Objective To observe the effects of chronic emotional stress on the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) and malonialdehyde (MDA) level in female rats’ brain. Methods The rats ...Objective To observe the effects of chronic emotional stress on the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) and malonialdehyde (MDA) level in female rats’ brain. Methods The rats were randomly divided into 4 groups: normal control group (group N), emotional stress group (group E), emotional stress + pregnancy group (group E+P) and regularly drinking group (group R). Emotional stress in rats was induced by training rats with empty drinking bottles. Having been finished the stress procedure, the brain was taken out and homogenized. Then the activities of SOD, GSH-Px and MDA level were measured. Results Compared to group N, both the activities of SOD in brain tissues of group E and group E+P were significantly decreased ( P <0.05 and P <0.01, respectively) while the MDA level increased ( P <0.05). However, the extent of changes in group E+P was more obvious than that in E. GSH-Px activities in E+P and E were significantly changed. However, the GSH-Px activity in E+P was decreased ( P <0.05) while the activity in E increased ( P <0.05).Conclusion The chronic emotional stress can reduce the antioxidative system by decreasing the antioxidative enzyme activity and potentiating the lipid peroxidation in the brain. It is also suggested that the combination of emotional stress and pregnancy can augment the oxidative damage in rats’ brain.展开更多
Urban Ethics in the Anthropocene:The Moral Dimensions of Six Emerging Conditions in Contemporary Urbanism Author:Jeffrey K H Chan Year:2019 Publisher:Palgrave Macmillan,Singapore ISBN:9789811303074(in English)Several ...Urban Ethics in the Anthropocene:The Moral Dimensions of Six Emerging Conditions in Contemporary Urbanism Author:Jeffrey K H Chan Year:2019 Publisher:Palgrave Macmillan,Singapore ISBN:9789811303074(in English)Several recent reports show how pertinent the issue of burgeoning urbanism is.A 2022 report posits that 75%of China's population will be urbanized by 2030 and Chinese policymakers will have a significant task in managing the heightened CO_(2) emissions(Sandalow et al.,2022).展开更多
文摘Objective To observe the effects of chronic emotional stress on the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) and malonialdehyde (MDA) level in female rats’ brain. Methods The rats were randomly divided into 4 groups: normal control group (group N), emotional stress group (group E), emotional stress + pregnancy group (group E+P) and regularly drinking group (group R). Emotional stress in rats was induced by training rats with empty drinking bottles. Having been finished the stress procedure, the brain was taken out and homogenized. Then the activities of SOD, GSH-Px and MDA level were measured. Results Compared to group N, both the activities of SOD in brain tissues of group E and group E+P were significantly decreased ( P <0.05 and P <0.01, respectively) while the MDA level increased ( P <0.05). However, the extent of changes in group E+P was more obvious than that in E. GSH-Px activities in E+P and E were significantly changed. However, the GSH-Px activity in E+P was decreased ( P <0.05) while the activity in E increased ( P <0.05).Conclusion The chronic emotional stress can reduce the antioxidative system by decreasing the antioxidative enzyme activity and potentiating the lipid peroxidation in the brain. It is also suggested that the combination of emotional stress and pregnancy can augment the oxidative damage in rats’ brain.
文摘Urban Ethics in the Anthropocene:The Moral Dimensions of Six Emerging Conditions in Contemporary Urbanism Author:Jeffrey K H Chan Year:2019 Publisher:Palgrave Macmillan,Singapore ISBN:9789811303074(in English)Several recent reports show how pertinent the issue of burgeoning urbanism is.A 2022 report posits that 75%of China's population will be urbanized by 2030 and Chinese policymakers will have a significant task in managing the heightened CO_(2) emissions(Sandalow et al.,2022).
