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Nuclear data measurement and propagation in Back-n experiments:methodologies and instrumentation
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作者 Min-Hao Gu Jie-Ming Xue +7 位作者 Ya-Kang Li ping cao Jie Ren Yong-Hao Chen Wei Jiang Han Yi Peng Hu Rui-Rui Fan 《Nuclear Science and Techniques》 2025年第11期69-82,共14页
This article introduces the methodologies and instrumentation for data measurement and propagation at the Back-n white neutron facility of the China Spallation Neutron Source.The Back-n facility employs backscattering... This article introduces the methodologies and instrumentation for data measurement and propagation at the Back-n white neutron facility of the China Spallation Neutron Source.The Back-n facility employs backscattering techniques to generate a broad spectrum of white neutrons.Equipped with advanced detectors such as the light particle detector array and the fission ionization chamber detector,the facility achieves high-precision data acquisition through a general-purpose electronics system.Data were managed and stored in a hierarchical system supported by the National High Energy Physics Science Data Center,ensuring long-term preservation and efficient access.The data from the Back-n experiments significantly contribute to nuclear physics,reactor design,astrophysics,and medical physics,enhancing the understanding of nuclear processes and supporting interdisciplinary research. 展开更多
关键词 Nuclear physics Data acquisition Data storage and management Data sharing Neutron experiments White neutron beam
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Treatment of Single Level Lumbar Spondylolisthesis with Lumbar Interbody Fusion via Oblique Lateral Approach (OLIF) 被引量:1
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作者 Jinpeng Zheng Dun Liu +3 位作者 Jing Shi Han Wu ping cao Bing Hu 《Surgical Science》 2023年第1期46-54,共9页
Objectives: To investigate the effect of lumbar interbody fusion via the oblique lateral approach (OLIF) in the treatment of single level lumbar spondylolisthesis. Methods: Retrospective analysis was made on 32 cases ... Objectives: To investigate the effect of lumbar interbody fusion via the oblique lateral approach (OLIF) in the treatment of single level lumbar spondylolisthesis. Methods: Retrospective analysis was made on 32 cases of single level lumbar spondylolisthesis treated by lumbar interbody fusion via the oblique lateral approach from July 2020 to July 2021. 14 males and 18 females;the age was (66.5 ± 11.5) years (55 - 82 years). 1) The operation time, intraoperative blood loss and complications were recorded;2) the scores of visual analog scale. VAS and Oswestry disability index (ODI) of low back pain and lower limb pain were collected before operation and at the last follow-up;by observing the imaging data, the height of the intervertebral space, the anterior convex angle of the intervertebral space, the anterior convex angle of the lumbar spine, the sagittal diameter of the dural sac and the spondylolisthesis were measured. Results: All patients successfully completed the operation, the average operation time was (103.9 ± 21.1) min, the average intraoperative bleeding volume was (72.3 ± 16.4) ml. There was no vascular injury during the operation, no infection occurred in all surgical incisions, and Class I/A healing was achieved. The VAS scores of low back pain and leg pain before operation and at the last follow-up were lower than those before operation, and the difference was statistically significant (P < 0.05);the ODI at the last follow-up was lower than that before operation, and the difference was statistically significant (P < 0.05). At the last follow-up, the height of intervertebral space, the height of intervertebral foramen and the sagittal diameter of dural sac were greater than those before operation, with statistically significant differences (P < 0.05);the spondylolisthesis rate at the last follow-up was lower than that before operation, with a statistically significant difference (P < 0.05). Left thigh surface numbness occurred in 2 cases (6.3%) and disappeared after 1 week;Hip flexion weakness occurred in 1 case (0.03%), which recovered after 12 days;there were no complications such as retroperitoneal hematoma, ureteral injury, retrograde ejaculation, intestinal and lumbar plexus injury. Conclusion: The early clinical effect of OLIF in the treatment of single level lumbar spondylolisthesis is significant. This surgical method is minimally invasive, safe and effective, which can significantly reduce the amount of intraoperative bleeding and reduce the risk of postoperative complications. Its main working principle is to make the annulus fibrosus, posterior longitudinal ligament and ligamentum flavum shrink and recover the height of the intervertebral space through decompression, loosening and stretching of the intervertebral space, so as to achieve the reduction of the slipped vertebral body, increase the height of the intervertebral foramen Enlarge the spinal canal volume and eliminate dynamic compression to play an indirect decompression role, improve the symptoms of low back and leg pain, and reconstruct the stability of the spine through interbody fusion. 展开更多
关键词 Oblique Lateral Approach Lumbar Interbody Fusion Single Segment Lumbar Spondylolisthesis
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Prototype of a deep-sea in-situ neutron activation spectrometer for polymetallic nodule and crust exploration
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作者 Xiao-Hu Wang ping cao +2 位作者 Bin Zhou Yuan-Da Wang Yu Zhu 《Nuclear Science and Techniques》 2025年第9期116-128,共13页
In-situ exploration of deep-sea seabed resources is a valuable research direction.Neutron activation-based in-situ exploration methods for seabed polymetallic nodules or crust resources are theoretically feasible beca... In-situ exploration of deep-sea seabed resources is a valuable research direction.Neutron activation-based in-situ exploration methods for seabed polymetallic nodules or crust resources are theoretically feasible because of the high content and high neutron capture cross-section of manganese in these nodules or crusts.However,to date,only a few relevant studies have been conducted.In this study,a prototype deep-sea in-situ neutron activation spectrometer(DINAS)was designed for resource exploration.Through an analysis of the principles of the spectrometer combined with Monte Carlo simulations of the physical principles and finite element simulations of deep-sea pressure,the structure and fundamental components of the spectrometer were determined.The inner core of the spectrometer comprised three components:a compact neutron generator for neutron production,gamma-ray detectors,and an electronics system.The gamma-ray detector array of the spectrometer consisted of LaBr_(3)and Bi_(4)Ge_(3)O_(12)scintillation crystals coupled with silicon photomultiplier arrays.The electronics system was divided into two modules to implement the SiPM readout and digital signal analysis along the modular design lines.The experimental activation of neutron beamlines at the China Spallation Neutron Source demonstrated the capability of the spectrometer detectors to detect activated gamma-rays and showed that the spectrometer achieved an energy resolution of 2.8%at 847 keV for the LaBr_(3)detector and 6.7%at 2.113 MeV for the BGO detector.The laboratory model experiment tested the functionality of the spectrometer prototype,whereas the Geant4 simulation verified the reliability of the Monte Carlo method.The method and prototype proposed in this study proved feasible for the in-situ detection of polymetallic nodules or crusts in deep-sea environments. 展开更多
关键词 Gamma-ray detector Neutron activation Readout electronics
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回阳固元方对人乳头瘤病毒感染细胞凋亡的影响研究
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作者 曹萍 朱伟 杨同华 《中国现代医学杂志》 CAS 2019年第15期21-25,共5页
目的探讨回阳固元方对人乳头瘤病毒感染细胞凋亡的影响。方法用不同浓度回阳固元方,经Transwell(转换池)吸收后,与尖锐湿疣患者皮损中提取的角质形成细胞-单细胞悬液作用,通过流式细胞仪测定其细胞周期及细胞凋亡。结果固定中药浓度20μ... 目的探讨回阳固元方对人乳头瘤病毒感染细胞凋亡的影响。方法用不同浓度回阳固元方,经Transwell(转换池)吸收后,与尖锐湿疣患者皮损中提取的角质形成细胞-单细胞悬液作用,通过流式细胞仪测定其细胞周期及细胞凋亡。结果固定中药浓度20μg/ml,随着时间的变化,G1期细胞数量减少,G2期细胞数量逐渐增多,S期细胞数量较正常组减少,角质形成细胞的凋亡率也逐渐增加;固定时间48 h,随着中药浓度的增加,G1期细胞数量降低,G2期细胞数量极少,S期细胞较正常组减少,角质形成细胞的凋亡率呈逐渐增加的趋势(P<0.05)。结论回阳固元方可诱导人乳头瘤病毒感染细胞的凋亡。 展开更多
关键词 尖锐湿疣 角质形成细胞 细胞培养 细胞周期 细胞凋亡
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Back-n white neutron source at CSNS and its applications 被引量:23
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作者 Jing-Yu Tang Qi An +73 位作者 Jiang-Bo Bai Jie Bao Yu Bao ping cao Hao-Lei Chen Qi-ping Chen Yong-Hao Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Xi-Ru Huang Hao-Yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang Bo Li Chao Li Jia-Wen Li Qiang Li Xiao Li Yang Li Jie Liu Rong Liu Shu-Bin Liu Xing-Yan Liu Ze Long Guang-Yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Xin-Yi Tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Li-Kun Xie Xiao-Yun Yang Yi-Wei Yang Han Yi Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Lu-ping Zhou Zhi-Hao Zhou Ke-Jun Zhu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2021年第1期95-104,共10页
Back-streaming neutrons from the spallation target of the China Spallation Neutron Source(CSNS)that emit through the incoming proton channel were exploited to build a white neutron beam facility(the so-called Back-n w... Back-streaming neutrons from the spallation target of the China Spallation Neutron Source(CSNS)that emit through the incoming proton channel were exploited to build a white neutron beam facility(the so-called Back-n white neutron source),which was completed in March 2018.The Back-n neutron beam is very intense,at approximately 29107 n/cm2/s at 55 m from the target,and has a nominal proton beam with a power of 100 kW in the CSNS-I phase and a kinetic energy of 1.6 GeV and a thick tungsten target in multiple slices with modest moderation from the cooling water through the slices.In addition,the excellent energy spectrum spanning from 0.5 eV to 200 MeV,and a good time resolution related tothe time-of-flight measurements make it a typical white neutron source for nuclear data measurements;its overall performance is among that of the best white neutron sources in the world.Equipped with advanced spectrometers,detectors,and application utilities,the Back-n facility can serve wide applications,with a focus on neutron-induced cross-sectional measurements.This article presents an overview of the neutron beam characteristics,the experimental setups,and the ongoing applications at Backn. 展开更多
关键词 White neutron source Nuclear data measurements Experimental setups Neutron applications
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Progressive failure analysis of slope with strain-softening behaviour based on strength reduction method 被引量:11
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作者 Ke ZHANG ping cao Rui BAO 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2013年第2期101-109,共9页
Based on the strength reduction method and strain-softening model,a method for progressive failure analysis of strain-softening slopes was presented in this paper.The mutation is more pronounced in strain-softening an... Based on the strength reduction method and strain-softening model,a method for progressive failure analysis of strain-softening slopes was presented in this paper.The mutation is more pronounced in strain-softening analysis,and the mutation of displacement at slope crest was taken as critical failure criterion.An engineering example was provided to demonstrate the validity of the present method.This method was applied to a cut slope in an industry site.The results are as follows:(1) The factor of safety and the critical slip surface obtained by the present method are between those by peak and residual strength.The analysis with peak strength would lead to non-conservative results,but that with residual strength tends to be overly conservative.(2) The thickness of the shear zone considering strain-softening behaviour is narrower than that with non-softening analysis.(3) The failure of slope is the process of the initiation,propagation and connection of potential failure surface.The strength parameters are mobilized to a non-uniform degree while progressive failure occurs in the slope.(4) The factor of safety increases with the increase of residual shear strain threshold and elastic modulus.The failure mode of slope changes from shallow slip to deep slip.Poisson's ratio and dilation angle have little effect on the results. 展开更多
关键词 Shear strength reduction STRAIN-SOFTENING Peak strength Residual strength Progressive failure analysis
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Measurement of the neutron total cross section of carbon at the Back-n white neutron beam of CSNS 被引量:7
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作者 Xing-Yan Liu Yi-Wei Yang +79 位作者 Rong Liu Jie Wen Zhong-Wei Wen Zi-Jie Han Zhi-Zhou Ren Qi An Huai-Yong Bai Jie Bao ping cao Qi-ping Chen Yong-Hao Chen Pin-Jing Cheng Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Min-Hao Gu Feng-Qin Guo Chang-Cai Han Guo-Zhu He Yong-Cheng He Yue-Feng He Han-Xiong Huang Wei-Ling Huang Xi-Ru Huang Xiao-Lu Ji Xu-Yang Ji Hao-Yu Jiang Wei Jiang Han-Tao Jing Ling Kang Ming-Tao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Shu-Bin Liu Guang-Yuan Luan Ying-Lin Ma Chang-Jun Ning Bin-Bin Qi Jie Ren Xi-Chao Ruan Zhao-Hui Song Hong Sun Xiao-Yang Sun Zhi-Jia Sun Zhi-Xin Tan Hong-Qing Tang Jing-Yu Tang Peng-Cheng Wang Qi Wang Tao-Feng Wang Yan-Feng Wang Zhao-Hui Wang Zheng Wang Qing-Biao Wu Xiao-Guang Wu Xuan Wu Li-Kun Xie Han Yi Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Jing Zhang Lin-Hao Zhang Li-Ying Zhang Qing-Min Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Ying-Tan Zhao Liang Zhou Zu-Ying Zhou Dan-Yang Zhu Ke-Jun Zhu Peng Zhu 《Nuclear Science and Techniques》 SCIE CAS CSCD 2019年第9期73-82,共10页
To verify the performance of the neutron total cross-sectional spectrometer, the neutron total cross section of carbon is initially measured in the energy range of 1 eV to 20 MeV using the time-of-flight method. The m... To verify the performance of the neutron total cross-sectional spectrometer, the neutron total cross section of carbon is initially measured in the energy range of 1 eV to 20 MeV using the time-of-flight method. The measurement is performed at the Back-n white neutron source with a 76-m time-of-flight path using the China Spallation Neutron Source. A multilayer fast fission chamber with 235U and 238U is employed as the neutron detector. The diameter and thickness of the natural graphite sample are 70 mm and 40 mm, respectively. Signal waveforms are collected using a data acquisition system. Off-line data processing was used to obtain the neutron time-of-flight spectra and transmissions. The uncertainty of the counting statistics is generally approximately 3% for each bin in the energy range of 1–20 MeV. It is determined that the results for the neutron total cross section of carbon obtained using ^235U cells are in good agreement with the results obtained using 238U cells within limits of statistical uncertainty. Moreover, the measured total cross sections show good agreement with the broadening evaluated data. 展开更多
关键词 CSNS Back-n WHITE NEUTRON source NTOX NEUTRON total cross section CARBON Multilayer fast FISSION chamber
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Strength and failure characteristics of brittle jointed rock-like specimens under uniaxial compression:Digital speckle technology and a particle mechanics approach 被引量:14
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作者 Rihong cao Hang Lin ping cao 《International Journal of Mining Science and Technology》 EI CSCD 2018年第4期662-670,共9页
The strength and failure characteristics of most natural rock mass are influenced by discontinues such as fissures, joints, and weak surfaces. In the present study, the strength and failure behavior of ubiquitous- joi... The strength and failure characteristics of most natural rock mass are influenced by discontinues such as fissures, joints, and weak surfaces. In the present study, the strength and failure behavior of ubiquitous- joint rock-l!ke specimens under uniaxial loading have been investigated by DIC (digital image correlation) and discrete element numerical method (PFC2D). The results are obtained. Firstly, the UCSJ of spec- imens with γ= 15° or 30° shows similar tendency while α goes from 0° to 75°. With γ= 45° or 60°, the UCSJ of specimens increases when α goes from 0° to 30° and decreases after α goes beyond 30°. With γ=75°, the peak UCSJ value is reached when α=0°. The UCSJ value shows an increasing trend when α goes from 60° to 75°. Secondly, the ubiquitous-joint specimens present different failure modes for various levels of α and γ(β-α). Based on the experimental results, the failure mode of ubiquitous-joint specimens can be classified into three categories: stepped path failure, failure through parallel plane, and failure through cross plane. 展开更多
关键词 Ubiquitous-joint Digital speckle correlation technique PFC2D STRENGTH Failure mode
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Gastrointestinal tract distribution of Salmonella enteritidis in orally in fected mice with a species-specific fluorescent quantitative polymerase chain reaction 被引量:12
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作者 Shu-Xuan Deng An-Chun Cheng +1 位作者 Ming-Shu Wang ping cao 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第48期6568-6574,共7页
AIM: To identify and understand the regular distribution pattern and primary penetration site for Salmonella enteritidis (S. enteritidis) in the gastrointestinal tract. METHODS: Based on the species-specific DNA seque... AIM: To identify and understand the regular distribution pattern and primary penetration site for Salmonella enteritidis (S. enteritidis) in the gastrointestinal tract. METHODS: Based on the species-specific DNA sequence of S. enteritidis from GenBank, a species-specific real- time, fluorescence-based quantitative polymerase chain reaction (FQ-PCR) was developed for the detection of S. enteritidis. We used this assay to detect genomic DNA of S. enteritidis in the gastrointestinal tract, including duodenum, jejunum, ileum, cecum, colon, rectum, esophagus and stomach, from mice after oral infection. RESULTS: S. enteritidis was consistently detected in all segments of the gastrointestinal tract. The jejunum and ileum were positive at 8 h post inoculation, and the final organ to show a positive result was the stomach at 18 h post inoculation. The copy number of S. enteritidis DNA in each tissue reached a peak at 24-36 h post inoculation, with the jejunum, ileum and cecum containing high concentrations of S. enteritidis, whereas the duodenum, colon, rectum, stomach and esophagus had low concentrations. S. enteritidis began to decrease and vanished at 2 d post inoculation, but it was still present up to 5 d post inoculation in the jejunum, ileum andcecum, without causing apparent symptoms. By 5 d post inoculation, the cecum had significantly higher numbers of S. enteritidis than any of the other areas (P < 0.01), and this appeared to reflect its function as a repository for S. enteritidis. CONCLUSION: The results provided significant data for clarifying the pathogenic mechanism of S. enteritidis in the gastrointestinal tract, and showed that the jejunum, ileum and cecum are the primary sites of invasion in normal mice after oral infection. This study will help to further understanding of the mechanisms of action of S. enteritidis. 展开更多
关键词 Fluorescence-based quantitative polymerase chain reaction Gastrointestinal tract Salmonella enteritidis
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Three-dimensional upper bound limit analysis of underground cavities using nonlinear Baker failure criterion 被引量:8
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作者 Zhi-zhen LIU ping cao +2 位作者 Hang LIN Jing-jing MENG Yi-xian WANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2020年第7期1916-1927,共12页
A generalized nonlinear Baker failure criterion is employed with the upper bound limit analysis to study the surrounding rock stability of underground cavities. A three-dimensional(3D) failure mode is established by e... A generalized nonlinear Baker failure criterion is employed with the upper bound limit analysis to study the surrounding rock stability of underground cavities. A three-dimensional(3D) failure mode is established by extending the two-dimensional(2D) failure mode, which offers an upper bound expression of the surrounding rock pressure. This method is validated with a series of examples before the influence of four parameters of scale parameter, curvature parameter, shift parameter and lateral pressure coefficient, on the surrounding rock pressure is analyzed. According to these results, failure ranges of the underground cavities are determined. The following conclusions are reached:(1) the proposed approach is more accurate to predict surrounding rock pressure than the Mohr-Coulomb failure criterion;(2) the surrounding rock with large scale parameter, curvature parameter, shift parameter, and lateral pressure coefficient can lead to a more stable underground cavity;(3) the failure range in 3D mode can be predicted according to the upper bound solutions. 展开更多
关键词 Baker failure criterion underground cavity surrounding rock pressure 3D failure mode upper bound limit analysis
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Application of an indirect immunofluorescent staining method for detection of Salmonella enteritidis in paraffin slices and antigen location in infected duck tissues 被引量:7
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作者 Bin Yan An-Chun Cheng +5 位作者 Ming-Shu Wang Shu-Xuan Deng Zhen-Hua Zhang Nian-Chun Yin ping cao Sheng-Yan cao 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第5期776-781,共6页
AIM: To detect Salmonella enteritidis (S. enteritidis) in paraffin slices and antigen location in infected duck tissues. METHODS: The rabbits were immunized with purified bacillus to obtain S. enteritidis-specific... AIM: To detect Salmonella enteritidis (S. enteritidis) in paraffin slices and antigen location in infected duck tissues. METHODS: The rabbits were immunized with purified bacillus to obtain S. enteritidis-specific antibody, which were then extracted by the caprylic-ammonium sulphate method, purified through High-Q columns. An indirect immuno-fluorescent staining method (IFA) was established to detect the S. enteritidis antigen in paraffin slices. Detected S. enteritidis in each organ tissue of ducklings experimentally infected with S. enteritidis. RESULTS: The gland of Garder, heart, kidney, spleen, liver, brain, ileum, jejunum, bursa of Fabricius from S. enteritidis experimentally infected ducklings were positive or strongly positive, and the S. enteritidis antigen mainly distributed in the infected cell cytoplasm.CONCLUSION: IFA is an intuitionist, sensitive and specific method in detecting S. enteritidis antigen in paraffin wax slices, and it is a good method in diagnosis and antigen location of S. enteritidis. We also conclude that the gland of Garder, heart, kidney, spleen, liver, ileum, jejunum are target organs in S. enteritidis infections of duck, and S. enteritidis is an intracellular parasitic bacterium. 展开更多
关键词 Indirect immuno-fluorescent antibody staining Salrnonella enteritidis Paraffin tissues DETECTION Localization of antigens
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Quantitative studies of the regular distribution pattern for Salmonella enteritidis in the internal organs of mice after oral challenge by a specific real-time polymerase chain reaction 被引量:7
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作者 Shu-Xuan Deng An-Chun Cheng +5 位作者 Ming-Shu Wang ping cao Bin Yan Nian-Chun Yin Sheng-Yan cao Zhen-Hua Zhang 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第5期782-789,共8页
AIM: To identify and understand the regular distribution pattern for Salmonella enteritidis (S. enteritidis) in the internal organs of mice after an oral challenge over a 3 wk period. METHODS: Assays based on the ... AIM: To identify and understand the regular distribution pattern for Salmonella enteritidis (S. enteritidis) in the internal organs of mice after an oral challenge over a 3 wk period. METHODS: Assays based on the serovar-specific DNA sequence of S. enteritidis from GenBank, and a serovar-specific real-time, fluorescence-based quantitative polymerase chain reaction (FQ-PCR) were developed for the detection of S. enteritidis. We used this assay to detect genomic DNA of S. enteritidis in the blood and the internal organs, including heart, liver, spleen, kidney, pancreas, and gallbladder, from mice after oral challenge at different time points respectively.RESULTS: The results showed that the spleen was positive at 12 h post inoculation (PI), and the blood was at 14 h PI. The organism was detected in the liver and heart at 16 h PI, the pancreas was positive at 20 h PI, and the final organs to show positive results were the kidney and gallbladder at 22 h PI. The copy number of S. enteritidis DNA in each tissue reached a peak at 24-36 h PI, with the liver and spleen containing high concentrations of S. enteritidis, whereas the blood, heart, kidney, pancreas, and gallbladder had low concentrations. S. enteritidis populations began to decrease and were not detectable at 3 d PI, but were still present up to 12 d PI in the gallbladder, 2 wk for the liver, and 3 wk for the spleen without causing apparent symptoms.CONCLUSION: The results provided significant data for understanding the life cycle of S. enteritidis in the internal organs, and showed that the liver and spleen may be the primary sites for setting itself up as a commensa over a long time after oral challenge. Interestingly, it may be the first time reported that the gallbladder is a site of carriage for S. enteritidis over a 12 d period. This study will help to understand the mechanisms of action of S. enteriCdis infection in vivo. 展开更多
关键词 Fluorescence-based quantitative polymerase chain reaction Internal organs Salmonella enteritidis Regular distribution pattern
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Measurement of the ^(232)Th(n,f)cross section in the 1-200 MeV range at the CSNS Back-n 被引量:5
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作者 Zhi-Zhou Ren Yi-Wei Yang +77 位作者 Yong-Hao Chen Rong Liu Bang-Jiao Ye Jie Wen Hai-Rui Guo Zi-Jie Han Qi-ping Chen Zhong-Wei Wen Wei-Li Sun Han Yi Xing-Yan Liu Tao Ye Jiang-Bo Bai Qi An Jie Bao Yu Bao ping cao Hao-Lei Chen Zhen Chen Zeng-Qi Cui Rui-Rui Fan Chang-Qing Feng Ke-Qing Gao Xiao-Long Gao Min-Hao Gu Chang-Cai Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Xi-Ru Huang Hao-Yu Jiang Wei Jiang Zhi-Jie Jiang Han-Tao Jing Ling Kang Bo Li Chao Li Jia-Wen Li Qiang Li Xiao Li Yang Li Jie Liu Shu-Bin Liu Ze Long Guang-Yuan Luan Chang-Jun Ning Meng-Chen Niu Bin-Bin Qi Jie Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Jia Sun Zhi-Xin Tan Jing-Yu Tang Xin-Yi Tang Bin-Bin Tian Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Xiao-Guang Wu Xuan Wu Li-Kun Xie Xiao-Yun Yang Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Zhi-Yong Zhang Lu-ping Zhou Zhi-Hao Zhou Ke-Jun Zhu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2023年第8期142-153,共12页
The ^(232)Th(n,f)cross section is very important in basic nuclear physics and applications based on the Th/U fuel cycle.Using the time-of-flight method and a multi-cell fast-fission ionization chamber,a novel measurem... The ^(232)Th(n,f)cross section is very important in basic nuclear physics and applications based on the Th/U fuel cycle.Using the time-of-flight method and a multi-cell fast-fission ionization chamber,a novel measurement of the^(232)Th(n,f)cross sec-tion relative to^(235)U in the 1–200 MeV range was performed at the China Spallation Neutron Source Back-n white neutron source(Back-n).The fission event-neutron energy spectra of^(232)Th and^(235)U fission cells were measured in the single-bunch mode.Corrected 232Th/235U fission cross-sectional ratios were obtained,and the measurement uncertainties were 2.5–3.7%for energies in the 2–20 MeV range and 3.6–6.2%for energies in the 20–200 MeV range.The^(232)Th(n,f)cross section was obtained by introducing the standard cross section of^(235)U(n,f).The results were compared with those of previous theoreti-cal calculations,measurements,and evaluations.The measured 232Th fission cross section agreed with the main evaluation results in terms of the experimental uncertainty,and 232Th fission resonances were observed in the 1–3 MeV range.The present results provide^(232)Th(n,f)cross-sectional data for the evaluation and design of Th/U cycle nuclear systems. 展开更多
关键词 232Th(n f)cross section Fast-fission ionization chamber Back-n white neutron source
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FPGA-based position reconstruction method for neutron beam flux spatial distribution measurement in BNCT 被引量:4
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作者 Wei Jiang ping cao +5 位作者 Yi-Ming Wu Xian-Ke Liu Zhu-Jun Fang Zhi-Yong Zhang Bin Shi Jun Chen 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第3期96-108,共13页
A new measurement method for the spatial distribution of neutron beam flux in boron neutron capture therapy(BNCT)is being developed based on the two-dimensional Micromegas detector.To address the issue of long process... A new measurement method for the spatial distribution of neutron beam flux in boron neutron capture therapy(BNCT)is being developed based on the two-dimensional Micromegas detector.To address the issue of long processing times in traditional offline position reconstruction methods,this paper proposes a field programmable gate array based online position reconstruction method utilizing the micro-time projection chamber principle.This method encapsulates key technical aspects:a self-adaptive serial link technique built upon the dynamical adjustment of the delay chain length,fast sorting,a coordinate-matching technique based on the mapping between signal timestamps and random access memory(RAM)addresses,and a precise start point-merging technique utilizing a circular combined RAM.The performance test of the selfadaptive serial link shows that the bit error rate of the link is better than 10-12 at a confidence level of 99%,ensuring reliable data transmission.The experiment utilizing the readout electronics and Micromegas detector shows a spatial resolution of approximately 1.4 mm,surpassing the current method’s resolution level of 5 mm.The beam experiment confirms that the readout electronics system can obtain the flux spatial distribution of neutron beams online,thus validating the feasibility of the position reconstruction method.The online position reconstruction method avoids traditional methods,such as bubble sorting and traversal searching,simplifies the design of the logic firmware,and reduces the time complexity from O(n2)to O(n).This study contributes to the advancement in measuring neutron beam flux for BNCT. 展开更多
关键词 Position reconstruction FPGA Readout electronics Neutron flux spatial distribution
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Deformation and damage properties of rock-like materials subjected to multi-level loading-unloading cycles 被引量:2
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作者 Zhizhen Liu ping cao +2 位作者 Qingxiong Zhao Rihong cao Fei Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2023年第7期1768-1776,共9页
In the process of engineering construction such as tunnels and slopes,rock mass is frequently subjected to multiple levels of loading and unloading,while previous research ignores the impact of unloading rate on the s... In the process of engineering construction such as tunnels and slopes,rock mass is frequently subjected to multiple levels of loading and unloading,while previous research ignores the impact of unloading rate on the stability of rock mass.A number of uniaxial multi-level cyclic loading-unloading experiments were conducted to better understand the effect of unloading rate on the deformation behavior,energy evolution,and damage properties of rock-like material.The experimental results demonstrated that the unloading rate and relative cyclic number clearly influence the deformation behavior and energy evo-lution of rock-like samples.In particular,as the relative cyclic number rises,the total strain and reversible strain both increase linearly,while the total energy density,elastic energy density,and dissipated energy density all rise nonlinearly.In contrast,the irreversible strain first decreases quickly,then stabilizes,and finally rises slowly.As the unloading rate increases,the total strain and reversible strain both increase,while the irreversible strain decreases.The dissipated energy damage was examined in light of the aforementioned experimental findings.The accuracy of the proposed damage model,which takes into account the impact of the unloading rate and relative cyclic number,is then confirmed by examining the consistency between the model predicted and the experimental results.The proposed damage model will make it easier to foresee how the multi-level loading-unloading cycles will affect the rock-like materials. 展开更多
关键词 Incremental cyclic loading-unloading Unloading rate Strain characteristics Energy evolution Damage model
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Relationship between loading angle and displacing angle in steel bolt shearing 被引量:2
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作者 Yu CHEN ping cao +1 位作者 Ke-ping ZHOU Yun TENG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2017年第4期876-882,共7页
When subjected to shear loading condition,a steel rock bolt will become bent in the field close to the loading point in situ.The bolt is deformed as the joint displacement increases,which can mobilize a normal load an... When subjected to shear loading condition,a steel rock bolt will become bent in the field close to the loading point in situ.The bolt is deformed as the joint displacement increases,which can mobilize a normal load and a shear load on the bolt accordingly.In this work,the relationship analysis between the displacing angle and loading angle is carried out.By considering elastic andplastic states of rock bolt during shearing,the rotation of bolt extremity can be calculated analytically.Thus,the loading angle isobtained from displacing angle.The verification of analytical results and laboratory results from reference research implies that theanalytical method is correct and working.In terms of in-situ condition,the direction of the load acting on steel bolt can be predictedwell according to the direction of the deformed rock bolt with respect to original bolt axis. 展开更多
关键词 steel rock bolt SHEAR displacing angle loading angle
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Effects of ramipril on ventricular arrhythmia after myocardial infarction in rabbits 被引量:3
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作者 Ya Zhong ping cao +1 位作者 Chuan-feng Tong Xia Li 《World Journal of Emergency Medicine》 CAS 2014年第2期135-138,共4页
BACKGROUND: Ventricular arrhythmia (VA) is one of the most common complications of myocardial infarction (MI), and ventricular tachycardia and fibrillation are the main causes for sudden cardiac death. This study... BACKGROUND: Ventricular arrhythmia (VA) is one of the most common complications of myocardial infarction (MI), and ventricular tachycardia and fibrillation are the main causes for sudden cardiac death. This study aimed to explore the effect of ramipril on the occurrence of VA and its mechanism after MI in rabbits. METHODS: Twenty-four New Zealand rabbits purchased from the Wuhan Laboratory Animal Research Center were divided into three groups: sham-operated (SHAM) group (n=8), MI group (n=8) and MI with ramipril (RAM) group (n=8). Rabbits in the SHAM group received a median sternotomy without ligation of the left ventricular coronary artery. Rabbits in the MI and RAM groups received a median sternotomy followed by ligation of the left coronary artery. The successful anterior MI was confirmed by elevation of the ST segment with more than 0.2 mV in lead II and II1. After MI, rabbits in the RAM group were fed with intragastric ramipril (1 mg/kg per day ) for 12 weeks. Before and 12 weeks after MI in the three groups, ventricular tachycardia or fibrillation (VT/VF) episodes and MAP in cadiocytes of the epicardium, mid-myocardium and endocardium were recorded by a multichannel physiograph. Student's t test and ANOVA were used for statistical analysis. RESULTS: VT/VF episodes were decreased more markedly in the RAM group than in the MI group after 12 weeks (2.6±0.8 vs. 12.±+2.9, P〈0.05). Twelve weeks after MI, the duration of repolarization for 90% (APD90) of three-tier ventricular myocytes in the MI group was longer than that before MI (258.2±21.1 vs. 230.1±23.2,278.0±23.8 vs. 245.8±25.4,242.6±22.7 vs. 227.0±21.7, P〈0.05). However, the APD90 was not significantly different at 12 weeks before and after MI in the RAM group (P〉0.05). Moreover, the transmural dispersion of repolarization (TDR) was increased more markedly 12 weeks after MI in the MI group than in the SHAM and RAM groups (36.2±10.2 vs. 18.7±6.2, 24.9±8.7, P〈0.05). But the TDR was not significantly different between the RAM and SHAM groups (18.7±6.2 vs. 24.9±8.7, P〉0.05). CONCLUSION: Ramipril may reduce the incidence of malignant ventricular arrhythmia via mprovement of transmembrance repolarization heterogeneity after MI. 展开更多
关键词 Myocardial infarction Ventricular arrhythmia Monophasic action potentia duration Transmural dispersion of repolarization RAMIPRIL RABBITS
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Investigation on ignition characteristics of charring conductive polymers stimulated by electric energy 被引量:1
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作者 Zhiyuan ZHANG Hanyu DENG +2 位作者 Wenhe LIAO Yantao PU ping cao 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2024年第10期68-82,共15页
The arc ignition based on charring conductive polymers has advantages of simple structure,low ignition power consumption and restart capacity,which bringing it broadly application prospect in hybrid propulsion system ... The arc ignition based on charring conductive polymers has advantages of simple structure,low ignition power consumption and restart capacity,which bringing it broadly application prospect in hybrid propulsion system of micro/nano satellite.In order to optimize the performance of arc ignition system,it is essential to have a deeper understanding of the ignition processes and ignition characteristics of charring conductive polymers.In this paper,the thermal decomposition,electrical conductivity and thermal conductivity characteristics of charring conductive polymers with different conductive additives and matrix materials were comprehensively evaluated.An experimental investigation was conducted to determine the ignition behaviors and characteristics of different charring conductive polymers in a visual ignition combustor.The experiment result showed that the ignition delay and external energy required for ignition are negatively correlated with voltage and initial temperature of the ignition grain,but positively correlated with oxidizer flow velocity.Compared with charring conductive polymers containing multi-walled carbon nanotube,the ignition delay of charring conductive polymers with carbon black is significantly higher and the pyrolysis time is relatively longer.However,the ignition and initial flame propagation of charring conductive polymers with carbon black is more violent and more inclined to carbon particle ignition.Finally,the restart characteristic of different charring conductive polymers was studied.The ignition delay and external energy required for ignition of different charring conductive polymers all reduced with the increasing of the number of ignitions.However,the ignition characteristics would not change a lot after repeated ignition. 展开更多
关键词 Micro/nano satellite hybrid rocket motors Arc ignition Charring conductive polymer Ignition process Ignition characteristic Restart characteristic
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Reliability analysis of large-diameter high-grade-steel natural gas pipelines under fault action 被引量:1
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作者 Xiao-Ting Gu Xue-Rui Zang +4 位作者 Zhen-Yong Zhang Peng Yang Wen-Zhen Miao ping cao Bin Zhao 《Petroleum Science》 SCIE CAS CSCD 2022年第5期2387-2398,共12页
There are a lot of researches on qualitative aseismatic measures for buried gas pipeline crossing movable faults.But a few of them are quantitative,especially in the size and shape of the trench.The paper first establ... There are a lot of researches on qualitative aseismatic measures for buried gas pipeline crossing movable faults.But a few of them are quantitative,especially in the size and shape of the trench.The paper first established the finite element model of the strain of buried pipeline crossing a fault which effected by the size and shape of the trench.And it obtained new soil spring stiffness which considered different buried depth,bottom width of trench,trench slope and elastic modulus of soil.The mechanical analysis model of pipeline is established,and the limit state equation of pipeline is fitted.The reliability and sensitivity of the natural gas pipeline under fault action are analysed by a Monte Carlo method,and the error and accuracy are verified.When the pipeline is under tension,the sensitivity from large to small is buried depth,sand friction angle,pipe diameter,pipeline displacement,trench bottom width,trench depth,clay cohesion,trench slope and clay friction angle;when the pipeline is under pressure,the trench depth and clay cohesion have great influence.The findings of this study provide a reference for pipeline design and safety evaluation under fault action. 展开更多
关键词 Trench parameters Natural gas pipeline FAULT Soil-pipeline interaction Soil spring stiffness
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Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n 被引量:1
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作者 Sheng-Da Tang Yong-Hao Chen +72 位作者 Jing-Yu Tang Rui-Rui Fan Qiang Li Gong Li Dong Liu Zheng-Yao Jin Xing-Zhu Cui Tian-Xiang Chen Yi-Wei Yang Rong Liu Han Yi Yang Li Zhen Yang Qi An Hao-Fan Bai Jiang-Bo Bai Jie Bao ping cao Qi-ping Chen Zhen Chen Zeng-Qi Cui An-Chuan Fan Chang-Qing Feng Fan-Zhen Feng Ke-Qing Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Wei-Hua Jia Hao-yu Jiang Wei Jiang Zhi-jie Jiang Ling Kang Bo Li Chao Li Jia-Wen Li Xiao Li Jie Liu Shu-Bin Liu Guang-Yuan Luan Chang-Jun Ning Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Xin Tan Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Li-Kun Xie Yong-Ji Yu Guo-Hui Zhang Lin-Hao Zhang Mo-Han Zhang Qi-Wei Zhang Xian-Peng Zhang Yu-Liang Zhang Yue Zhang Zhi-Yong Zhang Mao-Yuan Zhao Lu-ping Zhou Zhi-Hao Zhou Ke-Jun Zhu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第1期178-187,共10页
Nondestructive and noninvasive neutron assays are essential applications of neutron techniques.Neutron resonance transmission analysis(NRTA)is a powerful nondestructive method for investigating the elemental compositi... Nondestructive and noninvasive neutron assays are essential applications of neutron techniques.Neutron resonance transmission analysis(NRTA)is a powerful nondestructive method for investigating the elemental composition of an object.The back-streaming neutron line(Back-n)is a newly built time-of-flight facility at the China Spallation Neutron Source(CSNS)that provides neutrons in the eV to 300 MeV range.A feasibility study of the NRTA method for nuclide identification was conducted at the CSNS Back-n via two test experiments.The results demonstrate that it is feasible to identify different elements and isotopes in samples using the NRTA method at Back-n.This study reveals its potential future applications. 展开更多
关键词 CSNS White neutron beam NRTA Nuclide identification Nondestructive method
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