Hypertension is a very prevalent risk factor for cardiovascular disease. The prevalence of resistant hypertension, i.e., uncontrolled hypertension with 3 or more antihypertensive agents including 1 diuretic, is betwee...Hypertension is a very prevalent risk factor for cardiovascular disease. The prevalence of resistant hypertension, i.e., uncontrolled hypertension with 3 or more antihypertensive agents including 1 diuretic, is between 5% and 30% in the hypertensive population. The causes of resistant hypertension are multifactorial and include behavioral and biological factors, such as nonadherence to pharmacological treatment. All current treatment guidelines highlight the positive role of physical exercise as a non-pharmacological tool in the treatment of hypertension. This paper draws attention to the possible role of physical exercise as an adjunct non-pharmacological tool in the management of resistant hypertension. A few studies have investigated it, employing different methodologies, and taken together they have shown promising results. In summary, the available evidence suggests that aerobic physical exercise could be a valuable addition to the optimal pharmacological treatment of patients with resistant hypertension.展开更多
Fermented dairy products(FDP)are consumed worldwide,due to their nutritional attributes and sensory properties.In the last decade,edible insects have been the subject of research as a sustainable source of protein to ...Fermented dairy products(FDP)are consumed worldwide,due to their nutritional attributes and sensory properties.In the last decade,edible insects have been the subject of research as a sustainable source of protein to be introduced into the food industry.The mealworm(Tenebrio molitor)and buffalo worm(Alphitobius diaperinus)have demonstrated the highest consumer potential.However,this study aims to demonstrate the effectiveness of other possible options such as black soldier fly(BSF)and drone brood(DB)flours in FDP,with or without probiotics,as a viable substitute of milk powder during refrigerated storage for 21 days.The nutritional composition of the products remained unchanged despite the addition of insect flour,with a fat content of~0.95%and a protein content of~4.7%.The products acidity increased from 0.78%to 1.06%lactic acid during storage.The colour of the FDP was typical yellowish-white,except for those containing BSF flour which had a darker colour.For all FDP,syneresis values were below 10%after the first day of storage,particularly for those with DB flour with syneresis as low as 5%.The probiotics had the highest values of Lactobacillus spp.(>6 log CFU/g)and Streptococcus spp.(>10 log CFU/g).The addition of the BSF flour was found to have a negative impact in the consumers’perception of the products,according to the sensory analysis.展开更多
文摘Hypertension is a very prevalent risk factor for cardiovascular disease. The prevalence of resistant hypertension, i.e., uncontrolled hypertension with 3 or more antihypertensive agents including 1 diuretic, is between 5% and 30% in the hypertensive population. The causes of resistant hypertension are multifactorial and include behavioral and biological factors, such as nonadherence to pharmacological treatment. All current treatment guidelines highlight the positive role of physical exercise as a non-pharmacological tool in the treatment of hypertension. This paper draws attention to the possible role of physical exercise as an adjunct non-pharmacological tool in the management of resistant hypertension. A few studies have investigated it, employing different methodologies, and taken together they have shown promising results. In summary, the available evidence suggests that aerobic physical exercise could be a valuable addition to the optimal pharmacological treatment of patients with resistant hypertension.
基金Nuno Ribeiro would like to thank to the Portuguese Foundation of Science and Technology(FCT)for funding a PhD grant(SFRH/BD/147056/2019).
文摘Fermented dairy products(FDP)are consumed worldwide,due to their nutritional attributes and sensory properties.In the last decade,edible insects have been the subject of research as a sustainable source of protein to be introduced into the food industry.The mealworm(Tenebrio molitor)and buffalo worm(Alphitobius diaperinus)have demonstrated the highest consumer potential.However,this study aims to demonstrate the effectiveness of other possible options such as black soldier fly(BSF)and drone brood(DB)flours in FDP,with or without probiotics,as a viable substitute of milk powder during refrigerated storage for 21 days.The nutritional composition of the products remained unchanged despite the addition of insect flour,with a fat content of~0.95%and a protein content of~4.7%.The products acidity increased from 0.78%to 1.06%lactic acid during storage.The colour of the FDP was typical yellowish-white,except for those containing BSF flour which had a darker colour.For all FDP,syneresis values were below 10%after the first day of storage,particularly for those with DB flour with syneresis as low as 5%.The probiotics had the highest values of Lactobacillus spp.(>6 log CFU/g)and Streptococcus spp.(>10 log CFU/g).The addition of the BSF flour was found to have a negative impact in the consumers’perception of the products,according to the sensory analysis.