Objective:To investigate the bioactivities of crude n-hexane,ethyl acetate and methanol extracts of aerial part of Boerhavia diffusa Linn.(B.diffusa) and its phytochemical analysis.Methods: the identification of phylo...Objective:To investigate the bioactivities of crude n-hexane,ethyl acetate and methanol extracts of aerial part of Boerhavia diffusa Linn.(B.diffusa) and its phytochemical analysis.Methods: the identification of phyloconstituents and assay of antioxidant,thrombolytic,cytotoxic, antimicrobial activities were conducted using specific standard in vitro procedures.Results:The results showed that the plant extracts were a rich source of phytoconstituents.Methanol extract showed higher antioxidant,thrombolytic activity and less cytotoxic activity than those of n-hexane and ethyl acetate extracts of A diffusa.Among the bioactivities,antioxidant activity was the most notable compared to the positive control and thus could be a potential rich source of natural antioxidant.In case of antimicrobial screening,crude extracts of the plant showed remarkable antibacterial activity against tested microorganisms.All the extracts showed significant inhibitory activity against Candida albicuns,at a concentration of 1000 μg/disc.Conclusions:The present findings suggest that,the plant widely available in Bangladesh,could be a prominent source of medicinally important natural compounds.展开更多
Objective:To establish the health benefits of Syzgium cumin to discover functional components present in the seeds,fruit pulps and fresh juice of this fruit grown in Bangladesh.Methods:Thin layer chromatography and ul...Objective:To establish the health benefits of Syzgium cumin to discover functional components present in the seeds,fruit pulps and fresh juice of this fruit grown in Bangladesh.Methods:Thin layer chromatography and ultra-violet spectroscopy were used to detect the presence of various types of compound in seeds and juice.Antioxidant effects were measured by DPPH scavenging assay and total reducing assay.Receptor binding activities was performed by hemagglutination inhibition assay.Anti-inflammatory assay and hydrogen peroxide induced hemolysis assay was also investigated.Disc diffusion assay was performed to show the antibacterial effect using Gram positive,Gram negative strains of bacteria and fungi.Results:Methanolic extract of the seeds showed stronger antioxidant,hydrogen peroxide induced hemolysis activities,hemagglutination inhibition activities and membrane stabilization activities than those of fresh juice.However,fresh juice showed stronger antibacterial and antifungal activities than those of methanolic seed extract.The seed contains higher amount of polyphenols and flavanoids than those of fruit juice.Conclusions:Therefore,fruit juice,fruit pulp and seed of Syzygium cumini contain medicinal active components in different ratios.展开更多
文摘Objective:To investigate the bioactivities of crude n-hexane,ethyl acetate and methanol extracts of aerial part of Boerhavia diffusa Linn.(B.diffusa) and its phytochemical analysis.Methods: the identification of phyloconstituents and assay of antioxidant,thrombolytic,cytotoxic, antimicrobial activities were conducted using specific standard in vitro procedures.Results:The results showed that the plant extracts were a rich source of phytoconstituents.Methanol extract showed higher antioxidant,thrombolytic activity and less cytotoxic activity than those of n-hexane and ethyl acetate extracts of A diffusa.Among the bioactivities,antioxidant activity was the most notable compared to the positive control and thus could be a potential rich source of natural antioxidant.In case of antimicrobial screening,crude extracts of the plant showed remarkable antibacterial activity against tested microorganisms.All the extracts showed significant inhibitory activity against Candida albicuns,at a concentration of 1000 μg/disc.Conclusions:The present findings suggest that,the plant widely available in Bangladesh,could be a prominent source of medicinally important natural compounds.
基金Supported by the department of Pharmacy,Fall semester 2011,East West University,Dhaka,Bangladesh.Grant No.:EWU:PHRM:FALL:2011.
文摘Objective:To establish the health benefits of Syzgium cumin to discover functional components present in the seeds,fruit pulps and fresh juice of this fruit grown in Bangladesh.Methods:Thin layer chromatography and ultra-violet spectroscopy were used to detect the presence of various types of compound in seeds and juice.Antioxidant effects were measured by DPPH scavenging assay and total reducing assay.Receptor binding activities was performed by hemagglutination inhibition assay.Anti-inflammatory assay and hydrogen peroxide induced hemolysis assay was also investigated.Disc diffusion assay was performed to show the antibacterial effect using Gram positive,Gram negative strains of bacteria and fungi.Results:Methanolic extract of the seeds showed stronger antioxidant,hydrogen peroxide induced hemolysis activities,hemagglutination inhibition activities and membrane stabilization activities than those of fresh juice.However,fresh juice showed stronger antibacterial and antifungal activities than those of methanolic seed extract.The seed contains higher amount of polyphenols and flavanoids than those of fruit juice.Conclusions:Therefore,fruit juice,fruit pulp and seed of Syzygium cumini contain medicinal active components in different ratios.
