BACKGROUND Functional gastrointestinal disorders(FGIDs),defined as‘Disorders of Gut-Brain Interaction’,are now considered a global health problem.There is a dearth of concepts and scales to assess the severity of th...BACKGROUND Functional gastrointestinal disorders(FGIDs),defined as‘Disorders of Gut-Brain Interaction’,are now considered a global health problem.There is a dearth of concepts and scales to assess the severity of the different symptoms encountered while dealing with the variety of FGIDs as described in the ROME IV classi-fication.We introduced a novel scoring system with the incorporation of 16 different symptoms called Bacharyya’s Questionnaire Scale and started using it while dealing with children suffering from FGIDs.AIM To verify the usefulness and applicability of this recently developed scale,this study was undertaken with the objectives to establish the validity of this scoring system in assessing the severity of symptoms associated with a specific FGID in children and to determine the scoring system's applicability in assessing the treatment response.METHODS The study included children aged 5 to 18 years diagnosed with any FGID based on ROME IV criteria.They completed the newly developed scale and a Visual Analog Scale at initial diagnosis and after a 2-month treatment period.A control group without FGID participated for comparative baseline purposes.Treatment response was defined as a less than or equal to 50%reduction in the total score,which is statistically significant.RESULTS Results from a comprehensive cohort of 190 cases and 90 controls indicated a female preponderance(57.9%)and prevalent disorders such as functional constipation(28%)and functional abdominal pain,not otherwise specified(21%).The grade of FGID(mild,moderate,severe)experienced by the patients was also derived.Post-treatment,96 children demonstrated symptom improvement.The Spearman rank correlation coefficient for pre(r=0.72,95%CI:0.65-0.77,P value<0.0001)and post(r=0.49,95%CI:0.3-0.64,P value<0.0001)treatment data showed positive results with significant P values.CONCLUSION The novel scoring system shows high comprehensibility and gives an objective view of the symptomatology of FGIDs.The use of this novel score in clinical settings will be helpful to typify the FGIDs and may significantly improve decision-making processes to initiate appropriate treatment.展开更多
This paper deals with control of chaotic behavior of a delayed Cellular Neural Network (DCNN) model which is a one-dimensional regular array of four cells with continuous activation function. We investigate different ...This paper deals with control of chaotic behavior of a delayed Cellular Neural Network (DCNN) model which is a one-dimensional regular array of four cells with continuous activation function. We investigate different dynamical behaviors including limit cycle, torus, and chaos for different range of weight parameters of the system. Regarding synaptic weight as parameter, Hopf bifurcations are obtained in the system without delay. In the delayed model condition for the Global asymptotic stability of the equilibrium point is presented. Numerical simulation and results are given to show the role of delay in chaos control of the CNNs.展开更多
Economic indicators are snippets of financial and economic data published regularly by governmental agencies and the private sector. An exchange rate represents the value of one currency in another and it fluctuates o...Economic indicators are snippets of financial and economic data published regularly by governmental agencies and the private sector. An exchange rate represents the value of one currency in another and it fluctuates over time. ForEx rates are affected by many highly correlated economic, political and even psychological factors. It was observed that changes in the exchange rate are related to news in the fundamentals which cover Inflation for the country concerned. In a series of work, we investigated and confirmed the chaotic property of ForEx Rates of several countries. In this perspective, we concentrate on nonlinear data analysis of inflation data of nine countries. We find existence of chaos in inflation data for some countries.展开更多
文摘BACKGROUND Functional gastrointestinal disorders(FGIDs),defined as‘Disorders of Gut-Brain Interaction’,are now considered a global health problem.There is a dearth of concepts and scales to assess the severity of the different symptoms encountered while dealing with the variety of FGIDs as described in the ROME IV classi-fication.We introduced a novel scoring system with the incorporation of 16 different symptoms called Bacharyya’s Questionnaire Scale and started using it while dealing with children suffering from FGIDs.AIM To verify the usefulness and applicability of this recently developed scale,this study was undertaken with the objectives to establish the validity of this scoring system in assessing the severity of symptoms associated with a specific FGID in children and to determine the scoring system's applicability in assessing the treatment response.METHODS The study included children aged 5 to 18 years diagnosed with any FGID based on ROME IV criteria.They completed the newly developed scale and a Visual Analog Scale at initial diagnosis and after a 2-month treatment period.A control group without FGID participated for comparative baseline purposes.Treatment response was defined as a less than or equal to 50%reduction in the total score,which is statistically significant.RESULTS Results from a comprehensive cohort of 190 cases and 90 controls indicated a female preponderance(57.9%)and prevalent disorders such as functional constipation(28%)and functional abdominal pain,not otherwise specified(21%).The grade of FGID(mild,moderate,severe)experienced by the patients was also derived.Post-treatment,96 children demonstrated symptom improvement.The Spearman rank correlation coefficient for pre(r=0.72,95%CI:0.65-0.77,P value<0.0001)and post(r=0.49,95%CI:0.3-0.64,P value<0.0001)treatment data showed positive results with significant P values.CONCLUSION The novel scoring system shows high comprehensibility and gives an objective view of the symptomatology of FGIDs.The use of this novel score in clinical settings will be helpful to typify the FGIDs and may significantly improve decision-making processes to initiate appropriate treatment.
文摘This paper deals with control of chaotic behavior of a delayed Cellular Neural Network (DCNN) model which is a one-dimensional regular array of four cells with continuous activation function. We investigate different dynamical behaviors including limit cycle, torus, and chaos for different range of weight parameters of the system. Regarding synaptic weight as parameter, Hopf bifurcations are obtained in the system without delay. In the delayed model condition for the Global asymptotic stability of the equilibrium point is presented. Numerical simulation and results are given to show the role of delay in chaos control of the CNNs.
文摘Economic indicators are snippets of financial and economic data published regularly by governmental agencies and the private sector. An exchange rate represents the value of one currency in another and it fluctuates over time. ForEx rates are affected by many highly correlated economic, political and even psychological factors. It was observed that changes in the exchange rate are related to news in the fundamentals which cover Inflation for the country concerned. In a series of work, we investigated and confirmed the chaotic property of ForEx Rates of several countries. In this perspective, we concentrate on nonlinear data analysis of inflation data of nine countries. We find existence of chaos in inflation data for some countries.
