Purpose:To verify whether there exists any difference in higher order aberrations after undergoing myopic LASIK(laser in situ keratomileusis)with conventional ablation and customized ablation in different eyes of the ...Purpose:To verify whether there exists any difference in higher order aberrations after undergoing myopic LASIK(laser in situ keratomileusis)with conventional ablation and customized ablation in different eyes of the same patient.Methods:This was a prospective randomized study of 54 myopic eyes(27 patients)that underwent LASIK using the Nidek EC-5000 ex-cimer laser system(Nidek,Gamagori,Japan).Topography-guided customized aspheric treatment zone(CATz)was used in the first eye of the patient(study group)and the other eye of the same patient was operated on with conventional ablation(control group).Higher order aberrations[root-mean-square(RMS)in the 5-mm zone]of both groups were observed with the Nidek OPD-Scan aberrometer before and 3 months after LASIK.Preoperative mean refractive error was similar between two eyes of the same patient(t=?0.577,P>0.05).Results:Preoperatively,higher order aberrations(RMS in the 5-mm zone)in the CATz ablation and conventional groups were(0.3600±0.0341)μm and(0.2680±0.1421)μm,respectively.This difference was not statistically significant(t=1.292,P>0.05).Three months after LASIK,higher order aberrations(RMS in 5-mm zone)in the CATz ablation and conventional groups were(0.3627±0.1510)μm and(0.3991±0.1582)μm,respectively.No statistically significant difference was noted between pre-and postoperative higher order aberrations in the CATz group(t=?0.047,P>0.05).However,a statistically significant increase in higher order aberrations was observed after conventional ablation(t=?5.261,P<0.05).A statistically sig-nificant difference was noted in the increase of higher order aberrations after LASIK between groups(t=?2.050,P=0.045).Con-clusion:LASIK with conventional ablation and topography-guided CATz ablation resulted in the same BSCVA(best specta-cle-corrected visual acuity)3 month after LASIK.Higher order aberrations were increased,but the increase of higher order ab-errations after customized ablation treatment was less than that after conventional ablation.展开更多
The kinetics of formic acid oxidation (FAO) on Pd(111) in 0.1 mol/L H2SO4+0.1 mol/L HCOOH with and without addition of Na2SO4 is studied using cyclic voltammetry and potential step method, which is compared with that ...The kinetics of formic acid oxidation (FAO) on Pd(111) in 0.1 mol/L H2SO4+0.1 mol/L HCOOH with and without addition of Na2SO4 is studied using cyclic voltammetry and potential step method, which is compared with that in 0.1 mol/L HClO4. It is found that adsorbed sulfate has significant inhibition effect on FAO kinetics. After addition of 0.05 mol/L or 0.1 mol/L Na2SO4, FAO current in the negative-going scan is found to be significantly smaller than that at the same potential in the positive-going scan. We speculate that at potentials positive of the phase transition potential for the (SO4*ad)m+[(H2O)n-H3O+] or(SO4*ad)m+[Na+(H2O)n-H3O+] adlayer, the adlayer structure probably becomes denser and more stable with the increase of potential or with the addition of Na2SO4. The formation of connected adlayer network greatly enhance the stability of the adlayer, and the insertion of positive-charged H+ or Na+ into the adlayer network further reduces the electrostatic repulsion between partially charged sulfates. As a result, the destruction/desorption of compact sulfate adlayer becomes more difficult, which leaves much less free sites on the surface for FAO, and thus FAO kinetics at higher potentials and in the subsequent negative-going potential scan is significantly inhibited.展开更多
目的 探究高分辨率磁共振(MRI)成像在下丘脑-垂体病变致儿童生长发育迟缓中的应用及临床诊断。方法 选取2022年1—12月于余姚市人民医院接受治疗的下丘脑-垂体病变致生长发育迟缓患儿50例为研究对象作为观察组,另在健康查体者中随机选...目的 探究高分辨率磁共振(MRI)成像在下丘脑-垂体病变致儿童生长发育迟缓中的应用及临床诊断。方法 选取2022年1—12月于余姚市人民医院接受治疗的下丘脑-垂体病变致生长发育迟缓患儿50例为研究对象作为观察组,另在健康查体者中随机选取年龄、性别相匹配的健康儿童50例作为对照组。对比分析两组不同年龄阶段的垂体大小、垂体MRI形态学参数、垂体功能指标、MRI检查结果以及生长发育迟缓患儿MRI形态学参数与垂体功能指标的相关性。结果 与7~10岁、11~14岁对照组儿童对比,7~10岁、11~14岁观察组患儿垂体的矢状高径、矢状后径、冠状高径、冠状宽径等升高,差异有统计学意义(P<0.05)。与对照组相比,观察组患儿横径(10.26±1.16 vs. 12.64±1.39)mm、前后径(4.37±0.54 vs. 6.60±0.85)mm、体积(243.27±7.32 vs. 355.72±12.24)ml、高径(3.21±0.45 vs. 5.89±0.72)mm、黄体生成素(LH)峰(6.17±1.16 vs. 8.56±2.05)mIU/L、卵泡刺激素(FSH)峰(10.43±1.34 vs. 13.98±3.30)mIU/L、LH峰/FSH峰(0.27±0.07 vs. 0.95±0.13)、雌二醇(E_(2))(5.12±1.25 vs. 8.30±2.17)pmol/L表达有所升高,差异均有统计学意义(P<0.05)。生长发育迟缓患儿的体积、高径均与LH峰、LH峰/FSH峰、E_(2)水平呈正相关(P<0.05)。与对照组相比,观察组的垂体增生、垂体前叶发育不良、颅咽管瘤术后垂体前叶薄小、垂体柄阻断综合征等发生率较高,差异均有统计学意义(P<0.05)。结论 下丘脑-垂体病变致生长发育迟缓患儿的垂体MRI形态学参数存有异常,表现为体积上升、径线长度加长,其中垂体体积与高径与下丘脑-垂体-性腺轴的功能有紧密的关联,对临床诊断下丘脑-垂体病变致生长发育迟缓患儿有着重要的意义。展开更多
文摘Purpose:To verify whether there exists any difference in higher order aberrations after undergoing myopic LASIK(laser in situ keratomileusis)with conventional ablation and customized ablation in different eyes of the same patient.Methods:This was a prospective randomized study of 54 myopic eyes(27 patients)that underwent LASIK using the Nidek EC-5000 ex-cimer laser system(Nidek,Gamagori,Japan).Topography-guided customized aspheric treatment zone(CATz)was used in the first eye of the patient(study group)and the other eye of the same patient was operated on with conventional ablation(control group).Higher order aberrations[root-mean-square(RMS)in the 5-mm zone]of both groups were observed with the Nidek OPD-Scan aberrometer before and 3 months after LASIK.Preoperative mean refractive error was similar between two eyes of the same patient(t=?0.577,P>0.05).Results:Preoperatively,higher order aberrations(RMS in the 5-mm zone)in the CATz ablation and conventional groups were(0.3600±0.0341)μm and(0.2680±0.1421)μm,respectively.This difference was not statistically significant(t=1.292,P>0.05).Three months after LASIK,higher order aberrations(RMS in 5-mm zone)in the CATz ablation and conventional groups were(0.3627±0.1510)μm and(0.3991±0.1582)μm,respectively.No statistically significant difference was noted between pre-and postoperative higher order aberrations in the CATz group(t=?0.047,P>0.05).However,a statistically significant increase in higher order aberrations was observed after conventional ablation(t=?5.261,P<0.05).A statistically sig-nificant difference was noted in the increase of higher order aberrations after LASIK between groups(t=?2.050,P=0.045).Con-clusion:LASIK with conventional ablation and topography-guided CATz ablation resulted in the same BSCVA(best specta-cle-corrected visual acuity)3 month after LASIK.Higher order aberrations were increased,but the increase of higher order ab-errations after customized ablation treatment was less than that after conventional ablation.
基金supported by the National Natural Science Foundation of China(No.21872132 and No.21832004)973 Program from the Ministry of Science and Technology of China(No.201503932301)
文摘The kinetics of formic acid oxidation (FAO) on Pd(111) in 0.1 mol/L H2SO4+0.1 mol/L HCOOH with and without addition of Na2SO4 is studied using cyclic voltammetry and potential step method, which is compared with that in 0.1 mol/L HClO4. It is found that adsorbed sulfate has significant inhibition effect on FAO kinetics. After addition of 0.05 mol/L or 0.1 mol/L Na2SO4, FAO current in the negative-going scan is found to be significantly smaller than that at the same potential in the positive-going scan. We speculate that at potentials positive of the phase transition potential for the (SO4*ad)m+[(H2O)n-H3O+] or(SO4*ad)m+[Na+(H2O)n-H3O+] adlayer, the adlayer structure probably becomes denser and more stable with the increase of potential or with the addition of Na2SO4. The formation of connected adlayer network greatly enhance the stability of the adlayer, and the insertion of positive-charged H+ or Na+ into the adlayer network further reduces the electrostatic repulsion between partially charged sulfates. As a result, the destruction/desorption of compact sulfate adlayer becomes more difficult, which leaves much less free sites on the surface for FAO, and thus FAO kinetics at higher potentials and in the subsequent negative-going potential scan is significantly inhibited.
文摘目的 探究高分辨率磁共振(MRI)成像在下丘脑-垂体病变致儿童生长发育迟缓中的应用及临床诊断。方法 选取2022年1—12月于余姚市人民医院接受治疗的下丘脑-垂体病变致生长发育迟缓患儿50例为研究对象作为观察组,另在健康查体者中随机选取年龄、性别相匹配的健康儿童50例作为对照组。对比分析两组不同年龄阶段的垂体大小、垂体MRI形态学参数、垂体功能指标、MRI检查结果以及生长发育迟缓患儿MRI形态学参数与垂体功能指标的相关性。结果 与7~10岁、11~14岁对照组儿童对比,7~10岁、11~14岁观察组患儿垂体的矢状高径、矢状后径、冠状高径、冠状宽径等升高,差异有统计学意义(P<0.05)。与对照组相比,观察组患儿横径(10.26±1.16 vs. 12.64±1.39)mm、前后径(4.37±0.54 vs. 6.60±0.85)mm、体积(243.27±7.32 vs. 355.72±12.24)ml、高径(3.21±0.45 vs. 5.89±0.72)mm、黄体生成素(LH)峰(6.17±1.16 vs. 8.56±2.05)mIU/L、卵泡刺激素(FSH)峰(10.43±1.34 vs. 13.98±3.30)mIU/L、LH峰/FSH峰(0.27±0.07 vs. 0.95±0.13)、雌二醇(E_(2))(5.12±1.25 vs. 8.30±2.17)pmol/L表达有所升高,差异均有统计学意义(P<0.05)。生长发育迟缓患儿的体积、高径均与LH峰、LH峰/FSH峰、E_(2)水平呈正相关(P<0.05)。与对照组相比,观察组的垂体增生、垂体前叶发育不良、颅咽管瘤术后垂体前叶薄小、垂体柄阻断综合征等发生率较高,差异均有统计学意义(P<0.05)。结论 下丘脑-垂体病变致生长发育迟缓患儿的垂体MRI形态学参数存有异常,表现为体积上升、径线长度加长,其中垂体体积与高径与下丘脑-垂体-性腺轴的功能有紧密的关联,对临床诊断下丘脑-垂体病变致生长发育迟缓患儿有着重要的意义。
