Objective:To describe the dynamic contrast-enhanced CT(DCECT)appearance of pulmonary nodules related to infection with coccidioidomycosis.Methods Retrospective review of a database of DCECTs identified a subset of pat...Objective:To describe the dynamic contrast-enhanced CT(DCECT)appearance of pulmonary nodules related to infection with coccidioidomycosis.Methods Retrospective review of a database of DCECTs identified a subset of patients with pulmonary nodules related to coccidioidomycosis.General and DCECT imaging characteristics of these nodules were evaluated.Results 16 of the 44 nodules identified(36.4%)showed enhancement on DCECT imaging.The majority(74.9%)of enhancing nodules demonstrate delayed(3 or 4 min)peak enhancement.The majority(88.6%)of the 44 nodules were either smooth or lobulated in appearance.Only 1(2.3%)of the nodules was cavitary.19(43.2%)of the nodules had adjacent satellite nodules.DCECT can be a useful study to help characterize pulmonary nodules in areas with endemic Coccidioides with an expected false-positive rate of∼30–40%.Biopsy could potentially be averted in 60–70%of nodules by evaluating with DCECT prior to tissue sampling.Conclusion When combined with morphological,serological,clinical,and historical information DCECT can be a powerful tool for reducing the number of benign nodules being biopsied and/or resected.展开更多
Introduction Pulmonary Aspergillus infection can manifest as a variety of forms depending on the patients underlying immune status,the load of the organisms and the underlying condition of the lungs.Discussion Hyperse...Introduction Pulmonary Aspergillus infection can manifest as a variety of forms depending on the patients underlying immune status,the load of the organisms and the underlying condition of the lungs.Discussion Hypersensitivity pneumonitis and allergic bronchopulmonary Aspergillosis(ABPA)are typically seen in patients with hyper-immune status(asthma,atopy and hyper-eosinophilia).Aspergilloma or mycetoma is seen in patients with preexisting lung damage and cavities commonly from prior TB or sarcoidosis.In patients with immunosuppression,Aspergillus infection can present as semi-invasive or invasive(angioinvasive and airway invasive)aspergillosis.Conclusion In this article we correlate the radiologic findings of the various pulmonary manifestations of Aspergillus infection with their pathologic features to better understand the disease process and better comprehend the associated imaging patterns.展开更多
文摘Objective:To describe the dynamic contrast-enhanced CT(DCECT)appearance of pulmonary nodules related to infection with coccidioidomycosis.Methods Retrospective review of a database of DCECTs identified a subset of patients with pulmonary nodules related to coccidioidomycosis.General and DCECT imaging characteristics of these nodules were evaluated.Results 16 of the 44 nodules identified(36.4%)showed enhancement on DCECT imaging.The majority(74.9%)of enhancing nodules demonstrate delayed(3 or 4 min)peak enhancement.The majority(88.6%)of the 44 nodules were either smooth or lobulated in appearance.Only 1(2.3%)of the nodules was cavitary.19(43.2%)of the nodules had adjacent satellite nodules.DCECT can be a useful study to help characterize pulmonary nodules in areas with endemic Coccidioides with an expected false-positive rate of∼30–40%.Biopsy could potentially be averted in 60–70%of nodules by evaluating with DCECT prior to tissue sampling.Conclusion When combined with morphological,serological,clinical,and historical information DCECT can be a powerful tool for reducing the number of benign nodules being biopsied and/or resected.
文摘Introduction Pulmonary Aspergillus infection can manifest as a variety of forms depending on the patients underlying immune status,the load of the organisms and the underlying condition of the lungs.Discussion Hypersensitivity pneumonitis and allergic bronchopulmonary Aspergillosis(ABPA)are typically seen in patients with hyper-immune status(asthma,atopy and hyper-eosinophilia).Aspergilloma or mycetoma is seen in patients with preexisting lung damage and cavities commonly from prior TB or sarcoidosis.In patients with immunosuppression,Aspergillus infection can present as semi-invasive or invasive(angioinvasive and airway invasive)aspergillosis.Conclusion In this article we correlate the radiologic findings of the various pulmonary manifestations of Aspergillus infection with their pathologic features to better understand the disease process and better comprehend the associated imaging patterns.
