This study investigates the width of the secondary eyewall(SE)immediately following its formation in tropical cyclones with surface environmental winds aligned and counter-aligned with environmental vertical wind shea...This study investigates the width of the secondary eyewall(SE)immediately following its formation in tropical cyclones with surface environmental winds aligned and counter-aligned with environmental vertical wind shear(VWS),using idealized numerical experiments.Results reveal that the SE develops greater radial extent when surface winds align with VWS compared to counter-aligned conditions.In alignment configurations,shear-enhanced surface winds on the right flank amplify surface enthalpy fluxes,thereby elevating boundary-layer entropy within the downshear outer-core region.Subsequently,more vigorous outer rainbands develop,inducing marked acceleration of tangential winds in the outer core preceding SE formation.The resultant radial expansion of supergradient winds near the boundary-layer top triggers widespread convective activity immediately beyond the inner core.Progressive axisymmetrization of this convective forcing ultimately generates an expansive SE structure.展开更多
This study investigates the characteristics of secondary eyewall formation(SEF)in idealized tropical cyclones embedded in vertical wind shear(VWS)at different heights.The results show that upper-layer VWS at a relativ...This study investigates the characteristics of secondary eyewall formation(SEF)in idealized tropical cyclones embedded in vertical wind shear(VWS)at different heights.The results show that upper-layer VWS at a relatively low shear height is more favorable for SEF than upper-layer VWS at a relatively high shear height and lowerlayer VWS.In the experiments with upper-layer VWS at a relatively low shear height,better-organized stratiform clouds are located in the downwind sector of outer rainbands.The low-level descending inflow associated with the stratiform sector is stronger in these experiments than in the experiments with upper-layer VWS at a relatively high shear height and lower-layer VWS.The enhanced descending inflow can trigger supergradient winds and convergence near the top of the boundary layer,close to three times the radius of the maximum wind,where convection is locally forced.The subsequent convection axisymmetrization leads to SEF.展开更多
This work investigated the effect of Na_(2)CO_(3)on the char structures of cellulose and lignin,respective-ly,and examined the electrochemi-cal performance of the char by act-ing as an active material for coin cells.T...This work investigated the effect of Na_(2)CO_(3)on the char structures of cellulose and lignin,respective-ly,and examined the electrochemi-cal performance of the char by act-ing as an active material for coin cells.The morphology of char can be significantly steered by the con-centration of Na_(2)CO_(3).Scanning electron microscopy analysis demonstrated that the intro-duction of Na_(2)CO_(3)into cellulose at an appropriate concentration led to the formation of tubular structure on its surface after pyrolysis,whereas the tubular structure was absent in the lignin char with the addition of Na_(2)CO_(3)at any concentrations.X-ray diffraction and Ra-man spectroscopy characterizations revealed that all the obtained chars from both cellulose and lignin,with or without Na_(2)CO_(3),were ascribed to non-crystalline graphite.Nevertheless,the crystal orientation of graphite from cellulose and lignin changed after the catalysis of Na_(2)CO_(3).Further electrochemical tests showed that cellulose char had a higher sodium stor-age capacity than that of lignin char.The excellent electrochemical performance of carbon materials derived from cellulose might hold a prospective application in the field of energy storage.展开更多
<strong>Objective:</strong> Explore the rule of autonomic nervous dysfunction in the patients with urination disorder after high level spinal cord injury, and seek a safe, objective and accurate method to ...<strong>Objective:</strong> Explore the rule of autonomic nervous dysfunction in the patients with urination disorder after high level spinal cord injury, and seek a safe, objective and accurate method to evaluate autonomic nervous function. <strong>Patients and Method:</strong> 48 patients with dysuria after cervicothoracic SCI were selected. Before, during and after imaging urodynamic examination with slow filling in supine position, blood pressure and ECG were monitored simultaneously. The symptoms of sweating, shivering, headache, flushing and chills were observed and recorded. The study of the relationship among the changes of blood pressure, heart rate and urodynamic indexes and the above symptoms was analyzed. <strong>Results:</strong> They were divided into three groups: group A (no obvious abnormality), group B (hyperactivity) and group C (hypoactivity) according to their BP, HR and existing the symptoms or not. <strong>Conclusion:</strong> The incidence of autonomic dysfunction in the high level SCI patients with dysuria was very high (79.17%), most of them were hyperactivity, and a few were low function. The changes of SBP and DBP in the hypoactivity group all appeared an increasing and then declining trend, while the change of HR in the low function one was lower than normal and decreased continuously. The main inducements of AD are neurogenic detrusor overactivity, detrusor sphincter dyssynergia, elevated abdominal pressure and abnormal bladder sensitivity. The asymptomatic patients had a higher occurrence rate (43.75%). Only by imaging urodynamic examination with slow filling and synchronous blood pressure monitoring, can autonomic nervous function of the patients be evaluated safely, objectively, early and accurately.展开更多
<strong>Objective:</strong> To probe into the effect of catgut implantation at Baliao and Xingfu One Acupuncture Point on dysdefecation in patients with incomplete spinal cord injury (SCI). <strong>M...<strong>Objective:</strong> To probe into the effect of catgut implantation at Baliao and Xingfu One Acupuncture Point on dysdefecation in patients with incomplete spinal cord injury (SCI). <strong>Methods:</strong> Three SCI patients voluntarily accepted catgut embedding at Baliao and Xingfu One Acupuncture point. Before and after treatment, they were filled out the self-rating scale of defecation, including the data of defecation frequency, total defecation time, defecation effort, fecal texture, fecal characteristics and fecal incontinence, etc. <strong>Results:</strong> Compared with the baseline data, constipation was improved and fecal incontinence was disappeared. <strong>Conclusions:</strong> Catgut implantation at Baliao and Xingfu One Acupuncture Point is effectual for patients with neurogenic dysporia secondary to incomplete SCI.展开更多
Coastal urban areas are prone to serious disasters caused by landfalling tropical cyclones(TCs). Despite the crucial role of urban forcing in precipitation, how fine-scale urban features impact landfalling TC precipit...Coastal urban areas are prone to serious disasters caused by landfalling tropical cyclones(TCs). Despite the crucial role of urban forcing in precipitation, how fine-scale urban features impact landfalling TC precipitation remains poorly understood. In this study, high-resolution ensemble simulations of Typhoon Rumbia(2018), which crossed the Yangtze River Delta urban agglomeration, were conducted to analyze the potential urban impact on TC precipitation. Results show that the inner-core rainfall of Rumbia is strengthened by approximately 10% due to the urban impact near the landfall,whereas minor differences in outer-core rainfall are found when the urban impact is excluded. Further diagnostic analyses indicate that low-level upward motion is crucial for precipitation evolution, as both co-vary during landfall. Moreover, the frictionally induced upward motion plays a decisive role in enhancing the rainfall when the urban impacts are included.Urban surface friction can decelerate the tangential wind and therefore destroy the gradient balance and strengthen the radial wind within the boundary layer and thus can enhance upward motion. This study demonstrates that urban surface friction and related physical processes make the most significant contribution to landfalling TC rainfall enhancement.展开更多
Objective: To explore the effect of catgut implantation at Baliao and Xingfu One Acupuncture point for patients with urinary incontinence secondary to spinal cord injury (SCI). Methods: Three SCI patients received cat...Objective: To explore the effect of catgut implantation at Baliao and Xingfu One Acupuncture point for patients with urinary incontinence secondary to spinal cord injury (SCI). Methods: Three SCI patients received catgut embedding at Baliao and Xingfu One Acupuncture point. The data of intermittent catheterization (IC) volume, intermittent catheterization frequency and the amount of using urine pad (urethral condom) were corrected. Results: Compared to the baseline data, IC volume increased and the leakage volume decreased. Conclusions: Catgut Implantation at Baliao and Xingfu One Acupuncture point is effective for patients with urinary incontinence secondary to incomplete SCI.展开更多
Ammonia(NH_(3)),a critical raw material for various industrial chemicals,is also recognized as a clean and efficient energy carrier for the future energy economy[1].However,the industrial-scale production of NH_(3) st...Ammonia(NH_(3)),a critical raw material for various industrial chemicals,is also recognized as a clean and efficient energy carrier for the future energy economy[1].However,the industrial-scale production of NH_(3) strongly relies on the Haber-Bosch process,which involves massive fuel consumption and enormous greenhouse gas emissions[2].Therefore,there is an urgent need to develop sustainable and energy-saving alternative routes for artificial NH3 production.展开更多
Introducing the inherent genetic diversity of wild species into cultivars has become one of the hot topics in crop genetic breeding and genetic resource research.Fiber-and seed-related traits,which are critical to the...Introducing the inherent genetic diversity of wild species into cultivars has become one of the hot topics in crop genetic breeding and genetic resource research.Fiber-and seed-related traits,which are critical to the global economy and people's livelihoods,are the principal focus of cotton breeding.Here,the wild cotton species Gossypium tomentosum was used to broaden the genetic basis of G.hirsutum and identify QTLs for fiber-and seed-related traits.A population of 559 chromosome segment substitution lines(CSSLs)was established with various chromosome segments from G.tomentosum in a G.hirsutum cultivar background.Totals of 72,89,and 76 QTLs were identified for three yield traits,five fiber quality traits,and six cottonseed nutrient quality traits,respectively.Favorable alleles of 104 QTLs were contributed by G.tomentosum.Sixty-four QTLs were identified in two or more environments,and candidate genes for three of them were further identified.The results of this study contribute to further studies on the genetic basis of the morphogenesis of these economic traits,and indicate the great breeding potential of G.tomentosum for improving the fiber-and seed-related traits in G.hirsutum.展开更多
In 2021,Cempaka,a tiny tropical cyclone,made landfall in China.As the TC intensified prior to landfall,the tropical cyclone size measured with precipitation decreased significantly.A numerical simulation was conducted...In 2021,Cempaka,a tiny tropical cyclone,made landfall in China.As the TC intensified prior to landfall,the tropical cyclone size measured with precipitation decreased significantly.A numerical simulation was conducted to examine the possible processes modulating the storm size.Azimuthally mean potential vorticity(PV)was found to decrease mainly in the middle to upper troposphere between 50-and 80-km radii.The PV budget results indicate that the advection and generation of mean PV associated with asymmetric processes,rather than the symmetric processes,primarily contributed to the decrease in mean PV.These asymmetric processes leading to a negative PV tendency were likely associated with inactive outer rainbands.In contrast,the tangential winds simultaneously expanded radially outward,possibly related to inner-core diabatic heating.The findings here emphasize the importance of outer rainband activity in tropical cyclone size change.展开更多
锌空气电池具有能量密度高、成本低等优点,是最具前途的绿色储能技术之一,开发用于空气阴极氧还原反应(ORR)和析氧反应(OER)的非贵金属催化剂至关重要。本文提出了一种新型高效的制备方法,通过热处理与电沉积技术,以不锈钢网为基底原位...锌空气电池具有能量密度高、成本低等优点,是最具前途的绿色储能技术之一,开发用于空气阴极氧还原反应(ORR)和析氧反应(OER)的非贵金属催化剂至关重要。本文提出了一种新型高效的制备方法,通过热处理与电沉积技术,以不锈钢网为基底原位生长NiO包裹的氮掺杂碳纳米管三维网络(NiO-CNT/SS)。得益于碳纳米管的独特三维结构,使其可以暴露出更多的活性位点,所制备催化剂OER性能优良,在100 mA cm−2电流密度下过电位仅为374 mV。此外,NiO-CNT/SS材料所组装的锌空气电池具有1.44 V开路电压以及优异的循环稳定性,在5 mA cm−2电流密度下可以稳定循环145 h而无明显衰减。展开更多
The problem of disturbance rejection in humanoid robots has been properly studied,with most prior work focusing on hip-ankle-stepping compliance control strategies or whole-body inverse dynamics control.This paper pre...The problem of disturbance rejection in humanoid robots has been properly studied,with most prior work focusing on hip-ankle-stepping compliance control strategies or whole-body inverse dynamics control.This paper presents an adaptive disturbance rejection balance controller based on a Variable-inertia Centroidal Model Predictive Control(ViC-MPC)approach,designed to address both minor disturbances that affect standing balance and major disturbances requiring stepping adjustments.The controller also facilitates reliable balance recovery after stepping adjustments.The humanoid robot is modeled as a spatial variable-inertia ellipsoid,representing the distribution of centroidal dynamics,with the contact wrenches optimized in real-time through a customized MPC formulation.Inspired by capturability-based constraints,we propose an adaptive dynamic stability transition strategy.This strategy is activated based on the Retrospective Horizon Average Centroidal Velocity(RHACV)and the Capture Point(CP),ensuring effective stepping adjustments and disturbance rejection.With the torque-controlled humanoid robot BHR8P,extensive simulation and experimental results demonstrate the effectiveness of the proposed method,highlighting its capability to adapt to and recover from various disturbances with improved stability.展开更多
A numerical simulation was performed using the Thompson microphysics scheme to preliminarily investigate the features of the microphysical processes involved in the record-breaking rainfall event that occurred in Hena...A numerical simulation was performed using the Thompson microphysics scheme to preliminarily investigate the features of the microphysical processes involved in the record-breaking rainfall event that occurred in Henan Province,China,on 20 July 2021.The simulation results showed that a strong meso-𝛾-scale vortical updraft was concurrent with the torrential rainfall.The main finding is that this event was characterized by typical midlatitude warm-rain processes.The simulation with the Thompson microphysics scheme further indicated that highly efficient collision-coalescence of cloud water to rainwater resulted in a considerably active rain droplet growth,leading to this record-breaking rainfall event.展开更多
<strong>Objective:</strong> To evaluate the efficacy and safety of Combined detrusor and external urethral sphincter BTX-A injections for detrusor overactivity (DO) and detrusor external sphincter dyssyner...<strong>Objective:</strong> To evaluate the efficacy and safety of Combined detrusor and external urethral sphincter BTX-A injections for detrusor overactivity (DO) and detrusor external sphincter dyssynergia (DESD) secondary to spinal cord injury. <strong>Study Design:</strong> Prospective study. <strong>Methods:</strong> The study was carried out in 18 SCI patients with detrusor overactivity (DO) and detrusor external sphincter dyssynergia (DESD) receiving Combined detrusor and external urethral sphincter BTX-A injections treatment. Contain 200 U botulinum toxin intradetrusor and 100 U external urethral sphincter injections. The effective outcomes included maximum detrusor pressure at first DO and DESD (PdetmaxDO-DESD), volume at first DO and DESD (VDO-DESD), maximum urethral closure pressure (MUCP), and Incontinence-Specific Quality-of-Life Instrument (I-QoL). Adverse events were recorded. <strong>Results:</strong> All patients experienced a significant mean reduction in PdetmaxDO-DESD (50.75%), maximum urethral closure pressure (26.34%) and a significant mean increase in VDO-DESD (63.00%) 12-weeks post-injection. Significant (p < 0.001) improvement in mean Incontinence-Specific Quality-of-Life Instrument was also found. No obvious adverse event and toxic effect was observed. <strong>Conclusion:</strong> Combined detrusor and external urethral sphincter BTX-A injections is a good choice for patients with DO and DESD secondary to spinal cord injury. It could not only protect the upper urinary tract but also improve quality of life.展开更多
<strong>Objective:</strong> The objective is to evaluate autonomic dysreflexia (AD) severity between urodynamics and cystoscopy in patients with spinal cord injury (SCI) above thoracic 6 (T6). <strong&g...<strong>Objective:</strong> The objective is to evaluate autonomic dysreflexia (AD) severity between urodynamics and cystoscopy in patients with spinal cord injury (SCI) above thoracic 6 (T6). <strong>Design:</strong> It is a cross-sectional survey. <strong>Subject and methods: </strong>The study was carried out in 22 patients with SCI above T6 who underwent both procedures of urodynamics and cystoscopy;all patients developed episodes of AD. The systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured and recorded at the beginning and during the various stages of the two examinations. AD was defined as a rise in SBP above 20 mm Hg. <strong>Results: </strong>There was no significant difference in SBP and DBP at baseline before urodynamics and cystoscopy. Both urodynamics and cystoscopy triggered episodes of AD. The volume of water instilled during cystoscopy was typically standard and smaller (150 mL) in comparison with urodynamics, where volume varied depending on cystometric bladder capacity (the mean bladder volume in our study was 234.86 ± 139.06 mL). The SBP was significantly different between cystoscopy and urodynamics (49.23 ± 23.07 mm Hg and 35.14 ± 15.75 mm Hg, respectively;P = 0.023). <strong>Conclusions: </strong>Although bladder distension during cystoscopy was less than that in urodynamics, the severity of AD was more pronounced during cystoscopy. It is recommended that monitoring of cardiovascular parameters during these procedures should be routinely performed.展开更多
<strong>Background: </strong>Though anticholinergic drugs are considered the standard treatment for neurogenic detrusor overactivity, it is far from an ideal tool, because of their adverse effects such as ...<strong>Background: </strong>Though anticholinergic drugs are considered the standard treatment for neurogenic detrusor overactivity, it is far from an ideal tool, because of their adverse effects such as Constipation or not respond sufficiently for a substantial proportion of patients. Recently mirabegron has become a commonly used overactive bladder medication in the general population, but few studies about mirabegron for the treatment of neurogenic detrusor overactivity. <strong>Objective:</strong> To evaluate the efficacy and safety of mirabegron for the treatment of neurogenic lower urinary tract dysfunction. <strong>Study Design:</strong> Prospective study. <strong>Methods:</strong> This prospective study included 13 adult patients with neurogenic lower urinary tract dysfunction as a result of spinal cord injury. All patients receiving mirabegron treatment (50 mg once daily) at least 6 weeks. The effective outcomes included the mean urine volume per catheterization, urinary incontinence episodes and Incontinence Specific Quality of Life Instrument. We monitored the blood pressure and heart rate to assess the cardiovascular safety, other adverse events were also recorded. <strong>Results:</strong> A total of 13 patients were included. After 6 weeks of treatment, all patients experienced a significant increase in the mean volume of per catheterization from 238.46 ± 65.43 ml to 327.69 ± 59.04 ml (p = 0.001). There is a significant reduction in the volume of urine leakage (463.85 ± 247.98 ml VS 180.00 ± 190.96 ml, p = 0.003) and incontinence episodes per 24 h (4.46 ± 2.03 VS 1.92 ± 1.50, p = 0.001). Significant improvement in mean Incontinence Specific Quality of Life Instrument was also found (p = 0.001). No patients reported dry mouth during the study, and the cardiovascular safety were acceptable. <strong>Conclusion:</strong> Mirabegron is safe and effective in the treatment of neurogenic lower urinary tract dysfunction. It might be a good choice for reducing the cessation of clean intermittent catheterization.展开更多
The additive manufacturing(AM)of Ni-based superalloys has attracted extensive interest from both academia and industry due to its unique capabilities to fabricate complex and high-performance components for use in hig...The additive manufacturing(AM)of Ni-based superalloys has attracted extensive interest from both academia and industry due to its unique capabilities to fabricate complex and high-performance components for use in high-end industrial systems.However,the intense temperature gradient induced by the rapid heating and cooling processes of AM can generate high levels of residual stress and metastable chemical and structural states,inevitably leading to severe metallurgical defects in Ni-based superalloys.Cracks are the greatest threat to these materials’integrity as they can rapidly propagate and thereby cause sudden and non-predictable failure.Consequently,there is a need for a deeper understanding of residual stress and cracking mechanisms in additively manufactured Ni-based superalloys and ways to potentially prevent cracking,as this knowledge will enable the wider application of these unique materials.To this end,this paper comprehensively reviews the residual stress and the various mechanisms of crack formation in Ni-based superalloys during AM.In addition,several common methods for inhibiting crack formation are presented to assist the research community to develop methods for the fabrication of crack-free additively manufactured components.展开更多
This retrospective study investigated the impact of endplate fracture on postoperative vertebral height loss and kyphotic deformity in 144 patients with osteoporotic vertebral compression fracture （OVCF）, who receiv...This retrospective study investigated the impact of endplate fracture on postoperative vertebral height loss and kyphotic deformity in 144 patients with osteoporotic vertebral compression fracture （OVCF）, who received balloon kyphoplasty. Patients were divided into four groups： Group 1 had no superior endplate fracture, Group 2 had fractures on the anterior portion of the superior endplate, Group 3 had fractures on the posterior portion of the superior endplate, and Group 4 had complete superior endplate fractures. Anterior and middle vertebral body height, vertebral compression ratio, vertebral height loss rate, and kyphosis Cobb angle of each patient were measured and visual analogue scale （VAS） and Oswestry disability index （ODI） scores were recorded. The anterior vertebral height and kyphosis deformity of all groups significantly improved after the surgery, whereas substantial anterior vertebral height loss and increased Cobb angle were observed in all patients at the last follow-up. Although the vertebral height loss rate and the Cobb angle in Group 2, 3 and 4 were larger compared with Group 1 at the last follow-up, only the vertebral height loss rate in Group 4 and the increase in the Cobb angle in Group 2 and 4 were statistically different from those in Group 1. The VAS and ODI scores in all groups measured after the surgery and at the last follow-up were significantly lower compared with preoperative scores, but there was no significant difference among these groups. Balloon kyphoplasty significantly improved vertebral fracture height and kyphosis. Vertebral height loss and increased kyphotic deformity were observed in OVCF patients with endplate fractures after the surgery. Postoperative aggravation of kyphosis was observed in Group 2. Furthermore, severe vertebral height loss and increased kyphotic deformity were confirmed in Group 4 after the surgery. Our results suggested that postoperative vertebral height loss and aggravation of kyphosis may be associated with biomechanical changes in the vertebral body caused by endplate fracture. Therefore, surgery should not only restore compressed vertebral body height and correct kyphosis, but also correct the deformity of endplate to achieve an effective treatment of OVCF patients with endplate fracture.展开更多
基金jointly supported by the National Natural Science Foundation of China[grant numbers U2342202,42175005,and 42175016]the Qing Lan Project[grant number R2023Q06]。
文摘This study investigates the width of the secondary eyewall(SE)immediately following its formation in tropical cyclones with surface environmental winds aligned and counter-aligned with environmental vertical wind shear(VWS),using idealized numerical experiments.Results reveal that the SE develops greater radial extent when surface winds align with VWS compared to counter-aligned conditions.In alignment configurations,shear-enhanced surface winds on the right flank amplify surface enthalpy fluxes,thereby elevating boundary-layer entropy within the downshear outer-core region.Subsequently,more vigorous outer rainbands develop,inducing marked acceleration of tangential winds in the outer core preceding SE formation.The resultant radial expansion of supergradient winds near the boundary-layer top triggers widespread convective activity immediately beyond the inner core.Progressive axisymmetrization of this convective forcing ultimately generates an expansive SE structure.
基金jointly supported by the National Natural Science Foundation of China[Grant Nos.U2342202 and 42175005]the Qing Lan Project[Grant No.R2023Q06]。
文摘This study investigates the characteristics of secondary eyewall formation(SEF)in idealized tropical cyclones embedded in vertical wind shear(VWS)at different heights.The results show that upper-layer VWS at a relatively low shear height is more favorable for SEF than upper-layer VWS at a relatively high shear height and lowerlayer VWS.In the experiments with upper-layer VWS at a relatively low shear height,better-organized stratiform clouds are located in the downwind sector of outer rainbands.The low-level descending inflow associated with the stratiform sector is stronger in these experiments than in the experiments with upper-layer VWS at a relatively high shear height and lower-layer VWS.The enhanced descending inflow can trigger supergradient winds and convergence near the top of the boundary layer,close to three times the radius of the maximum wind,where convection is locally forced.The subsequent convection axisymmetrization leads to SEF.
基金supported by Foundation Project of Jihua Laboratory(X200191TL200).
文摘This work investigated the effect of Na_(2)CO_(3)on the char structures of cellulose and lignin,respective-ly,and examined the electrochemi-cal performance of the char by act-ing as an active material for coin cells.The morphology of char can be significantly steered by the con-centration of Na_(2)CO_(3).Scanning electron microscopy analysis demonstrated that the intro-duction of Na_(2)CO_(3)into cellulose at an appropriate concentration led to the formation of tubular structure on its surface after pyrolysis,whereas the tubular structure was absent in the lignin char with the addition of Na_(2)CO_(3)at any concentrations.X-ray diffraction and Ra-man spectroscopy characterizations revealed that all the obtained chars from both cellulose and lignin,with or without Na_(2)CO_(3),were ascribed to non-crystalline graphite.Nevertheless,the crystal orientation of graphite from cellulose and lignin changed after the catalysis of Na_(2)CO_(3).Further electrochemical tests showed that cellulose char had a higher sodium stor-age capacity than that of lignin char.The excellent electrochemical performance of carbon materials derived from cellulose might hold a prospective application in the field of energy storage.
文摘<strong>Objective:</strong> Explore the rule of autonomic nervous dysfunction in the patients with urination disorder after high level spinal cord injury, and seek a safe, objective and accurate method to evaluate autonomic nervous function. <strong>Patients and Method:</strong> 48 patients with dysuria after cervicothoracic SCI were selected. Before, during and after imaging urodynamic examination with slow filling in supine position, blood pressure and ECG were monitored simultaneously. The symptoms of sweating, shivering, headache, flushing and chills were observed and recorded. The study of the relationship among the changes of blood pressure, heart rate and urodynamic indexes and the above symptoms was analyzed. <strong>Results:</strong> They were divided into three groups: group A (no obvious abnormality), group B (hyperactivity) and group C (hypoactivity) according to their BP, HR and existing the symptoms or not. <strong>Conclusion:</strong> The incidence of autonomic dysfunction in the high level SCI patients with dysuria was very high (79.17%), most of them were hyperactivity, and a few were low function. The changes of SBP and DBP in the hypoactivity group all appeared an increasing and then declining trend, while the change of HR in the low function one was lower than normal and decreased continuously. The main inducements of AD are neurogenic detrusor overactivity, detrusor sphincter dyssynergia, elevated abdominal pressure and abnormal bladder sensitivity. The asymptomatic patients had a higher occurrence rate (43.75%). Only by imaging urodynamic examination with slow filling and synchronous blood pressure monitoring, can autonomic nervous function of the patients be evaluated safely, objectively, early and accurately.
文摘<strong>Objective:</strong> To probe into the effect of catgut implantation at Baliao and Xingfu One Acupuncture Point on dysdefecation in patients with incomplete spinal cord injury (SCI). <strong>Methods:</strong> Three SCI patients voluntarily accepted catgut embedding at Baliao and Xingfu One Acupuncture point. Before and after treatment, they were filled out the self-rating scale of defecation, including the data of defecation frequency, total defecation time, defecation effort, fecal texture, fecal characteristics and fecal incontinence, etc. <strong>Results:</strong> Compared with the baseline data, constipation was improved and fecal incontinence was disappeared. <strong>Conclusions:</strong> Catgut implantation at Baliao and Xingfu One Acupuncture Point is effectual for patients with neurogenic dysporia secondary to incomplete SCI.
基金supported by the National Science Foundation of China (Grant Nos. 42088101 and 42175005)by the Postgraduate Research and Practice Innovation Program of Jiangsu Province (KYCX22_1137)。
文摘Coastal urban areas are prone to serious disasters caused by landfalling tropical cyclones(TCs). Despite the crucial role of urban forcing in precipitation, how fine-scale urban features impact landfalling TC precipitation remains poorly understood. In this study, high-resolution ensemble simulations of Typhoon Rumbia(2018), which crossed the Yangtze River Delta urban agglomeration, were conducted to analyze the potential urban impact on TC precipitation. Results show that the inner-core rainfall of Rumbia is strengthened by approximately 10% due to the urban impact near the landfall,whereas minor differences in outer-core rainfall are found when the urban impact is excluded. Further diagnostic analyses indicate that low-level upward motion is crucial for precipitation evolution, as both co-vary during landfall. Moreover, the frictionally induced upward motion plays a decisive role in enhancing the rainfall when the urban impacts are included.Urban surface friction can decelerate the tangential wind and therefore destroy the gradient balance and strengthen the radial wind within the boundary layer and thus can enhance upward motion. This study demonstrates that urban surface friction and related physical processes make the most significant contribution to landfalling TC rainfall enhancement.
文摘Objective: To explore the effect of catgut implantation at Baliao and Xingfu One Acupuncture point for patients with urinary incontinence secondary to spinal cord injury (SCI). Methods: Three SCI patients received catgut embedding at Baliao and Xingfu One Acupuncture point. The data of intermittent catheterization (IC) volume, intermittent catheterization frequency and the amount of using urine pad (urethral condom) were corrected. Results: Compared to the baseline data, IC volume increased and the leakage volume decreased. Conclusions: Catgut Implantation at Baliao and Xingfu One Acupuncture point is effective for patients with urinary incontinence secondary to incomplete SCI.
基金supported by the National Natural Science Foundation of China(51761024)“Feitian Scholar”Program of Gansu Province+1 种基金CAS“Light of West China”ProgramFoundation of A Hundred Youth Talents Training Program of Lanzhou Jiaotong University。
文摘Ammonia(NH_(3)),a critical raw material for various industrial chemicals,is also recognized as a clean and efficient energy carrier for the future energy economy[1].However,the industrial-scale production of NH_(3) strongly relies on the Haber-Bosch process,which involves massive fuel consumption and enormous greenhouse gas emissions[2].Therefore,there is an urgent need to develop sustainable and energy-saving alternative routes for artificial NH3 production.
基金supported by the National Natural Science Foundation of China(32172064)。
文摘Introducing the inherent genetic diversity of wild species into cultivars has become one of the hot topics in crop genetic breeding and genetic resource research.Fiber-and seed-related traits,which are critical to the global economy and people's livelihoods,are the principal focus of cotton breeding.Here,the wild cotton species Gossypium tomentosum was used to broaden the genetic basis of G.hirsutum and identify QTLs for fiber-and seed-related traits.A population of 559 chromosome segment substitution lines(CSSLs)was established with various chromosome segments from G.tomentosum in a G.hirsutum cultivar background.Totals of 72,89,and 76 QTLs were identified for three yield traits,five fiber quality traits,and six cottonseed nutrient quality traits,respectively.Favorable alleles of 104 QTLs were contributed by G.tomentosum.Sixty-four QTLs were identified in two or more environments,and candidate genes for three of them were further identified.The results of this study contribute to further studies on the genetic basis of the morphogenesis of these economic traits,and indicate the great breeding potential of G.tomentosum for improving the fiber-and seed-related traits in G.hirsutum.
基金jointly supported by the National Natural Science Foundation of China[grant numbers U2342202 and 42175005]the Qing Lan Project[grant number R2023Q06]。
文摘In 2021,Cempaka,a tiny tropical cyclone,made landfall in China.As the TC intensified prior to landfall,the tropical cyclone size measured with precipitation decreased significantly.A numerical simulation was conducted to examine the possible processes modulating the storm size.Azimuthally mean potential vorticity(PV)was found to decrease mainly in the middle to upper troposphere between 50-and 80-km radii.The PV budget results indicate that the advection and generation of mean PV associated with asymmetric processes,rather than the symmetric processes,primarily contributed to the decrease in mean PV.These asymmetric processes leading to a negative PV tendency were likely associated with inactive outer rainbands.In contrast,the tangential winds simultaneously expanded radially outward,possibly related to inner-core diabatic heating.The findings here emphasize the importance of outer rainband activity in tropical cyclone size change.
文摘锌空气电池具有能量密度高、成本低等优点,是最具前途的绿色储能技术之一,开发用于空气阴极氧还原反应(ORR)和析氧反应(OER)的非贵金属催化剂至关重要。本文提出了一种新型高效的制备方法,通过热处理与电沉积技术,以不锈钢网为基底原位生长NiO包裹的氮掺杂碳纳米管三维网络(NiO-CNT/SS)。得益于碳纳米管的独特三维结构,使其可以暴露出更多的活性位点,所制备催化剂OER性能优良,在100 mA cm−2电流密度下过电位仅为374 mV。此外,NiO-CNT/SS材料所组装的锌空气电池具有1.44 V开路电压以及优异的循环稳定性,在5 mA cm−2电流密度下可以稳定循环145 h而无明显衰减。
基金supported in part by the National Natural Science Foundation of China under Grant 52575004the Beijing Natural Science Foundation under Grant L243004the National Natural Science Foundation of China under Grant 62403060.
文摘The problem of disturbance rejection in humanoid robots has been properly studied,with most prior work focusing on hip-ankle-stepping compliance control strategies or whole-body inverse dynamics control.This paper presents an adaptive disturbance rejection balance controller based on a Variable-inertia Centroidal Model Predictive Control(ViC-MPC)approach,designed to address both minor disturbances that affect standing balance and major disturbances requiring stepping adjustments.The controller also facilitates reliable balance recovery after stepping adjustments.The humanoid robot is modeled as a spatial variable-inertia ellipsoid,representing the distribution of centroidal dynamics,with the contact wrenches optimized in real-time through a customized MPC formulation.Inspired by capturability-based constraints,we propose an adaptive dynamic stability transition strategy.This strategy is activated based on the Retrospective Horizon Average Centroidal Velocity(RHACV)and the Capture Point(CP),ensuring effective stepping adjustments and disturbance rejection.With the torque-controlled humanoid robot BHR8P,extensive simulation and experimental results demonstrate the effectiveness of the proposed method,highlighting its capability to adapt to and recover from various disturbances with improved stability.
基金jointly supported by the National Natural Science Foundation of China[grant numbers U2342202 and 42175005]the Qing Lan Project[grant number R2023Q06]。
文摘A numerical simulation was performed using the Thompson microphysics scheme to preliminarily investigate the features of the microphysical processes involved in the record-breaking rainfall event that occurred in Henan Province,China,on 20 July 2021.The simulation results showed that a strong meso-𝛾-scale vortical updraft was concurrent with the torrential rainfall.The main finding is that this event was characterized by typical midlatitude warm-rain processes.The simulation with the Thompson microphysics scheme further indicated that highly efficient collision-coalescence of cloud water to rainwater resulted in a considerably active rain droplet growth,leading to this record-breaking rainfall event.
文摘<strong>Objective:</strong> To evaluate the efficacy and safety of Combined detrusor and external urethral sphincter BTX-A injections for detrusor overactivity (DO) and detrusor external sphincter dyssynergia (DESD) secondary to spinal cord injury. <strong>Study Design:</strong> Prospective study. <strong>Methods:</strong> The study was carried out in 18 SCI patients with detrusor overactivity (DO) and detrusor external sphincter dyssynergia (DESD) receiving Combined detrusor and external urethral sphincter BTX-A injections treatment. Contain 200 U botulinum toxin intradetrusor and 100 U external urethral sphincter injections. The effective outcomes included maximum detrusor pressure at first DO and DESD (PdetmaxDO-DESD), volume at first DO and DESD (VDO-DESD), maximum urethral closure pressure (MUCP), and Incontinence-Specific Quality-of-Life Instrument (I-QoL). Adverse events were recorded. <strong>Results:</strong> All patients experienced a significant mean reduction in PdetmaxDO-DESD (50.75%), maximum urethral closure pressure (26.34%) and a significant mean increase in VDO-DESD (63.00%) 12-weeks post-injection. Significant (p < 0.001) improvement in mean Incontinence-Specific Quality-of-Life Instrument was also found. No obvious adverse event and toxic effect was observed. <strong>Conclusion:</strong> Combined detrusor and external urethral sphincter BTX-A injections is a good choice for patients with DO and DESD secondary to spinal cord injury. It could not only protect the upper urinary tract but also improve quality of life.
文摘<strong>Objective:</strong> The objective is to evaluate autonomic dysreflexia (AD) severity between urodynamics and cystoscopy in patients with spinal cord injury (SCI) above thoracic 6 (T6). <strong>Design:</strong> It is a cross-sectional survey. <strong>Subject and methods: </strong>The study was carried out in 22 patients with SCI above T6 who underwent both procedures of urodynamics and cystoscopy;all patients developed episodes of AD. The systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured and recorded at the beginning and during the various stages of the two examinations. AD was defined as a rise in SBP above 20 mm Hg. <strong>Results: </strong>There was no significant difference in SBP and DBP at baseline before urodynamics and cystoscopy. Both urodynamics and cystoscopy triggered episodes of AD. The volume of water instilled during cystoscopy was typically standard and smaller (150 mL) in comparison with urodynamics, where volume varied depending on cystometric bladder capacity (the mean bladder volume in our study was 234.86 ± 139.06 mL). The SBP was significantly different between cystoscopy and urodynamics (49.23 ± 23.07 mm Hg and 35.14 ± 15.75 mm Hg, respectively;P = 0.023). <strong>Conclusions: </strong>Although bladder distension during cystoscopy was less than that in urodynamics, the severity of AD was more pronounced during cystoscopy. It is recommended that monitoring of cardiovascular parameters during these procedures should be routinely performed.
文摘<strong>Background: </strong>Though anticholinergic drugs are considered the standard treatment for neurogenic detrusor overactivity, it is far from an ideal tool, because of their adverse effects such as Constipation or not respond sufficiently for a substantial proportion of patients. Recently mirabegron has become a commonly used overactive bladder medication in the general population, but few studies about mirabegron for the treatment of neurogenic detrusor overactivity. <strong>Objective:</strong> To evaluate the efficacy and safety of mirabegron for the treatment of neurogenic lower urinary tract dysfunction. <strong>Study Design:</strong> Prospective study. <strong>Methods:</strong> This prospective study included 13 adult patients with neurogenic lower urinary tract dysfunction as a result of spinal cord injury. All patients receiving mirabegron treatment (50 mg once daily) at least 6 weeks. The effective outcomes included the mean urine volume per catheterization, urinary incontinence episodes and Incontinence Specific Quality of Life Instrument. We monitored the blood pressure and heart rate to assess the cardiovascular safety, other adverse events were also recorded. <strong>Results:</strong> A total of 13 patients were included. After 6 weeks of treatment, all patients experienced a significant increase in the mean volume of per catheterization from 238.46 ± 65.43 ml to 327.69 ± 59.04 ml (p = 0.001). There is a significant reduction in the volume of urine leakage (463.85 ± 247.98 ml VS 180.00 ± 190.96 ml, p = 0.003) and incontinence episodes per 24 h (4.46 ± 2.03 VS 1.92 ± 1.50, p = 0.001). Significant improvement in mean Incontinence Specific Quality of Life Instrument was also found (p = 0.001). No patients reported dry mouth during the study, and the cardiovascular safety were acceptable. <strong>Conclusion:</strong> Mirabegron is safe and effective in the treatment of neurogenic lower urinary tract dysfunction. It might be a good choice for reducing the cessation of clean intermittent catheterization.
基金This work was supported by Shenzhen-Hong Kong Science and Technology Innovation Cooperation Zone Shenzhen Park Project:HZQB-KCZYB-2020030the National Natural Science Foundation of China(No.91860131and No.52074157)+2 种基金Guangdong Provincial Department of Science and Technology,Key-Area Research and Development Program of Guangdong Province(No.2020B090923002)the National Key Research and Development Program of China(No.2017YFB0702901)the Shenzhen Science and Technology Innovation Commission(No.JCYJ20170817111811303,No.KQTD20170328154443162and No.ZDSYS201703031748354).
文摘The additive manufacturing(AM)of Ni-based superalloys has attracted extensive interest from both academia and industry due to its unique capabilities to fabricate complex and high-performance components for use in high-end industrial systems.However,the intense temperature gradient induced by the rapid heating and cooling processes of AM can generate high levels of residual stress and metastable chemical and structural states,inevitably leading to severe metallurgical defects in Ni-based superalloys.Cracks are the greatest threat to these materials’integrity as they can rapidly propagate and thereby cause sudden and non-predictable failure.Consequently,there is a need for a deeper understanding of residual stress and cracking mechanisms in additively manufactured Ni-based superalloys and ways to potentially prevent cracking,as this knowledge will enable the wider application of these unique materials.To this end,this paper comprehensively reviews the residual stress and the various mechanisms of crack formation in Ni-based superalloys during AM.In addition,several common methods for inhibiting crack formation are presented to assist the research community to develop methods for the fabrication of crack-free additively manufactured components.
基金supported by National Natural and Science Foundation(81271988)Jiangsu Natural and Science Foundation (BK2012876)
文摘This retrospective study investigated the impact of endplate fracture on postoperative vertebral height loss and kyphotic deformity in 144 patients with osteoporotic vertebral compression fracture （OVCF）, who received balloon kyphoplasty. Patients were divided into four groups： Group 1 had no superior endplate fracture, Group 2 had fractures on the anterior portion of the superior endplate, Group 3 had fractures on the posterior portion of the superior endplate, and Group 4 had complete superior endplate fractures. Anterior and middle vertebral body height, vertebral compression ratio, vertebral height loss rate, and kyphosis Cobb angle of each patient were measured and visual analogue scale （VAS） and Oswestry disability index （ODI） scores were recorded. The anterior vertebral height and kyphosis deformity of all groups significantly improved after the surgery, whereas substantial anterior vertebral height loss and increased Cobb angle were observed in all patients at the last follow-up. Although the vertebral height loss rate and the Cobb angle in Group 2, 3 and 4 were larger compared with Group 1 at the last follow-up, only the vertebral height loss rate in Group 4 and the increase in the Cobb angle in Group 2 and 4 were statistically different from those in Group 1. The VAS and ODI scores in all groups measured after the surgery and at the last follow-up were significantly lower compared with preoperative scores, but there was no significant difference among these groups. Balloon kyphoplasty significantly improved vertebral fracture height and kyphosis. Vertebral height loss and increased kyphotic deformity were observed in OVCF patients with endplate fractures after the surgery. Postoperative aggravation of kyphosis was observed in Group 2. Furthermore, severe vertebral height loss and increased kyphotic deformity were confirmed in Group 4 after the surgery. Our results suggested that postoperative vertebral height loss and aggravation of kyphosis may be associated with biomechanical changes in the vertebral body caused by endplate fracture. Therefore, surgery should not only restore compressed vertebral body height and correct kyphosis, but also correct the deformity of endplate to achieve an effective treatment of OVCF patients with endplate fracture.
