Objective:To evaluate the prevalence of nymphal stages of L serrata in mesenteric lymph nodes of camels slaughtered in Mashhad slaughterhouse,Northeast of Iran.Methods:For this purpose, mesenteric lymph nodes of 400 c...Objective:To evaluate the prevalence of nymphal stages of L serrata in mesenteric lymph nodes of camels slaughtered in Mashhad slaughterhouse,Northeast of Iran.Methods:For this purpose, mesenteric lymph nodes of 400 camels of different sex and age were examined.The lymph nodes were examined macroscopically and a digestion method was also applied for investigation of samples which was negative macroscopically.Results:The mesenteric lymph nodes of 73 camels out of 400(18.25%) were infected by L serrata nymphs.Conclusions:Prevalence of L. serrata nymphs in males and females and different age was not significantly different(P>0.05), but difference was observed between the prevalence in different seasons(P< 0.05).The potential importance of these findings to human health is discussed.This is the first report of infection with L serrate of camels in camels slaughtered at northeast of Iran.展开更多
Breast cancer,an unceasingly occurring neoplasm,is one of the major determinants of mortality in women.Several ineffective attempts have been pursued using with conventional therapies against breast cancer.Resistance ...Breast cancer,an unceasingly occurring neoplasm,is one of the major determinants of mortality in women.Several ineffective attempts have been pursued using with conventional therapies against breast cancer.Resistance to existing therapies and their respective debilitating adverse effects have led research toward a new era of cancer treatment using viruses.Virotherapy constitutes a developing treatment modality with multiple mechanisms of therapeutic activity in which the viruses can be directly oncolyticand can express transgenes or induce host immune response against tumor cells.Several different DNA-and RNA-containing viruses have been considered for virotherapy of breast cancer including adenovirus,herpes virus,vaccinia,reovirus,Newcastle Disease virus,measles virus and vesicular stomatitis virus.This review aims to summarize the viro-therapeutical agents against breast malignancies.Key Scientific Concepts of Review:In this review paper,we proposed a new strategy to virus's combinatorial treatments using several kinds of transgenes and drugs.These recombinant viruses have provided evidence of treatment efficacy against human breast cancer.展开更多
基金Supported by the research council of Shahid-Bahonar University ofKerman(grant number:1389.4.16)
文摘Objective:To evaluate the prevalence of nymphal stages of L serrata in mesenteric lymph nodes of camels slaughtered in Mashhad slaughterhouse,Northeast of Iran.Methods:For this purpose, mesenteric lymph nodes of 400 camels of different sex and age were examined.The lymph nodes were examined macroscopically and a digestion method was also applied for investigation of samples which was negative macroscopically.Results:The mesenteric lymph nodes of 73 camels out of 400(18.25%) were infected by L serrata nymphs.Conclusions:Prevalence of L. serrata nymphs in males and females and different age was not significantly different(P>0.05), but difference was observed between the prevalence in different seasons(P< 0.05).The potential importance of these findings to human health is discussed.This is the first report of infection with L serrate of camels in camels slaughtered at northeast of Iran.
文摘Breast cancer,an unceasingly occurring neoplasm,is one of the major determinants of mortality in women.Several ineffective attempts have been pursued using with conventional therapies against breast cancer.Resistance to existing therapies and their respective debilitating adverse effects have led research toward a new era of cancer treatment using viruses.Virotherapy constitutes a developing treatment modality with multiple mechanisms of therapeutic activity in which the viruses can be directly oncolyticand can express transgenes or induce host immune response against tumor cells.Several different DNA-and RNA-containing viruses have been considered for virotherapy of breast cancer including adenovirus,herpes virus,vaccinia,reovirus,Newcastle Disease virus,measles virus and vesicular stomatitis virus.This review aims to summarize the viro-therapeutical agents against breast malignancies.Key Scientific Concepts of Review:In this review paper,we proposed a new strategy to virus's combinatorial treatments using several kinds of transgenes and drugs.These recombinant viruses have provided evidence of treatment efficacy against human breast cancer.
