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“课-赛-研-用”一体化的高校智能计算创新创业人才培养路径探索
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作者 陈建海 沈睿 +1 位作者 刘潇璘 刘振广 《计算机教育》 2025年第8期195-199,共5页
针对智能计算创新创业人才培养的重要性,提出“课—赛—研—用”一体化的高素质智能计算创新创业人才培养路径,阐述该路径的设计方法。结合浙江大学智能计算创新创业实验室的工作实践,围绕高素质人才培养“选对人”“做对事”与“铺对... 针对智能计算创新创业人才培养的重要性,提出“课—赛—研—用”一体化的高素质智能计算创新创业人才培养路径,阐述该路径的设计方法。结合浙江大学智能计算创新创业实验室的工作实践,围绕高素质人才培养“选对人”“做对事”与“铺对路”的目标,阐述人才选拔方法、训练内容体系以及良好的创新环境对于培养高素质智能计算创新创业人才的重要性。最后通过成果总结验证该路径的有效性。 展开更多
关键词 课赛研用 智能计算 创新创业 人才培养
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一种截止激励缓冲器结构设计及性能研究 被引量:2
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作者 王超 唐宝富 +1 位作者 芮棽 姚冬磊 《现代雷达》 CSCD 北大核心 2022年第5期97-105,共9页
为保证雷达的指向精度,舰载雷达多通过螺接的方式固定在舰壁上。随着雷达轻薄化和集成度的不断提高,这种连接方式将使雷达在水下爆炸环境中受到剧烈冲击,严重影响雷达设备安全。为此,提出了一种由截止激励缓冲器组成的阵面缓冲系统,该... 为保证雷达的指向精度,舰载雷达多通过螺接的方式固定在舰壁上。随着雷达轻薄化和集成度的不断提高,这种连接方式将使雷达在水下爆炸环境中受到剧烈冲击,严重影响雷达设备安全。为此,提出了一种由截止激励缓冲器组成的阵面缓冲系统,该缓冲系统具有低冲击下保持刚性和强冲击下呈现柔性的特点,有效解决了雷达在低冲击下保精度和强冲击下保强度的矛盾。文中通过实验与仿真相结合的方式详细介绍了缓冲器弹性元件的选择和设计及阵面缓冲系统的布置优化方法。通过原理样机的试验分析证实了阵面缓冲系统的有效性。 展开更多
关键词 舰载雷达 截止激励 缓冲器 变刚度 抗冲击
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一种截止激励抗冲击缓冲系统力学性能试验研究 被引量:1
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作者 王超 唐宝富 +1 位作者 芮棽 姚晔 《电子测量技术》 北大核心 2022年第6期143-148,共6页
为保证雷达的指向精度,舰载雷达多通过螺接的方式固定在舰壁上,这种连接方式将使雷达在水下爆炸等冲击环境中受到剧烈冲击,严重影响雷达设备的安全。为此,首先提出了一种由截止激励缓冲器组成的阵面缓冲系统,该缓冲系统具有低冲击下保... 为保证雷达的指向精度,舰载雷达多通过螺接的方式固定在舰壁上,这种连接方式将使雷达在水下爆炸等冲击环境中受到剧烈冲击,严重影响雷达设备的安全。为此,首先提出了一种由截止激励缓冲器组成的阵面缓冲系统,该缓冲系统具有低冲击下保持刚性和强冲击下呈现柔性的特点,有效解决了雷达在低冲击下保精度和强冲击下保强度的矛盾。然后,再以该阵面缓冲系统为研究对象,通过弹性元件的刚度试验、缓冲器动态特性试验、阵面缓冲系统冲击试验和颠振试验等重要试验为技术手段对新研缓冲系统的力学性能进行了系统分析,为后续新研缓冲系统的试验研究提供借鉴。 展开更多
关键词 舰载雷达 截止激励 缓冲器 试验研究 力学性能
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Association between antiplatelet medication and cerebral microbleeds in stroke-free population 被引量:2
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作者 Miao-Xin YU Ya-Nan JIA +10 位作者 Dan-Dan YANG Run-Hua ZHANG Yong JIANG Gui-Tao ZHANG Hui-Yu QIAO Hua-Lu HAN rui shen Zi-Han NING Xi-Hai ZHAO Gai-Fen LIU Yong-Jun WANG 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2022年第6期409-417,共9页
BACKGROUND Cerebral microbleeds(CMBs)may increase the risk of future intracerebral hemorrhage and ischemic stroke.However,It is unclear whether antiplatelet medication is associated with CMBs.This study aimed to inves... BACKGROUND Cerebral microbleeds(CMBs)may increase the risk of future intracerebral hemorrhage and ischemic stroke.However,It is unclear whether antiplatelet medication is associated with CMBs.This study aimed to investigate the association between antiplatelet medication and CMBs in a community-based stroke-free population.METHODS In this cross-sectional study,stroke-free participants aged 18-85 years were recruited from a community in Beijing,China.Demographic,clinical,and antiplatelet medication data were collected through a questionnaire,and all participants underwent blood tests and brain magnetic resonance imaging at 3.0T.The presence,count,and location of CMBs were evaluated using susceptibility-weighted imaging.The association between antiplatelet medication and the presence of CMBs was analyzed using multivariable logistic regression.The associations between antiplatelet medication and CMBs by location(lobar,deep brain or infratentorial,and mixed regions)were also analyzed using multinomial logistic regression.A linear regression analysis was conducted to determine the association between antiplatelet medication and the log-transformed number of CMBs.RESULTS Of the 544 participants(mean age:58.65±13.66 years,217 males),119 participants(21.88%)had CMBs,and 64 participants(11.76%)used antiplatelet medication.Antiplatelet medication was found to be associated with CMBs at any location[odds ratio(OR)=2.39,95%CI:1.24-4.58]and lobar region(OR=2.83,95%CI:1.36-5.86),but not with the number of CMBs(β=0.14,95%CI:-0.21-0.48).Among antiplatelet medications,aspirin use was found to be associated with any CMB(OR=3.17,95%CI:1.49-6.72)and lobar CMBs(OR=3.61,95%CI:1.57-8.26).CONCLUSIONS Antiplatelet medication was associated with CMBs in stroke-free participants,particularly lobar CMBs.Among antiplatelet medications,aspirin use was associated with any CMB and lobar CMBs.Our findings suggest that it might be essential to optimize the management of antiplatelet medication in the stroke-free population with a higher burden of vascular risk factors to reduce the potential risk of CMBs. 展开更多
关键词 MEDICATION 3.0T ANTIPLATELET
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Effect of Jianpi-yangwei decoction on gut fungi in the patients with gastric cancer undergoing chemotherapy 被引量:1
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作者 Chun-Jie Xiang Shuo Xu +6 位作者 Juan Wu Yu-Heng Peng rui shen Wei Dong rui-Ping Wang Zhen Zhan Jun-Feng Zhang 《Traditional Medicine Research》 2021年第2期29-43,共15页
Background:Our previous study shows that the empirical formula of Chinese medicine Jianpi-yangwei decoction(JYD)can improve the quality of life in patients with gastric cancer undergoing chemotherapy by increasing ben... Background:Our previous study shows that the empirical formula of Chinese medicine Jianpi-yangwei decoction(JYD)can improve the quality of life in patients with gastric cancer undergoing chemotherapy by increasing beneficial gut bacteria and decreasing harmful bacteria.The present study aims to investigate the effect of JYD on gut fungi in patients with gastric cancer undergoing chemotherapy.Methods:A total of 73 patients with gastric cancer undergoing chemotherapy were recruited.Twenty-nine patients in the chemotherapy group were given standard chemotherapy and 44 patients in the observation group were given JYD plus standard chemotherapy.A control group(55 cases)was recruited from the healthy medical examiners.After 3 months of treatment,life-quality score was evaluated and fecal microbiota was tested by high-throughput sequencing based on the 18S rRNA gene.Results:After treatment,life-quality score in the observation group was significantly lower than that in the chemotherapy group(P<0.05).There was no significant difference between the observation and control groups’diversity and richness indices of intestinal fungi.The Chao index for intestinal fungi in the chemotherapy group was significantly lower than that in the observation group(P<0.05).There was a significant difference between the control and chemotherapy groups in the intestinal fungi according to Shannon and Simpson indices(P<0.05).Linear discriminant analysis effect size analysis showed no significant differences among the three groups,but significant difference in intestinal fungi was observed between the observation group and the chemotherapy group.At the genus level,the relative abundance of the Aspergillus genus in the observation and control groups was significantly lower(P<0.05),the relative abundance of the Cutaneotrichosporon,Galactomyces,and Ganoderma genus taxa was significantly higher compared with those in the chemotherapy group(P<0.05),and there was no significant difference between the observation group and control group.Conclusion:JYD can ameliorate chemotherapy-induced fungal dysbacteriosis in patients with gastric cancer undergoing chemotherapy and improve the quality of life of patients. 展开更多
关键词 Gastric cancer CHEMOTHERAPY Jianpi-yangwei decoction Gut fungi Aspergillus genus Cutaneotrichosporon genus
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Contrast-enhanced ultrasonography of metanephric adenoma:a case report and literature review 被引量:1
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作者 Han-Xiang Wang Dan Wang +2 位作者 Ying-Tong Xi Lin-Yan Zhou rui shen 《Oncology and Translational Medicine》 2023年第4期189-192,共4页
Objective:To investigate the gray-scale ultrasound and contrast-enhanced ultrasound(CEUS)features of metanephric adenoma(MA)to improve our understanding and diagnostic accuracy.Methods:Contrast-enhanced ultrasound fin... Objective:To investigate the gray-scale ultrasound and contrast-enhanced ultrasound(CEUS)features of metanephric adenoma(MA)to improve our understanding and diagnostic accuracy.Methods:Contrast-enhanced ultrasound findings and clinical data of a patient with MA are reported.Results:The possibility of renal malignancy was considered after CEUS and computed tomography.A left renal nephron-sparing operation was performed using an endoscope,and MA was confirmed via surgical pathology.Conclusion:Preoperative diagnosis of MA is difficult because of atypical imaging findings.The possibility of MA should be considered when a renal mass is found,and CEUS shows a“slow-in,fast-out”enhancement pattern. 展开更多
关键词 Contrast-enhanced ultrasound Metanephric adenoma
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烧伤后增生性瘢痕患者血清中TGF-β、VEGF的浓度检测及意义
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作者 沈锐 张金明 +4 位作者 张凤刚 杜永军 宋红梅 陈晓东 徐路生 《外科(汉斯)》 2013年第4期23-26,共4页
目的:探讨烧伤后增生性瘢痕患者血清中TGF-β、VEGF浓度变化及意义。方法:选择2009,8~2011,8我科住院的烧伤后增生性瘢痕患者共74例,根据创面愈合后瘢痕增生时间长短分组,分为4组,选择12例正常人作为正常对照组,共5组。用酶联吸附法(ELI... 目的:探讨烧伤后增生性瘢痕患者血清中TGF-β、VEGF浓度变化及意义。方法:选择2009,8~2011,8我科住院的烧伤后增生性瘢痕患者共74例,根据创面愈合后瘢痕增生时间长短分组,分为4组,选择12例正常人作为正常对照组,共5组。用酶联吸附法(ELISA)检测患者血清中TGF-β、VEGF的浓度,5组之间统计比较分析。结果:瘢痕患者血清中TGF-β、VEGF含量与瘢痕增生时段关系密切,1~3月早期瘢痕组血清中TGF-β、VEGF含量开始增加,随瘢痕的发展升高,4~6个月瘢痕组血清中TGF-β、VEGF含量达到了高峰。随着瘢痕成熟,TGF-β、VEGF浓度又逐渐下降。结论:烧伤后增生性患者血清中TGF-β、VEGF的含量可较好地反映增生性瘢痕代谢活跃程度,是增生性瘢痕增生活跃程度敏感的标记物。 展开更多
关键词 增生性瘢痕 烧伤后 血清 标记物 TGF-Β VEGF
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Josephson current in an irradiated Weyl semimetal junction
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作者 Han Wang rui shen 《Chinese Physics B》 SCIE EI CAS CSCD 2021年第7期83-88,共6页
The influence of the off-resonant circularly polarized light on the Josephson current in the time-reversal broken superconducting Weyl semimetal junctions is investigated by using the Bogoliubov–de Gennes equation an... The influence of the off-resonant circularly polarized light on the Josephson current in the time-reversal broken superconducting Weyl semimetal junctions is investigated by using the Bogoliubov–de Gennes equation and the transfer matrix approach.Both the zero momentum BCS pairing states and the finite momentum Fulde–Ferrell–Larkin–Ovchinnikov(FFLO)pairing states are considered for the Weyl superconductors.When a circularly polarized light is applied,it is shown that the current phase relation remains unchanged for the BCS pairing with the increasing of incident radiation intensity A_(0).For FFLO pairing,the Josephson current exhibits the 0–πtransition and periodic oscillation as a function of A_(0).The dependence of free energy and critical current on A_(0) are also investigated. 展开更多
关键词 Weyl semimetal Josephson junction FFLO pairing
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0-π transition induced by the barrier strength in spin superconductor Josephson junctions
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作者 Wen Zeng rui shen 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第9期558-561,共4页
The Andreev-like levels and the free energy of the spin superconductor/insulator/spin superconductor junction are obtained by using the Bogoliubov-de Gennes equation. The phase dependence of the spin supercurrents exh... The Andreev-like levels and the free energy of the spin superconductor/insulator/spin superconductor junction are obtained by using the Bogoliubov-de Gennes equation. The phase dependence of the spin supercurrents exhibits a 0-π transition by changing the barrier strength. The dependences of the critical current on the barrier strength and the temperature are also presented. 展开更多
关键词 spin superconductor Josephson junction
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A Penalty Function Algorithm with Objective Parameters and Constraint Penalty Parameter for Multi-Objective Programming
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作者 Zhiqing Meng rui shen Min Jiang 《American Journal of Operations Research》 2014年第6期331-339,共9页
In this paper, we present an algorithm to solve the inequality constrained multi-objective programming (MP) by using a penalty function with objective parameters and constraint penalty parameter. First, the penalty fu... In this paper, we present an algorithm to solve the inequality constrained multi-objective programming (MP) by using a penalty function with objective parameters and constraint penalty parameter. First, the penalty function with objective parameters and constraint penalty parameter for MP and the corresponding unconstraint penalty optimization problem (UPOP) is defined. Under some conditions, a Pareto efficient solution (or a weakly-efficient solution) to UPOP is proved to be a Pareto efficient solution (or a weakly-efficient solution) to MP. The penalty function is proved to be exact under a stable condition. Then, we design an algorithm to solve MP and prove its convergence. Finally, numerical examples show that the algorithm may help decision makers to find a satisfactory solution to MP. 展开更多
关键词 MULTI-OBJECTIVE Programming PENALTY Function Objective PARAMETERS CONSTRAINT PENALTY Parameter PARETO Weakly-Efficient Solution
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An Objective Penalty Functions Algorithm for Multiobjective Optimization Problem
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作者 Zhiqing Meng rui shen Min Jiang 《American Journal of Operations Research》 2011年第4期229-235,共7页
By using the penalty function method with objective parameters, the paper presents an interactive algorithm to solve the inequality constrained multi-objective programming (MP). The MP is transformed into a single obj... By using the penalty function method with objective parameters, the paper presents an interactive algorithm to solve the inequality constrained multi-objective programming (MP). The MP is transformed into a single objective optimal problem (SOOP) with inequality constrains;and it is proved that, under some conditions, an optimal solution to SOOP is a Pareto efficient solution to MP. Then, an interactive algorithm of MP is designed accordingly. Numerical examples show that the algorithm can find a satisfactory solution to MP with objective weight value adjusted by decision maker. 展开更多
关键词 MULTIOBJECTIVE Optimization PROBLEM Objective PENALTY Function PARETO Efficient Solution INTERACTIVE ALGORITHM
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Interpenetrating double-network ANF/MXene-K^(+) aerogels enable integrated electromagnetic interference shielding,infrared camouflage,and Joule Heating in adaptive multifunctional systems
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作者 Xinlong Wang Xinpeng Hu +7 位作者 Zhigang Liu Chuanbiao Zhu rui shen Bingqing Quan Xiangyu Yan Wenling Wang Xiang Lu Jinping Qu 《Nano Research》 2025年第8期1285-1296,共12页
With the advancement of modern communication technology and military detection technology,there is an urgent need to develop lightweight,flexible,multifunctional composites that integrate efficient infrared(IR)stealth... With the advancement of modern communication technology and military detection technology,there is an urgent need to develop lightweight,flexible,multifunctional composites that integrate efficient infrared(IR)stealth,electromagnetic interference(EMI)shielding,and Joule thermal properties.Nevertheless,the preparation of multifunctional composites with the above properties remains challenging.Herein,multifunctional aerogel films were designed through potassium ionic cross-linking of MXene and aramid nanofiber(ANF),forming an enhanced interpenetrating double-network ANF/MXene-K^(+)(AMK)aerogel.The aerogel film possesses extremely low infrared emissivity(~0.097),reducing radiation temperature by more than 89.7%with 9.2 MPa tensile strength.Furthermore,the film exhibits excellent Joule heating performance,including low driving voltage(1.0 V),fast thermal response(<12.0 s),and long-term stability.Concurrently,the interpenetrating double-network structure of potassium ion-induced self-assembly of MXene nanosheets enabled AMK to demonstrate enhanced electromagnetic shielding(72.4 dB).Overall,this work provides a promising solution for fabricating multifunctional materials and demonstrates their potential in adaptive thermal camouflage systems,next-generation wearable thermal management,and EMI shielding of electronic devices. 展开更多
关键词 infrared stealth Joule heating electromagnetic interference shielding aerogel films interpenetrating double-network
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DeST 3.0:A new-generation building performance simulation platform 被引量:13
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作者 Da Yan Xin Zhou +28 位作者 Jingjing An Xuyuan Kang Fan Bu Youming Chen Yiqun Pan Yan Gao Qunli Zhang Hui Zhou Kuining Qiu Jing Liu Yan Liu Honglian Li Lei Zhang Hong Dong Lixin Sun Song Pan Xiang Zhou Zhe Tian Wenjie Zhang Ruhong Wu Hongsan Sun Yu Huang Xiaohong Su Yongwei Zhang rui shen Diankun Chen Guangyuan Wei Yixing Chen Jinqing Peng 《Building Simulation》 SCIE EI CSCD 2022年第11期1849-1868,共20页
Buildings contribute to almost 30%of total energy consumption worldwide.Developing building energy modeling programs is of great significance for lifecycle building performance assessment and optimization.Advances in ... Buildings contribute to almost 30%of total energy consumption worldwide.Developing building energy modeling programs is of great significance for lifecycle building performance assessment and optimization.Advances in novel building technologies,the requirements of high-performance computation,and the demands for multi-objective models have brought new challenges for building energy modeling software and platforms.To meet the increasing simulation demands,DeST 3.0,a new-generation building performance simulation platform,was developed and released.The structure of DeST 3.0 incorporates four simulation engines,including building analysis and simulation(BAS)engine,HVAC system engine,combined plant simulation(CPS)engine,and energy system(ES)engine,connected by air loop and water loop balancing iterations.DeST 3.0 offers numerous new simulation features,such as advanced simulation modules for building envelopes,occupant behavior and energy systems,cross-platform and compatible simulation kernel,FMI/FMU-based co-simulation functionalities,and high-performance parallel simulation architecture.DeST 3.0 has been thoroughly evaluated and validated using code verification,inter-program comparison,and case-study calibration.DeST 3.0 has been applied in various aspects throughout the building lifecycle,supporting building design,operation,retrofit analysis,code appliance,technology adaptability evaluation as well as research and education.The new generation building simulation platform DeST 3.0 provides an efficient tool and comprehensive simulation platform for lifecycle building performance analysis and optimization. 展开更多
关键词 DeST building performance SIMULATION building energy modeling
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Lysine succinylation,the metabolic bridge between cancer and immunity 被引量:1
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作者 rui shen Hongyun Ruan +4 位作者 Shuye Lin Bin Liu Hang Song Lu Li Teng Ma 《Genes & Diseases》 SCIE CSCD 2023年第6期2470-2478,共9页
Lysine succinylation is a naturally occurring post-translational modification(PTM)that regulates the stability and function of proteins.It can be regulated by enzymes such as SIRT5 and SIRT7.Recently,the effect and si... Lysine succinylation is a naturally occurring post-translational modification(PTM)that regulates the stability and function of proteins.It can be regulated by enzymes such as SIRT5 and SIRT7.Recently,the effect and significance of lysine succinylation in cancer and its implication in immunity have been extensively explored.Lysine succinylation is involved in the malignant phenotype of cancer cells.Abnormal regulation of lysine succinylation occurs in different cancers,and inhibitors targeting lysine succinylation regulatory enzymes can be used as potential anti-cancer strategies.Therefore,this review focused on the target protein lysine succinylation and its functions in cancer and immunity,in order to provide a reference for finding more potential clinical cancer targets in the future. 展开更多
关键词 IMMUNITY MITOCHONDRIA SIRT5 Succinyl-CoA SUCCINYLATION
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Levels of vaccination coverage among HIV-exposed children in China: a retrospective study 被引量:1
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作者 rui shen Ai-Ling Wang +5 位作者 Xiao-Ping Pan Ya-Ping Qiao Qian Wang Xiao-Yan Wang Shui-Ling Qu Tong Zhang 《Infectious Diseases of Poverty》 SCIE 2021年第2期98-99,共2页
Background:Vaccination is crucial for human immunodeficiency virus(HlV)-exposed children because of their increased risk of morbidity and mortality from various vaccine-preventable diseases.However,studies have shown ... Background:Vaccination is crucial for human immunodeficiency virus(HlV)-exposed children because of their increased risk of morbidity and mortality from various vaccine-preventable diseases.However,studies have shown that they are at high risk of incomplete vaccination.Although China has developed prevention of mother-to-child transmission(PMTCT)of HIV programs substantially over the past decades,few studies have investigated the immunization levels of Chinese HIV-exposed children.Therefore,we aimed to evaluate vaccination coverage and its associated factors among HIV-exposed children in China during 2016-2018. 展开更多
关键词 HIV CHILDREN COVERAGE VACCINATION China
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Networked Protection Scheme with Feeding Section as a Unit for High-speed Railway Traction Power Supply System 被引量:1
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作者 Zhengqing Han rui shen +1 位作者 Shuping Liu Shibin Gao 《CSEE Journal of Power and Energy Systems》 SCIE EI CSCD 2023年第5期1935-1941,共7页
In order to rapidly clear a fault in all-parallel autotransformer(AT)railway system,the existing protection scheme trips both faulted line and healthy line.To solve this problem,a novel unit protection scheme is propo... In order to rapidly clear a fault in all-parallel autotransformer(AT)railway system,the existing protection scheme trips both faulted line and healthy line.To solve this problem,a novel unit protection scheme is proposed in this paper.From fault characteristics measured at substation(SS),AT station(ATS)and section post(SP),we can observe that SS protective relays can detect all the faults but could not be selective,and ATS or SP relays can discriminate the faulted line but not sensitively enough;therefore,we make full use of the fault characteristics and propose a novel unit protection scheme.We employ directional distance protections at SS,ATS and SP,and unify them with networked inter-tripping signals and interlocking signals.When a forward distance protection detects a fault and does not receive inter-locking signals from reverse distance protections of other relays in a short setting time,it will trip the relevant circuit breaker and send an inter-tripping signal to other relays in the same protection unit.Field test results show the proposed scheme trips only the faulted line rapidly and never interrupts the power supply of healthy lines;therefore,the proposed protection scheme obtains both selectivity and speed. 展开更多
关键词 All-parallel AT railway system distance protection unit protection
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