<strong>Background:</strong><span style="font-family:Verdana;"> The SARS-CoV-2 and associated corona virus disease COVID-19</span><span style="font-family:Verdana;"> h...<strong>Background:</strong><span style="font-family:Verdana;"> The SARS-CoV-2 and associated corona virus disease COVID-19</span><span style="font-family:Verdana;"> ha</span><span style="font-family:Verdana;">ve</span><span style="font-family:Verdana;"> been declared a pandemic having a poor prognosis among individuals with debilitating conditions and those who are immune</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">compromised. Current evidence is however limited on maternal and fetal transmission and pregnancy outcomes. We aimed to describe the pattern of SARS-CoV-2 infection and outcomes in a group of pregnant women followed</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">up at a tertiary care unit in Cameroon. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">This was an observational study conducted over a period of 3 months (April 1</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">to June 30, 2020) at the Yaounde Central Hospital. All pregnant women who were tested positive for SARS-CoV-2 and who provided a signed written informed consent were included in the study. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">Out of 83 pregnant women who presented with symptoms suspicious of COVID-19, 25 were tested positive. The median age of these women was 31 (27 </span></span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> 35)</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">years. A total of 76% consulted within 6 days of onset of symptoms and 68% had a gestational age greater than 28 weeks. The most comm</span><span style="font-family:Verdana;">on </span><span style="font-family:Verdana;">presenting complaint was fever (88%). All 25 pregnant women who </span></span><span style="font-family:Verdana;">were </span><span style="font-family:Verdana;">tested posit</span><span style="font-family:Verdana;">i</span><span style="font-family:Verdana;">ve for COVID-19 were followed up with 9/25 deliveries registered. There were two intra-uterine f</span><span style="font-family:Verdana;">e</span><span style="font-family:Verdana;">tal death</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> and seven live births. All the live birth babies </span><span style="font-family:Verdana;">were </span><span style="font-family:""><span style="font-family:Verdana;">tested negative on Real Time-Polymerase Chain Reaction (RT-PCR) testing which was performed after birth. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">Deliverance of live and SARS-CoV-2 negative babies from COVID-19 pregnant women is possible.</span></span>展开更多
Background: Infertility is a global problem, but the highest prevalence is in low resource countries, particularly in sub-Saharan Africa where tubal damage following pelvic infection is the commonest cause. Objectives...Background: Infertility is a global problem, but the highest prevalence is in low resource countries, particularly in sub-Saharan Africa where tubal damage following pelvic infection is the commonest cause. Objectives: This study aimed to assess contribution of laparoscopy as a diagnostic and therapeutic tool in infertile women in our setting. Methods: A descriptive review of complete medical records of 208 women who underwent laparoscopy at the Gynaecology Unit of Yaoundé General Hospital from December 2007 to December 2012. Results: Two hundred and eight women were enrolled in this study. Mean age was 32.6 ± 11.25 years. Infertility was secondary in 71.6% of cases;125 (60.1%) women were married and 116 (55.8%) had a positive serology of Chlamydia trachomatis infection. The most frequent findings during diagnostic laparoscopy were: pelvic adhesions (83.7%), hydrosalpinx (21.6%), pyosalpinx (4.8%), perihepatic adhesions (25.5%), uterine fibromas (22.6%), pelvic endometriosis (13%) and ovarian abnormalities (10.1%). The surgical procedures during laparoscopy were: adhesiolysis (79.7%), tuboplasty (35.0%), salpingectomy (8.2%), ovarian cystectomy (5.8%) and myomectomy (1.9%). Three (1.4%) cases of uterine perforation and 1 (0.5%) case of laparoscopy conversion to laparotomy were observed. Conclusion: Diagnostic laparoscopy revealed that tubal lesions and pelvic adhesions were still the major causes of female infertility in developing countries. Adhesiolysis and tuboplasty were the most frequently performed surgical procedures during laparoscopy. Therefore, training in endoscopic surgery should be regarded as an important issue in developing countries.展开更多
文摘<strong>Background:</strong><span style="font-family:Verdana;"> The SARS-CoV-2 and associated corona virus disease COVID-19</span><span style="font-family:Verdana;"> ha</span><span style="font-family:Verdana;">ve</span><span style="font-family:Verdana;"> been declared a pandemic having a poor prognosis among individuals with debilitating conditions and those who are immune</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">compromised. Current evidence is however limited on maternal and fetal transmission and pregnancy outcomes. We aimed to describe the pattern of SARS-CoV-2 infection and outcomes in a group of pregnant women followed</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">up at a tertiary care unit in Cameroon. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">This was an observational study conducted over a period of 3 months (April 1</span></span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">to June 30, 2020) at the Yaounde Central Hospital. All pregnant women who were tested positive for SARS-CoV-2 and who provided a signed written informed consent were included in the study. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">Out of 83 pregnant women who presented with symptoms suspicious of COVID-19, 25 were tested positive. The median age of these women was 31 (27 </span></span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;"> 35)</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">years. A total of 76% consulted within 6 days of onset of symptoms and 68% had a gestational age greater than 28 weeks. The most comm</span><span style="font-family:Verdana;">on </span><span style="font-family:Verdana;">presenting complaint was fever (88%). All 25 pregnant women who </span></span><span style="font-family:Verdana;">were </span><span style="font-family:Verdana;">tested posit</span><span style="font-family:Verdana;">i</span><span style="font-family:Verdana;">ve for COVID-19 were followed up with 9/25 deliveries registered. There were two intra-uterine f</span><span style="font-family:Verdana;">e</span><span style="font-family:Verdana;">tal death</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> and seven live births. All the live birth babies </span><span style="font-family:Verdana;">were </span><span style="font-family:""><span style="font-family:Verdana;">tested negative on Real Time-Polymerase Chain Reaction (RT-PCR) testing which was performed after birth. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">Deliverance of live and SARS-CoV-2 negative babies from COVID-19 pregnant women is possible.</span></span>
文摘Background: Infertility is a global problem, but the highest prevalence is in low resource countries, particularly in sub-Saharan Africa where tubal damage following pelvic infection is the commonest cause. Objectives: This study aimed to assess contribution of laparoscopy as a diagnostic and therapeutic tool in infertile women in our setting. Methods: A descriptive review of complete medical records of 208 women who underwent laparoscopy at the Gynaecology Unit of Yaoundé General Hospital from December 2007 to December 2012. Results: Two hundred and eight women were enrolled in this study. Mean age was 32.6 ± 11.25 years. Infertility was secondary in 71.6% of cases;125 (60.1%) women were married and 116 (55.8%) had a positive serology of Chlamydia trachomatis infection. The most frequent findings during diagnostic laparoscopy were: pelvic adhesions (83.7%), hydrosalpinx (21.6%), pyosalpinx (4.8%), perihepatic adhesions (25.5%), uterine fibromas (22.6%), pelvic endometriosis (13%) and ovarian abnormalities (10.1%). The surgical procedures during laparoscopy were: adhesiolysis (79.7%), tuboplasty (35.0%), salpingectomy (8.2%), ovarian cystectomy (5.8%) and myomectomy (1.9%). Three (1.4%) cases of uterine perforation and 1 (0.5%) case of laparoscopy conversion to laparotomy were observed. Conclusion: Diagnostic laparoscopy revealed that tubal lesions and pelvic adhesions were still the major causes of female infertility in developing countries. Adhesiolysis and tuboplasty were the most frequently performed surgical procedures during laparoscopy. Therefore, training in endoscopic surgery should be regarded as an important issue in developing countries.
