How the subduction direction of the Paleo-Pacific plate beneath the Eurasian plate changes in the Early Cretaceous remains highly controversial due to the disappearance of the subducted oceanic plate.Intraplate deform...How the subduction direction of the Paleo-Pacific plate beneath the Eurasian plate changes in the Early Cretaceous remains highly controversial due to the disappearance of the subducted oceanic plate.Intraplate deformation structures in the east Asian continent,however,provide excellent opportunities for reconstructing paleostress fields in continental interior in relation to the Paleo-Pacific/Eurasian plate interaction.Anisotropy of magnetic susceptibility(AMS),geological,and geochronological analyses of post-kinematic mafic dykes intruding the detachment fault zone of the Wulian metamorphic core complex(WL MCC)in Jiaodong Peninsula exemplify emplacement of mantle-sourced dykes in a WNW-ESE(301°-121°)oriented tectonic extensional setting at ca.120 Ma.In combination with the results from our previous kinematic analysis of the MCC,a ca.21°clockwise change in the direction of intraplate extension is obtained for early(135-122 Ma)extensional exhumation of the MCC to late(122-108 Ma)emplacement of the dykes.Such a change is suggested to be related to the variation in subduction direction of the Paleo-Pacific plate beneath the Eurasian plate,from westward(pre-122 Ma)to west-northwestward(post-122 Ma).展开更多
Due to the excellent optoelectronic properties,fast response time,outstanding power efficiency and high stability,micro-LED plays an increasingly important role in the new generation of display technology compared wit...Due to the excellent optoelectronic properties,fast response time,outstanding power efficiency and high stability,micro-LED plays an increasingly important role in the new generation of display technology compared with LCD and OLED display.This paper mainly introduces the preparation methods of the GaN-based micro-LED array,the optoelectronic characteristics,and several key technologies to achieve full-color display,such as transfer printing,color conversion by quantum dot and local strain engineering.展开更多
TiO2‐supported Pd‐Sb bimetallic catalysts were prepared and evaluated for the direct synthesis of H2O2 at ambient pressure.The addition of Sb to Pd significantly enhanced catalytic performance,and a Pd50Sb catalyst ...TiO2‐supported Pd‐Sb bimetallic catalysts were prepared and evaluated for the direct synthesis of H2O2 at ambient pressure.The addition of Sb to Pd significantly enhanced catalytic performance,and a Pd50Sb catalyst showed the greatest selectivity of up to 73%.Sb promoted the dispersion of Pd on TiO2,as evidenced by transmission electron microscopy and X‐ray diffraction.X‐ray photoelectron spectroscopy indicated that the oxidation of Pd was suppressed by Sb.In addition,Sb2O3 layers were formed and partially wrapped the surfaces of Pd catalysts,thus suppressing the activation of H2 and subsequent hydrogenation of H2O2.In situ diffuse reflection infrared Fourier transform spectroscopy for CO adsorption suggested that Sb homogenously located on the surface of Pd‐Sb catalysts and isolated contiguous Pd sites,resulting in the rise of the ratio of Pd monomer sites that are favorable for H2O2 formation.As a result,the Sb modified Pd surfaces significantly enhanced the non‐dissociative activation of O2 and H2O2 selectivity.展开更多
Electrochemical oxygen evolution reaction (OER) is a main efficiency bottleneck of water electrolysis.Commercial ruthenium oxide (RuO_(2)) catalyst displays remarkable activities but poor stability for OER.The instabi...Electrochemical oxygen evolution reaction (OER) is a main efficiency bottleneck of water electrolysis.Commercial ruthenium oxide (RuO_(2)) catalyst displays remarkable activities but poor stability for OER.The instability stems from lattice oxygen oxidation,resulting in the oxidation of Ru^(4+) to soluble Ru^(4+)(x>4) species.Herein,we redirect dynamic structural evolution of Ru-based catalysts through introducing oxidized nickel (Ni) components.By virtue of comprehensive structural characterizations,such as high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM),X-ray photoelectron spectroscopy (XPS),operando Raman and so forth,it is demonstrated that when the atomic content of Ni exceeds that of ruthenium (Ru),the Ni components can efficiently inhibit the Ru^(4+) oxidation and structural collapse.Density functional theory (DFT) calculations suggest that the introduction of Ni component hinders the formation of oxygen vacancies,and makes lattice oxygen mediated mechanism turn to adsorbate evolution mechanism,which eventually improves the stability.The optimized nickel-contained RuO_(2) catalyst delivers an effective reactivity with an overpotential of less than 215 m V to attain 10 m A cm^(-2) and remarkable stability with only 5 mV increment after 5000 potential cycles.This work provides insights into the origin of dynamic structural evolution of transition-metalmodified RuO_(2) electrocatalysts.展开更多
Great attention has been paid to cofacial porphyrins due to their many unique advantages over their monomeric analogs.However,their synthesis is usually complicated.In this work,a facile impregnation method for prepar...Great attention has been paid to cofacial porphyrins due to their many unique advantages over their monomeric analogs.However,their synthesis is usually complicated.In this work,a facile impregnation method for preparing heterogenized,cofacially stacked porphyrins is proposed.An anionic porphyrin is introduced as an underlayer for immobilization of cationic cobalt porphyrin via electrostatic force.The metal center of the underlying molecule contributes to the electronic structure of the upper cationic cobalt porphyrin.Screening reveals the anionic iron porphyrin to be the most efficient underlayer molecule,lowering the activation energy barrier of CO_(2) electroreduction,with an improved turnover frequency by 74%to8.0 s~(-1)at-0.6 V versus RHE.展开更多
Direct synthesis of H_(2)O_(2)from H_(2) and O_(2)via heterogeneous catalysis is an environmentally friendly and atomically economic alternative to the traditional anthraquinone oxidation(AO)process.Optimizing the ele...Direct synthesis of H_(2)O_(2)from H_(2) and O_(2)via heterogeneous catalysis is an environmentally friendly and atomically economic alternative to the traditional anthraquinone oxidation(AO)process.Optimizing the electronic and geometric structures of the active metals to break the current limitations of hydrogenation rate and H_(2)O_(2)selectivity is a promising and challenging topic.In this study,a series of Pd-Au bimetallic catalysts supported on TiO_(2)with a metal loading of 3.0 wt%and a constant Pd/Au molar ratio(Pd:Au=2:1)were prepared.The catalysts were reduced in H_(2) at different temperatures(473,573 and 673 K),and their catalytic activity for the direct H_(2)O_(2)synthesis were evaluated at 283 K and 0.1MPa.H_(2) reduced Pd-Au catalysts exhibited superior performance in direct H_(2)O_(2)synthesis.The maximum H_(2)O_(2)selectivity of 87.7%and H_(2)O_(2)yield of 3116.4 mmol h^(−1) gPd^(−1) were achieved over the Pd_(2.0)Au_(1.0)-573 catalyst with a H_(2) conversion of 12.8%.The tailored local chemical environment caused by H_(2) reduction creates a balanced ratio of Pd0 and PdO_(x) sites,thus improving the selectivity towards H_(2)O_(2).This work developed an effective strategy for fabrication of highly active and stable Pd-based H_(2)O_(2)synthesis catalysts with high H_(2)O_(2)yield.展开更多
Post-resection recurrence remains a severe problem in melanoma treatment.New therapeutic strategies,such as chemodynamic therapy(CDT),exhibit high specificity and responsiveness,demonstrating potential to elicit antit...Post-resection recurrence remains a severe problem in melanoma treatment.New therapeutic strategies,such as chemodynamic therapy(CDT),exhibit high specificity and responsiveness,demonstrating potential to elicit antitumor immune responses by triggering immunogenic cell death(ICD).However,the efficacy of CDT still faces challenges from the immunosuppressive tumor microenvironment(TME)characterized by elevated lactate levels.Herein,we propose a strategy to construct an immunomodulatory hydrogel to synergistically reprogram tumor-associated macrophages and amplify ICD to inhibit melanoma recurrence after surgery.The hyaluronic acid hydrogel containing borosilicate glasses(BGs)and Fe_(3)O_(4) nanoparticles(HBF hydrogel)are obtained,which can neutralize tumor acidity to reprogram macrophages to M1 phenotype.Furthermore,the HBF hydrogel induces reactive oxygen species production in melanoma cells,which could induce ICD through CDT and stimulate strong antitumor immune responses,thereby promoting tumor immunotherapy.The cooperative ICD induced by CDT and immunosuppressive TME remodeling leads to effective suppression of tumor recurrence.This work provides a promising strategy for immunomodulation-enhanced melanoma therapy through the fabrication of hydrogel to prevent postsurgical tumor recurrence.展开更多
Rain has a strong attenuation effect on light,which can impact the performance of visible light communication(VLC).In this paper,we addressed the crucial challenge of implementing high-speed VLC systems in rainy envir...Rain has a strong attenuation effect on light,which can impact the performance of visible light communication(VLC).In this paper,we addressed the crucial challenge of implementing high-speed VLC systems in rainy environments by focusing on the performance of different wavelengths under varying rain conditions.By analyzing the attenuation characteristics of four laser diodes at different wavelengths under various artificial rain environments,we developed a high-speed VLC system optimized for rainy channel high-speed visible light communication by employing the orthogonal frequency-division multiplexing modulation scheme.By integrating channel-adaptive pre-equalization and bit-loading algorithms,our system optimized signal transmission in rainy channels,enabling an aggregated data rate exceeding 30 Gbps,which was the highest reported data rate for VLC in rainy channels,to the best of our knowledge.展开更多
The regeneration of alveolar bone is still clinical challenge,particularly accompanied with diabetes,causing metabolic disorder with a protracted low-grade inflammatory phenotype.As a result,the anticipated loading of...The regeneration of alveolar bone is still clinical challenge,particularly accompanied with diabetes,causing metabolic disorder with a protracted low-grade inflammatory phenotype.As a result,the anticipated loading of biomaterials is highly suspicious in spontaneous modulation of cells function,which is mostly disturbed by constant inflammation.In this study,we developed glucose and hydrogen peroxide dual-responsive borosilicate glass(BSG)scaffolds loaded with epigallocatechin gallate(EGCG)to synergistically modulate the abnormal inflammation of diabetic alveolar bone defects.It was found that the release of EGCG by BSG could directly regulate the shift of macrophages from M1 to the M2 phenotype by promoting autophagy and lessening the inhibition of autophagic flux.Moreover,EGCG can also indirectly regulate the polarization phenotype of macrophages by reducing the activation of NF-κb in stem cells and restoring its immunoregulatory capacity.Therefore,the addition of EGCG to BSG scaffold in diabetes allows for a more striking modulation of the macrophage phenotype in a timely manner.The altered macrophage phenotype reduces local inflammation and thus increases the ability to repair diabetic alveolar bone,showing promise for the treatment of alveolar defect in diabetic patients.展开更多
In this work,a blue gallium nitride(GaN)micro-light-emitting-diode(micro-LED)-based underwater wireless optical communication(UWOC)system was built,and UWOCs with varied Maalox,chlorophyll,and sea salt concentrations ...In this work,a blue gallium nitride(GaN)micro-light-emitting-diode(micro-LED)-based underwater wireless optical communication(UWOC)system was built,and UWOCs with varied Maalox,chlorophyll,and sea salt concentrations were studied.Data transmission performance of the UWOC and the influence of light attenuation were investigated systematically.Maximum data transmission rates at the distance of 2.3 m were 933,800,910,and 790 Mbps for experimental conditions with no impurity,200.48 mg/m3 Maalox,12.07 mg/m3 chlorophyll,and 5 kg/m3 sea salt,respectively,much higher than previously reported systems with commercial LEDs.It was found that increasing chlorophyll,Maalox,and sea salt concentrations in water resulted in an increase of light attenuation,which led to the performance degradation of the UWOC.Further analysis suggests two light attenuation mechanisms,e.g.,absorption by chlorophyll and scattering by Maalox,are responsible for the decrease of maximum data rates and the increase of bit error rates.Based on the absorption and scattering models,excellent fitting to the experimental attenuation coefficient can be achieved,and light attenuation by absorption and scattering at different wavelengths was also investigated.We believe this work is instructive apply UWOC for practical applications.展开更多
Herein we proposed a data-driven high-throughput principle to screen high-performance single-atom materials for hydrogen evolution reaction(HER)and hydrogen sensing by combing the theoretical computations and a topolo...Herein we proposed a data-driven high-throughput principle to screen high-performance single-atom materials for hydrogen evolution reaction(HER)and hydrogen sensing by combing the theoretical computations and a topology-based multi-scale convolution kernel machine learning algorithm.After the rational training by 25 groups of data and prediction of all 168 groups of single-atom materials for HER and sensing,respectively,a high prediction accuracy(>0.931 R^(2) score)was achieved by our model.Results show that the promising HER catalysts include Pt atoms in C_(4) and Sc atoms in C_(1)N_(3) coordination environment.Moreover,Y atoms in C_(4) coordination environment and Cd atoms in C_(2)N_(2)-ortho coordination environment were predicted with great potential as hydrogen sensing materials.This method provides a way to accelerate the discovery of innovative materials by avoiding the time-consuming empirical principles in experiments.展开更多
Due to the bandwidth limitation of the ultraviolet-C(UV-C) optical communication system and strong channel attenuation, it is difficult to transmit high-frequency signals. In this paper, the temporal ghost imaging(TGI...Due to the bandwidth limitation of the ultraviolet-C(UV-C) optical communication system and strong channel attenuation, it is difficult to transmit high-frequency signals. In this paper, the temporal ghost imaging(TGI) algorithm was first applied to the UV-C communication experimentally, and we realized the transmission of a 4 GHz signal through 95.34 MHz system bandwidth. The study indicates that the TGI algorithm can significantly improve the signal-to-noise ratio(SNR) compared with the on–off keying method. Our research provides a new approach for alleviating transmission frequency limitation due to poor SNR and insufficient hardware bandwidth.展开更多
Maximizing atomic utilization of precious metalbased catalysts is of great significance in heterogeneous catalysis,also becoming a useful strategy to develop efficient electrocatalysts for hydrogen evolution reaction(...Maximizing atomic utilization of precious metalbased catalysts is of great significance in heterogeneous catalysis,also becoming a useful strategy to develop efficient electrocatalysts for hydrogen evolution reaction(HER).Although the dispersion of platinum(Pt)as single atoms(SAs)has increasingly been used in the design of HER electrocatalysts,it is still controversial if the SAs possess higher reactivity relative to the nanoparticles with identical atom loading.展开更多
Multicolor series connection micro-LED arrays with emission wavelengths of violet, blue, green, and yellow were fabricated, and their optoelectronic properties and communication performances were investigated. The des...Multicolor series connection micro-LED arrays with emission wavelengths of violet, blue, green, and yellow were fabricated, and their optoelectronic properties and communication performances were investigated. The designed series connection micro-LED array exhibited the light output power of multiple milliwatts, whereas mostly keeping a slightly reduced modulation bandwidth, thus, enabling a higher signal-to-noise ratio compared to a single pixel and showing superior performance in the field of long-distance visible light communication(VLC). The achievable data rates of 400-, 451-, 509-, and 556-nm micro-LED arrays using bit/power loading orthogonal frequency division multiplexing were 5.71, 4.86, 4.39, and 0.82 Gbps, respectively. The aggregate data rate of 15.78 Gbps was achieved for the proof-of-concept wavelength division multiplexing system under a transmission distance of 13 m, which was the best data rate-distance product performance for the LED-based VLC to the best of our knowledge. In addition, the long-distance VLC based on yellow micro-LED was also demonstrated for the first time in this paper.展开更多
Visible light communication(VLC)based on the micro light emitting diode(micro-LED)has attracted increasing attention owing to its high bandwidth,low power consumption,and high security.Compared with semi-polar or non-...Visible light communication(VLC)based on the micro light emitting diode(micro-LED)has attracted increasing attention owing to its high bandwidth,low power consumption,and high security.Compared with semi-polar or non-polar micro-LEDs,the commercial polar micro-LED has the advantages of low cost and more mature epitaxy technique.In this study,green micro-LEDs with different indium tin oxide(ITO)sizes are fabricated based on the commercial c-plane LED epitaxial wafer.The transmission performance of 80,100,and 150μm devices has been studied in detail.A partial pre-equalization scheme is utilized to increase data rates.Finally,the VLC system with a 100μm green micro-LED as the transmitter could achieve a maximum data rate of 3.59 Gbit/s.Such a result will be beneficial to promote the further development of low-cost,high-speed VLC devices in the future.展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos:42130801,41430211,90814006,and 42072226)the“Deep-time Digital Earth”Science and Technology Leading Talents Team Funds for the Central Universities for the Frontiers Science Center for Deep-time Digital Earth,CUGB(Fundamental Research Funds for the Central UniversitiesGrant No:2652023001).
文摘How the subduction direction of the Paleo-Pacific plate beneath the Eurasian plate changes in the Early Cretaceous remains highly controversial due to the disappearance of the subducted oceanic plate.Intraplate deformation structures in the east Asian continent,however,provide excellent opportunities for reconstructing paleostress fields in continental interior in relation to the Paleo-Pacific/Eurasian plate interaction.Anisotropy of magnetic susceptibility(AMS),geological,and geochronological analyses of post-kinematic mafic dykes intruding the detachment fault zone of the Wulian metamorphic core complex(WL MCC)in Jiaodong Peninsula exemplify emplacement of mantle-sourced dykes in a WNW-ESE(301°-121°)oriented tectonic extensional setting at ca.120 Ma.In combination with the results from our previous kinematic analysis of the MCC,a ca.21°clockwise change in the direction of intraplate extension is obtained for early(135-122 Ma)extensional exhumation of the MCC to late(122-108 Ma)emplacement of the dykes.Such a change is suggested to be related to the variation in subduction direction of the Paleo-Pacific plate beneath the Eurasian plate,from westward(pre-122 Ma)to west-northwestward(post-122 Ma).
基金National Natural Science Foundation of China(NSFC)(61974031,61705041 and 61571135)Shanghai Sailing Program(17YF1429100)+2 种基金Shanghai Technical Standard Program(18DZ2206000)State Key Laboratory of Intense Pulsed Radiation Simulation and Effect Funding(SKLIPR1607)National Key Research and Development Program of China(2017YFB0403603).
文摘Due to the excellent optoelectronic properties,fast response time,outstanding power efficiency and high stability,micro-LED plays an increasingly important role in the new generation of display technology compared with LCD and OLED display.This paper mainly introduces the preparation methods of the GaN-based micro-LED array,the optoelectronic characteristics,and several key technologies to achieve full-color display,such as transfer printing,color conversion by quantum dot and local strain engineering.
基金supported by the National Natural Science Foundation of China(91534127,U1463205)the Innovation Scientists and Technicians Troop Construction Projects of Henan Provincethe Chinese Education Ministry 111 Project(B08021)~~
文摘TiO2‐supported Pd‐Sb bimetallic catalysts were prepared and evaluated for the direct synthesis of H2O2 at ambient pressure.The addition of Sb to Pd significantly enhanced catalytic performance,and a Pd50Sb catalyst showed the greatest selectivity of up to 73%.Sb promoted the dispersion of Pd on TiO2,as evidenced by transmission electron microscopy and X‐ray diffraction.X‐ray photoelectron spectroscopy indicated that the oxidation of Pd was suppressed by Sb.In addition,Sb2O3 layers were formed and partially wrapped the surfaces of Pd catalysts,thus suppressing the activation of H2 and subsequent hydrogenation of H2O2.In situ diffuse reflection infrared Fourier transform spectroscopy for CO adsorption suggested that Sb homogenously located on the surface of Pd‐Sb catalysts and isolated contiguous Pd sites,resulting in the rise of the ratio of Pd monomer sites that are favorable for H2O2 formation.As a result,the Sb modified Pd surfaces significantly enhanced the non‐dissociative activation of O2 and H2O2 selectivity.
基金supported by the National Natural Science Foundation of China (21978278, 21838003 and 91834301)the Shanghai Scientific and Technological Innovation Project (18JC1410500 and 19JC1410400)the Fundamental Research Funds for the Central Universities (222201718002)。
文摘Electrochemical oxygen evolution reaction (OER) is a main efficiency bottleneck of water electrolysis.Commercial ruthenium oxide (RuO_(2)) catalyst displays remarkable activities but poor stability for OER.The instability stems from lattice oxygen oxidation,resulting in the oxidation of Ru^(4+) to soluble Ru^(4+)(x>4) species.Herein,we redirect dynamic structural evolution of Ru-based catalysts through introducing oxidized nickel (Ni) components.By virtue of comprehensive structural characterizations,such as high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM),X-ray photoelectron spectroscopy (XPS),operando Raman and so forth,it is demonstrated that when the atomic content of Ni exceeds that of ruthenium (Ru),the Ni components can efficiently inhibit the Ru^(4+) oxidation and structural collapse.Density functional theory (DFT) calculations suggest that the introduction of Ni component hinders the formation of oxygen vacancies,and makes lattice oxygen mediated mechanism turn to adsorbate evolution mechanism,which eventually improves the stability.The optimized nickel-contained RuO_(2) catalyst delivers an effective reactivity with an overpotential of less than 215 m V to attain 10 m A cm^(-2) and remarkable stability with only 5 mV increment after 5000 potential cycles.This work provides insights into the origin of dynamic structural evolution of transition-metalmodified RuO_(2) electrocatalysts.
基金sponsored by the Program for Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learning and Shanghai Sailing Program(No.19YF1410600)the Young Scientists Fund of the National Natural Science Foundation of China(No.21905240)the State Key Laboratory of Marine Pollution(SKLMP)Seed Collaborative Research Fund。
文摘Great attention has been paid to cofacial porphyrins due to their many unique advantages over their monomeric analogs.However,their synthesis is usually complicated.In this work,a facile impregnation method for preparing heterogenized,cofacially stacked porphyrins is proposed.An anionic porphyrin is introduced as an underlayer for immobilization of cationic cobalt porphyrin via electrostatic force.The metal center of the underlying molecule contributes to the electronic structure of the upper cationic cobalt porphyrin.Screening reveals the anionic iron porphyrin to be the most efficient underlayer molecule,lowering the activation energy barrier of CO_(2) electroreduction,with an improved turnover frequency by 74%to8.0 s~(-1)at-0.6 V versus RHE.
基金supported by the National Natural Science Foundation of China(Nos.91934302 and 22178110)the Dean/Opening Project of Guangxi Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology(No.2020K001)the Project of the Department of Science and Technology of Sichuan Province(No.2023YFQ0086).
文摘Direct synthesis of H_(2)O_(2)from H_(2) and O_(2)via heterogeneous catalysis is an environmentally friendly and atomically economic alternative to the traditional anthraquinone oxidation(AO)process.Optimizing the electronic and geometric structures of the active metals to break the current limitations of hydrogenation rate and H_(2)O_(2)selectivity is a promising and challenging topic.In this study,a series of Pd-Au bimetallic catalysts supported on TiO_(2)with a metal loading of 3.0 wt%and a constant Pd/Au molar ratio(Pd:Au=2:1)were prepared.The catalysts were reduced in H_(2) at different temperatures(473,573 and 673 K),and their catalytic activity for the direct H_(2)O_(2)synthesis were evaluated at 283 K and 0.1MPa.H_(2) reduced Pd-Au catalysts exhibited superior performance in direct H_(2)O_(2)synthesis.The maximum H_(2)O_(2)selectivity of 87.7%and H_(2)O_(2)yield of 3116.4 mmol h^(−1) gPd^(−1) were achieved over the Pd_(2.0)Au_(1.0)-573 catalyst with a H_(2) conversion of 12.8%.The tailored local chemical environment caused by H_(2) reduction creates a balanced ratio of Pd0 and PdO_(x) sites,thus improving the selectivity towards H_(2)O_(2).This work developed an effective strategy for fabrication of highly active and stable Pd-based H_(2)O_(2)synthesis catalysts with high H_(2)O_(2)yield.
基金National Key Research and Development Program of China (2021YFC2400500)National Natural Science Foundation of China (52173271, 52361165659, and 52221006)Beijing Outstanding Young Scientist Program(BJJWZYJH01201910010024)。
文摘Post-resection recurrence remains a severe problem in melanoma treatment.New therapeutic strategies,such as chemodynamic therapy(CDT),exhibit high specificity and responsiveness,demonstrating potential to elicit antitumor immune responses by triggering immunogenic cell death(ICD).However,the efficacy of CDT still faces challenges from the immunosuppressive tumor microenvironment(TME)characterized by elevated lactate levels.Herein,we propose a strategy to construct an immunomodulatory hydrogel to synergistically reprogram tumor-associated macrophages and amplify ICD to inhibit melanoma recurrence after surgery.The hyaluronic acid hydrogel containing borosilicate glasses(BGs)and Fe_(3)O_(4) nanoparticles(HBF hydrogel)are obtained,which can neutralize tumor acidity to reprogram macrophages to M1 phenotype.Furthermore,the HBF hydrogel induces reactive oxygen species production in melanoma cells,which could induce ICD through CDT and stimulate strong antitumor immune responses,thereby promoting tumor immunotherapy.The cooperative ICD induced by CDT and immunosuppressive TME remodeling leads to effective suppression of tumor recurrence.This work provides a promising strategy for immunomodulation-enhanced melanoma therapy through the fabrication of hydrogel to prevent postsurgical tumor recurrence.
基金supported by the National Key Research and Development Program of China(No.2021YFB3601003)。
文摘Rain has a strong attenuation effect on light,which can impact the performance of visible light communication(VLC).In this paper,we addressed the crucial challenge of implementing high-speed VLC systems in rainy environments by focusing on the performance of different wavelengths under varying rain conditions.By analyzing the attenuation characteristics of four laser diodes at different wavelengths under various artificial rain environments,we developed a high-speed VLC system optimized for rainy channel high-speed visible light communication by employing the orthogonal frequency-division multiplexing modulation scheme.By integrating channel-adaptive pre-equalization and bit-loading algorithms,our system optimized signal transmission in rainy channels,enabling an aggregated data rate exceeding 30 Gbps,which was the highest reported data rate for VLC in rainy channels,to the best of our knowledge.
基金supported by the National Key R&D Program of China(2021YFC2400500)National Natural Science Foundation of China(Nos.U2001221 and 32161160327)+1 种基金Shenzhen Science and Technology Program(JCYJ20200109114620793 and JSGGKQTD20210831174330015)Guangdong Basic and Applied Basic Research Foundation(2022B 1515120048 and 2023A1515011727).
文摘The regeneration of alveolar bone is still clinical challenge,particularly accompanied with diabetes,causing metabolic disorder with a protracted low-grade inflammatory phenotype.As a result,the anticipated loading of biomaterials is highly suspicious in spontaneous modulation of cells function,which is mostly disturbed by constant inflammation.In this study,we developed glucose and hydrogen peroxide dual-responsive borosilicate glass(BSG)scaffolds loaded with epigallocatechin gallate(EGCG)to synergistically modulate the abnormal inflammation of diabetic alveolar bone defects.It was found that the release of EGCG by BSG could directly regulate the shift of macrophages from M1 to the M2 phenotype by promoting autophagy and lessening the inhibition of autophagic flux.Moreover,EGCG can also indirectly regulate the polarization phenotype of macrophages by reducing the activation of NF-κb in stem cells and restoring its immunoregulatory capacity.Therefore,the addition of EGCG to BSG scaffold in diabetes allows for a more striking modulation of the macrophage phenotype in a timely manner.The altered macrophage phenotype reduces local inflammation and thus increases the ability to repair diabetic alveolar bone,showing promise for the treatment of alveolar defect in diabetic patients.
基金supported by the National Natural Science Foundation of China(NSFC)(Nos.61705041 and61571135)Shanghai Sailing Program(No.17YF1429100)+2 种基金Shanghai Technical Standard Program(No.18DZ2206000)State Key Laboratory of Intense Pulsed Radiation Simulation and Effect Funding(No.SKLIPR1607)National Key Research and Development Program of China(No.2017YFB0403603)
文摘In this work,a blue gallium nitride(GaN)micro-light-emitting-diode(micro-LED)-based underwater wireless optical communication(UWOC)system was built,and UWOCs with varied Maalox,chlorophyll,and sea salt concentrations were studied.Data transmission performance of the UWOC and the influence of light attenuation were investigated systematically.Maximum data transmission rates at the distance of 2.3 m were 933,800,910,and 790 Mbps for experimental conditions with no impurity,200.48 mg/m3 Maalox,12.07 mg/m3 chlorophyll,and 5 kg/m3 sea salt,respectively,much higher than previously reported systems with commercial LEDs.It was found that increasing chlorophyll,Maalox,and sea salt concentrations in water resulted in an increase of light attenuation,which led to the performance degradation of the UWOC.Further analysis suggests two light attenuation mechanisms,e.g.,absorption by chlorophyll and scattering by Maalox,are responsible for the decrease of maximum data rates and the increase of bit error rates.Based on the absorption and scattering models,excellent fitting to the experimental attenuation coefficient can be achieved,and light attenuation by absorption and scattering at different wavelengths was also investigated.We believe this work is instructive apply UWOC for practical applications.
基金supported by the National Key R&D Program of China (2022YFB3605500 and 2022YFB3605503)the National Natural Science Foundation of China (62074039 and 12004074)+1 种基金China Postdoctoral Science Foundation (2020M681141)the National Postdoctoral Program for Innovative Talents (BX20190070)。
基金supported by the National Natural Science Foundation of China(Nos.52105145 and 12274124)the Shanghai Pilot Program for Basic Research(No.22TQ1400100-6)the Fundamental Research Funds for the Central Universities.
文摘Herein we proposed a data-driven high-throughput principle to screen high-performance single-atom materials for hydrogen evolution reaction(HER)and hydrogen sensing by combing the theoretical computations and a topology-based multi-scale convolution kernel machine learning algorithm.After the rational training by 25 groups of data and prediction of all 168 groups of single-atom materials for HER and sensing,respectively,a high prediction accuracy(>0.931 R^(2) score)was achieved by our model.Results show that the promising HER catalysts include Pt atoms in C_(4) and Sc atoms in C_(1)N_(3) coordination environment.Moreover,Y atoms in C_(4) coordination environment and Cd atoms in C_(2)N_(2)-ortho coordination environment were predicted with great potential as hydrogen sensing materials.This method provides a way to accelerate the discovery of innovative materials by avoiding the time-consuming empirical principles in experiments.
基金This work was supported by the National Natural Science Foundation of China(NSFC)(Nos.61974031 and 61705041)Fudan University-CIOMP Joint Fund(No.FC2020-001)Shanghai Technical Standard Program(No.18DZ2206000).
文摘Due to the bandwidth limitation of the ultraviolet-C(UV-C) optical communication system and strong channel attenuation, it is difficult to transmit high-frequency signals. In this paper, the temporal ghost imaging(TGI) algorithm was first applied to the UV-C communication experimentally, and we realized the transmission of a 4 GHz signal through 95.34 MHz system bandwidth. The study indicates that the TGI algorithm can significantly improve the signal-to-noise ratio(SNR) compared with the on–off keying method. Our research provides a new approach for alleviating transmission frequency limitation due to poor SNR and insufficient hardware bandwidth.
基金supported by the National Natural Science Foundation of China(nos.21838003,91834301,and 21978278)the Shanghai Scientific and Technological Innovation Project(nos.18JC1410500 and 19JC1410400)the Fundamental Research Funds for the Central Universities(no.222201718002).
文摘Maximizing atomic utilization of precious metalbased catalysts is of great significance in heterogeneous catalysis,also becoming a useful strategy to develop efficient electrocatalysts for hydrogen evolution reaction(HER).Although the dispersion of platinum(Pt)as single atoms(SAs)has increasingly been used in the design of HER electrocatalysts,it is still controversial if the SAs possess higher reactivity relative to the nanoparticles with identical atom loading.
基金National Key Research and Development Program of China(2021YFB3601000,2021YFB3601003,2021YFE0105300)National Natural Science Foundation of China(61974031)+1 种基金Science and Technology Commission of Shanghai Municipality(21511101303)Leading-edge Technology Program of Jiangsu Natural Science Foundation(BE2021008-2)。
文摘Multicolor series connection micro-LED arrays with emission wavelengths of violet, blue, green, and yellow were fabricated, and their optoelectronic properties and communication performances were investigated. The designed series connection micro-LED array exhibited the light output power of multiple milliwatts, whereas mostly keeping a slightly reduced modulation bandwidth, thus, enabling a higher signal-to-noise ratio compared to a single pixel and showing superior performance in the field of long-distance visible light communication(VLC). The achievable data rates of 400-, 451-, 509-, and 556-nm micro-LED arrays using bit/power loading orthogonal frequency division multiplexing were 5.71, 4.86, 4.39, and 0.82 Gbps, respectively. The aggregate data rate of 15.78 Gbps was achieved for the proof-of-concept wavelength division multiplexing system under a transmission distance of 13 m, which was the best data rate-distance product performance for the LED-based VLC to the best of our knowledge. In addition, the long-distance VLC based on yellow micro-LED was also demonstrated for the first time in this paper.
基金supported by the National Key Research and Development Program of China(Nos.2021YFE0105300,2021YFB3601000,and 2021YFB3601003)National Natural Science Foundation of China(Nos.61925104,62171137,and 62031011)+2 种基金Major Key Project of PCL(No.PCL2021A14)Technology Commission of Shanghai Municipality(No.21511101303)Leading-edge Technology Program of Jiangsu Natural Science Foundation(No.BE2021008-2).
文摘Visible light communication(VLC)based on the micro light emitting diode(micro-LED)has attracted increasing attention owing to its high bandwidth,low power consumption,and high security.Compared with semi-polar or non-polar micro-LEDs,the commercial polar micro-LED has the advantages of low cost and more mature epitaxy technique.In this study,green micro-LEDs with different indium tin oxide(ITO)sizes are fabricated based on the commercial c-plane LED epitaxial wafer.The transmission performance of 80,100,and 150μm devices has been studied in detail.A partial pre-equalization scheme is utilized to increase data rates.Finally,the VLC system with a 100μm green micro-LED as the transmitter could achieve a maximum data rate of 3.59 Gbit/s.Such a result will be beneficial to promote the further development of low-cost,high-speed VLC devices in the future.
基金the National Natural Science Foundation of China (Nos.61774040,11774170, and 61774042)the Opening project of State Key Laboratory of Functional Materials for Informafics (Shanghai Institute of Microsystem and Information Technolog,Chinese Academy of Sciences),the National Young 1000Talent Plan of China,the Shanghai Municipal Natural Science Foundation (Nos. 16ZR1402500,17ZR1446500,and 17ZR1446600)NTU Start-up grant M4080513,Singapore Ministry of Education (MOE)Tier 1RG199/17,and Shanghai Pujiang Program (No.16PJ1401000).C.C.
