BACKGROUND Urinary tract infections(UTIs)in kidney transplant patients are a challenge.AIM To evaluate epidemiology,clinical status,therapeutic management,and clinical outcome of kidney transplant patients in a univer...BACKGROUND Urinary tract infections(UTIs)in kidney transplant patients are a challenge.AIM To evaluate epidemiology,clinical status,therapeutic management,and clinical outcome of kidney transplant patients in a university hospital for UTI.METHODS We conducted a retrospective observational study,enrolling all kidney transplant patients hospitalized for UTI,with the objective to evaluate the epidemiology,clinical status,therapeutic management,and clinical outcome of kidney transplant patients.RESULTS From our real-life experience,infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection.At the same time,the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection.CONCLUSION Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.展开更多
文摘BACKGROUND Urinary tract infections(UTIs)in kidney transplant patients are a challenge.AIM To evaluate epidemiology,clinical status,therapeutic management,and clinical outcome of kidney transplant patients in a university hospital for UTI.METHODS We conducted a retrospective observational study,enrolling all kidney transplant patients hospitalized for UTI,with the objective to evaluate the epidemiology,clinical status,therapeutic management,and clinical outcome of kidney transplant patients.RESULTS From our real-life experience,infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection.At the same time,the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection.CONCLUSION Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.
