Rheumatoid arthritis(RA)is a prevalent and debilitating inflammatory disease that significantly impairs functional capacity and quality of life.RA accelerates musculoskeletal aging,leading to complications such as mus...Rheumatoid arthritis(RA)is a prevalent and debilitating inflammatory disease that significantly impairs functional capacity and quality of life.RA accelerates musculoskeletal aging,leading to complications such as muscle degeneration and sarcopenia.Recent research has identified myopenia as a condition of significant muscle loss associated with illness,distinct from the muscle wasting seen in other chronic diseases like cancer cachexia or heart failure.In RA,myopenia is characterized by muscle depletion without concurrent significant fat loss,and it can affect individuals of all ages.While inflammation plays a central role,it is not the sole factor contributing to the high incidence of muscle wasting in RA.In subsequent discussions,secondary sarcopenia will be considered alongside myopenia,as both involve muscle wasting decline primarily due to disease.This review summarizes recent findings on the impact of RA-related myopenia and secondary sarcopenia on functional capacity,explores its underlying mechanisms,and discusses contemporary strategies to mitigate the process of musculoskeletal aging in RA patients.展开更多
The alkaline anion exchange membrane(AEM)water electrolysis technology has advantages of low cost,high current density,and fast dynamic response,and it has attracted more attention from researchers in the last few yea...The alkaline anion exchange membrane(AEM)water electrolysis technology has advantages of low cost,high current density,and fast dynamic response,and it has attracted more attention from researchers in the last few years.As one of the core components in this water electrolysis technology,AEMs play a crucial role in improving the hydrogen production efficiency of electrolyzers.However,it is difficult to achieve high ionic conductivity and high alkaline stability of AEMs simultaneously,which limits the practical applications of this hydrogen production technology.This review focuses on alkaline AEMs,which can be applied in the field of water electrolysis.Firstly,the performance evaluation system and the structure-activity relationship of AEMs are proposed.Then,the research progress of AEMs for water electrolysis was illustrated in detail.Finally,the current challenges and outlooks for development of AEMs applied in water electrolysis are presented.We hope this review can provide a new perspective for the design and preparation of AEMs for the demand of practical applications in water electrolysis.展开更多
The increasing emission of carbon dioxide(CO_(2))has intensified global efforts toward its conversion and utilization.Electrocatalytic CO_(2)reduction reaction(CO_(2)RR)has emerged as a promising sustainable strategy ...The increasing emission of carbon dioxide(CO_(2))has intensified global efforts toward its conversion and utilization.Electrocatalytic CO_(2)reduction reaction(CO_(2)RR)has emerged as a promising sustainable strategy to address interconnected energy and environmental challenges.Among the various products of CO_(2)reduction,methanol has attracted significant research attention as both an essential chemical feedstock and a promising renewable energy carrier.This review comprehensively summarizes recent advances in the electrocatalytic conversion of CO_(2)to methanol,with systematic discussions on fundamental reaction mechanisms and pathways,innovative reactor configurations,diverse catalysts,and auxiliary optimization strategies.Particular emphasis is placed on categorizing and evaluating various catalysts,including mono-/bimetallic catalysts,molecular catalysts,enzyme catalysts,and carbon-based materials,while exploring their structure-activity relationships and performance enhancement strategies for improving methanol selectivity.Furthermore,the techno-economic viability of current processes is analyzed,assessing the cost-effectiveness and commercial potential of electrocatalytic methanol production.Finally,based on current research progress and existing challenges,key research directions are outlined to advance the development of commercially feasible electrocatalytic CO_(2)-to-methanol systems,providing practical guidance for future investigations.展开更多
The lithium redox at the Li/electrolyte interface have significantlyinfluenceson the road achieving high performance lithium metal anode(LMA).Lithium dendrite formation caused by inhomogeneous Li deposition at Li/elec...The lithium redox at the Li/electrolyte interface have significantlyinfluenceson the road achieving high performance lithium metal anode(LMA).Lithium dendrite formation caused by inhomogeneous Li deposition at Li/electrolyte interface is one of the critical challenges for rechargeable Li metal batteries(LMBs).Besides,the incompatibility of commonly used commercial ester-based electrolytes with metallic lithium also limits the application of LMA,while some reported additives can only maintain their efficiencyin ether-based electrolytes.In this work,2-Mercaptopyridine(2Mpy),which we have proposed in ether-based electrolyte application,is introduced into commercial ester-based electrolyte as a redox promoter and the evolution of Li deposition and the mechanism of additive has been further investigated.The redox of Li+/Li is accelerated and the cycling performances of LMBs in ester-based electrolyte are greatly improved with 2Mpy participated.This work further demonstrates the effectiveness of charge transfer mediator additives such as 2Mpy in ester-based electrolyte,opening up a practical path to achieving high-performance additive for lithium metal batteries.展开更多
Lithium is known as the“white petroleum”of the electrification era,and the global demand for lithium grows rapidly with the quick development of new energy industry.The aqueous solutions,such as salt lake brine,unde...Lithium is known as the“white petroleum”of the electrification era,and the global demand for lithium grows rapidly with the quick development of new energy industry.The aqueous solutions,such as salt lake brine,underground brine,and seawater,have large lithium reserves,thus this kind of lithium resource has become a research hotspot recently.Compared with other lithium extraction technologies,electro-sorption method shows good prospects for practical applications with advantages in the aspects of efficiency,recovery ratio,cost,and environment.Herein,this review covers recent progress on electro-sorption technology for lithium recovery from aqueous solutions,including the concept illustration,research progress of the applied working electrodes and counter electrodes,and the evaluation indicators of electro-sorption system.Meanwhile,some prospects for the development of this technology are also proposed.We hope this review is beneficial for the construction of high-efficient electrochemical lithium recovery system to achieve an adequate lithium supply in the future.展开更多
基金supported in part by the National Natural Science Foundation of China(Grant No.82350710800,82374470,82202757)Shenzhen Medical Research Fund B2302005,and NHMRC,APP1163933.
文摘Rheumatoid arthritis(RA)is a prevalent and debilitating inflammatory disease that significantly impairs functional capacity and quality of life.RA accelerates musculoskeletal aging,leading to complications such as muscle degeneration and sarcopenia.Recent research has identified myopenia as a condition of significant muscle loss associated with illness,distinct from the muscle wasting seen in other chronic diseases like cancer cachexia or heart failure.In RA,myopenia is characterized by muscle depletion without concurrent significant fat loss,and it can affect individuals of all ages.While inflammation plays a central role,it is not the sole factor contributing to the high incidence of muscle wasting in RA.In subsequent discussions,secondary sarcopenia will be considered alongside myopenia,as both involve muscle wasting decline primarily due to disease.This review summarizes recent findings on the impact of RA-related myopenia and secondary sarcopenia on functional capacity,explores its underlying mechanisms,and discusses contemporary strategies to mitigate the process of musculoskeletal aging in RA patients.
基金financially supported by the China Huaneng Group Found Project(Nos.HNKJ24-H12,HNKJ22-H130,HNKJ21-H07,and HNKJ24-H13)the Huaneng Clean Energy Research Institute Found Project(Nos.TL-22-CERI01 and CERI/TU-23-CERI03).
文摘The alkaline anion exchange membrane(AEM)water electrolysis technology has advantages of low cost,high current density,and fast dynamic response,and it has attracted more attention from researchers in the last few years.As one of the core components in this water electrolysis technology,AEMs play a crucial role in improving the hydrogen production efficiency of electrolyzers.However,it is difficult to achieve high ionic conductivity and high alkaline stability of AEMs simultaneously,which limits the practical applications of this hydrogen production technology.This review focuses on alkaline AEMs,which can be applied in the field of water electrolysis.Firstly,the performance evaluation system and the structure-activity relationship of AEMs are proposed.Then,the research progress of AEMs for water electrolysis was illustrated in detail.Finally,the current challenges and outlooks for development of AEMs applied in water electrolysis are presented.We hope this review can provide a new perspective for the design and preparation of AEMs for the demand of practical applications in water electrolysis.
基金supported by the National Key Laboratory of High-Efficiency Flexible Coal Power Generation and Carbon Capture Utilization and Storage and China Huaneng Group,China(Grant No.HNKJ24-H13)。
文摘The increasing emission of carbon dioxide(CO_(2))has intensified global efforts toward its conversion and utilization.Electrocatalytic CO_(2)reduction reaction(CO_(2)RR)has emerged as a promising sustainable strategy to address interconnected energy and environmental challenges.Among the various products of CO_(2)reduction,methanol has attracted significant research attention as both an essential chemical feedstock and a promising renewable energy carrier.This review comprehensively summarizes recent advances in the electrocatalytic conversion of CO_(2)to methanol,with systematic discussions on fundamental reaction mechanisms and pathways,innovative reactor configurations,diverse catalysts,and auxiliary optimization strategies.Particular emphasis is placed on categorizing and evaluating various catalysts,including mono-/bimetallic catalysts,molecular catalysts,enzyme catalysts,and carbon-based materials,while exploring their structure-activity relationships and performance enhancement strategies for improving methanol selectivity.Furthermore,the techno-economic viability of current processes is analyzed,assessing the cost-effectiveness and commercial potential of electrocatalytic methanol production.Finally,based on current research progress and existing challenges,key research directions are outlined to advance the development of commercially feasible electrocatalytic CO_(2)-to-methanol systems,providing practical guidance for future investigations.
基金supported by China Huaneng Group Technology Project(HNKJ24-HF16).
文摘The lithium redox at the Li/electrolyte interface have significantlyinfluenceson the road achieving high performance lithium metal anode(LMA).Lithium dendrite formation caused by inhomogeneous Li deposition at Li/electrolyte interface is one of the critical challenges for rechargeable Li metal batteries(LMBs).Besides,the incompatibility of commonly used commercial ester-based electrolytes with metallic lithium also limits the application of LMA,while some reported additives can only maintain their efficiencyin ether-based electrolytes.In this work,2-Mercaptopyridine(2Mpy),which we have proposed in ether-based electrolyte application,is introduced into commercial ester-based electrolyte as a redox promoter and the evolution of Li deposition and the mechanism of additive has been further investigated.The redox of Li+/Li is accelerated and the cycling performances of LMBs in ester-based electrolyte are greatly improved with 2Mpy participated.This work further demonstrates the effectiveness of charge transfer mediator additives such as 2Mpy in ester-based electrolyte,opening up a practical path to achieving high-performance additive for lithium metal batteries.
基金supported by Huaneng Clean Energy Research Institute Found Project(No.CERI/TU-23-CERI03).
文摘Lithium is known as the“white petroleum”of the electrification era,and the global demand for lithium grows rapidly with the quick development of new energy industry.The aqueous solutions,such as salt lake brine,underground brine,and seawater,have large lithium reserves,thus this kind of lithium resource has become a research hotspot recently.Compared with other lithium extraction technologies,electro-sorption method shows good prospects for practical applications with advantages in the aspects of efficiency,recovery ratio,cost,and environment.Herein,this review covers recent progress on electro-sorption technology for lithium recovery from aqueous solutions,including the concept illustration,research progress of the applied working electrodes and counter electrodes,and the evaluation indicators of electro-sorption system.Meanwhile,some prospects for the development of this technology are also proposed.We hope this review is beneficial for the construction of high-efficient electrochemical lithium recovery system to achieve an adequate lithium supply in the future.
