Whether obesity is a disease or a risk factor of metabolic diseases including type 2 diabetes and fatty liver remains debating, we report here that a high-fat diet (HFD) alone or HFD-combined intramuscular injection w...Whether obesity is a disease or a risk factor of metabolic diseases including type 2 diabetes and fatty liver remains debating, we report here that a high-fat diet (HFD) alone or HFD-combined intramuscular injection with a high dose (1.2 mg/kg) of lipopolysaccharide (LPS) induces mouse peripheral noninflammatory obesity. In contrast, HFD-combined intraperitoneal injection with a low dose (0.25 mg/kg) of LPS induces mouse visceral low-grade inflammatory obesity. While the noninsulin-dependent diabetes mellitus (NIDDM) and nonalcoholic fatty liver disease (NAFLD)- related genes are globally upregulated in HFD + low-dose LPS mice, NIDDM and NAFLD genes are not extensively upregulated in HFD + high-dose LPS mice. The mitochondrial uncoupler 2,4-dini- trophenol (DNP) in the dosage of 16 mg/kg was found to exert a weight-reducing effect in obese mice by compromising NF-κB-primed inflammatory responses, thereby down regulating NIDDM and NAFLD genes. Conclusively, mouse visceral low-grade inflammatory obesity that predisposes NIDDM and NAFLD can be ameliorated by DNP via anti-inflammation.展开更多
An operator F ∈ B(X) is called power finite rank if F^n is of finite rank for some n ∈ N.In this note, we provide several interesting characterizations of power finite rank operators. In particular, we show that the...An operator F ∈ B(X) is called power finite rank if F^n is of finite rank for some n ∈ N.In this note, we provide several interesting characterizations of power finite rank operators. In particular, we show that the class of power finite rank operators is the intersection of the class of Riesz operators and the class of operators with eventual topological uniform descent.展开更多
It is shown that local spectral properties such as the single-valued extension prop- erty, Dunford＇s property （C）, Bishop＇s property （β）, the decomposition property （δ）, or de- composability are stable under...It is shown that local spectral properties such as the single-valued extension prop- erty, Dunford＇s property （C）, Bishop＇s property （β）, the decomposition property （δ）, or de- composability are stable under commuting perturbations whose spectra are finite.展开更多
文摘Whether obesity is a disease or a risk factor of metabolic diseases including type 2 diabetes and fatty liver remains debating, we report here that a high-fat diet (HFD) alone or HFD-combined intramuscular injection with a high dose (1.2 mg/kg) of lipopolysaccharide (LPS) induces mouse peripheral noninflammatory obesity. In contrast, HFD-combined intraperitoneal injection with a low dose (0.25 mg/kg) of LPS induces mouse visceral low-grade inflammatory obesity. While the noninsulin-dependent diabetes mellitus (NIDDM) and nonalcoholic fatty liver disease (NAFLD)- related genes are globally upregulated in HFD + low-dose LPS mice, NIDDM and NAFLD genes are not extensively upregulated in HFD + high-dose LPS mice. The mitochondrial uncoupler 2,4-dini- trophenol (DNP) in the dosage of 16 mg/kg was found to exert a weight-reducing effect in obese mice by compromising NF-κB-primed inflammatory responses, thereby down regulating NIDDM and NAFLD genes. Conclusively, mouse visceral low-grade inflammatory obesity that predisposes NIDDM and NAFLD can be ameliorated by DNP via anti-inflammation.
基金Supported by the Talents Cultivation Program for Outstanding Youth Scientists in Fujian Universities(Grant Nos.Min Education [2015] 54 and [2016] 23)the National Natural Science Foundation of China(Grant No.11401097)the Natural Science Foundation of Fujian Province(Grant No.2016J05001)
文摘An operator F ∈ B(X) is called power finite rank if F^n is of finite rank for some n ∈ N.In this note, we provide several interesting characterizations of power finite rank operators. In particular, we show that the class of power finite rank operators is the intersection of the class of Riesz operators and the class of operators with eventual topological uniform descent.
基金Supported by the National Natural Science Foundation of China(Grant Nos.1140109711171066+2 种基金112010711130107711301078)
文摘It is shown that local spectral properties such as the single-valued extension prop- erty, Dunford＇s property （C）, Bishop＇s property （β）, the decomposition property （δ）, or de- composability are stable under commuting perturbations whose spectra are finite.
