This paper investigates calibration of Hargreaves equation in Xiliaohe Basin. Twelve meteorologicalgauges located within Xiliaohe Basin in Northeast China were monitored during 1970 and 2014 providing continuous recor...This paper investigates calibration of Hargreaves equation in Xiliaohe Basin. Twelve meteorologicalgauges located within Xiliaohe Basin in Northeast China were monitored during 1970 and 2014 providing continuous records of meteorological data. Taking daily ET<sub>0</sub> calculated by Penman-Montieth equation as the benchmark, the error of Hargreaves equation for computing ET<sub>0</sub> was evaluated and the investigation on regional calibration of Hargreaves equation was carried out. Results showed there was an obvious difference between the calculating results of Hargreaves and Penman-Monteith equation. The estimation of the former was obviously higher during June and September while lower during the rest time in a year. The three empirical parameters of the Hargreaves equation were calibrated using the SCE-UA (Shuffled Complex Evolution) method, and the calibrated Hargreaves equation showed an obvious promotion in the accuracy both during the calibration and verification period.展开更多
This paper used the virtual reality modeling language （VRML） to establish the 3D virtual experiment instrument model, and by using the visual programming language VB to design and develop a interactive virtual reali...This paper used the virtual reality modeling language （VRML） to establish the 3D virtual experiment instrument model, and by using the visual programming language VB to design and develop a interactive virtual realization experiment platform, the interface has friendly interface, stable operation, strong practicability like with the Windows style, is a kind of reform for the traditional physics experiment teaching mode. The system has practical use value, also has reference value for the reform and modernization of other experimental courses.展开更多
Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This ...Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus.展开更多
文摘This paper investigates calibration of Hargreaves equation in Xiliaohe Basin. Twelve meteorologicalgauges located within Xiliaohe Basin in Northeast China were monitored during 1970 and 2014 providing continuous records of meteorological data. Taking daily ET<sub>0</sub> calculated by Penman-Montieth equation as the benchmark, the error of Hargreaves equation for computing ET<sub>0</sub> was evaluated and the investigation on regional calibration of Hargreaves equation was carried out. Results showed there was an obvious difference between the calculating results of Hargreaves and Penman-Monteith equation. The estimation of the former was obviously higher during June and September while lower during the rest time in a year. The three empirical parameters of the Hargreaves equation were calibrated using the SCE-UA (Shuffled Complex Evolution) method, and the calibrated Hargreaves equation showed an obvious promotion in the accuracy both during the calibration and verification period.
文摘This paper used the virtual reality modeling language （VRML） to establish the 3D virtual experiment instrument model, and by using the visual programming language VB to design and develop a interactive virtual realization experiment platform, the interface has friendly interface, stable operation, strong practicability like with the Windows style, is a kind of reform for the traditional physics experiment teaching mode. The system has practical use value, also has reference value for the reform and modernization of other experimental courses.
基金supported by the National Natural Science Foundation of China(81270897,81300668,81370939,81400813,81400808,81530026,81370922)the Jiangsu Provincial Special Program of Medical Science(BL2012026)the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions support this study
文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus.
