Introduction:3D bio-printing technology<sup>[1-3]</sup>(Figure 1)capable of dispensing live cells,soluble factors,and phase-changing hydrogel in a desired pattern,has great potential in creating 3D tissu...Introduction:3D bio-printing technology<sup>[1-3]</sup>(Figure 1)capable of dispensing live cells,soluble factors,and phase-changing hydrogel in a desired pattern,has great potential in creating 3D tissue.However,maintaining the viability of a thick tissue structure during tissue growth and maturation is challenging due to lack of adequate vascular perfusion.In a simple tissue model with展开更多
基金funded by the American Heart Association Scientist Development Grant SDG12050083National Institutes of Health grant R21 HL102773
文摘Introduction:3D bio-printing technology<sup>[1-3]</sup>(Figure 1)capable of dispensing live cells,soluble factors,and phase-changing hydrogel in a desired pattern,has great potential in creating 3D tissue.However,maintaining the viability of a thick tissue structure during tissue growth and maturation is challenging due to lack of adequate vascular perfusion.In a simple tissue model with