Impact statement.COVID-19 remains an ongoing threat to public health,and reliable,continuous disease monitoring programs are essential for preventing future surges of infection.However,without mandated COVID-19 testin...Impact statement.COVID-19 remains an ongoing threat to public health,and reliable,continuous disease monitoring programs are essential for preventing future surges of infection.However,without mandated COVID-19 testing,accurate data of confirmed cases are unavailable.Instead,COVID-19 viruses may be tracked via wastewater samples from sewage manholes in areas of high social connectivity,where captured viral RNA data are biomarkers useful for monitoring and predicting community-level COVID-19 prevalence through machine learning techniques.We construct a prediction model of high sensitivity and specificity to provide evidence of significant underreporting of COVID-19 cases for the time period following the lifting of testing mandates.展开更多
基金supported by the Centers for Disease Control and Prevention under Grant No.NU50CK000510.
文摘Impact statement.COVID-19 remains an ongoing threat to public health,and reliable,continuous disease monitoring programs are essential for preventing future surges of infection.However,without mandated COVID-19 testing,accurate data of confirmed cases are unavailable.Instead,COVID-19 viruses may be tracked via wastewater samples from sewage manholes in areas of high social connectivity,where captured viral RNA data are biomarkers useful for monitoring and predicting community-level COVID-19 prevalence through machine learning techniques.We construct a prediction model of high sensitivity and specificity to provide evidence of significant underreporting of COVID-19 cases for the time period following the lifting of testing mandates.
