BACKGROUND Diabetic foot ulcers(DFUs)present a significant clinical challenge due to their high prevalence and profound impact on morbidity.Ultrasound-assisted wound debridement(UAWD)has emerged as a potential therape...BACKGROUND Diabetic foot ulcers(DFUs)present a significant clinical challenge due to their high prevalence and profound impact on morbidity.Ultrasound-assisted wound debridement(UAWD)has emerged as a potential therapeutic modality to improve healing outcomes in DFU management.AIM To evaluate the efficacy of UAWD in treating DFUs on wound closure rates,treatment duration,and quality of life outcomes.METHODS This systematic review and meta-analysis followed PRISMA guidelines,systematically searching PubMed,Embase,Web of Science,and the Cochrane Library with no date restrictions.Randomized controlled trials(RCTs)that evaluated the efficacy of UAWD in DFU treatment were included.Data were independently extracted by two reviewers,with discrepancies resolved through consensus or third-party consultation.The risk of bias was assessed using the Cochrane tool.χ2 and I2 statistics assessed heterogeneity,informing the use of fixed or random-effects models for meta-analysis,supplemented by sensitivity analysis and publication bias assessment through funnel plots and Egger's test.RESULTS From 1255 articles,seven RCTs met the inclusion criteria.The studies demonstrated that UAWD significantly reduced DFU healing time(standardized mean difference=-0.78,95%CI:-0.97 to-0.60,P<0.001)and increased healing rates(odds ratio=9.96,95%CI:5.99 to 16.56,P<0.001)compared to standard care.Sensitivity analysis confirmed the stability of these results,and no significant publication bias was detected.CONCLUSION UAWD is a promising adjunctive treatment for DFUs,significantly reducing healing times and increasing healing rates.These findings advocate for the integration of UAWD into standard DFU care protocols.展开更多
Allopolyploids often exhibit advantages in vigor and adaptability compared to diploids.A long-term goal in the economically important Brassica genus has been to develop a new allohexaploid crop type(AABBCC)by combinin...Allopolyploids often exhibit advantages in vigor and adaptability compared to diploids.A long-term goal in the economically important Brassica genus has been to develop a new allohexaploid crop type(AABBCC)by combining different diploid and allotetraploid crop species.However,early-generation allohexaploids often face challenges like unstable meiosis and low fertility,and the phenotypic performance of these synthetic lines has rarely been assessed.This study analyzes agronomic traits,fertility,and genome stability in ArArBcBcCcCc lines derived from four crosses between B.carinata and B.rapa after 9–11 selfing generations.Our results demonstrate polyploid advantage in vigor and seed traits,considerable phenotypic variation,and high fertility and genome stability.Meanwhile,parental genotypes significantly influence outcomes in advanced allohexaploids.Structural variants,largely resulting from A–C homoeologous exchanges,contribute to genomic variation and influence hexaploid genome stability,with the A sub-genome showing the highest variability.Both positive and negative impacts of SVs on fertility and seed weight are observed.Pseudo-euploids,frequently appearing,do not significantly affect fertility or other agronomic traits compared to euploids,indicating a potential pathway toward a stable allohexaploid species.These findings provide insights into the challenge and potential for developing an adaptable and stable Brassica hexaploid through selection.展开更多
Flowfield inverse design can obtain the desired flow and contour with high design efficiency,short design cycle,and small modification need.In this study,the Euler equations are formulated in the stream-function coord...Flowfield inverse design can obtain the desired flow and contour with high design efficiency,short design cycle,and small modification need.In this study,the Euler equations are formulated in the stream-function coordinates and combined with the given boundary conditions to derive a gridless space-marching method for the inverse design of subsonic,transonic,and supersonic flowfields.Designers can prescribe the flow parameters along the reference streamline to design flowfields and aerodynamic contours.The method is validated by the theoretical transonic solution,computational fluid dynamics,and experimental data,respectively.The method supports the fabrication of a Mach 2.0 single expansion tunnel.The calibration data agree well with the prescribed pressure distribution.The method is successfully applied to inverse design of contractions,nozzles,and asymmetric channels.Compared to classical analytic contractions,the contractions designed by the space-marching method provide a more accurate transonic flow.Compared to the classical Sivells’nozzle,the nozzle designed by the space-marching method provides a smaller workload,a more flexible velocity distribution,a 20%reduction in length,and an equally uniform flow.Additionally,the space-marching method is applied to design the asymmetric channels under various Mach numbers.These asymmetric channels perfectly eliminate Mach waves,achieving the shock-free flow turning and high flow uniformity.These results validate the feasibility of the space-marching method,making it a good candidate for the inverse design of subsonic,transonic,and supersonic internal flowfields and aerodynamic contours.展开更多
Southern corn leaf blight(SCLB)caused by Cochliobolus heterostrophus,is a widespread foliar disease that has a substantial impact on maize yield in the Huang-Huai-Hai Region of China.Pydiflumetofen(Pyd),a new succinat...Southern corn leaf blight(SCLB)caused by Cochliobolus heterostrophus,is a widespread foliar disease that has a substantial impact on maize yield in the Huang-Huai-Hai Region of China.Pydiflumetofen(Pyd),a new succinate dehydrogenase inhibitor(SDHI),has been found as a promising fungicide for the efficient control of SCLB,however,resistance of C.heterostrophus to Pyd has not been studied well.Here,five Pyd-resistant mutants were generated through fungicide adaptation.Sequence alignment analysis revealed that these mutants primarily mutated in ChSdhB and ChSdhD,with three genotypes:ChSdhB^(H277Y),ChSdhB^(I279T)and ChSdhD^(H133Y),exhibiting two distinct categories of resistance:high resistance(HR)and moderate resistance(MR),among which the resistance factors were 214.22 and 44.33-53.67,respectively.These mutants were more pathogenic than the wild-type parental strains,but there was a significant reduction in mycelial growth rate and sporulation in the resistant mutants,indicating a significant fitness cost associated with resistance to Pyd.In addition,this study revealed a positive cross-resistance between Pyd and another SDHI fungicide cyclobutrifluram.However,no cross-resistance was found between Pyd and other classes of fungicides,including prochloraz,fludioxonil,iprodione or pyraclostrobin.Homology modeling and molecular docking further confirmed that point mutations of ChSdhB^(H277Y),ChSdhB^(I279T),and ChSdhD^(H133Y)could reduce binding affinity between Pyd and its target subunits from-74.07,-74.07,-152.52 kcal mol^(-1)to-3.90,-4.95,-9.93 kcal mol^(-1),respectively.These findings not only provided valuable insights for managing SCLB caused by C.heterostrophus,but also enhanced our understanding of molecular mechanism underlying plant pathogen resistance to Pyd.展开更多
Objective:Deep learning(DL)has become the prevailing method in chest radiograph analysis,yet its performance heavily depends on large quantities of annotated images.To mitigate the cost,cold-start active learning(AL),...Objective:Deep learning(DL)has become the prevailing method in chest radiograph analysis,yet its performance heavily depends on large quantities of annotated images.To mitigate the cost,cold-start active learning(AL),comprising an initialization followed by subsequent learning,selects a small subset of informative data points for labeling.Recent advancements in pretrained models by supervised or self-supervised learning tailored to chest radiograph have shown broad applicability to diverse downstream tasks.However,their potential in cold-start AL remains unexplored.Methods:To validate the efficacy of domain-specific pretraining,we compared two foundation models:supervised TXRV and self-supervised REMEDIS with their general domain counterparts pretrained on ImageNet.Model performance was evaluated at both initialization and subsequent learning stages on two diagnostic tasks:psychiatric pneumonia and COVID-19.For initialization,we assessed their integration with three strategies:diversity,uncertainty,and hybrid sampling.For subsequent learning,we focused on uncertainty sampling powered by different pretrained models.We also conducted statistical tests to compare the foundation models with ImageNet counterparts,investigate the relationship between initialization and subsequent learning,examine the performance of one-shot initialization against the full AL process,and investigate the influence of class balance in initialization samples on initialization and subsequent learning.Results:First,domain-specific foundation models failed to outperform ImageNet counterparts in six out of eight experiments on informative sample selection.Both domain-specific and general pretrained models were unable to generate representations that could substitute for the original images as model inputs in seven of the eight scenarios.However,pretrained model-based initialization surpassed random sampling,the default approach in cold-start AL.Second,initialization performance was positively correlated with subsequent learning performance,highlighting the importance of initialization strategies.Third,one-shot initialization performed comparably to the full AL process,demonstrating the potential of reducing experts'repeated waiting during AL iterations.Last,a U-shaped correlation was observed between the class balance of initialization samples and model performance,suggesting that the class balance is more strongly associated with performance at middle budget levels than at low or high budgets.Conclusions:In this study,we highlighted the limitations of medical pretraining compared to general pretraining in the context of cold-start AL.We also identified promising outcomes related to cold-start AL,including initialization based on pretrained models,the positive influence of initialization on subsequent learning,the potential for one-shot initialization,and the influence of class balance on middle-budget AL.Researchers are encouraged to improve medical pretraining for versatile DL foundations and explore novel AL methods.展开更多
Emergency evacuation involves rapid transfer of individuals from hazardous areas,where limited time and space can lead to collisions.Although the collision behavior of evacuees has been studied previously,there is a l...Emergency evacuation involves rapid transfer of individuals from hazardous areas,where limited time and space can lead to collisions.Although the collision behavior of evacuees has been studied previously,there is a lack of systematic summaries.This study used the CiteSpace visualization software to analyze keywords in the evacuation collision literature.Based on the frequency of keyword occurrence,we determined the research trend;classified the keywords;and analyzed and summarized their influencing factors,behavioral characteristics,and research methods.Clearly,the evacuation environment and emergency guidance directly affect individual behavior and emotions,mainly affecting gait adjustment and decisionmaking processes,which in turn determine evacuation efficiency and collision risk.In the future,emphasis should be placed on post-collision psychological activities,coping strategies,and the application of virtual and mixed reality technologies to observe the interaction between individuals and the environment and to strengthen evacuation research.展开更多
Y chromosome microdeletions are an important cause of male infertility.At present,research on the Y chromosome is mainly focused on analyzing the loss of large segments of the azoospermia factor a/b/c(AZFa/b/c)gene,an...Y chromosome microdeletions are an important cause of male infertility.At present,research on the Y chromosome is mainly focused on analyzing the loss of large segments of the azoospermia factor a/b/c(AZFa/b/c)gene,and few studies have reported the impact of unit point deletion in the AZF band on fertility.This study analyzed the effect of sperm quality after sY1192 loss in 116 patients.The sY1192-independent deletion accounted for 41.4%(48/116).Eight patterns were found in the deletions associated with sY1192.The rate of sperm detection was similar in the semen of patients with the independent sY1192 deletion and the combined sY1192 deletions(52.1%vs 50.0%).The patients with only sY1192 gene loss had a higher probability of sperm detection than the patients whose sY1192 gene locus existed,but other gene loci were lost(52.1%vs 32.0%).The hormone levels were similar in patients with sY1192 deletion alone and in those with sY1192 deletion and other types of microdeletions in the presence of the sY1192 locus.After multiple intracytoplasmic sperm injection(ICSI)attempts,the pregnancy rate of spouses of men with sY1192-independent deletions was similar to that of other types of microdeletions,but the fertilization and cleavage rates were higher.We observed that eight deletion patterns were observed for sY1192 microdeletions of AZFb/c,dominated by the independent deletion of sY1192.After ICSI,the fertilization rate and cleavage rate of the sY1192-independent microdeletion were higher than those of other Y chromosome microdeletion types,but there was no significant difference in pregnancy outcomes.展开更多
In this paper,different stands in Xianzhong Nursery of Pingjiang were selected as the research object to study the runoff generation and soil loss characteristics of different stands.The results showed that the annual...In this paper,different stands in Xianzhong Nursery of Pingjiang were selected as the research object to study the runoff generation and soil loss characteristics of different stands.The results showed that the annual surface runoff of each model in Pingjiang was between 50.50 and 70.38 mm,and the annual surface runoff of each stand decreased with years.There was no significant difference in the annual runoff between each stand,nor between each stand and its control.There were significant differences in soil erosion modulus among the models,and the number ranged from 139.20 to 197.79 t/(km^(2)·y).展开更多
In this paper,different stands in Dongjiang Lake Reservoir area of Zixing were selected as the research objects,and the runoff generation and soil loss characteristics of different stands were studied.The results show...In this paper,different stands in Dongjiang Lake Reservoir area of Zixing were selected as the research objects,and the runoff generation and soil loss characteristics of different stands were studied.The results showed that the annual surface runoff of each model in Zixing was between 43.24 and 50.99 mm,and there was no significant difference in the annual runoff between each stand and its control.There were significant differences in soil erosion modulus among the models,and the number ranged from 127.37 to 165.58 t/(km 2·y).展开更多
Rechargeable batteries have changed human daily life from electronic devices and electric transport to renewable energy systems[1-3].Especially,lithium-ion batteries(LIBs)have dominated the market since their first co...Rechargeable batteries have changed human daily life from electronic devices and electric transport to renewable energy systems[1-3].Especially,lithium-ion batteries(LIBs)have dominated the market since their first commercialization in the 1990s,and the three pioneers(John B.Goodenough,M.Stanley Whittingham,and Akira Yoshino)in the historical development of LIBs were awarded the Novel Prize in chemistry in 2019[4].However,the imbalance between supply and demand during the past few years induced extremely huge fluctuations in lithium resources.The misgivings of lithium resources have promoted the quick development of potential alternative battery technologies.展开更多
基金Hubei Province Top Medical Youth Talent Program,Wuhan Knowledge Innovation Special Basic Research Project,No.2023020201020558Clinical Research Project of Affiliated Hospital of Guangdong Medical University,No.LCYJ2021B004 and No.LCYJ2019B010Science and Technology Plan Project of Zhanjiang,No.2022A01191.
文摘BACKGROUND Diabetic foot ulcers(DFUs)present a significant clinical challenge due to their high prevalence and profound impact on morbidity.Ultrasound-assisted wound debridement(UAWD)has emerged as a potential therapeutic modality to improve healing outcomes in DFU management.AIM To evaluate the efficacy of UAWD in treating DFUs on wound closure rates,treatment duration,and quality of life outcomes.METHODS This systematic review and meta-analysis followed PRISMA guidelines,systematically searching PubMed,Embase,Web of Science,and the Cochrane Library with no date restrictions.Randomized controlled trials(RCTs)that evaluated the efficacy of UAWD in DFU treatment were included.Data were independently extracted by two reviewers,with discrepancies resolved through consensus or third-party consultation.The risk of bias was assessed using the Cochrane tool.χ2 and I2 statistics assessed heterogeneity,informing the use of fixed or random-effects models for meta-analysis,supplemented by sensitivity analysis and publication bias assessment through funnel plots and Egger's test.RESULTS From 1255 articles,seven RCTs met the inclusion criteria.The studies demonstrated that UAWD significantly reduced DFU healing time(standardized mean difference=-0.78,95%CI:-0.97 to-0.60,P<0.001)and increased healing rates(odds ratio=9.96,95%CI:5.99 to 16.56,P<0.001)compared to standard care.Sensitivity analysis confirmed the stability of these results,and no significant publication bias was detected.CONCLUSION UAWD is a promising adjunctive treatment for DFUs,significantly reducing healing times and increasing healing rates.These findings advocate for the integration of UAWD into standard DFU care protocols.
基金supported by the Sino-German Research Project(GZ 1362)Grains Research and Development Corporation International Visiting Fellowship(UWA2406-010BGX)+1 种基金the National Natural Science Foundation of China(32171982)the Fundamental Research Funds for the Central Universities of the Chinese Government(2662023PY004).
文摘Allopolyploids often exhibit advantages in vigor and adaptability compared to diploids.A long-term goal in the economically important Brassica genus has been to develop a new allohexaploid crop type(AABBCC)by combining different diploid and allotetraploid crop species.However,early-generation allohexaploids often face challenges like unstable meiosis and low fertility,and the phenotypic performance of these synthetic lines has rarely been assessed.This study analyzes agronomic traits,fertility,and genome stability in ArArBcBcCcCc lines derived from four crosses between B.carinata and B.rapa after 9–11 selfing generations.Our results demonstrate polyploid advantage in vigor and seed traits,considerable phenotypic variation,and high fertility and genome stability.Meanwhile,parental genotypes significantly influence outcomes in advanced allohexaploids.Structural variants,largely resulting from A–C homoeologous exchanges,contribute to genomic variation and influence hexaploid genome stability,with the A sub-genome showing the highest variability.Both positive and negative impacts of SVs on fertility and seed weight are observed.Pseudo-euploids,frequently appearing,do not significantly affect fertility or other agronomic traits compared to euploids,indicating a potential pathway toward a stable allohexaploid species.These findings provide insights into the challenge and potential for developing an adaptable and stable Brassica hexaploid through selection.
基金supported by the National Key Research and Development Program of China(No.2019YFA0405300)the National Natural Science Foundation of China(No.12272405).
文摘Flowfield inverse design can obtain the desired flow and contour with high design efficiency,short design cycle,and small modification need.In this study,the Euler equations are formulated in the stream-function coordinates and combined with the given boundary conditions to derive a gridless space-marching method for the inverse design of subsonic,transonic,and supersonic flowfields.Designers can prescribe the flow parameters along the reference streamline to design flowfields and aerodynamic contours.The method is validated by the theoretical transonic solution,computational fluid dynamics,and experimental data,respectively.The method supports the fabrication of a Mach 2.0 single expansion tunnel.The calibration data agree well with the prescribed pressure distribution.The method is successfully applied to inverse design of contractions,nozzles,and asymmetric channels.Compared to classical analytic contractions,the contractions designed by the space-marching method provide a more accurate transonic flow.Compared to the classical Sivells’nozzle,the nozzle designed by the space-marching method provides a smaller workload,a more flexible velocity distribution,a 20%reduction in length,and an equally uniform flow.Additionally,the space-marching method is applied to design the asymmetric channels under various Mach numbers.These asymmetric channels perfectly eliminate Mach waves,achieving the shock-free flow turning and high flow uniformity.These results validate the feasibility of the space-marching method,making it a good candidate for the inverse design of subsonic,transonic,and supersonic internal flowfields and aerodynamic contours.
基金supported by the National Key Research and Development Program of China(2023YFD1401504)the Open Project of Anhui Province Key Laboratory of Pesticide Resistance Management on Grain and Vegetable Pests,China(PKLPRMGVP202402)+3 种基金the Programs for the Scientific Research Activities of Academic and Technical Leaders of Anhui Province,China(2020D251)the Development Fund for Talent Personnel of Anhui Agricultural University,China(rc342006)the University Synergy Innovation Program of Anhui Province,China(GXXT-2021-059)Anhui Province Agricultural Eco-Environmental Protection and Quality Safety Industry Technology System,China。
文摘Southern corn leaf blight(SCLB)caused by Cochliobolus heterostrophus,is a widespread foliar disease that has a substantial impact on maize yield in the Huang-Huai-Hai Region of China.Pydiflumetofen(Pyd),a new succinate dehydrogenase inhibitor(SDHI),has been found as a promising fungicide for the efficient control of SCLB,however,resistance of C.heterostrophus to Pyd has not been studied well.Here,five Pyd-resistant mutants were generated through fungicide adaptation.Sequence alignment analysis revealed that these mutants primarily mutated in ChSdhB and ChSdhD,with three genotypes:ChSdhB^(H277Y),ChSdhB^(I279T)and ChSdhD^(H133Y),exhibiting two distinct categories of resistance:high resistance(HR)and moderate resistance(MR),among which the resistance factors were 214.22 and 44.33-53.67,respectively.These mutants were more pathogenic than the wild-type parental strains,but there was a significant reduction in mycelial growth rate and sporulation in the resistant mutants,indicating a significant fitness cost associated with resistance to Pyd.In addition,this study revealed a positive cross-resistance between Pyd and another SDHI fungicide cyclobutrifluram.However,no cross-resistance was found between Pyd and other classes of fungicides,including prochloraz,fludioxonil,iprodione or pyraclostrobin.Homology modeling and molecular docking further confirmed that point mutations of ChSdhB^(H277Y),ChSdhB^(I279T),and ChSdhD^(H133Y)could reduce binding affinity between Pyd and its target subunits from-74.07,-74.07,-152.52 kcal mol^(-1)to-3.90,-4.95,-9.93 kcal mol^(-1),respectively.These findings not only provided valuable insights for managing SCLB caused by C.heterostrophus,but also enhanced our understanding of molecular mechanism underlying plant pathogen resistance to Pyd.
文摘Objective:Deep learning(DL)has become the prevailing method in chest radiograph analysis,yet its performance heavily depends on large quantities of annotated images.To mitigate the cost,cold-start active learning(AL),comprising an initialization followed by subsequent learning,selects a small subset of informative data points for labeling.Recent advancements in pretrained models by supervised or self-supervised learning tailored to chest radiograph have shown broad applicability to diverse downstream tasks.However,their potential in cold-start AL remains unexplored.Methods:To validate the efficacy of domain-specific pretraining,we compared two foundation models:supervised TXRV and self-supervised REMEDIS with their general domain counterparts pretrained on ImageNet.Model performance was evaluated at both initialization and subsequent learning stages on two diagnostic tasks:psychiatric pneumonia and COVID-19.For initialization,we assessed their integration with three strategies:diversity,uncertainty,and hybrid sampling.For subsequent learning,we focused on uncertainty sampling powered by different pretrained models.We also conducted statistical tests to compare the foundation models with ImageNet counterparts,investigate the relationship between initialization and subsequent learning,examine the performance of one-shot initialization against the full AL process,and investigate the influence of class balance in initialization samples on initialization and subsequent learning.Results:First,domain-specific foundation models failed to outperform ImageNet counterparts in six out of eight experiments on informative sample selection.Both domain-specific and general pretrained models were unable to generate representations that could substitute for the original images as model inputs in seven of the eight scenarios.However,pretrained model-based initialization surpassed random sampling,the default approach in cold-start AL.Second,initialization performance was positively correlated with subsequent learning performance,highlighting the importance of initialization strategies.Third,one-shot initialization performed comparably to the full AL process,demonstrating the potential of reducing experts'repeated waiting during AL iterations.Last,a U-shaped correlation was observed between the class balance of initialization samples and model performance,suggesting that the class balance is more strongly associated with performance at middle budget levels than at low or high budgets.Conclusions:In this study,we highlighted the limitations of medical pretraining compared to general pretraining in the context of cold-start AL.We also identified promising outcomes related to cold-start AL,including initialization based on pretrained models,the positive influence of initialization on subsequent learning,the potential for one-shot initialization,and the influence of class balance on middle-budget AL.Researchers are encouraged to improve medical pretraining for versatile DL foundations and explore novel AL methods.
基金Project supported by the National Natural Science Foundation of China(Grant No.52304273)Opening Fund of Key Laboratory of Civil Aviation Emergency Science&Technology(CAAC)(Grant No.NJ2022022)Fundamental Research Funds for the Central Universities(Grant No.2023XJAQ01).
文摘Emergency evacuation involves rapid transfer of individuals from hazardous areas,where limited time and space can lead to collisions.Although the collision behavior of evacuees has been studied previously,there is a lack of systematic summaries.This study used the CiteSpace visualization software to analyze keywords in the evacuation collision literature.Based on the frequency of keyword occurrence,we determined the research trend;classified the keywords;and analyzed and summarized their influencing factors,behavioral characteristics,and research methods.Clearly,the evacuation environment and emergency guidance directly affect individual behavior and emotions,mainly affecting gait adjustment and decisionmaking processes,which in turn determine evacuation efficiency and collision risk.In the future,emphasis should be placed on post-collision psychological activities,coping strategies,and the application of virtual and mixed reality technologies to observe the interaction between individuals and the environment and to strengthen evacuation research.
基金supported by the funding from the Joint Funds for the Innovation of Science and Technology,Fujian Province(Grant No.2023Y9385)Major Scientific Research Program for Young and Middleaged Health Professionals of Fujian Province,China(Grant No.2022ZQNZD010).
文摘Y chromosome microdeletions are an important cause of male infertility.At present,research on the Y chromosome is mainly focused on analyzing the loss of large segments of the azoospermia factor a/b/c(AZFa/b/c)gene,and few studies have reported the impact of unit point deletion in the AZF band on fertility.This study analyzed the effect of sperm quality after sY1192 loss in 116 patients.The sY1192-independent deletion accounted for 41.4%(48/116).Eight patterns were found in the deletions associated with sY1192.The rate of sperm detection was similar in the semen of patients with the independent sY1192 deletion and the combined sY1192 deletions(52.1%vs 50.0%).The patients with only sY1192 gene loss had a higher probability of sperm detection than the patients whose sY1192 gene locus existed,but other gene loci were lost(52.1%vs 32.0%).The hormone levels were similar in patients with sY1192 deletion alone and in those with sY1192 deletion and other types of microdeletions in the presence of the sY1192 locus.After multiple intracytoplasmic sperm injection(ICSI)attempts,the pregnancy rate of spouses of men with sY1192-independent deletions was similar to that of other types of microdeletions,but the fertilization and cleavage rates were higher.We observed that eight deletion patterns were observed for sY1192 microdeletions of AZFb/c,dominated by the independent deletion of sY1192.After ICSI,the fertilization rate and cleavage rate of the sY1192-independent microdeletion were higher than those of other Y chromosome microdeletion types,but there was no significant difference in pregnancy outcomes.
基金Supported by Hunan Forestry Science and Technology Plan(OT-S-KTA5,2024YBC15)Science and Technology Plan of Hunan Province(2021SFQ19).
文摘In this paper,different stands in Xianzhong Nursery of Pingjiang were selected as the research object to study the runoff generation and soil loss characteristics of different stands.The results showed that the annual surface runoff of each model in Pingjiang was between 50.50 and 70.38 mm,and the annual surface runoff of each stand decreased with years.There was no significant difference in the annual runoff between each stand,nor between each stand and its control.There were significant differences in soil erosion modulus among the models,and the number ranged from 139.20 to 197.79 t/(km^(2)·y).
基金Supported by Science and Technology Plan of Hunan Province(2021SFQ19)Hunan Forestry Science and Technology Plan(OT-S-KTA5,2024YBC15).
文摘In this paper,different stands in Dongjiang Lake Reservoir area of Zixing were selected as the research objects,and the runoff generation and soil loss characteristics of different stands were studied.The results showed that the annual surface runoff of each model in Zixing was between 43.24 and 50.99 mm,and there was no significant difference in the annual runoff between each stand and its control.There were significant differences in soil erosion modulus among the models,and the number ranged from 127.37 to 165.58 t/(km 2·y).
文摘Rechargeable batteries have changed human daily life from electronic devices and electric transport to renewable energy systems[1-3].Especially,lithium-ion batteries(LIBs)have dominated the market since their first commercialization in the 1990s,and the three pioneers(John B.Goodenough,M.Stanley Whittingham,and Akira Yoshino)in the historical development of LIBs were awarded the Novel Prize in chemistry in 2019[4].However,the imbalance between supply and demand during the past few years induced extremely huge fluctuations in lithium resources.The misgivings of lithium resources have promoted the quick development of potential alternative battery technologies.
