Cadmium(Cd)is a common environmental heavy metal pollutant known for its toxic effects on various plants and animals.Cd contamination also poses a threat to Pardosa pseudoannulata,a predator in rice paddies.Results in...Cadmium(Cd)is a common environmental heavy metal pollutant known for its toxic effects on various plants and animals.Cd contamination also poses a threat to Pardosa pseudoannulata,a predator in rice paddies.Results indicate that Cd pollution significantly reduced the levels of Metallothionein,phenoloxidase,and Ca^(2+).Furthermore,through metabolomics and 16S rDNA sequencing,alterations in the gut microbiota and immune-related metabolites of P.pseudoannulata were identified.The abundance of harmful bacteria such as Staphylococcus increased significantly,while levels of l-Tyrosine,glutathione disulfide,l-Dopa,among others,decreasedmarkedly.Pearson correlation analysis revealed significant associations between various gut microbes and immune-related metabolites,suggesting that Cd may alter the immune system of P.pseudoannulata by modulating its gut microbiota.展开更多
基金supported by the National Natural Science Foundation of China(No.42277280)the Research Foundation of the Education Bureau of Hunan Province,China(Nos.21A0048 and 22A0059)the Natural Science Foundation of Hunan Province of China(No.2022JJ50168).
文摘Cadmium(Cd)is a common environmental heavy metal pollutant known for its toxic effects on various plants and animals.Cd contamination also poses a threat to Pardosa pseudoannulata,a predator in rice paddies.Results indicate that Cd pollution significantly reduced the levels of Metallothionein,phenoloxidase,and Ca^(2+).Furthermore,through metabolomics and 16S rDNA sequencing,alterations in the gut microbiota and immune-related metabolites of P.pseudoannulata were identified.The abundance of harmful bacteria such as Staphylococcus increased significantly,while levels of l-Tyrosine,glutathione disulfide,l-Dopa,among others,decreasedmarkedly.Pearson correlation analysis revealed significant associations between various gut microbes and immune-related metabolites,suggesting that Cd may alter the immune system of P.pseudoannulata by modulating its gut microbiota.
