Biliary strictures are caused by both benign and malignant pathologies.Although up to 30%of biliary strictures are identified as benign,the vast majority are malignant with two major malignancies,namely pancreatic ade...Biliary strictures are caused by both benign and malignant pathologies.Although up to 30%of biliary strictures are identified as benign,the vast majority are malignant with two major malignancies,namely pancreatic adenocarcinoma and cholangiocarcinoma(CC)[1].Accurate diagnosis and precise localization play a vital role in the prognosis and management of the disease[2].In this study we primarily focused on the diagnosis of CC.The highest incidence of CC is in northeastern Thailand,where the incidence is found to be 100/100000 in males and 50/100000 in females.In Western countries,it is approximately(0.5–2.0)/100000 individuals[3].CC is most often diagnosed between the ages of 70 and 80 years[4].The prognosis of biliary malignancies is dismal with overall five-year survival as low as 10%[5].展开更多
基金supported by a grant from MH CZ–DRO(FNOl,00098892)。
文摘Biliary strictures are caused by both benign and malignant pathologies.Although up to 30%of biliary strictures are identified as benign,the vast majority are malignant with two major malignancies,namely pancreatic adenocarcinoma and cholangiocarcinoma(CC)[1].Accurate diagnosis and precise localization play a vital role in the prognosis and management of the disease[2].In this study we primarily focused on the diagnosis of CC.The highest incidence of CC is in northeastern Thailand,where the incidence is found to be 100/100000 in males and 50/100000 in females.In Western countries,it is approximately(0.5–2.0)/100000 individuals[3].CC is most often diagnosed between the ages of 70 and 80 years[4].The prognosis of biliary malignancies is dismal with overall five-year survival as low as 10%[5].