目的分析牙周炎患者牙种植术后发生种植体周围炎的危险因素,并建立列线图预测模型。方法共203例患者纳入研究,并采用随机抽样法将其分为建模组(n=142)与验证组(n=61)。基于牙周炎患者发生种植体周围炎的独立危险因素,建立Logistic风险...目的分析牙周炎患者牙种植术后发生种植体周围炎的危险因素,并建立列线图预测模型。方法共203例患者纳入研究,并采用随机抽样法将其分为建模组(n=142)与验证组(n=61)。基于牙周炎患者发生种植体周围炎的独立危险因素,建立Logistic风险预测模型。采用Bootstrap法对模型进行内部验证,外部验证通过验证组完成。利用Hosmer-Lemeshow检验(H-L检验)和受试者工作特征(receiver operating characteristic,ROC)曲线下面积(area under the curve,AUC)对预测模型进行评价。结果吸烟史、糖尿病史、未定期行牙周治疗、种植体周围黏膜厚度<2 mm、前牙区种植和粘接固位修复等都是牙周炎患者种植后发生种植体周围炎的独立危险因素(P<0.05)。根据以上危险因素,建立预测牙周炎患者发生种植体周围炎的列线图模型。H-L检验的显著性水平为0.536。校准曲线显示,建模组和验证组的预测值与实测值基本一致。建模组AUC为0.906,表明此模型具有较好的判别效果。结论以吸烟史、糖尿病史、未能定期行牙周治疗、种植体周围黏膜厚度<2 mm、前牙区种植和粘接固位修复为预测因子构建的列线图模型可有效预测牙周炎患者发生种植体周围炎的概率。展开更多
This article presents a comprehensive study on the emerging near-space communications (NS-COM) within the context of space–air–ground–sea integrated network (SAGSIN). Specifically, we firstly explore the recent tec...This article presents a comprehensive study on the emerging near-space communications (NS-COM) within the context of space–air–ground–sea integrated network (SAGSIN). Specifically, we firstly explore the recent technical developments of NS-COM, followed by the discussions about motivations behind integrating NS-COM into SAGSIN. To further demonstrate the necessity of NS-COM, a comparative analysis between the NS-COM network and other counterparts in SAGSIN is conducted, covering aspects of deployment, coverage, channel characteristics, and unique problems of NS-COM network. Afterward, the technical aspects of NS-COM, including channel modeling, random access, channel estimation, array-based beam management, and joint network optimization, are examined in detail. Furthermore, we explore the potential applications of NS-COM, such as structural expansion in SAGSIN communication, civil aviation communication, remote and urgent communication, weather monitoring, and carbon neutrality. Finally, some promising research avenues are identified, including stratospheric satellite-to-ground direct links for mobile terminals, reconfigurable multiple-input multiple-output and holographic multiple-input multiple-output, federated learning in NS-COM networks, maritime communication, electromagnetic spectrum sensing and adversarial game, integrated sensing and communications, stratospheric-satellite-based radar detection and imaging, NS-COM-assisted enhanced global navigation system, NS-COM-assisted intelligent unmanned system, and free-space optical communication. Overall, this paper highlights that the NS-COM plays an indispensable role in the SAGSIN puzzle, providing substantial performance and coverage enhancement to the traditional SAGSIN architecture.展开更多
目的通过文献计量学软件对气管插管教学领域的相关文献进行统计,分析并展示2003—2023年气管插管教学文献分布和研究热点,以探索出更加切实有效的教学方法。方法计算机检索Web of Science(WOS)、中国知网和万方数据库,检索时间为2003年1...目的通过文献计量学软件对气管插管教学领域的相关文献进行统计,分析并展示2003—2023年气管插管教学文献分布和研究热点,以探索出更加切实有效的教学方法。方法计算机检索Web of Science(WOS)、中国知网和万方数据库,检索时间为2003年1月1日至2023年12月31日,检索关键词包括“endotracheal intubation”“气管插管”和“teaching”“教学”,采用VOS viewer和CiteSpace等软件对检索文献进行可视化分析。结果最终纳入英文文献442篇,中文文献819篇。英文文献大多集中发表在发达国家,其中美国发表的文献数量最多(134篇)。被引用次数超过100次的文献共计21篇,被引用最高频次为327次。发文量为6篇及以上的机构共计9个,以全印度医学科学学院与蒙彼利埃大学为中心形成重点研究集群,共有2309名作者参与了气管插管教学领域的研究。442篇文献中,关键词“endotracheal intubation”“intubation”出现次数最多。中文教学文献中共有2621名作者参与了气管插管教学领域的研究,其中第一作者发文量3篇以上的所属单位有10个。819篇文献中,关键词“气管插管”和“教学”出现次数最多。结论全球对气管插管教学的关注正在日益增加,加强气道管理和预防并发症的是气管插管教学的研究热点。展开更多
Mycoplasma pneumonia is a common community-acquired pneumonia （CAP） in Asia. Children suffering from M. pneumoniae tend to progress quickly and develop severe pneumonia with a poor prognosis.（1） Effective manageme...Mycoplasma pneumonia is a common community-acquired pneumonia （CAP） in Asia. Children suffering from M. pneumoniae tend to progress quickly and develop severe pneumonia with a poor prognosis.（1） Effective management of M. pneumoniae infections include macrolides, tetracyclines or fluoroquinolones, however, antibiotic resistance may lead to unsatisfied clinical outcome. Chinese medicine （CM） is widely used in China and some Asian countries, which have good efficacy in the treatment of M. pneumoniae, especially for severe M. Pneumonia infection.（2） It has obvious advantages in terms of fever reduction and appetite improvement. Here we report a case of a child diagnosed with severe pneumonia who received antibiotics for 20 days but with suboptimal result, however, he experienced an optimal response to CM.展开更多
Dear Editor,Japanese encephalitis(JE)is a mosquito-borne acute neurological infectious disease caused by the Japanese encephalitis virus(JEV).Globally,68,000 cases of the disease are estimated each year,with a fatalit...Dear Editor,Japanese encephalitis(JE)is a mosquito-borne acute neurological infectious disease caused by the Japanese encephalitis virus(JEV).Globally,68,000 cases of the disease are estimated each year,with a fatality rate of as high as 30%and with approximately 30%-50%of survivors suffering from severe neurological sequelae(WHO,2015).展开更多
文摘目的分析牙周炎患者牙种植术后发生种植体周围炎的危险因素,并建立列线图预测模型。方法共203例患者纳入研究,并采用随机抽样法将其分为建模组(n=142)与验证组(n=61)。基于牙周炎患者发生种植体周围炎的独立危险因素,建立Logistic风险预测模型。采用Bootstrap法对模型进行内部验证,外部验证通过验证组完成。利用Hosmer-Lemeshow检验(H-L检验)和受试者工作特征(receiver operating characteristic,ROC)曲线下面积(area under the curve,AUC)对预测模型进行评价。结果吸烟史、糖尿病史、未定期行牙周治疗、种植体周围黏膜厚度<2 mm、前牙区种植和粘接固位修复等都是牙周炎患者种植后发生种植体周围炎的独立危险因素(P<0.05)。根据以上危险因素,建立预测牙周炎患者发生种植体周围炎的列线图模型。H-L检验的显著性水平为0.536。校准曲线显示,建模组和验证组的预测值与实测值基本一致。建模组AUC为0.906,表明此模型具有较好的判别效果。结论以吸烟史、糖尿病史、未能定期行牙周治疗、种植体周围黏膜厚度<2 mm、前牙区种植和粘接固位修复为预测因子构建的列线图模型可有效预测牙周炎患者发生种植体周围炎的概率。
基金supported in part by the Beijing Nova Program,the Shandong Province Natural Science Foundation under grant ZR2022YQ62the Natural Science Foundation of China(NSFC)under grants 62071044 and U2233216.
文摘This article presents a comprehensive study on the emerging near-space communications (NS-COM) within the context of space–air–ground–sea integrated network (SAGSIN). Specifically, we firstly explore the recent technical developments of NS-COM, followed by the discussions about motivations behind integrating NS-COM into SAGSIN. To further demonstrate the necessity of NS-COM, a comparative analysis between the NS-COM network and other counterparts in SAGSIN is conducted, covering aspects of deployment, coverage, channel characteristics, and unique problems of NS-COM network. Afterward, the technical aspects of NS-COM, including channel modeling, random access, channel estimation, array-based beam management, and joint network optimization, are examined in detail. Furthermore, we explore the potential applications of NS-COM, such as structural expansion in SAGSIN communication, civil aviation communication, remote and urgent communication, weather monitoring, and carbon neutrality. Finally, some promising research avenues are identified, including stratospheric satellite-to-ground direct links for mobile terminals, reconfigurable multiple-input multiple-output and holographic multiple-input multiple-output, federated learning in NS-COM networks, maritime communication, electromagnetic spectrum sensing and adversarial game, integrated sensing and communications, stratospheric-satellite-based radar detection and imaging, NS-COM-assisted enhanced global navigation system, NS-COM-assisted intelligent unmanned system, and free-space optical communication. Overall, this paper highlights that the NS-COM plays an indispensable role in the SAGSIN puzzle, providing substantial performance and coverage enhancement to the traditional SAGSIN architecture.
文摘Mycoplasma pneumonia is a common community-acquired pneumonia （CAP） in Asia. Children suffering from M. pneumoniae tend to progress quickly and develop severe pneumonia with a poor prognosis.（1） Effective management of M. pneumoniae infections include macrolides, tetracyclines or fluoroquinolones, however, antibiotic resistance may lead to unsatisfied clinical outcome. Chinese medicine （CM） is widely used in China and some Asian countries, which have good efficacy in the treatment of M. pneumoniae, especially for severe M. Pneumonia infection.（2） It has obvious advantages in terms of fever reduction and appetite improvement. Here we report a case of a child diagnosed with severe pneumonia who received antibiotics for 20 days but with suboptimal result, however, he experienced an optimal response to CM.
文摘Dear Editor,Japanese encephalitis(JE)is a mosquito-borne acute neurological infectious disease caused by the Japanese encephalitis virus(JEV).Globally,68,000 cases of the disease are estimated each year,with a fatality rate of as high as 30%and with approximately 30%-50%of survivors suffering from severe neurological sequelae(WHO,2015).
