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印度既往接受过抗结核治疗患者的一线和二线抗结核药耐药谱 被引量:3
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作者 C.N.Paramasivan F.Rehman +6 位作者 F.Wares N.Sundar Mohan S.Sundar s.devi P.R.Narayanan 赵津 王雪静 《国际结核病与肺部疾病杂志》 2010年第3期116-119,共4页
本文对2001-2004年间,全印度2816例复治失败结核病患者的痰培养和药物敏感试验结果,在Chennai的结核病研究中心进行了回顾性分析。其中1498例(53%)被确诊为患有耐多药结核病(MDR-TB),671例(44.8%)至少耐一种二线抗结核药,分别为:490例(3... 本文对2001-2004年间,全印度2816例复治失败结核病患者的痰培养和药物敏感试验结果,在Chennai的结核病研究中心进行了回顾性分析。其中1498例(53%)被确诊为患有耐多药结核病(MDR-TB),671例(44.8%)至少耐一种二线抗结核药,分别为:490例(32.7%)耐乙硫异烟胺,245例(16.4%)耐氧氟沙星,169例(11.3%)耐卡那霉素;69例(4.6%)为广泛耐药结核病(XDR-TB)。尽管本结果是从高度选择的、不具代表性的患者人群中获得,但耐多药结核病患者中的二线抗结核药耐药率(包括XDR率)如此之高仍值得关注。因此,以高质量的DOTS服务来预防M/XDR-TB的产生,仍是目前的首要任务。此外,也需要尽快扩展在修改后的国家结核病控制规划(RNTCP)下的高质量的规划管理,以及更加规范规划之外对二线抗结核药的使用。 展开更多
关键词 耐药 既往治疗过的结核病 印度
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Biogenic Synthesis of Silver Nanoparticles Using Fruit Extract of Ficus Carica and Study Its Antimicrobial Activity 被引量:3
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作者 K.Logaranjan s.devi K.Pandian 《Nano Biomedicine & Engineering》 2012年第4期177-182,共6页
Biogenic synthesis of metal nanoparticles is considered to be a cost effective and eco-friendly approach.Here we have demonstrated biogenic synthesis of silver nanoparticles(AgNPs)using Ficus Carica extract at room te... Biogenic synthesis of metal nanoparticles is considered to be a cost effective and eco-friendly approach.Here we have demonstrated biogenic synthesis of silver nanoparticles(AgNPs)using Ficus Carica extract at room temperature.Ficus Carica fruit extract can be used as reducing as well as capping agent without adding any external reducing agents.The rate of formation of AgNPs was monitored by using UV-Vis spectroscopy by measuring the absorbance at 420 nm for different molar ratios of plant extract to silver nitrate concentrations.The resulting AgNPs was isolated and characterized with various instrumental methods such as FTIR,XRD and FE-SEM to study the size and shape of particles and functional group of the stabilizing agents.The particles sizes are found to be 20-25 nm ranges with face centered cubic crystal structure of AgNPs.The antimicrobial activity of AgNPs synthesized by biogenic method was tested against gram negative and gram positive micro-organism.An enhanced antimicrobial activity was observed with AgNPs synthesized from fruit extract when compared with AgNPs synthesized by EDTA method. 展开更多
关键词 Biogenic synthesis Silver nanoparticles Ficus Carica fruit extract Antimicrobial activity
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