Pig bedding biochar(PBBC)and Cd-enriched Perilla frutescenswere used for joint remediation of Cd-contaminated soil.Cd-contaminated soil was treated with different concentration of PBBC.The physiological and biochemica...Pig bedding biochar(PBBC)and Cd-enriched Perilla frutescenswere used for joint remediation of Cd-contaminated soil.Cd-contaminated soil was treated with different concentration of PBBC.The physiological and biochemical indicators of P.frutescens was evaluated under different Cd stress,including biomass,antioxidant system.Meanwhile Cd bioavailability,enzyme activity and nutrient bioavailability of the soil were monitored.Results revealed that PBBC at 1%and 5%levels led to decreased diethylenetriaminepentaacetic acid-extractable Cd(DTPA-Cd)content in soil by 19.09%-20.05%and 30.10%-47.08%,respectively.Moreover,PBBC promoted the transformation of exchangeable Cd(EXC-Cd)into a more stable form,enhanced soil enzymes(peroxidase,acid phosphatase,urease,and sucrase)activities,and alleviated P.frutescens's oxidative stress.PBBC increased its biomass,consequently enhancing Cd accumulation in the plant's,thereby improving Phytoextraction rate(PER).1%PBBC showed the best effect,with a total biomass increased 21.42%-26.94%,PERwas enhanced by 39.83%-54.82%.This study justifies that the combining PBBC with P.frutescens enhances Cd removal fromsoil,making the PBBC-P.frutescens a promising choice for treating Cd-polluted soil.展开更多
Neuroendocrine neoplasms(NENs)are highly heterogeneous and potentially malignant tumors arising from secretory cells of the neuroendocrine system.Gastroenteropancreatic NENs(GEP-NENs)are the most common subtype of NEN...Neuroendocrine neoplasms(NENs)are highly heterogeneous and potentially malignant tumors arising from secretory cells of the neuroendocrine system.Gastroenteropancreatic NENs(GEP-NENs)are the most common subtype of NENs.Historically,GEP-NENs have been regarded as infrequent and slow-growing malignancies;however,recent data have demonstrated that the worldwide prevalence and incidence of GEP-NENs have increased exponentially over the last three decades.In addition,an increasing number of studies have proven that GEP-NENs result in a limited life expectancy.These findings suggested that the natural biology of GEP-NENs is more aggressive than commonly assumed.Therefore,there is an urgent need for advanced researches focusing on the diagnosis and management of patients with GEP-NENs.In this review,we have summarized the limitations and recent advancements in our comprehension of the epidemiology,clinical presentations,pathology,molecular biology,diagnosis,and treatment of GEP-NETs to identify factors contributing to delays in diagnosis and timely treatment of these patients.展开更多
Metal-organic frameworks(MOFs),a crystalline porous material with a periodic net-work structure formed by the self-assembly of transition metal ions and organic ligands,have been widely applied in various fields due t...Metal-organic frameworks(MOFs),a crystalline porous material with a periodic net-work structure formed by the self-assembly of transition metal ions and organic ligands,have been widely applied in various fields due to their rich composition and structural diversity.Among vari-ous types of MOFs,stimuli-responsive MOFs have gained increasing attention in recent years,because of their broad application in the field of physics,biology,and chemistry.In this review,we analyzed and classified the mechanism of stimulus-response MOFs(pH response,glucose response,GSH response,light response,temperature response)and their applications in drug delivery,adsorption and luminescence functions,magnetization and catalysis functions,probe and sensor.展开更多
基金supported by the Science and Technology Innovation of Fujian Agriculture and Forestry University(Nos.KFB23079 and KFB23065).
文摘Pig bedding biochar(PBBC)and Cd-enriched Perilla frutescenswere used for joint remediation of Cd-contaminated soil.Cd-contaminated soil was treated with different concentration of PBBC.The physiological and biochemical indicators of P.frutescens was evaluated under different Cd stress,including biomass,antioxidant system.Meanwhile Cd bioavailability,enzyme activity and nutrient bioavailability of the soil were monitored.Results revealed that PBBC at 1%and 5%levels led to decreased diethylenetriaminepentaacetic acid-extractable Cd(DTPA-Cd)content in soil by 19.09%-20.05%and 30.10%-47.08%,respectively.Moreover,PBBC promoted the transformation of exchangeable Cd(EXC-Cd)into a more stable form,enhanced soil enzymes(peroxidase,acid phosphatase,urease,and sucrase)activities,and alleviated P.frutescens's oxidative stress.PBBC increased its biomass,consequently enhancing Cd accumulation in the plant's,thereby improving Phytoextraction rate(PER).1%PBBC showed the best effect,with a total biomass increased 21.42%-26.94%,PERwas enhanced by 39.83%-54.82%.This study justifies that the combining PBBC with P.frutescens enhances Cd removal fromsoil,making the PBBC-P.frutescens a promising choice for treating Cd-polluted soil.
基金supported by the National Natural Science Foundation of China(82104596)the Shenzhen Key Medical Discipline Construction Fund&Sanming Project of Medicine in Shenzhen(SZSM202111002)+1 种基金the Medicine-Engineering Interdisciplinary Research Foundation of Shenzhen University(2023YG019)the Shenzhen Science and Technology Program(GJHZ20220913143005010)。
文摘Neuroendocrine neoplasms(NENs)are highly heterogeneous and potentially malignant tumors arising from secretory cells of the neuroendocrine system.Gastroenteropancreatic NENs(GEP-NENs)are the most common subtype of NENs.Historically,GEP-NENs have been regarded as infrequent and slow-growing malignancies;however,recent data have demonstrated that the worldwide prevalence and incidence of GEP-NENs have increased exponentially over the last three decades.In addition,an increasing number of studies have proven that GEP-NENs result in a limited life expectancy.These findings suggested that the natural biology of GEP-NENs is more aggressive than commonly assumed.Therefore,there is an urgent need for advanced researches focusing on the diagnosis and management of patients with GEP-NENs.In this review,we have summarized the limitations and recent advancements in our comprehension of the epidemiology,clinical presentations,pathology,molecular biology,diagnosis,and treatment of GEP-NETs to identify factors contributing to delays in diagnosis and timely treatment of these patients.
基金supported by the National Natural Science Foundation of China(U20A20388).
文摘Metal-organic frameworks(MOFs),a crystalline porous material with a periodic net-work structure formed by the self-assembly of transition metal ions and organic ligands,have been widely applied in various fields due to their rich composition and structural diversity.Among vari-ous types of MOFs,stimuli-responsive MOFs have gained increasing attention in recent years,because of their broad application in the field of physics,biology,and chemistry.In this review,we analyzed and classified the mechanism of stimulus-response MOFs(pH response,glucose response,GSH response,light response,temperature response)and their applications in drug delivery,adsorption and luminescence functions,magnetization and catalysis functions,probe and sensor.
