Hearing loss is a common health condition associated with genetic variations, diseases, loud noise exposure, and aging. Diabetes mellitus, one of the most prevalent chronic diseases, is known to increase the incidence...Hearing loss is a common health condition associated with genetic variations, diseases, loud noise exposure, and aging. Diabetes mellitus, one of the most prevalent chronic diseases, is known to increase the incidence of hearing loss in humans. However, no effective therapeutics have been developed to treat diabetes-related hearing loss (DRHL). The most evident histopathologic characteristic in the cochleae of diabetic patients is degeneration of the stria vascularis and cochlear outer hair cells (OHCs).1 For noise-induced hearing loss (NIHL), damage to hair cells is also a principal cause.2 Therefore, promoting hair cell survival would be critical for preventing DRHL and NIHL.展开更多
基金supported by the National Natural Science Foundation of China(No.32171106)the Sichuan Science and Technology Program(China)(No.2022YFS0607,2022YFS0627)+1 种基金the Joint Research Program of Luzhou City and Southwest Medical University(Sichuan,China)(No.2020LZXNYDJ21)the Science and Technology Program of Luzhou City,Sichuan,China(No.2024JYJ043).
文摘Hearing loss is a common health condition associated with genetic variations, diseases, loud noise exposure, and aging. Diabetes mellitus, one of the most prevalent chronic diseases, is known to increase the incidence of hearing loss in humans. However, no effective therapeutics have been developed to treat diabetes-related hearing loss (DRHL). The most evident histopathologic characteristic in the cochleae of diabetic patients is degeneration of the stria vascularis and cochlear outer hair cells (OHCs).1 For noise-induced hearing loss (NIHL), damage to hair cells is also a principal cause.2 Therefore, promoting hair cell survival would be critical for preventing DRHL and NIHL.
