A general and straightforward strategy for the synthesis of thioester-substituted oxindoles via a palladium-catalyzed thiocarbonyla-tive cyclization process has been developed.With sulfonyl chlorides as promising sulf...A general and straightforward strategy for the synthesis of thioester-substituted oxindoles via a palladium-catalyzed thiocarbonyla-tive cyclization process has been developed.With sulfonyl chlorides as promising sulfur source,a wide range of thioester-substituted oxindoles were obtained in moderate to high yields.Both aryl and alkyl sulfonyl chlorides were well tolerated,and Mo(CO)6 played a dual role as both a CO source and a reductant in this approach.展开更多
A palladium-catalyzed cascade Heck-type cyclization and carbonylation reaction has been developed for the synthesis of functionalized thioesters.With arylsulfonyl chlorides as odorless and readily available sulfur sou...A palladium-catalyzed cascade Heck-type cyclization and carbonylation reaction has been developed for the synthesis of functionalized thioesters.With arylsulfonyl chlorides as odorless and readily available sulfur sources,a variety of thioesters were obtained in moderate to good yields with good functional group compatibility.In this system,Mo(CO)_(6) acts as both a convenient CO surrogate and a suitable reductant.展开更多
基金We thank the financial supports from the Natural Science Foundationof Zhejiang Province(LY21B020010).
文摘A general and straightforward strategy for the synthesis of thioester-substituted oxindoles via a palladium-catalyzed thiocarbonyla-tive cyclization process has been developed.With sulfonyl chlorides as promising sulfur source,a wide range of thioester-substituted oxindoles were obtained in moderate to high yields.Both aryl and alkyl sulfonyl chlorides were well tolerated,and Mo(CO)6 played a dual role as both a CO source and a reductant in this approach.
基金We acknowledge the financial support from the Natural Science Foundation of Zhejiang Province(LY21B020010)K.C.Wong Education Foundation(GJTD-2020-08).
文摘A palladium-catalyzed cascade Heck-type cyclization and carbonylation reaction has been developed for the synthesis of functionalized thioesters.With arylsulfonyl chlorides as odorless and readily available sulfur sources,a variety of thioesters were obtained in moderate to good yields with good functional group compatibility.In this system,Mo(CO)_(6) acts as both a convenient CO surrogate and a suitable reductant.
