新能源因具备清洁、可再生等优点被越来越多地纳入现代电力系统。然而随着新能源发电占比不断增加,电力系统惯量减少,给电力系统频率稳定带来了极大的挑战。抽水蓄能电站(pumped hydropower energy storage,PHES)和电池储能(battery ene...新能源因具备清洁、可再生等优点被越来越多地纳入现代电力系统。然而随着新能源发电占比不断增加,电力系统惯量减少,给电力系统频率稳定带来了极大的挑战。抽水蓄能电站(pumped hydropower energy storage,PHES)和电池储能(battery energy storage,BES)都是重要的电力系统辅助调频手段,但单一的电池储能系统可能无法提供足够的惯量来有效地稳定电力系统的频率。基于此,本研究在电池储能中引入虚拟惯量控制(virtual synchronous control,VIC),开展了抽水蓄能与含虚拟惯量控制的电池储能下两区域互联电力系统LFC研究比较。首先,搭建了含抽水蓄能/电池储能的两区域互联电力系统LFC模型;然后,分别应用这2种方案在MATLAB/Simulink仿真实验平台上模拟了互联电力系统在新能源比例和负荷波动下的运行情况。仿真结果表明,电池储能LFC相对于传统LFC和抽水蓄能LFC在提高频率稳定性和动态响应能力方面更为优越。抽水蓄能仍具有一定的应用潜力,与电池储能结合使用,其负荷频率控制效果最佳。展开更多
脊髓损伤(SCI)发病率持续上升,高致残性导致严重功能障碍,给患者本身及社会带来沉重的负担。传统治疗面临瓶颈,硬膜外电刺激(EES)近年展现出突破性康复潜力,但其调控神经环路重塑的机制尚未系统阐明。本文检索PubMed、SinoMed、Web of S...脊髓损伤(SCI)发病率持续上升,高致残性导致严重功能障碍,给患者本身及社会带来沉重的负担。传统治疗面临瓶颈,硬膜外电刺激(EES)近年展现出突破性康复潜力,但其调控神经环路重塑的机制尚未系统阐明。本文检索PubMed、SinoMed、Web of Science、中国知网、万方等数据库建库至2024年文献,关键词包括"硬膜外电刺激"、"脊髓损伤"、"环路"、"epidural electrical stimulation"、"spinal cord injury"、"circuit",筛选机制研究及临床报道,并综述EES通过重塑神经环路改善SCI功能障碍的作用机制,以期为临床转化及深入研究提供理论依据。EES可通过对SCI上行环路、下行环路、脊髓固有环路进行重塑,从而改善SCI后功能障碍。EES可能还通过多层级神经环路重组促进功能恢复,但仍需大样本RCT验证疗效。未来应结合单细胞测序、光遗传学技术精准解析神经元亚群机制,探索EES联合干细胞移植、脑机接口及多靶点神经调控的协同策略。展开更多
目的分析肾炎康复片结合氯沙坦钾片治疗慢性肾小球肾炎的临床疗效及对IL-1β、IL-1及VEGF水平的影响。方法选择2016年11月—2019年12月医院收治的慢性肾小球肾炎患者85例,依据治疗方式的不同分为观察组43例和对照组42例,对照组患者入院...目的分析肾炎康复片结合氯沙坦钾片治疗慢性肾小球肾炎的临床疗效及对IL-1β、IL-1及VEGF水平的影响。方法选择2016年11月—2019年12月医院收治的慢性肾小球肾炎患者85例,依据治疗方式的不同分为观察组43例和对照组42例,对照组患者入院后给予口服氯沙坦钾片治疗。观察组患者在对照组治疗的基础上,口服肾炎康复片治疗。两组均连续治疗3个月。在治疗期间均低盐、低脂、低蛋白饮食。比较两组治疗疗效;比较两组患者临床症状改善时间;比较两组治疗前后血压、肾功能指标;比较两组治疗前后尿RBC、尿β2-MG和24 h Upro水平,比较两组治疗前、治疗3个月后血清IL-1β、IL-1及VEGF水平。结果观察组治疗总有效率为86.05%,显著高于对照组治疗总有效率的64.29%(P<0.05);观察组患者恶心呕吐时间、浮肿消失时间、疲惫消失时间均较对照组短(P<0.05);观察组治疗后SBP、DBP、BUN、Scr水平低于对照组,Alb水平高于对照组(P<0.05);观察组治疗后尿RBC、尿β2-MG和24 h Upro水平对照组(P<0.05);观察组治疗3个月后血清IL-1β、IL-1及VEGF水平低于对照组(P<0.05)。结论肾炎康复片结合氯沙坦钾片治疗慢性肾小球肾炎效果显著,可有效的改善临床症状,控制血压,减轻肾脏的免疫炎症损伤,延缓肾损伤进程减少蛋白尿,值得临床进一步研究探讨。展开更多
The parameters for the electro-deposition of Cu were optimized in order to increase the compressive properties of close cell aluminum. Different values of deposition voltages and times were considered to vary the amou...The parameters for the electro-deposition of Cu were optimized in order to increase the compressive properties of close cell aluminum. Different values of deposition voltages and times were considered to vary the amount of deposited Cu. The surface morphology of the coating was observed by SEM and the compressive properties were evaluated by MTS. The results show that the coating is more homogeneous and compact with increasing voltage in a certain range, and beyond which, the coating quality decreases apparently. The reason is dedicated to the discharge rate of Cu2+ and nucleus formed in unit time. The compression results show three experienced stages: elastic deformation stage, collapse deformation stage and densification stage. After the electro-deposition of Cu, the elasticity modulus is increased obviously and the platform stress is also increased. Under the same strain, the stress of the aluminum foam with coating is reinforced comparing with the aluminum foam without coating. Furthermore, the platform area is widened apparently. In addition, Cu-SiC nanocomposite coatings are electrodeposited in alumium foams for further improving the mechanical characterization.展开更多
文摘新能源因具备清洁、可再生等优点被越来越多地纳入现代电力系统。然而随着新能源发电占比不断增加,电力系统惯量减少,给电力系统频率稳定带来了极大的挑战。抽水蓄能电站(pumped hydropower energy storage,PHES)和电池储能(battery energy storage,BES)都是重要的电力系统辅助调频手段,但单一的电池储能系统可能无法提供足够的惯量来有效地稳定电力系统的频率。基于此,本研究在电池储能中引入虚拟惯量控制(virtual synchronous control,VIC),开展了抽水蓄能与含虚拟惯量控制的电池储能下两区域互联电力系统LFC研究比较。首先,搭建了含抽水蓄能/电池储能的两区域互联电力系统LFC模型;然后,分别应用这2种方案在MATLAB/Simulink仿真实验平台上模拟了互联电力系统在新能源比例和负荷波动下的运行情况。仿真结果表明,电池储能LFC相对于传统LFC和抽水蓄能LFC在提高频率稳定性和动态响应能力方面更为优越。抽水蓄能仍具有一定的应用潜力,与电池储能结合使用,其负荷频率控制效果最佳。
文摘目的分析肾炎康复片结合氯沙坦钾片治疗慢性肾小球肾炎的临床疗效及对IL-1β、IL-1及VEGF水平的影响。方法选择2016年11月—2019年12月医院收治的慢性肾小球肾炎患者85例,依据治疗方式的不同分为观察组43例和对照组42例,对照组患者入院后给予口服氯沙坦钾片治疗。观察组患者在对照组治疗的基础上,口服肾炎康复片治疗。两组均连续治疗3个月。在治疗期间均低盐、低脂、低蛋白饮食。比较两组治疗疗效;比较两组患者临床症状改善时间;比较两组治疗前后血压、肾功能指标;比较两组治疗前后尿RBC、尿β2-MG和24 h Upro水平,比较两组治疗前、治疗3个月后血清IL-1β、IL-1及VEGF水平。结果观察组治疗总有效率为86.05%,显著高于对照组治疗总有效率的64.29%(P<0.05);观察组患者恶心呕吐时间、浮肿消失时间、疲惫消失时间均较对照组短(P<0.05);观察组治疗后SBP、DBP、BUN、Scr水平低于对照组,Alb水平高于对照组(P<0.05);观察组治疗后尿RBC、尿β2-MG和24 h Upro水平对照组(P<0.05);观察组治疗3个月后血清IL-1β、IL-1及VEGF水平低于对照组(P<0.05)。结论肾炎康复片结合氯沙坦钾片治疗慢性肾小球肾炎效果显著,可有效的改善临床症状,控制血压,减轻肾脏的免疫炎症损伤,延缓肾损伤进程减少蛋白尿,值得临床进一步研究探讨。
基金Funded in Part by the Fundamental Research Funds for the Central Universities(Nos.300102318205,310831161020,310831163401)the National Natural Science Foundation of China(No.51301021)+2 种基金the China Postdoctoral Science Foundation(No.2016M592730)the Innovation and Entrepreneurship Training Program of Chang’an University(No.201610710084)the Fund of the State Key Laboratory of Solidification and Processing in Northwestern Polytechnical University(No.SKLSP201302)
文摘The parameters for the electro-deposition of Cu were optimized in order to increase the compressive properties of close cell aluminum. Different values of deposition voltages and times were considered to vary the amount of deposited Cu. The surface morphology of the coating was observed by SEM and the compressive properties were evaluated by MTS. The results show that the coating is more homogeneous and compact with increasing voltage in a certain range, and beyond which, the coating quality decreases apparently. The reason is dedicated to the discharge rate of Cu2+ and nucleus formed in unit time. The compression results show three experienced stages: elastic deformation stage, collapse deformation stage and densification stage. After the electro-deposition of Cu, the elasticity modulus is increased obviously and the platform stress is also increased. Under the same strain, the stress of the aluminum foam with coating is reinforced comparing with the aluminum foam without coating. Furthermore, the platform area is widened apparently. In addition, Cu-SiC nanocomposite coatings are electrodeposited in alumium foams for further improving the mechanical characterization.
