Soft-tissue management and subsequent salvage of the lower extremity following trauma has long presented difficult challenges to the plastic surgeon.Trauma to the lower extremity can produce long-term sequelae consist...Soft-tissue management and subsequent salvage of the lower extremity following trauma has long presented difficult challenges to the plastic surgeon.Trauma to the lower extremity can produce long-term sequelae consisting of psychological trauma,functional deficits,and increased costs to the healthcare system.Avoiding incorrect management is important,and is compounded by the fact that few guidelines exist on appropriate treatment and patient counseling.This study aims to describe the authors’experience at a large limb salvage center in order to further delineate management strategies.展开更多
Despite advancements in research and technology,breast cancer remains the second leading cause of cancer-related mortality affecting women worldwide.Radiation therapy is a widely recommended adjunct to surgery due to ...Despite advancements in research and technology,breast cancer remains the second leading cause of cancer-related mortality affecting women worldwide.Radiation therapy is a widely recommended adjunct to surgery due to its significant role in reducing loco-regional recurrence.Its use,however,is not without consequences.Radiation triggers a series of pathophysiologic events leading to tissue injury;reactive oxygen species incites(1)vascular damage and chronic hypoxia;(2)an inflammatory response;and(3)activation of myofibroblasts to induce fibrosis.As a result,radiotherapy interferes with wound healing and negatively impacts the quality of the skin.These pathophysiologic consequences complicate the sequence of breast reconstruction and require surgeons to consider timing and the type of reconstruction(autologous vs.implant),with respect to radiotherapy to improve patient outcomes.In this article,we briefly review radiation-induced tissue effects and their impact on breast reconstruction.More specifically,we comment on the traditional use of autologous tissue,microsurgical technical pearls for irradiated fields,reconstructive timing paradigms,and lymphedema prevention.With continued progress,derivation,and innovation,plastic and reconstructive surgery has consistently advanced and revolutionized both medicine and surgery.This review considers the future implications of breast reconstruction and how it will impact patients,healthcare,and the field.While not an exhaustive review,we aim to provide a comprehensive discussion and insights.In summary,the authors discuss the possibilities of a paradigm shift in breast reconstruction,emphasizing the need for surgeons to have an armamentarium capable of all breast reconstruction options for the best possible patient outcomes.展开更多
文摘Soft-tissue management and subsequent salvage of the lower extremity following trauma has long presented difficult challenges to the plastic surgeon.Trauma to the lower extremity can produce long-term sequelae consisting of psychological trauma,functional deficits,and increased costs to the healthcare system.Avoiding incorrect management is important,and is compounded by the fact that few guidelines exist on appropriate treatment and patient counseling.This study aims to describe the authors’experience at a large limb salvage center in order to further delineate management strategies.
文摘Despite advancements in research and technology,breast cancer remains the second leading cause of cancer-related mortality affecting women worldwide.Radiation therapy is a widely recommended adjunct to surgery due to its significant role in reducing loco-regional recurrence.Its use,however,is not without consequences.Radiation triggers a series of pathophysiologic events leading to tissue injury;reactive oxygen species incites(1)vascular damage and chronic hypoxia;(2)an inflammatory response;and(3)activation of myofibroblasts to induce fibrosis.As a result,radiotherapy interferes with wound healing and negatively impacts the quality of the skin.These pathophysiologic consequences complicate the sequence of breast reconstruction and require surgeons to consider timing and the type of reconstruction(autologous vs.implant),with respect to radiotherapy to improve patient outcomes.In this article,we briefly review radiation-induced tissue effects and their impact on breast reconstruction.More specifically,we comment on the traditional use of autologous tissue,microsurgical technical pearls for irradiated fields,reconstructive timing paradigms,and lymphedema prevention.With continued progress,derivation,and innovation,plastic and reconstructive surgery has consistently advanced and revolutionized both medicine and surgery.This review considers the future implications of breast reconstruction and how it will impact patients,healthcare,and the field.While not an exhaustive review,we aim to provide a comprehensive discussion and insights.In summary,the authors discuss the possibilities of a paradigm shift in breast reconstruction,emphasizing the need for surgeons to have an armamentarium capable of all breast reconstruction options for the best possible patient outcomes.
