目的:对妇科恶性肿瘤病人经济毒性的影响因素进行范围综述,为制订针对性干预措施提供科学依据。方法:以范围综述方法学为指导框架,系统检索EMbase、PubMed、Cochrane Library、Web of Science、CINAHL 5个英文数据库及中国知网、万方数...目的:对妇科恶性肿瘤病人经济毒性的影响因素进行范围综述,为制订针对性干预措施提供科学依据。方法:以范围综述方法学为指导框架,系统检索EMbase、PubMed、Cochrane Library、Web of Science、CINAHL 5个英文数据库及中国知网、万方数据库、维普数据库、中国生物医学文献数据库4个中文数据库公开发表的关于妇科恶性肿瘤病人经济毒性影响因素的文献,检索时限为建库至2024年3月22日。结果:共纳入16篇文献,其中英文文献15篇,中文文献1篇;宫颈癌、卵巢癌和子宫内膜癌病人经济毒性的主要影响因素包括社会人口学因素、疾病因素、医疗费用因素(直接费用、间接费用和附加费用)、医疗保险因素和其他因素5个方面。结论:妇科恶性肿瘤病人经济毒性受诸多因素影响,分析影响因素有助于高危人群的识别。未来可进一步探索影响妇科恶性肿瘤病人经济毒性的争议因素,为制订经济毒性干预措施提供理论依据。展开更多
High strength aluminum alloy plate has a low elongation at room temperature, which leads to the forming of its components need a high temperature. Liquid or gas is used as the pressure-transfer medium in the existing ...High strength aluminum alloy plate has a low elongation at room temperature, which leads to the forming of its components need a high temperature. Liquid or gas is used as the pressure-transfer medium in the existing flexible mould forming process, the heat resistance of the medium and pressurizing device makes the application of aluminum alloy plate thermoforming restricted. To solve this problem, the existing medium is replaced by the heat-resisting solid granules and the general pressure equipments are applied. Based on the pressure-transfer performance test of the solid granules medium, the feasibility that the assumption of the extended Drucker-Prager linear model can be used in the finite element analysis is proved. The constitutive equation, the yield function and the theoretical forming limit diagram（FLD） of AA7075 sheet are established. Through the finite element numerical simulation of hot granules medium pressure forming（HGMF） process, not only the influence laws of the process parameters, such as forming temperature, the blank-holder gap and the diameter of the slab, on sheet metal forming performance are discussed, but also the broken area of the forming process is analyzed and predicted, which are coincided with the technological test. The conical part whose half cone angle is 15° and relative height H/d0 is 0.57, is formed in one process at 250℃. The HGMF process solves the problems of loading and seal in the existing flexible mould forming process and provides a novel technology for thermoforming of light alloy plate, such as magnesium alloy, aluminium alloy and titanium alloy.展开更多
文摘目的:对妇科恶性肿瘤病人经济毒性的影响因素进行范围综述,为制订针对性干预措施提供科学依据。方法:以范围综述方法学为指导框架,系统检索EMbase、PubMed、Cochrane Library、Web of Science、CINAHL 5个英文数据库及中国知网、万方数据库、维普数据库、中国生物医学文献数据库4个中文数据库公开发表的关于妇科恶性肿瘤病人经济毒性影响因素的文献,检索时限为建库至2024年3月22日。结果:共纳入16篇文献,其中英文文献15篇,中文文献1篇;宫颈癌、卵巢癌和子宫内膜癌病人经济毒性的主要影响因素包括社会人口学因素、疾病因素、医疗费用因素(直接费用、间接费用和附加费用)、医疗保险因素和其他因素5个方面。结论:妇科恶性肿瘤病人经济毒性受诸多因素影响,分析影响因素有助于高危人群的识别。未来可进一步探索影响妇科恶性肿瘤病人经济毒性的争议因素,为制订经济毒性干预措施提供理论依据。
基金Supported by National Natural Science Foundation of China(Grant Nos.51305386,51305385)Hebei Provincial Natural Science Foundation of China(Grant No.E2013203093)
文摘High strength aluminum alloy plate has a low elongation at room temperature, which leads to the forming of its components need a high temperature. Liquid or gas is used as the pressure-transfer medium in the existing flexible mould forming process, the heat resistance of the medium and pressurizing device makes the application of aluminum alloy plate thermoforming restricted. To solve this problem, the existing medium is replaced by the heat-resisting solid granules and the general pressure equipments are applied. Based on the pressure-transfer performance test of the solid granules medium, the feasibility that the assumption of the extended Drucker-Prager linear model can be used in the finite element analysis is proved. The constitutive equation, the yield function and the theoretical forming limit diagram（FLD） of AA7075 sheet are established. Through the finite element numerical simulation of hot granules medium pressure forming（HGMF） process, not only the influence laws of the process parameters, such as forming temperature, the blank-holder gap and the diameter of the slab, on sheet metal forming performance are discussed, but also the broken area of the forming process is analyzed and predicted, which are coincided with the technological test. The conical part whose half cone angle is 15° and relative height H/d0 is 0.57, is formed in one process at 250℃. The HGMF process solves the problems of loading and seal in the existing flexible mould forming process and provides a novel technology for thermoforming of light alloy plate, such as magnesium alloy, aluminium alloy and titanium alloy.
