Tumor cells escape host immune surveillance bydown-regulation of MHC and/or co-stimulatorymolecules.Anti-tumor immune responses are mediated primarily by T cells.A deficiency in either MHC or co-stimulatory molecules ...Tumor cells escape host immune surveillance bydown-regulation of MHC and/or co-stimulatorymolecules.Anti-tumor immune responses are mediated primarily by T cells.A deficiency in either MHC or co-stimulatory molecules on tumor cells is associated with a failure to induce anti-tumor immunity.展开更多
Based on(10087±44)×10^(6)J/ψevents collected with the BESⅢdetector,we search for the lepton number violating decay J/ψ→K^(+)K^(+)e^(-)e^(-)+c.c.for the first time.The upper limit on the branching fractio...Based on(10087±44)×10^(6)J/ψevents collected with the BESⅢdetector,we search for the lepton number violating decay J/ψ→K^(+)K^(+)e^(-)e^(-)+c.c.for the first time.The upper limit on the branching fraction of this decay is set to 2.1×10^(-9)at the 90%confidence level with a frequentist method.This is the first search for J/ψdecays with a lepton number change by two,offering valuable insights into the underlying physical processes.展开更多
Using 20.3 fb^(-1)of e^(+)e^(-)annihilation data collected at a center-of-mass energy of 3.773 GeV with the BESⅢdetector,we report on an improved search for the radiative leptonic decay D^(+)→γe^(+)ve.An upper limi...Using 20.3 fb^(-1)of e^(+)e^(-)annihilation data collected at a center-of-mass energy of 3.773 GeV with the BESⅢdetector,we report on an improved search for the radiative leptonic decay D^(+)→γe^(+)ve.An upper limit on its partial branching fraction for photon energies E_(γ)>10 MeV was determined to be 1.2×10^(-5)at a 90%confidence level;this excludes most current theoretical predictions.A sophisticated deep learning approach,which includes thorough validation and is based on the Transformer architecture,was implemented to efficiently distinguish the signal from massive backgrounds.展开更多
Based on a sample of 2.7x 10^(9)ψ(3686)events collected by the BESIII detector operating at the BEP-CII collider,the decay 4(3686)→YX_(cJ),X_(cJ)→ηηη’is analyzed.The decay modes X_(c1)and X_(c2)→ηηη’are ob...Based on a sample of 2.7x 10^(9)ψ(3686)events collected by the BESIII detector operating at the BEP-CII collider,the decay 4(3686)→YX_(cJ),X_(cJ)→ηηη’is analyzed.The decay modes X_(c1)and X_(c2)→ηηη’are observed for the first time,and their corresponding branching fractions are determined to be B(X_(c1)→ηηη’)=(1.40±0.13(stat.)±0.09(sys.))×10^(-4)and B(X_(c2)→ηηη’)=(4.18±0.84(stat.)±0.48(sys.))×10^(-5).An upper limit on the branching fraction of x_(co)→ηηη’is set as 2.59×10^(-5)at a 90%confidence level(CL).A partial wave analys-is(PWA)of the decay X_(c1)→ηηη’is performed to search for the 1^(-+)exotic stateη1(1855).The PWA result indic-ates that the structure in theηη’mass spectrum is attributed to f_(0)(1500),while in the m mass spectrum,it is attrib-uted to the 0^(++)phase space.The upper limit of B(x_(cl)→η1(1855)η)·B(η1(1855)→ηη')<9.79×10^(-5)is set based on the PWA at 90%CL.展开更多
Lepton number violation decayω→π^(+)π^(+)e^(-)e^(-)+c.c.is searched for via J/ψ→ωηusing a data sample of(1.0087±0.0044)×10^(10)J/ψevents collected via the BESIII detector at the BEPCII collider.No s...Lepton number violation decayω→π^(+)π^(+)e^(-)e^(-)+c.c.is searched for via J/ψ→ωηusing a data sample of(1.0087±0.0044)×10^(10)J/ψevents collected via the BESIII detector at the BEPCII collider.No significant signal is observed,and the upper limit on the branching fraction ofω→π^(+)π^(+)e^(-)e^(-)+c.c.at the 90%confidence level is determined for the first time to be 2.8×10^(-6).展开更多
Utilizing 4.5 fb^(-1)ofe^(+)e^(-)annihilation data collected at center-of-mass energies ranging from 4599.53 MeV to 4698.82 MeV by the BESIII detector at the BEPCII collider,we searched for singly Cabibbo-suppressed h...Utilizing 4.5 fb^(-1)ofe^(+)e^(-)annihilation data collected at center-of-mass energies ranging from 4599.53 MeV to 4698.82 MeV by the BESIII detector at the BEPCII collider,we searched for singly Cabibbo-suppressed hadronic decaysΛ_(c)^(+)→Σ^(0)K^(+)π^(0)andΛ_(c)^(+)→Σ^(0)K^(+)π^(+)π^(−)and with a single-tag method.No significant signals were observed for both decays.The upper limits on the branching fractions at the 90%confidence level were determined to be 5.0×10^(-4)for and forΛ_(c)^(+)→Σ^(0)K^(+)π^(0)and 6.5×10^(-4)forΛ_(c)^(+)→Σ^(0)K^(+)π^(+)π^(−).展开更多
文摘Tumor cells escape host immune surveillance bydown-regulation of MHC and/or co-stimulatorymolecules.Anti-tumor immune responses are mediated primarily by T cells.A deficiency in either MHC or co-stimulatory molecules on tumor cells is associated with a failure to induce anti-tumor immunity.
基金supported in part by National Key R&D Program of China under Contracts Nos.2023YFA1606000,2023YFA1606704National Natural Science Foundation of China(NSFC)under Contracts Nos.12035009,11635010,11935015,11935016,11935018,12025502,12035013,12061131003,12192260,12192261,12192262,12192263,12192264,12192265,12221005,12225509,12235017,12361141819+15 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramCAS under Contract No.YSBR-101100 Talents Program of CASThe Institute of Nuclear and Particle Physics(INPAC)Shanghai Key Laboratory for Particle Physics and CosmologyGerman Research Foundation DFG under Contract No.FOR5327Istituto Nazionale di Fisica Nucleare,ItalyKnut and Alice Wallenberg Foundation under Contracts Nos.2021.0174,2021.0299Ministry of Development of Turkey under Contract No.DPT2006K-120470National Research Foundation of Korea under Contract No.NRF-2022R1A2C1092335National Science and Technology fund of MongoliaNational Science Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources&Institutional DevelopmentResearch and Innovation of Thailand under Contract No.B50G670107Polish National Science Centre under Contract No.2024/53/B/ST2/00975Swedish Research Council under Contract No.2019.04595U.S.Department of Energy under Contract No.DE-FG02-05ER41374。
文摘Based on(10087±44)×10^(6)J/ψevents collected with the BESⅢdetector,we search for the lepton number violating decay J/ψ→K^(+)K^(+)e^(-)e^(-)+c.c.for the first time.The upper limit on the branching fraction of this decay is set to 2.1×10^(-9)at the 90%confidence level with a frequentist method.This is the first search for J/ψdecays with a lepton number change by two,offering valuable insights into the underlying physical processes.
基金supported in part by National Key R&D Program of China(2020YFA0406400,2023YFA1606000,2020YFA0406300)National Natural Science Foundation of China(NSFC)(11635010,11735014,11935015,11935016,11935018,12025502,12035009,12035013,12061131003,12192260,12192261,12192262,12192263,12192264,12192265,12221005,12225509,12235017,12361141819)+18 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility Programthe CAS Center for Excellence in Particle Physics(CCEPP)Joint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1832207)CAS(YSBR-101)100 Talents Program of CASCAS Project for Young Scientists in Basic Research(YSBR-117)The Institute of Nuclear and Particle Physics(INPAC)and Shanghai Key Laboratory for Particle Physics and CosmologyAgencia Nacional de Investigación y Desarrollo de Chile(ANID),Chile(ANID PIA/APOYO AFB230003)German Research Foundation DFG(FOR5327)Istituto Nazionale di Fisica Nucleare,ItalyKnut and Alice Wallenberg Foundation(2021.0174,2021.0299)Ministry of Development of Turkey(DPT2006K-120470)National Research Foundation of Korea(NRF-2022R1A2C1092335)National Science and Technology fund of MongoliaNational Science Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation of Thailand(B50G670107)Polish National Science Centre(2019/35/O/ST2/02907)Swedish Research Council(2019.04595)The Swedish Foundation for International Cooperation in Research and Higher Education(CH2018-7756)U.S.Department of Energy(DE-FG02-05ER41374)。
文摘Using 20.3 fb^(-1)of e^(+)e^(-)annihilation data collected at a center-of-mass energy of 3.773 GeV with the BESⅢdetector,we report on an improved search for the radiative leptonic decay D^(+)→γe^(+)ve.An upper limit on its partial branching fraction for photon energies E_(γ)>10 MeV was determined to be 1.2×10^(-5)at a 90%confidence level;this excludes most current theoretical predictions.A sophisticated deep learning approach,which includes thorough validation and is based on the Transformer architecture,was implemented to efficiently distinguish the signal from massive backgrounds.
基金National Key R&D Program of China(2023YFA1606000,2023YFA1606704)National Natural Science Foundation of China(NSFC)(11635010,11935015,11935016,11935018,12025502,12035009,12035013,12061131003,12192260,12192261,12192262,12192263,12192264,12192265,12221005,12225509,12235017,12361141819)+14 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility ProgramCAS(YSBR-101)100 Talents Program of CASThe Institute of Nuclear and Particle Physics(INPAC)and Shanghai Key Laboratory for Particle Physics and CosmologyAgencia Nacional de Investigación y Desarrollo de Chile(ANID),Chile(ANID PIA/APOYO AFB230003)German Research Foundation DFG(FOR5327)Istituto Nazionale di Fisica Nucleare,ItalyKnut and Alice Wallenberg Foundation(2021.0174,2021.0299)Ministry of Development of Turkey(DPT2006K-120470)National Research Foundation of Korea(NRF-2022R1A2C1092335)National Science and Technology fund of MongoliaNational Science Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources Institutional Development,Research and Innovation of Thailand(B50G670107)Polish National Science Centre(2024/53/B/ST2/00975)Swedish Research Council(2019.04595)U.S.Department of Energy(DE-FG02-05ER41374)。
文摘Based on a sample of 2.7x 10^(9)ψ(3686)events collected by the BESIII detector operating at the BEP-CII collider,the decay 4(3686)→YX_(cJ),X_(cJ)→ηηη’is analyzed.The decay modes X_(c1)and X_(c2)→ηηη’are observed for the first time,and their corresponding branching fractions are determined to be B(X_(c1)→ηηη’)=(1.40±0.13(stat.)±0.09(sys.))×10^(-4)and B(X_(c2)→ηηη’)=(4.18±0.84(stat.)±0.48(sys.))×10^(-5).An upper limit on the branching fraction of x_(co)→ηηη’is set as 2.59×10^(-5)at a 90%confidence level(CL).A partial wave analys-is(PWA)of the decay X_(c1)→ηηη’is performed to search for the 1^(-+)exotic stateη1(1855).The PWA result indic-ates that the structure in theηη’mass spectrum is attributed to f_(0)(1500),while in the m mass spectrum,it is attrib-uted to the 0^(++)phase space.The upper limit of B(x_(cl)→η1(1855)η)·B(η1(1855)→ηη')<9.79×10^(-5)is set based on the PWA at 90%CL.
基金Supported in part by National Key R&D Program of China(2023YFA1606000,2023YFA1606704)National Natural Science Foundation of China(NSFC)(12035009,11875170,11635010,11935015,11935016,11935018,12025502,12035013,12061131003,12192260,12192261,12192262,12192263,12192264,12192265,12221005,12225509,12235017,12361141819)+16 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility Program,CAS(YSBR-101)100 Talents Program of CASThe Institute of Nuclear and Particle Physics(INPAC)Shanghai Key Laboratory for Particle Physics and CosmologyAgencia Nacional de Investigación y Desarrollo de Chile(ANID)Chile(ANID PIA/APOYO AFB230003)ERC(758462)German Research Foundation DFG(FOR5327)Istituto Nazionale di Fisica Nucleare,ItalyKnut and Alice Wallenberg Foundation(2021.0174,2021.0299)Ministry of Development of Turkey(DPT2006K-120470)National Research Foundation of Korea(NRF-2022R1A2C1092335)National Science and Technology fund of MongoliaPolish National Science Centre(2024/53/B/ST2/00975)STFC(United Kingdom)Swedish Research Council(2019.04595)U.S.Department of Energy(DE-FG02-05ER41374)。
文摘Lepton number violation decayω→π^(+)π^(+)e^(-)e^(-)+c.c.is searched for via J/ψ→ωηusing a data sample of(1.0087±0.0044)×10^(10)J/ψevents collected via the BESIII detector at the BEPCII collider.No significant signal is observed,and the upper limit on the branching fraction ofω→π^(+)π^(+)e^(-)e^(-)+c.c.at the 90%confidence level is determined for the first time to be 2.8×10^(-6).
基金supported in part by National Key R&D Program of China(2020YFA0406300,2020YFA0406400,2023YFA1606000)National Natural Science Foundation of China(NSFC)(12205141,11635010,11735014,11935015,11935016,11935018,12025502,12035009,12035013,12061131003,12192260,12192261,12192262,12192263,12192264,12192265,12221005,12225509,12235017,12361141819)+16 种基金Natural Science Foundation of Hunan Province(2024JJ2044)the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility Programthe CAS Center for Excellence in Particle Physics(CCEPP)Joint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1832207)100 Talents Program of CASThe Institute of Nuclear and Particle Physics(INPAC)and Shanghai Key Laboratory for Particle Physics and CosmologyGerman Research Foundation DFG(FOR5327)Istituto Nazionale di Fisica Nucleare,ItalyKnut and Alice Wallenberg Foundation(2021.0174,2021.0299)Ministry of Development of Turkey(DPT2006K-120470)National Research Foundation of Korea(NRF2022R1A2C1092335)National Science and Technology fund of MongoliaNational Science Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation of Thailand(B16F640076,B50G670107)Polish National Science Centre(2019/35/O/ST2/02907)Swedish Research Council(2019.04595)The Swedish Foundation for International Cooperation in Research and Higher Education(CH2018-7756)U.S.Department of Energy(DE-FG02-05ER41374)。
文摘Utilizing 4.5 fb^(-1)ofe^(+)e^(-)annihilation data collected at center-of-mass energies ranging from 4599.53 MeV to 4698.82 MeV by the BESIII detector at the BEPCII collider,we searched for singly Cabibbo-suppressed hadronic decaysΛ_(c)^(+)→Σ^(0)K^(+)π^(0)andΛ_(c)^(+)→Σ^(0)K^(+)π^(+)π^(−)and with a single-tag method.No significant signals were observed for both decays.The upper limits on the branching fractions at the 90%confidence level were determined to be 5.0×10^(-4)for and forΛ_(c)^(+)→Σ^(0)K^(+)π^(0)and 6.5×10^(-4)forΛ_(c)^(+)→Σ^(0)K^(+)π^(+)π^(−).
