(RR),heart rate(HR),and blood pressure(BP).Furthermore,it can be utilized for biometric ID purposes.Through the analysis of pulse wave signals using power spectral density(PSD),accurate monitoring of RR and HR is achieved.Additionally,utilizing peak detection algorithms for feature extraction from pulse signals and subsequently employing a variety of machine learning methods,accurate BP monitoring and biometric ID have been realized.For biometric ID,the accuracy rate is 98.55%.Aiming to monitor RR,HR,BP,and ID,our solution demonstrates advantages in integration,functionality,and monitoring precision.These enhancements may contribute to the development of personalized health services aimed at the treatment and prevention of cardiorespiratory diseases.展开更多
The digital revolution in agriculture has introduced data-driven decision-making,where artificial intelligence,especially machine learning(ML),helps analyze large and varied data sources to improve soil quality and cr...The digital revolution in agriculture has introduced data-driven decision-making,where artificial intelligence,especially machine learning(ML),helps analyze large and varied data sources to improve soil quality and crop growth indices.Thus,a thorough evaluation of scientific publications from 2007 to 2024 was conducted via the Scopus and Web of Science databases with the PRISMA guidelines to determine the realistic role of ML in soil health and crop improvement under the SDGs.In addition,the present review focused to identify and analyze the trends,challenges,and opportunities associated with the successful implementation of ML in agriculture.The assessment of various databases clearly revealed that ML implementation depends on crop management,while its limited potential in terms of soil health was explored.ML models,such as random forest and XGBoost,have demonstrated high accuracies of up to 99%in crop yield prediction and disease detection.Advanced ML frameworks,including the SHIDS-ADLT and EfficientNetB3,have improved soil health monitoring and plant disease classification.Irrigation management using ML has achieved over 50%water savings and irrigation efficiency by 10%-35%.These findings highlight the potential of ML to improve sustainable agricultural practices and soil health.A significant improvement discussed in this review is AutoML,which simplifies ML model implementation by automating feature selection,model selection,and hyperparameter tuning,reducing dependency on ML expertise.The integration of ML with remote sensing,Internet of Things(IoT),and big data analytics is expected to further transform the precision agriculture and real-time decisionmaking approaches to optimize resource utilization.Conclusively,the present review offers a quantitative perspective on the evolution of ML in agriculture,soil health management,crop yield prediction,and resource optimization.展开更多
Real-time acquisition of human pulse signals in daily life is clinically important for cardiovascular disease monitoring and diagnosis.Here,we propose a smart photonic wristband for pulse signal monitoring based on sp...Real-time acquisition of human pulse signals in daily life is clinically important for cardiovascular disease monitoring and diagnosis.Here,we propose a smart photonic wristband for pulse signal monitoring based on speckle pattern analysis with a polymer optical fiber(POF)integrated into a sports wristband.Several different speckle pattern processing algorithms and POFs with different core diameters were evaluated.The results indicated that the smart photonic wristband had a high signal-to-noise ratio and low latency,with the measurement error controlled at approximately 3.7%.This optimized pulse signal could be used for further medical diagnosis and was capable of objectively monitoring subtle pulse signal changes,such as the pulse waveform at different positions of Cunkou and pulse waveforms before and after exercise.With the assistance of artificial intelligence(AI),functions such as gesture recognition have been realized through the established prediction model by processing pulse signals,in which the recognition accuracy reaches 95%.Our AI-assisted smart photonic wristband has potential applications for clinical treatment of cardiovascular diseases and home monitoring,paving the way for medical Internet of Things-enabled smart systems.展开更多
Blackgram, an important legume crop, faces the constraint of Mungbean yellow mosaic India virus (MYMIV)-stress resulting in severe crop penalty. MYMIV-resistant plants exhibit incompatible response via a cognate CYR1 ...Blackgram, an important legume crop, faces the constraint of Mungbean yellow mosaic India virus (MYMIV)-stress resulting in severe crop penalty. MYMIV-resistant plants exhibit incompatible response via a cognate CYR1 gene-mediated interaction with virus effector molecule. In this study, we searched for the susceptible allele of the “R” gene in Cv. T9. Southern hybridization study confirmed presence of an allele in Cv. T9. However, transcripts of the CYR1 could not be detected either by RT-PCR or by Northern hybridization in Cv. T9 and also in other susceptible blackgram line. The allele was isolated, sequenced and referred as cyr1. In silico study revealed that cyr1 also encodes a CC-NBS-LRR protein like CYR1. However the CC domain of cyr1 is truncated by 128 amino acid residues indicating functional impairment with respect to the signal transduction after pathogen invasion. Comparative 3D structural modeling, hydrogen bonding and Van der Waals interaction studies revealed differences between CYR1 and cyr1. Lys519 and Thr490 present in the largest pockets of the CYR1 are the key interacting hotspots between CYR1 and MYMIV coat protein (CP). The weak Van der Waals interactions and intermolecular hydrogen bonding between cyr1 and CP confers less stability to the molecular recognition complex, unlike CYR1. Thus, the present investigation revealed Cv. T9 shows compatible interaction with MYMIV due to the truncation in the cyr1 sequence and consequent structural difference in the N-terminal of CC-domain.展开更多
This paper points out that delayed or no supply of software can kill potential benefits associated with new mathematical ideas that have led to development of new mathematics in OR. It also points out that it is a sel...This paper points out that delayed or no supply of software can kill potential benefits associated with new mathematical ideas that have led to development of new mathematics in OR. It also points out that it is a self-created situation by the scientific community. This situation needs attention and should be resolved urgently. Many illustrative examples have been given to justify the claim</span></span><span>.展开更多
The present paper deals with the study of equilibrium positions of the motion of a system of two artificial satellites connected by a light, flexible, inextensible and non-conducting cable under the influence of solar...The present paper deals with the study of equilibrium positions of the motion of a system of two artificial satellites connected by a light, flexible, inextensible and non-conducting cable under the influence of solar radiation pressure, earth’s oblateness, shadow of the earth and air resistance. Here, we study the case of circular orbit of the centre of mass of the system. We derive differential equations of motion of the system. General solutions of the differential equations are beyond the reach. On the other hand, the general solutions do not serve our purpose. Jacobian integral of the system has also been obtained. Thereafter equilibrium positions of the motion of the system have been obtained.展开更多
Generally, wounds are of two categories, such as chronic and acute. Chronic wounds takes time to heal when compared to the acute wounds. Chronic wounds include vasculitis, non healing ulcer, pyoderma gangrenosum, and ...Generally, wounds are of two categories, such as chronic and acute. Chronic wounds takes time to heal when compared to the acute wounds. Chronic wounds include vasculitis, non healing ulcer, pyoderma gangrenosum, and diseases that cause ischemia. Chronic wounds are rapidly increasing among the elderly population with dysfunctional valves in their lower extremity deep veins, ulcer, neuropathic foot and pressure ulcers. The process of the healing of wounds has several steps with the involvement of immune cells and several other cell types. There are many evidences supporting the hypothesis that apoptosis of immune cells is involved in the wound healing process by ending inflammatory condition. It is also involved in the resolution of various phases of tissue repair. During final steps of wound healing most of the endothelial cells, macrophagesand myofibroblasts undergo apoptosis or exit from the wound, leaving a mass that contains few cells and consists mostly of collagen and other extracellular matrix proteins to provide strength to the healing tissue. This review discusses the various phases of wound healing both in the chronic and acute wounds especially during diabetes mellitus and thus support the hypothesis that the oxidative stress, apoptosis, connexins and other molecules involved in the regulation of chronic wound healing in diabetes mellitus and gives proper understanding of the mechanisms controlling apoptosis and tissue repair during diabetes and may eventually develop therapeutic modalities to fasten the healing process in diabetic patients.展开更多
This paper presents the processing of magnesium alloys and its composite through different stir casting technologies.Design and devel-opment of stir casting technology that is suitable for processing of magnesium allo...This paper presents the processing of magnesium alloys and its composite through different stir casting technologies.Design and devel-opment of stir casting technology that is suitable for processing of magnesium alloys has been done in this study.The low-cost stir casting processing of magnesium alloy and its composite with flux and without flux has been explained.The magnesium alloy and its composite have been fabricated by both the stir casting process.The micro structural characterization and mechanical properties of the developed composites has been evaluated.The optical emission spectroscopy of the developed alloy and factography of the developed alloy as well as composite was also examined.展开更多
One of today's major challenges is to provide green materials for a cleaner environment. We have conducted studies on carbon dioxide(CO2) adsorption and conversion to valuable products by an ecofriendly approach ba...One of today's major challenges is to provide green materials for a cleaner environment. We have conducted studies on carbon dioxide(CO2) adsorption and conversion to valuable products by an ecofriendly approach based in chitosan/graphene oxide(CSGO) nanocomposite film. Rheological behavior indicates that the CSGO has a better solvation property than the pure chitosan. An adsorption capacity of 1.0152 mmol CO2/g of CSGO nanocomposite at4.6 bar was observed. The catalytic behavior of the CSGO nanocomposite in the presence of tetra-n-butylammonium iodide(n-Bu4 NI) as co-catalyst was evaluated for the cycloaddition of CO2 to epoxides, to give cyclic carbonates, in the absence of any solvent. These results strongly suggest that the CSGO nanocomposite may open new vistas towards the development of ecofriendly material for catalytic conversion and adsorption of CO2 on industrial scale.展开更多
Objective:Conservative approaches in muscle-invasive bladder cancer(MIBC)have been evolved to avoid aggressive surgery,but are limited to elderly,frail,and patients medically unfit for surgery.Our study aimed to asses...Objective:Conservative approaches in muscle-invasive bladder cancer(MIBC)have been evolved to avoid aggressive surgery,but are limited to elderly,frail,and patients medically unfit for surgery.Our study aimed to assess the response rate of neoadjuvant chemotherapy(NACT)before radiotherapy(RT)in MIBC patients.Methods:Forty patients with urothelial carcinoma of stage T2-T4a,N0,M0 were enrolled between November 2013 and November 2015,and treated with three cycles of NACT with gemcitabine-cisplatin.Post-NACT response was assessed using Response Evaluation Criteria in Solid Tumors(RECIST)criteria.Patients who achieved complete response(CR)and partial response(PR)>50%were treated with radical RT,and those who had PR<50%,stable disease(SD),and progressive disease(PD)underwent radical cystectomy(RC).Survival analysis was done with Kaplan-Meier method and point-to-time events were analyzed with Cox-proportional hazards regression model.Results:After NACT,35(87.5%)patients achieved either PR>50%or CR,and were treated with RT.Five(12.5%)patients who had PR<50%,SD,or PD underwent RC.All patients who received radiation showed CR after 6 weeks.Median follow-up was 43 months(range:10-66 months)and median overall survival(OS)was not reached.Three-year OS,local control,and disease-free survival were 70.1%,60.9%,50.6%,respectively,and 50%of patients preserved their functioning bladder.Three-year OS rate was 88.9%in patients who achieved CR to NACT,73.1%in patients with PR≥50%and 40%in patients with PR<50%.Conclusion:NACT followed by RT provides a high probability of local response with bladder preservation in CR patients.Appropriate use of this treatment regimen in carefully selected patients may omit the need for morbid surgery.展开更多
Traumatic brain injury is a sudden trauma or blow on the head,and severe traumatic brain injury is a major cause of death and disability worldwide.The acute and chronic consequences following traumatic brain injury ca...Traumatic brain injury is a sudden trauma or blow on the head,and severe traumatic brain injury is a major cause of death and disability worldwide.The acute and chronic consequences following traumatic brain injury can lead to progressive secondary neurodegenerative changes and cognitive dysfunction.To date,there is no effective pharmaceutical products for the treatment to reduce secondary damage after brain injury.The discovery of extracellular vesicles has attracted considerable scientific attention due to their role in cell-to-cell communication.Extracellular vesicles have shown their potential to carry not only biological molecules but also as a drug delivery vehicle.As a carrier of molecular information,extracellular vesicles have been involved in physiological functions as well as in the modulation of immune responses.Here,we aim to provide new insights into the contrasting role of extracellular vesicles in the propagation of inflammatory responses after brain injury.As a carrier of pro-inflammatory molecules,their role as functional mediators in the pathophysiology of brain injury is discussed,addressing the inhibition of the extracellular vesicle pathway as an anti-inflammatory or neuroprotective approach to improve the outcome of both acute and chronic inflammation following brain injury.Here,we summarize therapeutic strategies to diminish the risk the neurodegeneration post brain injury and propose that neutral sphingomyelinase inhibitors could be used as potentially useful therapeutic agents for the treatment of brain injury associated neuroinflammation.展开更多
Occurrence of mafic dykes in Himalaya has been intriguing and debated since long because of its difficulty to ascent and emplacement through a thickened crust.Mafic dykes in Kumaun Lesser Himalaya(KLH)of central Indian
A possible scenario for the end of the 21st century is that the atmospheric CO2 concentration will be in the range of 510 - 760 μl·L-I and that the mean global temperature will be 1.5°C - 4.5&d...A possible scenario for the end of the 21st century is that the atmospheric CO2 concentration will be in the range of 510 - 760 μl·L-I and that the mean global temperature will be 1.5°C - 4.5°C higher than present day. One of the pre-eminent manifestations of climate change is the increase in atmospheric CO2 concentration. Both CO2 and temperature are the key variables of global climate and may cause significant changes in crop productivity. An experiment was conducted inside open top chamber (OTCs) in kharif season 2014 to evaluate the effects of CO2 enrichment and temperature rise with condition OTC1 (ambient condition), OTC2 (25% higher CO2 than ambient), OTC3 (25% higher CO2 + 2°C 】ambient temperature) and OTC4 (2°C 】ambient temperature) on physiological traits and yield of rice genotypes to identify the suitable genotypes for changing climatic conditions. The study revealed that rice genotypes performed better under elevated CO2, with slight changes in development, such as growth and in yield attributing traits, depending on the genotypes. However, the beneficial direct impact of elevated (CO2) on crop yield can be counteract by elevated temperatures. Rice genotype IR83376-B-B-24-2 was highly responsive while IR84895-B-127-CRA-5-1-1 was least responsive toward elevated CO2. Physiological traits like relative water content (RWC %), membrane stability index (MSI %), chlorophyll content, photosynthetic rate and TSS content were improved under elevated CO2. However, responses of these traits were negative with elevated temperature. We point out that studies related to changes in crop physiology and yield as a consequence of global climatic changes should be a priority due to their association with food security.展开更多
Missing, swapping, false insurance claims and reallocation of pet animals (dog) are global problems throughout the world and research done to solve this problem is minimal. Traditional biometrics and non-biometrics me...Missing, swapping, false insurance claims and reallocation of pet animals (dog) are global problems throughout the world and research done to solve this problem is minimal. Traditional biometrics and non-biometrics methods have their own boundaries and they fail to provide competent level of security to pet animal (dog). The work on animal identification based on their phenotype appearance (coat patterns) has been an active research area in recent years and automatic face recognition for dog is not reported in the literature. Dog identification needs innovative research to protect the pet animal. Therefore it is imperative to initiate research, so that future face recognition algorithm will be able to solve this important problem for identification of pet animal (like dog, cat). In this paper an attempt has been made to minimize the above mentioned problems by biometrics face recognition of dog. The contributions of this research are: 1) implementation of an existing biometrics algorithm which mitigates the effects of covariates for dogs;2) proposed fusion based method for recognition of pet animal with 94.86% accuracy. Thus in this paper, we have tried to demonstrate that face recognition of dog can be used to recognize the dog efficiently.展开更多
A noninvasive method for monitoring blood pressure, based on the principles established by Riva-Rocci and Korotkoff (K), is described;it furnishes, after a single compression-deflation cycle of the arm-encircling cuff...A noninvasive method for monitoring blood pressure, based on the principles established by Riva-Rocci and Korotkoff (K), is described;it furnishes, after a single compression-deflation cycle of the arm-encircling cuff, values of sys-tolic and diastolic blood pressures as well as the contours of the brachial arterial pulse and the corresponding volume pulse. K-sounds are detected by a single microphone situated in the cubital fossa, and the time-varying cuff pressure P(t) is read by a piezoresistive pressure sensor. The behavior of P(t) during deflation is resolved into two parts, P(t)=p(t)+b(t);p is a train of posi-tive going pulses (arising from arterial pulsa-tions), whereas b is a slowly changing baseline. Noise pulses in the microphone output are re-jected by using the observation that the first few K-sounds are emitted when p is close to a maxi-mum, and the last few when dp/dt is close to a maximum. The performance of the instrument is illustrated by showing how it copes with ambi-ent noise and involuntary manual perturbations of P, and by presenting contours of various pulses.展开更多
This paper presents a new heuristic to linearise the convex quadratic programming problem. The usual Karush-Kuhn-Tucker conditions are used but in this case a linear objective function is also formulated from the set ...This paper presents a new heuristic to linearise the convex quadratic programming problem. The usual Karush-Kuhn-Tucker conditions are used but in this case a linear objective function is also formulated from the set of linear equations and complementarity slackness conditions. An unboundedness challenge arises in the proposed formulation and this challenge is alleviated by construction of an additional constraint. The formulated linear programming problem can be solved efficiently by the available simplex or interior point algorithms. There is no restricted base entry in this new formulation. Some computational experiments were carried out and results are provided.展开更多
The interaction between the classes or within the classes shows the complexity of the design. For one smaller problem, there may be more than one software design but who will be the best;depends on the complexity leve...The interaction between the classes or within the classes shows the complexity of the design. For one smaller problem, there may be more than one software design but who will be the best;depends on the complexity level of software design. Therefore, coupling and cohesion which shows the interlinking of classes and strength of classes;control the complexity of the design. The best software object oriented design is based upon the low coupling and high cohesion level. In the present work, a real case study of Life Insurance policy for handicapped person is demonstrated through the UML Class Diagram;coupling and cohesion levels are measured and results are demonstrated in the form of tables.展开更多
The field and microstructural features coupled with mineral chemical data from microgranular enclave(ME)and host Mesoproterozoic Kanigiri granite(KG)pluton of Nellore Schist Belt(NSB),Southeastern India,have been docu...The field and microstructural features coupled with mineral chemical data from microgranular enclave(ME)and host Mesoproterozoic Kanigiri granite(KG)pluton of Nellore Schist Belt(NSB),Southeastern India,have been documented in order to infer the likely processes responsible for the origin and evolution of ME and host KG magma.The ME and host KG bear the same mineral assemblages barring the KG which does not contain amphibole;however,they are modally disequilibrated.The ME in KG is originated due to multiple intrusions of ME magmas into the crystallizing host KG magma chamber.Field and textural features indicate the dynamic magma flow,mingling,and undercooling of the ME against a relatively cooler surface of host KG magma.The presence of NSB country rock xenoliths and its diffuse boundaries suggest the intrusive relation and marginal assimilation by the intruding KG magma.The occasional cumulate texture in the ME appears to have formed by the accumulation of early-formed minerals that crystallized rapidly in the ME magma globules.The ME shows the magmatically deform features developed due to the flowage and erosion by the subsequent intrusions of ME magma pulses into the crystallizing host KG magma chamber.The ME amphiboles show unusual composition as ferro-edenitic hornblende to potassian-hastingsitic hornblende,that crystallized in the subalkaline-alkaline transition,low fO_(2)(reducing to mildly oxidizing)magma.The unusual extremely low Mg/Mg+Fe^(t)=0.015(avg.)of ME amphiboles may be related to the changing physico-chemical(P,T,fO_(2),and H_(2)O)condition of the ME magma or they might have crystallized in equilibrium with more evolved KG magma.The KG(FeOt/MgO=37.04,avg.)and ME(FeO~t/MgO=77.72,avg.)biotites are siderophyllite,and buffered between QFM and NNO syn-crystallizing in the water undersaturated(H_(2O)≈3.58 wt.%in KG;≈3.53wt.%in ME),alkaline anorogenic(A-type)host magmas that were emplaced at mid-crustal(4–5 kbar;17 km)depth.Field,microtextural and mineral chemical evidences suggest that the alkaline KG magma originated from crustal source and evolved through synchronous fractionation,mixing,and mingling with coeval ME magmas in the KG magma chamber.展开更多
Zn0.90Ni0.10O nanoparticles have been synthesized by single-bath two-electrode electrodeposition at constant voltage. X-ray diffraction, UV vis and photoluminescence studies reveal that a single-phase polycrystalline ...Zn0.90Ni0.10O nanoparticles have been synthesized by single-bath two-electrode electrodeposition at constant voltage. X-ray diffraction, UV vis and photoluminescence studies reveal that a single-phase polycrystalline hcp wurtzite crystal structure of ZnO is evolved. The material consists of a large number of defects such as oxygen vacancy (Ov) and zinc interstitial (Zi). The magnetization study reveals that the sample exhibits room-temperature global ferromagnetism and the ferromagnetic ordering seems to be defect induced via bound magnetic polaron mechanism, and double exchange is also expected to have played role. Interesting optoelectronic properties have been found in the synthesized sample and the material seems to be a potential candidate to be used as a UV sensor. Such a transition metal doped ZnO based dilute magnetic semiconducting system exhibiting room-temperature ferromagnetism is likely to be first of its kind in the sense that such materials have not yet been reported to be synthesized by the simple method of electrodeposition to the best of our knowledge on the basis of ample literature review.展开更多
基金funded by the National Key R&D Program of China(2022YFE0140400)the National Natural Science Foundation of China(62405027, 62111530238, 62003046)+3 种基金Supporting project of major scientific research projects of Beijing Normal University at Zhuhai (ZHPT2023007)supported by the Tang Scholar of Beijing Normal Universityco-funded by the financial support of the European Union under the REFRESH-Research Excellence For REgion Sustainability and High-tech Industries project number CZ.10.03.01/00/22003/0000048 via the Operational Programme Just Transitionthe scope of the projects CICECO-Aveiro Institute of Materials, UIDB/50011/2020 (DOI 10.54499/UIDB/50011/2020), UIDP/50011/2020 (DOI 10.54499/UIDP/50011/2020) & LA/P/0006/2020 (DOI 10.54499/LA/P/0006/2020) financed by national funds through the FCT/MCTES (PIDDAC)
文摘Personalized health services are of paramount importance for the treatment and prevention of cardiorespiratory diseases,such as hypertension.The assessment of cardiorespiratory function and biometric identification(ID)is crucial for the effectiveness of such personalized health services.To effectively and accurately monitor pulse wave signals,thus achieving the assessment of cardiorespiratory function,a wearable photonic smart wristband based on an all-polymer sensing unit(All-PSU)is proposed.The smart wristband enables the assessment of cardiorespiratory function by continuously monitoring respiratory rate(RR),heart rate(HR),and blood pressure(BP).Furthermore,it can be utilized for biometric ID purposes.Through the analysis of pulse wave signals using power spectral density(PSD),accurate monitoring of RR and HR is achieved.Additionally,utilizing peak detection algorithms for feature extraction from pulse signals and subsequently employing a variety of machine learning methods,accurate BP monitoring and biometric ID have been realized.For biometric ID,the accuracy rate is 98.55%.Aiming to monitor RR,HR,BP,and ID,our solution demonstrates advantages in integration,functionality,and monitoring precision.These enhancements may contribute to the development of personalized health services aimed at the treatment and prevention of cardiorespiratory diseases.
基金supported by the Ministry of Science and Higher Education of the Russian Federation(no.FENW-2023-0008)the Strategic Academic Leadership Program of Southern Federal University,known as“Priority 2030”.
文摘The digital revolution in agriculture has introduced data-driven decision-making,where artificial intelligence,especially machine learning(ML),helps analyze large and varied data sources to improve soil quality and crop growth indices.Thus,a thorough evaluation of scientific publications from 2007 to 2024 was conducted via the Scopus and Web of Science databases with the PRISMA guidelines to determine the realistic role of ML in soil health and crop improvement under the SDGs.In addition,the present review focused to identify and analyze the trends,challenges,and opportunities associated with the successful implementation of ML in agriculture.The assessment of various databases clearly revealed that ML implementation depends on crop management,while its limited potential in terms of soil health was explored.ML models,such as random forest and XGBoost,have demonstrated high accuracies of up to 99%in crop yield prediction and disease detection.Advanced ML frameworks,including the SHIDS-ADLT and EfficientNetB3,have improved soil health monitoring and plant disease classification.Irrigation management using ML has achieved over 50%water savings and irrigation efficiency by 10%-35%.These findings highlight the potential of ML to improve sustainable agricultural practices and soil health.A significant improvement discussed in this review is AutoML,which simplifies ML model implementation by automating feature selection,model selection,and hyperparameter tuning,reducing dependency on ML expertise.The integration of ML with remote sensing,Internet of Things(IoT),and big data analytics is expected to further transform the precision agriculture and real-time decisionmaking approaches to optimize resource utilization.Conclusively,the present review offers a quantitative perspective on the evolution of ML in agriculture,soil health management,crop yield prediction,and resource optimization.
基金financial supports from National Key R&D Program of China (2022YFE0140400)National Natural Science Foundation of China(62003046, 62111530238)+7 种基金Guangdong Basic and Applied Basic Research Foundation (2021A1515011997)The Supplemental Funds for Major Scientific Research Projects of Beijing Normal University,Zhuhai(ZHPT2023007)Special project in key field of Guangdong Provincial Department of Education (2021ZDZX1050)The Innovation Team Project of Guangdong Provincial Department of Education (2021KCXTD014)Fundação para a Ciência e a Tecnologia (FCT) through the 2021.00667CEECIND (iAqua project)PTDC/EEI-EEE/0415/2021 (DigiAqua project)The project i3N,UIDB/50025/2020 n&UIDP/50025/2020, financed by national funds through the FCT/MEC
文摘Real-time acquisition of human pulse signals in daily life is clinically important for cardiovascular disease monitoring and diagnosis.Here,we propose a smart photonic wristband for pulse signal monitoring based on speckle pattern analysis with a polymer optical fiber(POF)integrated into a sports wristband.Several different speckle pattern processing algorithms and POFs with different core diameters were evaluated.The results indicated that the smart photonic wristband had a high signal-to-noise ratio and low latency,with the measurement error controlled at approximately 3.7%.This optimized pulse signal could be used for further medical diagnosis and was capable of objectively monitoring subtle pulse signal changes,such as the pulse waveform at different positions of Cunkou and pulse waveforms before and after exercise.With the assistance of artificial intelligence(AI),functions such as gesture recognition have been realized through the established prediction model by processing pulse signals,in which the recognition accuracy reaches 95%.Our AI-assisted smart photonic wristband has potential applications for clinical treatment of cardiovascular diseases and home monitoring,paving the way for medical Internet of Things-enabled smart systems.
文摘Blackgram, an important legume crop, faces the constraint of Mungbean yellow mosaic India virus (MYMIV)-stress resulting in severe crop penalty. MYMIV-resistant plants exhibit incompatible response via a cognate CYR1 gene-mediated interaction with virus effector molecule. In this study, we searched for the susceptible allele of the “R” gene in Cv. T9. Southern hybridization study confirmed presence of an allele in Cv. T9. However, transcripts of the CYR1 could not be detected either by RT-PCR or by Northern hybridization in Cv. T9 and also in other susceptible blackgram line. The allele was isolated, sequenced and referred as cyr1. In silico study revealed that cyr1 also encodes a CC-NBS-LRR protein like CYR1. However the CC domain of cyr1 is truncated by 128 amino acid residues indicating functional impairment with respect to the signal transduction after pathogen invasion. Comparative 3D structural modeling, hydrogen bonding and Van der Waals interaction studies revealed differences between CYR1 and cyr1. Lys519 and Thr490 present in the largest pockets of the CYR1 are the key interacting hotspots between CYR1 and MYMIV coat protein (CP). The weak Van der Waals interactions and intermolecular hydrogen bonding between cyr1 and CP confers less stability to the molecular recognition complex, unlike CYR1. Thus, the present investigation revealed Cv. T9 shows compatible interaction with MYMIV due to the truncation in the cyr1 sequence and consequent structural difference in the N-terminal of CC-domain.
文摘This paper points out that delayed or no supply of software can kill potential benefits associated with new mathematical ideas that have led to development of new mathematics in OR. It also points out that it is a self-created situation by the scientific community. This situation needs attention and should be resolved urgently. Many illustrative examples have been given to justify the claim</span></span><span>.
文摘The present paper deals with the study of equilibrium positions of the motion of a system of two artificial satellites connected by a light, flexible, inextensible and non-conducting cable under the influence of solar radiation pressure, earth’s oblateness, shadow of the earth and air resistance. Here, we study the case of circular orbit of the centre of mass of the system. We derive differential equations of motion of the system. General solutions of the differential equations are beyond the reach. On the other hand, the general solutions do not serve our purpose. Jacobian integral of the system has also been obtained. Thereafter equilibrium positions of the motion of the system have been obtained.
文摘Generally, wounds are of two categories, such as chronic and acute. Chronic wounds takes time to heal when compared to the acute wounds. Chronic wounds include vasculitis, non healing ulcer, pyoderma gangrenosum, and diseases that cause ischemia. Chronic wounds are rapidly increasing among the elderly population with dysfunctional valves in their lower extremity deep veins, ulcer, neuropathic foot and pressure ulcers. The process of the healing of wounds has several steps with the involvement of immune cells and several other cell types. There are many evidences supporting the hypothesis that apoptosis of immune cells is involved in the wound healing process by ending inflammatory condition. It is also involved in the resolution of various phases of tissue repair. During final steps of wound healing most of the endothelial cells, macrophagesand myofibroblasts undergo apoptosis or exit from the wound, leaving a mass that contains few cells and consists mostly of collagen and other extracellular matrix proteins to provide strength to the healing tissue. This review discusses the various phases of wound healing both in the chronic and acute wounds especially during diabetes mellitus and thus support the hypothesis that the oxidative stress, apoptosis, connexins and other molecules involved in the regulation of chronic wound healing in diabetes mellitus and gives proper understanding of the mechanisms controlling apoptosis and tissue repair during diabetes and may eventually develop therapeutic modalities to fasten the healing process in diabetic patients.
基金sponsored by WB TEQIP-II funds received at KNIT Sultanpur UP,India.
文摘This paper presents the processing of magnesium alloys and its composite through different stir casting technologies.Design and devel-opment of stir casting technology that is suitable for processing of magnesium alloys has been done in this study.The low-cost stir casting processing of magnesium alloy and its composite with flux and without flux has been explained.The magnesium alloy and its composite have been fabricated by both the stir casting process.The micro structural characterization and mechanical properties of the developed composites has been evaluated.The optical emission spectroscopy of the developed alloy and factography of the developed alloy as well as composite was also examined.
基金supported by the KU Brain Pool 2017 of Konkuk University,Seoul,South KoreaFundacao para a Ciência e a Tecnologia(FCT),Portugal(SFRH/BPD/86507/2012)Centro de Quimica de Coimbra(CQC),University of Coimbra for their support
文摘One of today's major challenges is to provide green materials for a cleaner environment. We have conducted studies on carbon dioxide(CO2) adsorption and conversion to valuable products by an ecofriendly approach based in chitosan/graphene oxide(CSGO) nanocomposite film. Rheological behavior indicates that the CSGO has a better solvation property than the pure chitosan. An adsorption capacity of 1.0152 mmol CO2/g of CSGO nanocomposite at4.6 bar was observed. The catalytic behavior of the CSGO nanocomposite in the presence of tetra-n-butylammonium iodide(n-Bu4 NI) as co-catalyst was evaluated for the cycloaddition of CO2 to epoxides, to give cyclic carbonates, in the absence of any solvent. These results strongly suggest that the CSGO nanocomposite may open new vistas towards the development of ecofriendly material for catalytic conversion and adsorption of CO2 on industrial scale.
文摘Objective:Conservative approaches in muscle-invasive bladder cancer(MIBC)have been evolved to avoid aggressive surgery,but are limited to elderly,frail,and patients medically unfit for surgery.Our study aimed to assess the response rate of neoadjuvant chemotherapy(NACT)before radiotherapy(RT)in MIBC patients.Methods:Forty patients with urothelial carcinoma of stage T2-T4a,N0,M0 were enrolled between November 2013 and November 2015,and treated with three cycles of NACT with gemcitabine-cisplatin.Post-NACT response was assessed using Response Evaluation Criteria in Solid Tumors(RECIST)criteria.Patients who achieved complete response(CR)and partial response(PR)>50%were treated with radical RT,and those who had PR<50%,stable disease(SD),and progressive disease(PD)underwent radical cystectomy(RC).Survival analysis was done with Kaplan-Meier method and point-to-time events were analyzed with Cox-proportional hazards regression model.Results:After NACT,35(87.5%)patients achieved either PR>50%or CR,and were treated with RT.Five(12.5%)patients who had PR<50%,SD,or PD underwent RC.All patients who received radiation showed CR after 6 weeks.Median follow-up was 43 months(range:10-66 months)and median overall survival(OS)was not reached.Three-year OS,local control,and disease-free survival were 70.1%,60.9%,50.6%,respectively,and 50%of patients preserved their functioning bladder.Three-year OS rate was 88.9%in patients who achieved CR to NACT,73.1%in patients with PR≥50%and 40%in patients with PR<50%.Conclusion:NACT followed by RT provides a high probability of local response with bladder preservation in CR patients.Appropriate use of this treatment regimen in carefully selected patients may omit the need for morbid surgery.
基金This work was in part supported by the Plough Center for Sterile Drug Delivery Solution at the University of Tennessee Health Science Center(to SK).
文摘Traumatic brain injury is a sudden trauma or blow on the head,and severe traumatic brain injury is a major cause of death and disability worldwide.The acute and chronic consequences following traumatic brain injury can lead to progressive secondary neurodegenerative changes and cognitive dysfunction.To date,there is no effective pharmaceutical products for the treatment to reduce secondary damage after brain injury.The discovery of extracellular vesicles has attracted considerable scientific attention due to their role in cell-to-cell communication.Extracellular vesicles have shown their potential to carry not only biological molecules but also as a drug delivery vehicle.As a carrier of molecular information,extracellular vesicles have been involved in physiological functions as well as in the modulation of immune responses.Here,we aim to provide new insights into the contrasting role of extracellular vesicles in the propagation of inflammatory responses after brain injury.As a carrier of pro-inflammatory molecules,their role as functional mediators in the pathophysiology of brain injury is discussed,addressing the inhibition of the extracellular vesicle pathway as an anti-inflammatory or neuroprotective approach to improve the outcome of both acute and chronic inflammation following brain injury.Here,we summarize therapeutic strategies to diminish the risk the neurodegeneration post brain injury and propose that neutral sphingomyelinase inhibitors could be used as potentially useful therapeutic agents for the treatment of brain injury associated neuroinflammation.
基金supported under a DST (ESS/16/290/2006) grant sanctioned to Santosh Kumar
文摘Occurrence of mafic dykes in Himalaya has been intriguing and debated since long because of its difficulty to ascent and emplacement through a thickened crust.Mafic dykes in Kumaun Lesser Himalaya(KLH)of central Indian
文摘A possible scenario for the end of the 21st century is that the atmospheric CO2 concentration will be in the range of 510 - 760 μl·L-I and that the mean global temperature will be 1.5°C - 4.5°C higher than present day. One of the pre-eminent manifestations of climate change is the increase in atmospheric CO2 concentration. Both CO2 and temperature are the key variables of global climate and may cause significant changes in crop productivity. An experiment was conducted inside open top chamber (OTCs) in kharif season 2014 to evaluate the effects of CO2 enrichment and temperature rise with condition OTC1 (ambient condition), OTC2 (25% higher CO2 than ambient), OTC3 (25% higher CO2 + 2°C 】ambient temperature) and OTC4 (2°C 】ambient temperature) on physiological traits and yield of rice genotypes to identify the suitable genotypes for changing climatic conditions. The study revealed that rice genotypes performed better under elevated CO2, with slight changes in development, such as growth and in yield attributing traits, depending on the genotypes. However, the beneficial direct impact of elevated (CO2) on crop yield can be counteract by elevated temperatures. Rice genotype IR83376-B-B-24-2 was highly responsive while IR84895-B-127-CRA-5-1-1 was least responsive toward elevated CO2. Physiological traits like relative water content (RWC %), membrane stability index (MSI %), chlorophyll content, photosynthetic rate and TSS content were improved under elevated CO2. However, responses of these traits were negative with elevated temperature. We point out that studies related to changes in crop physiology and yield as a consequence of global climatic changes should be a priority due to their association with food security.
文摘Missing, swapping, false insurance claims and reallocation of pet animals (dog) are global problems throughout the world and research done to solve this problem is minimal. Traditional biometrics and non-biometrics methods have their own boundaries and they fail to provide competent level of security to pet animal (dog). The work on animal identification based on their phenotype appearance (coat patterns) has been an active research area in recent years and automatic face recognition for dog is not reported in the literature. Dog identification needs innovative research to protect the pet animal. Therefore it is imperative to initiate research, so that future face recognition algorithm will be able to solve this important problem for identification of pet animal (like dog, cat). In this paper an attempt has been made to minimize the above mentioned problems by biometrics face recognition of dog. The contributions of this research are: 1) implementation of an existing biometrics algorithm which mitigates the effects of covariates for dogs;2) proposed fusion based method for recognition of pet animal with 94.86% accuracy. Thus in this paper, we have tried to demonstrate that face recognition of dog can be used to recognize the dog efficiently.
文摘A noninvasive method for monitoring blood pressure, based on the principles established by Riva-Rocci and Korotkoff (K), is described;it furnishes, after a single compression-deflation cycle of the arm-encircling cuff, values of sys-tolic and diastolic blood pressures as well as the contours of the brachial arterial pulse and the corresponding volume pulse. K-sounds are detected by a single microphone situated in the cubital fossa, and the time-varying cuff pressure P(t) is read by a piezoresistive pressure sensor. The behavior of P(t) during deflation is resolved into two parts, P(t)=p(t)+b(t);p is a train of posi-tive going pulses (arising from arterial pulsa-tions), whereas b is a slowly changing baseline. Noise pulses in the microphone output are re-jected by using the observation that the first few K-sounds are emitted when p is close to a maxi-mum, and the last few when dp/dt is close to a maximum. The performance of the instrument is illustrated by showing how it copes with ambi-ent noise and involuntary manual perturbations of P, and by presenting contours of various pulses.
文摘This paper presents a new heuristic to linearise the convex quadratic programming problem. The usual Karush-Kuhn-Tucker conditions are used but in this case a linear objective function is also formulated from the set of linear equations and complementarity slackness conditions. An unboundedness challenge arises in the proposed formulation and this challenge is alleviated by construction of an additional constraint. The formulated linear programming problem can be solved efficiently by the available simplex or interior point algorithms. There is no restricted base entry in this new formulation. Some computational experiments were carried out and results are provided.
文摘The interaction between the classes or within the classes shows the complexity of the design. For one smaller problem, there may be more than one software design but who will be the best;depends on the complexity level of software design. Therefore, coupling and cohesion which shows the interlinking of classes and strength of classes;control the complexity of the design. The best software object oriented design is based upon the low coupling and high cohesion level. In the present work, a real case study of Life Insurance policy for handicapped person is demonstrated through the UML Class Diagram;coupling and cohesion levels are measured and results are demonstrated in the form of tables.
基金UGC-Dr.D.S.Kothari Postdoctoral FellowshipNo.F.4-2/2006(BSR)/ES/20-21/0005supported under a research grant[Mo ES/P.O.(Geo)/101(v)/2017]to SK。
文摘The field and microstructural features coupled with mineral chemical data from microgranular enclave(ME)and host Mesoproterozoic Kanigiri granite(KG)pluton of Nellore Schist Belt(NSB),Southeastern India,have been documented in order to infer the likely processes responsible for the origin and evolution of ME and host KG magma.The ME and host KG bear the same mineral assemblages barring the KG which does not contain amphibole;however,they are modally disequilibrated.The ME in KG is originated due to multiple intrusions of ME magmas into the crystallizing host KG magma chamber.Field and textural features indicate the dynamic magma flow,mingling,and undercooling of the ME against a relatively cooler surface of host KG magma.The presence of NSB country rock xenoliths and its diffuse boundaries suggest the intrusive relation and marginal assimilation by the intruding KG magma.The occasional cumulate texture in the ME appears to have formed by the accumulation of early-formed minerals that crystallized rapidly in the ME magma globules.The ME shows the magmatically deform features developed due to the flowage and erosion by the subsequent intrusions of ME magma pulses into the crystallizing host KG magma chamber.The ME amphiboles show unusual composition as ferro-edenitic hornblende to potassian-hastingsitic hornblende,that crystallized in the subalkaline-alkaline transition,low fO_(2)(reducing to mildly oxidizing)magma.The unusual extremely low Mg/Mg+Fe^(t)=0.015(avg.)of ME amphiboles may be related to the changing physico-chemical(P,T,fO_(2),and H_(2)O)condition of the ME magma or they might have crystallized in equilibrium with more evolved KG magma.The KG(FeOt/MgO=37.04,avg.)and ME(FeO~t/MgO=77.72,avg.)biotites are siderophyllite,and buffered between QFM and NNO syn-crystallizing in the water undersaturated(H_(2O)≈3.58 wt.%in KG;≈3.53wt.%in ME),alkaline anorogenic(A-type)host magmas that were emplaced at mid-crustal(4–5 kbar;17 km)depth.Field,microtextural and mineral chemical evidences suggest that the alkaline KG magma originated from crustal source and evolved through synchronous fractionation,mixing,and mingling with coeval ME magmas in the KG magma chamber.
基金Project supported by the UGC-DAE,Consortium for Scientific Research,Indore through its CRS project bearing No.CSR-IC/MSRSR-12/CRS-220/2017-18/1301.
文摘Zn0.90Ni0.10O nanoparticles have been synthesized by single-bath two-electrode electrodeposition at constant voltage. X-ray diffraction, UV vis and photoluminescence studies reveal that a single-phase polycrystalline hcp wurtzite crystal structure of ZnO is evolved. The material consists of a large number of defects such as oxygen vacancy (Ov) and zinc interstitial (Zi). The magnetization study reveals that the sample exhibits room-temperature global ferromagnetism and the ferromagnetic ordering seems to be defect induced via bound magnetic polaron mechanism, and double exchange is also expected to have played role. Interesting optoelectronic properties have been found in the synthesized sample and the material seems to be a potential candidate to be used as a UV sensor. Such a transition metal doped ZnO based dilute magnetic semiconducting system exhibiting room-temperature ferromagnetism is likely to be first of its kind in the sense that such materials have not yet been reported to be synthesized by the simple method of electrodeposition to the best of our knowledge on the basis of ample literature review.