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Positional Information is a Strong Supervision for Volumetric Medical Image Segmentation
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作者 ZHAO Yinjie HOU Runping +5 位作者 ZENG Wanqin qin yulei SHEN Tianle XU Zhiyong FU Xiaolong SHEN Hongbin 《Journal of Shanghai Jiaotong university(Science)》 2025年第1期121-129,共9页
Medical image segmentation is a crucial preliminary step for a number of downstream diagnosis tasks.As deep convolutional neural networks successfully promote the development of computer vision,it is possible to make ... Medical image segmentation is a crucial preliminary step for a number of downstream diagnosis tasks.As deep convolutional neural networks successfully promote the development of computer vision,it is possible to make medical image segmentation a semi-automatic procedure by applying deep convolutional neural networks to finding the contours of regions of interest that are then revised by radiologists.However,supervised learning necessitates large annotated data,which are difficult to acquire especially for medical images.Self-supervised learning is able to take advantage of unlabeled data and provide good initialization to be finetuned for downstream tasks with limited annotations.Considering that most self-supervised learning especially contrastive learning methods are tailored to natural image classification and entail expensive GPU resources,we propose a novel and simple pretext-based self-supervised learning method that exploits the value of positional information in volumetric medical images.Specifically,we regard spatial coordinates as pseudo labels and pretrain the model by predicting positions of randomly sampled 2D slices in volumetric medical images.Experiments on four semantic segmentation datasets demonstrate the superiority of our method over other self-supervised learning methods in both semi-supervised learning and transfer learning settings.Codes are available at https://github.com/alienzyj/PPos. 展开更多
关键词 self-supervised learning medical image analysis semantic segmentation
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血清白介素-6、D-二聚体、降钙素原在重症肺炎机械通气患者中表达意义及预后评估价值
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作者 骆岚 邓彬 +5 位作者 刘海波 程靖 许健 覃雨雷 罗丹 朱灿 《晓庄学院学报(医学版)》 2025年第1期144-149,共6页
目的:分析血清白介素-6(interleukin,IL)、D-二聚体(D-dimer,D-D)、降钙素原(procalcitonin,PCT)在重症肺炎机械通气患者中的临床表达意义及预后评估中的价值。方法:使用回顾性分析法,将2022年12月—2024年10月我院接收的280例重症肺炎... 目的:分析血清白介素-6(interleukin,IL)、D-二聚体(D-dimer,D-D)、降钙素原(procalcitonin,PCT)在重症肺炎机械通气患者中的临床表达意义及预后评估中的价值。方法:使用回顾性分析法,将2022年12月—2024年10月我院接收的280例重症肺炎行机械通气患者纳入病例组,另择取90例健康体检者作为健康组,采用COX比例风险回归模型患者预后的单因素和多因素分析。通过随访获取患者的预后信息,采用受试者工作特征曲线(receiver operating characteristic curve,ROC)分析血清IL-6、D-D、PCT联合检测对重症肺炎机械通气患者死亡的预测价值。结果:病例组患者血清IL-6、D-D、PCT表达水平明显高于健康组。随访时间为13(7,14)d,280例重症肺炎机械通气患者中死亡例30例(10.71)%,存活250例(89.29)%,中位OS时间9(7,11)d。单因素分析结果显示,年龄、IL-6、D-D、PCT、氧合指数(PaO2/FiO2)均与重症肺炎机械通气患者不良预后有关。COX多因素回归分析结果显示,年龄、IL-6、D-D、PCT均是重症肺炎机械通气患者不良预后的独立危险因素,氧合指数(PaO2/FiO2)是其保护因素。ROC曲线显示,血清IL-6、D-D、PCT单项指标预测重症肺炎机械通气患者不良预后的AUC、敏感度、特异度分别为(0.738、0.903、0.839;76.7%、86.7%、83.3%;70.4%、74.0%、72.8%),均低于三项指标联合预测的AUC、敏感度(0.955、96.7%、89.2%)。结论:COX比例风险模型分析显示,血清IL-6、D-D、PCT是重症肺炎机械通气患者预后评估指标。血清IL-6、D-D、PCT在重症肺炎机械通气患者中表达升高,与病情严重程度密切相关,联合检测对预后评估具有重要价值。 展开更多
关键词 重症肺炎 机械通气 白细胞介素-6 D-二聚体 降钙素原 预后评估价值
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