Objective:Angelica sinensis,a traditional Chinese herbal medicine,boasts rich history and diverse pharmacological effects,influencing the hematopoietic system,circulatory system,and immune system.This study conducted ...Objective:Angelica sinensis,a traditional Chinese herbal medicine,boasts rich history and diverse pharmacological effects,influencing the hematopoietic system,circulatory system,and immune system.This study conducted a bibliometric analysis of angelica sinensis literature over the past 15 years to identify research hotspots and gaps.Methods:Utilizing the Web of Science Core Collection(WoSCC),data was analyzed through VOSviewer and Excel,with polynomial regression assessing annual publication trends.Through co-citation analysis,keyword co-occurrence and bibliographic coupling,this study uncovered distinct knowledge structures and dynamics within agelica research,offering profound understanding of current research priorities and trends.Results:The study revealed a significant annual increase in publications on angelica sinensis.Over the past 15 years,1,588 articles by 7,960 authors from 53 countries and 1,355 organizations have been published.China demonstrated notable productivity and influence in this field.Angelica polysaccharide and Z-ligustilide emerged as the most studied active ingredients.Angelica sinensis demonstrated protective effects against apoptosis and oxidative stress-induced cell damage,with its anti-inflammatory properties becoming a focal point of recent research.The classical prescription“Danggui Buxue decoction”was extensively studied for its hematopoietic,anti-tumor effects,and ability to stabilize human iron balance and ameliorate depression.Furthermore,research on angelica sinensis has spanned multiple disciplinary areas,including pharmacology,medicinal chemistry,complementary medicine and plant sciences.Conclusions:As a pivotal gynecological drug,angelica sinensis has been the focus of extensive research endeavors over the past 15 years,yielding comprehensive fundamental studies and diverse clinical applications in hematopoiesis,immunity,and other related fields.展开更多
基金supported by the Research Project of National Natural Science Foundation of China(No.82474614)Zhejiang Chinese Medical University(No.2023JKZDZC06 and No.2023FSYYZQ07)Zhejiang Provincial Key Laboratory Project(No.2012E10002).
文摘Objective:Angelica sinensis,a traditional Chinese herbal medicine,boasts rich history and diverse pharmacological effects,influencing the hematopoietic system,circulatory system,and immune system.This study conducted a bibliometric analysis of angelica sinensis literature over the past 15 years to identify research hotspots and gaps.Methods:Utilizing the Web of Science Core Collection(WoSCC),data was analyzed through VOSviewer and Excel,with polynomial regression assessing annual publication trends.Through co-citation analysis,keyword co-occurrence and bibliographic coupling,this study uncovered distinct knowledge structures and dynamics within agelica research,offering profound understanding of current research priorities and trends.Results:The study revealed a significant annual increase in publications on angelica sinensis.Over the past 15 years,1,588 articles by 7,960 authors from 53 countries and 1,355 organizations have been published.China demonstrated notable productivity and influence in this field.Angelica polysaccharide and Z-ligustilide emerged as the most studied active ingredients.Angelica sinensis demonstrated protective effects against apoptosis and oxidative stress-induced cell damage,with its anti-inflammatory properties becoming a focal point of recent research.The classical prescription“Danggui Buxue decoction”was extensively studied for its hematopoietic,anti-tumor effects,and ability to stabilize human iron balance and ameliorate depression.Furthermore,research on angelica sinensis has spanned multiple disciplinary areas,including pharmacology,medicinal chemistry,complementary medicine and plant sciences.Conclusions:As a pivotal gynecological drug,angelica sinensis has been the focus of extensive research endeavors over the past 15 years,yielding comprehensive fundamental studies and diverse clinical applications in hematopoiesis,immunity,and other related fields.
